| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph R Raviv, Robert C Ker. Chronic sinusitis and olfactory dysfunction. Otolaryngologic clinics of North America. vol 37. issue 6. 2005-03-03. PMID:15563907. |
in addition to nasal obstruction and discharge, chronic sinusitis is a common cause of olfactory dysfunction. |
2005-03-03 |
2023-08-12 |
Not clear |
| Evan R Reiter, Laurence J DiNardo, Richard M Costanz. Effects of head injury on olfaction and taste. Otolaryngologic clinics of North America. vol 37. issue 6. 2005-03-03. PMID:15563909. |
evaluation of head-injured patients presenting with olfactory or gustatory complaints should include a thorough history, including assessment for pre-and posttraumatic chemosensory dysfunction and potential mechanisms of injury, complete head and neck examination including nasal endoscopy and cranial nerve testing, and focused radiographic imaging, usually ct of the sinuses and skull base. |
2005-03-03 |
2023-08-12 |
Not clear |
| Evan R Reiter, Laurence J DiNardo, Richard M Costanz. Effects of head injury on olfaction and taste. Otolaryngologic clinics of North America. vol 37. issue 6. 2005-03-03. PMID:15563909. |
treatable causes of chemosensory disturbance, most notably conductive olfactory losses caused by chronic rhinosinusitis or nasal obstruction, should be ruled out. |
2005-03-03 |
2023-08-12 |
Not clear |
| Mary Beth Gente. Update on olfactory mucosal metabolic enzymes: age-related changes and N-acetyltransferase activities. Journal of biochemical and molecular toxicology. vol 18. issue 4. 2005-02-16. PMID:15452881. |
these studies show that the olfactory mucosa varies in its metabolic capacity with age, and characterize another class of metabolic enzymes in the olfactory mucosa, both of which may impact significantly on responses to toxicants and therapeutic agents in the nasal cavity. |
2005-02-16 |
2023-08-12 |
rat |
| John B Morris, Marcy I Banton, Lynn H Pottenge. Uptake of inspired propylene oxide in the upper respiratory tract of the f344 rat. Toxicological sciences : an official journal of the Society of Toxicology. vol 81. issue 1. 2005-02-15. PMID:15201440. |
since depletion of nasal non-protein sulfhydryls (npsh) may be important in the toxicity of this vapor and may serve as a biomarker for delivery of propylene oxide to nasal tissues, measurements of respiratory and olfactory npsh content after propylene oxide exposure were also made. |
2005-02-15 |
2023-08-12 |
rat |
| John B Morris, Marcy I Banton, Lynn H Pottenge. Uptake of inspired propylene oxide in the upper respiratory tract of the f344 rat. Toxicological sciences : an official journal of the Society of Toxicology. vol 81. issue 1. 2005-02-15. PMID:15201440. |
immediately after exposure, nasal respiratory and olfactory tissues were removed and analyzed for npsh content. |
2005-02-15 |
2023-08-12 |
rat |
| Zsófia Hoyk, Arpád Párducz, Luis Miguel Garcia-Segur. Dehydroepiandrosterone regulates astroglia reaction to denervation of olfactory glomeruli. Glia. vol 48. issue 3. 2005-02-10. PMID:15390121. |
denervation was achieved by destroying the olfactory mucosa with znso(4) (0.17 m) irrigation of the nasal cavities. |
2005-02-10 |
2023-08-12 |
rat |
| Eva Tydén, Hans Tjälve, Pia Larsso. Metabolic activation of 2,6-xylidine in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts in rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 81. issue 2. 2005-02-04. PMID:15254337. |
metabolic activation of 2,6-xylidine in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts in rats. |
2005-02-04 |
2023-08-12 |
rat |
| Eva Tydén, Hans Tjälve, Pia Larsso. Metabolic activation of 2,6-xylidine in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts in rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 81. issue 2. 2005-02-04. PMID:15254337. |
whole-body autoradiography with freeze-dried or solvent-extracted tissue sections as well as microautoradiography, which were used to trace tissues in the rats accumulating 2,6-xylidine metabolites, showed presence of tissue-bound 2,6-xylidine metabolites in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts. |
2005-02-04 |
2023-08-12 |
rat |
| Eva Tydén, Hans Tjälve, Pia Larsso. Metabolic activation of 2,6-xylidine in the nasal olfactory mucosa and the mucosa of the upper alimentary and respiratory tracts in rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 81. issue 2. 2005-02-04. PMID:15254337. |
