| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhanglei Dong, Saiqiong Xiang, Chi Pan, Chenchen Jiang, Suhao Bao, Wangning Shangguan, Ruifeng Zeng, Jun Li, Qingquan Lian, Binbin W. The excitatory transmission from basolateral nuclues of amygdala to nucleus accumbens shell regulates propofol self-administration through AMPA receptors. Addiction biology. vol 28. issue 8. 2023-07-27. PMID:37500486. |
the glutamatergic transmission from basolateral nucleus of amygdala (bla) to the nucleus accumbens (nac) modulates reward-seeking behaviour; especially, nac shell (nash) is implicated in reward-seeking response. |
2023-07-27 |
2023-08-14 |
rat |
| Michael W Gongwer, Cassandra B Klune, João Couto, Benita Jin, Alexander S Enos, Rita Chen, Drew Friedmann, Laura A DeNard. Brain-wide projections and differential encoding of prefrontal neuronal classes underlying learned and innate threat avoidance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-25. PMID:37491314. |
using tissue clearing and light sheet fluorescence microscopy, we mapped the brain-wide axon collaterals of populations of mpfc neurons that project to nucleus accumbens (nac), ventral tegmental area (vta), or contralateral mpfc (cmpfc). |
2023-07-25 |
2023-08-14 |
mouse |
| Joakim W Ronström, Stephanie B Williams, Andrew Payne, Daniel J Obray, Caylor Hafen, Matthew Burris, K Scott Weber, Scott C Steffensen, Jordan T Yorgaso. Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine release. Brain, behavior, and immunity. 2023-07-15. PMID:37453452. |
dopamine transmission from the ventral tegmental area (vta) to the nucleus accumbens (nac) regulates important aspects of motivation and is influenced by the neuroimmune system. |
2023-07-15 |
2023-08-14 |
Not clear |
| Sriparna Ghosal, Elias Gebara, Eva Ramos-Fernández, Alessandro Chioino, Jocelyn Grosse, Isabelle Guillot de Suduiraut, Olivia Zanoletti, Bernard Schneider, Antonio Zorzano, Simone Astori, Carmen Sand. Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function. Cell reports. vol 42. issue 7. 2023-07-13. PMID:37440411. |
the nucleus accumbens (nac) is a brain hub regulating motivated behaviors, including social competitiveness. |
2023-07-13 |
2023-08-14 |
mouse |
| Juan Enriquez-Traba, Hector E Yarur-Castillo, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Miguel Arenivar, Huikun Wang, Valerie S Tsai, Amy E Moritz, David R Sibley, Rosario Moratalla, Zachary Z Freyberg, Hugo A Tejed. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425766. |
dopamine release in striatal circuits, including the nucleus accumbens (nac), tracks separable features of reward such as motivation and reinforcement. |
2023-07-10 |
2023-08-14 |
Not clear |
| Julie-Anne Balouek, Christabel A Mclain, Adelaide R Minerva, Rebekah L Rashford, Shannon N Bennett, Forrest D Rogers, Catherine Jensen Peñ. Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-10. PMID:37429717. |
we found that in both male and female mice, els-activated neurons within the nucleus accumbens (nac), and to a lesser-extent the medial prefrontal cortex, were preferentially reactivated by adult stress. |
2023-07-10 |
2023-08-14 |
mouse |
| Daniela Neuhofer, Peter Kaliva. Differential modulation of GABAergic and glutamatergic neurons in the ventral pallidum by GABA and neuropeptides. eNeuro. 2023-07-06. PMID:37414552. |
the ventral pallidum (vp) is an integral locus in the reward circuitry and a major target of gabaergic innervation of both d1-medium spiny neurons (msns) and d2-msns from the nucleus accumbens (nac). |
2023-07-06 |
2023-08-14 |
mouse |
| Astrid M Cardona-Acosta, Omar K Sial, Lyonna F Parise, Tamara Gnecco, Giselle Enriquez Marti, Carlos A Bolaños-Guzmá. Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway. Scientific reports. vol 13. issue 1. 2023-07-05. PMID:37407659. |
in a separate experiment, mice received alp (0, 0.5 mg/kg) and then sacrificed 24-h or 1-month after treatment to assess levels of extracellular signal regulated kinase 1/2 (erk1/2) gene expression, protein phosphorylation, and downstream targets (creb, akt) within the ventral tegmental area (vta) and nucleus accumbens (nac). |
2023-07-05 |
2023-08-14 |
mouse |
| Mathilde C C Guillaumin, Paulius Viskaitis, Eva Bracey, Denis Burdakov, Daria Peleg-Raibstei. Disentangling the role of NAc D1 and D2 cells in hedonic eating. Molecular psychiatry. 2023-07-04. PMID:37402855. |
the nucleus accumbens (nac) is a key brain center implicated in these processes, but how distinct nac cell populations encode 'liking' and 'wanting' to shape overconsumption remains unclear. |
2023-07-04 |
2023-08-14 |
mouse |
| Yuan-Yuan Han, Jian-Wen Zhou, Zhi-Wei Guo, Zhuo-Qing Wu, Zai-Yong Zhang, De-Xiang Liu, Cheng Lon. Multiple brain regions are involved in reaction to acute restraint stress in CYLD-knockout mice. Stress (Amsterdam, Netherlands). vol 26. issue 1. 2023-07-03. PMID:37395260. |
here we report that cyld deficiency leads to an unexpected reaction to ars in mice, and is accompanied by significant neuronal activation of brain regions including the medial prefrontal cortex (mpfc), dorsal striatum (ds), nucleus accumbens (nac), and basal lateral amygdala (bla), but not ventral hippocampus (vhpc). |
2023-07-03 |
2023-08-14 |
mouse |
| Metika L Ngbokoli, Joaquin E Douton, Regina M Carell. Prelimbic cortex and nucleus accumbens core resting state signaling dynamics as a biomarker for cocaine seeking behaviors. Addiction neuroscience. vol 7. 2023-07-03. PMID:37396409. |
here, in vivo local field potential (lfp) electrophysiology was used in rats to examine the relationship between overall spontaneous (resting state) activity within the prelimbic cortex (prl) and nucleus accumbens (nac) core, and their functional connectivity, to cocaine taking and seeking behaviors. |
2023-07-03 |
2023-08-14 |
rat |
| Jimmy Olusakin, Gautam Kumar, Mahashweta Basu, Cali A Calarco, Megan E Fox, Jason B Alipio, Catherine Haga, Makeda D Turner, Asaf Keller, Seth A Ament, Mary Kay Lob. Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-03. PMID:37400565. |
rna was extracted from nucleus accumbens (nac), prelimbic cortex (prl), ventral tegmental area (vta), somatosensory cortex (s1) and ventrobasal thalamus (vbt) from perinatal fentanyl exposed mice of both sexes at p35. |
2023-07-03 |
2023-08-14 |
mouse |
| Jiyoung S Kim, Kevin C Williams, Rebecca A Kirkland, Ruth Schade, Kimberly G Freeman, Carolina R Cawthon, Allison W Rautmann, Jessica M Smith, Gaylen L Edwards, