Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jeffrey W-D Foy, Robert A Schat. Inhibition of rat respiratory-tract cytochrome P-450 activity after acute low-level m-xylene inhalation: role in 1-nitronaphthalene toxicity. Inhalation toxicology. vol 16. issue 3. 2004-08-30. PMID:15204773. |
1-nn caused pronounced histopathological changes in both respiratory and olfactory regions of the nasal mucosa. |
2004-08-30 |
2023-08-12 |
rat |
Melonie Joanne Storan, Thierry Magnaldo, Marie-Claire Biol-N'Garagba, Yehiel Zick, Brian Ke. Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway. The Journal of comparative neurology. vol 475. issue 3. 2004-08-26. PMID:15221946. |
primary olfactory neurons project axons from the olfactory neuroepithelium lining the nasal cavity to the olfactory bulb in the brain. |
2004-08-26 |
2023-08-12 |
rat |
Melonie Joanne Storan, Thierry Magnaldo, Marie-Claire Biol-N'Garagba, Yehiel Zick, Brian Ke. Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway. The Journal of comparative neurology. vol 475. issue 3. 2004-08-26. PMID:15221946. |
galectin-4, -7, and -8 are expressed by the primary olfactory axons as they grow from the nasal cavity to the olfactory bulb. |
2004-08-26 |
2023-08-12 |
rat |
Liwei Wang, Churunal Hari, Lixin Chen, Tim Jaco. A new non-invasive method for recording the electro-olfactogram using external electrodes. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 115. issue 7. 2004-08-17. PMID:15203064. |
recording of human eog is technically difficult due to poor access to the olfactory mucosa and the nasal irritation is tolerated by few subjects. |
2004-08-17 |
2023-08-12 |
human |
D Shusterman, P C Avil. Real-time monitoring of nasal mucosal pH during carbon dioxide stimulation: implications for stimulus dynamics. Chemical senses. vol 28. issue 7. 2004-07-28. PMID:14578121. |
carbon dioxide is a commonly employed irritant test compound in nasal chemesthetic studies because it is essentially free of olfactory stimulus properties. |
2004-07-28 |
2023-08-12 |
human |
Gaëlle Guiraudie, Patrick Pageat, Anne-Hélène Cain, Iltud Madec, Patricia Nagnan-Le Meillou. Functional characterization of olfactory binding proteins for appeasing compounds and molecular cloning in the vomeronasal organ of pre-pubertal pigs. Chemical senses. vol 28. issue 7. 2004-07-28. PMID:14578123. |
we have used a ligand-oriented approach to functionally characterize olfactory binding proteins involved in the detection of appeasing compounds in the nasal mucosa (nm) and the vomeronasal organ (vno) of pre-pubertal pigs. |
2004-07-28 |
2023-08-12 |
Not clear |
Sarah K Williams, Tom Gilbey, Susan C Barnet. Immunohistochemical studies of the cellular changes in the peripheral olfactory system after zinc sulfate nasal irrigation. Neurochemical research. vol 29. issue 5. 2004-07-27. PMID:15139288. |
immunohistochemical studies of the cellular changes in the peripheral olfactory system after zinc sulfate nasal irrigation. |
2004-07-27 |
2023-08-12 |
Not clear |
Hansen L Wong, Sharon E Murphy, Stephen S Hech. Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes. Chemical research in toxicology. vol 16. issue 10. 2004-07-19. PMID:14565771. |
in this study, the kinetics of tritium-labeled npip or npyr alpha-hydroxylation mediated by sprague-dawley rat nasal olfactory or respiratory microsomes were investigated. |
2004-07-19 |
2023-08-12 |
human |
Hansen L Wong, Sharon E Murphy, Stephen S Hech. Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes. Chemical research in toxicology. vol 16. issue 10. 2004-07-19. PMID:14565771. |
in conclusion, olfactory and respiratory microsomes from rat nasal mucosa preferentially activate npip over npyr with p450 2a3 likely playing a key role. |
2004-07-19 |
2023-08-12 |
human |
B N Landis, T Hummel, M Hugentobler, R Giger, J S Lacroi. Ratings of overall olfactory function. Chemical senses. vol 28. issue 8. 2004-07-16. PMID:14627537. |
such ratings were compared with quantitative measures of olfactory function, as well as with ratings of nasal patency. |
2004-07-16 |
2023-08-12 |
human |