our results showed that the nasal olfactory mucosa had a much higher capacity than the other examined tissues to bioactivate 2,6-xylidine. |
2005-02-04 |
2023-08-12 |
rat |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
recent studies that have compared ct or mri images of an individual's nasal anatomy and measures of their olfactory sensitivity have found a correlation between specific anatomical areas and performance on olfactory assessments. |
2005-01-31 |
2023-08-12 |
human |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
using computational fluid dynamics (cfd) techniques, we have developed a method to quickly (nasal ct scans from an individual patient into an anatomically accurate 3-d numerical nasal model that can be used to predict airflow and odorant transport, which may ultimately determine olfactory sensitivity. |
2005-01-31 |
2023-08-12 |
human |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
the 3-d model can be also be rapidly modified to depict various anatomical deviations, such as polyps and their removal, that may alter nasal airflow and impair olfactory ability. |
2005-01-31 |
2023-08-12 |
human |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
to evaluate the degree to which variations in critical nasal areas such as the olfactory slit and nasal valve can alter airflow and odorant transport, inspiratory and expiratory airflow with odorants were simulated using numerical finite volume methods. |
2005-01-31 |
2023-08-12 |
human |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
results suggest that anatomical changes in the olfactory region (upper meatus below the cribriform plate) and the nasal valve region will strongly affect airflow patterns and odorant transport through the olfactory region, with subsequent effects on olfactory function. |
2005-01-31 |
2023-08-12 |
human |
| Kai Zhao, Peter W Scherer, Shoreh A Hajiloo, Pamela Dalto. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chemical senses. vol 29. issue 5. 2005-01-31. PMID:15201204. |
the ability to model odorant transport through individualized models of the nasal passages holds promise for relating anatomical deviations to generalized or selective disturbances in olfactory perception and may provide important guidance for treatments for nasal-sinus disease, occupational rhinitis and surgical interventions that seek to optimize airflow and improve deficient olfactory function. |
2005-01-31 |
2023-08-12 |
human |
| Paul J Moberg, David R Roalf, Raquel E Gur, Bruce I Turetsk. Smaller nasal volumes as stigmata of aberrant neurodevelopment in schizophrenia. The American journal of psychiatry. vol 161. issue 12. 2005-01-28. PMID:15569907. |
since olfactory structures develop in conjunction with both the palate and ventral forebrain, the authors hypothesized that schizophrenia patients might have structural abnormalities of the nasal cavity, which could represent specific markers of embryological dysmorphogenesis underlying schizophrenia. |
2005-01-28 |
2023-08-12 |
Not clear |
| Linda B Buc. Olfactory receptors and odor coding in mammals. Nutrition reviews. vol 62. issue 11 Pt 2. 2005-01-25. PMID:15630933. |
another olfactory structure in the nasal septum of animals, the vomeronasal organ, has two additional receptor families that detect pheromones and induce hormonal and behavioral responses through a different projection to the brain. |
2005-01-25 |
2023-08-12 |
mouse |
| J Lewis, G Bench, O Myers, B Tinner, W Staines, E Barr, K K Divine, W Barrington, J Karlsso. Trigeminal uptake and clearance of inhaled manganese chloride in rats and mice. Neurotoxicology. vol 26. issue 1. 2005-01-11. PMID:15527879. |
in addition to olfactory neurons, the nasal cavity is innervated by the maxillary division of the trigeminal nerve that projects to the spinal trigeminal nucleus. |
2005-01-11 |
2023-08-12 |
mouse |
| Melonie J Storan, Brian Ke. Target tissue influences the peripheral trajectory of mouse primary sensory olfactory axons. Journal of neurobiology. vol 61. issue 2. 2005-01-07. PMID:15389690. |
primary olfactory neurons situated in the nasal septum project axons within fascicles along a highly stereotypical trajectory en route to the olfactory bulb. |
2005-01-07 |
2023-08-12 |
mouse |