B N Landis, T Hummel, M Hugentobler, R Giger, J S Lacroi. Ratings of overall olfactory function. Chemical senses. vol 28. issue 8. 2004-07-16. PMID:14627537. |
in experiment 1 subjects rated olfactory function and nasal patency before olfactory testing, whereas in experiment 2 the reverse was the case. |
2004-07-16 |
2023-08-12 |
human |
B N Landis, T Hummel, M Hugentobler, R Giger, J S Lacroi. Ratings of overall olfactory function. Chemical senses. vol 28. issue 8. 2004-07-16. PMID:14627537. |
however, ratings of olfactory function correlated significantly with ratings of nasal airway patency. |
2004-07-16 |
2023-08-12 |
human |
B N Landis, T Hummel, M Hugentobler, R Giger, J S Lacroi. Ratings of overall olfactory function. Chemical senses. vol 28. issue 8. 2004-07-16. PMID:14627537. |
now ratings of olfactory function correlated significantly with measured olfactory function, whereas there was no significant correlation between ratings of nasal airway patency and ratings of olfactory function. |
2004-07-16 |
2023-08-12 |
human |
B N Landis, T Hummel, M Hugentobler, R Giger, J S Lacroi. Ratings of overall olfactory function. Chemical senses. vol 28. issue 8. 2004-07-16. PMID:14627537. |
the ratings seem to reflect changes of nasal airway patency to a larger degree than measurable olfactory function. |
2004-07-16 |
2023-08-12 |
human |
C Philpott, P Goodenough, C Passant, A Robertson, G Murt. The effect of temperature, humidity and peak inspiratory nasal flow on olfactory thresholds. Clinical otolaryngology and allied sciences. vol 29. issue 1. 2004-07-15. PMID:14961848. |
the effect of temperature, humidity and peak inspiratory nasal flow on olfactory thresholds. |
2004-07-15 |
2023-08-12 |
human |
C Philpott, P Goodenough, C Passant, A Robertson, G Murt. The effect of temperature, humidity and peak inspiratory nasal flow on olfactory thresholds. Clinical otolaryngology and allied sciences. vol 29. issue 1. 2004-07-15. PMID:14961848. |
temperature, humidity and nasal peak inspiratory flow rate (pifr) are potential variables in the quantitative measurement of olfactory thresholds in the clinic. |
2004-07-15 |
2023-08-12 |
human |
C Philpott, P Goodenough, C Passant, A Robertson, G Murt. The effect of temperature, humidity and peak inspiratory nasal flow on olfactory thresholds. Clinical otolaryngology and allied sciences. vol 29. issue 1. 2004-07-15. PMID:14961848. |
this demonstrated that olfactory thresholds are sufficiently independent of room temperature, peak humidity and nasal pifr in a routine outpatient clinic environment in normal subjects, with no evidence of any statistically significant influence by these variables. |
2004-07-15 |
2023-08-12 |
human |
Guoyu Ling, Jun Gu, Mary Beth Genter, Xiaoliang Zhuo, Xinxin Din. Regulation of cytochrome P450 gene expression in the olfactory mucosa. Chemico-biological interactions. vol 147. issue 3. 2004-07-06. PMID:15135081. |
our goal is to stimulate further studies in this exciting research area, which is of considerable importance, in view of the constant exposure of the human nasal tissues to inhaled, as well as systemically derived, chemicals, the prevalence of olfactory system damage in individuals with neurodegenerative diseases, and the current uncertainty in risk assessments for potential olfactory toxicants. |
2004-07-06 |
2023-08-12 |
human |
Xueyong Wang, Jinshu Yin, Suoqiang Zha. [Factors that affect the improvement of olfactory function after endoscopic sinus surgery in patients suffering from chronic sinusitis and/or nasal polyps]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology. vol 17. issue 10. 2004-07-02. PMID:14727434. |
[factors that affect the improvement of olfactory function after endoscopic sinus surgery in patients suffering from chronic sinusitis and/or nasal polyps]. |
2004-07-02 |
2023-08-12 |
Not clear |
Po C Chan, Joel Mahler, Shyamal Peddada, Liat Lomnitski, Abraham Nysk. Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice. Archives of toxicology. vol 77. issue 9. 2004-06-30. PMID:12879212. |
in the 14-week studies the chemical induced forestomach hyperplasia and nasal olfactory atrophy or necrosis at 120 mg/kg in rats and mice. |
2004-06-30 |
2023-08-12 |
mouse |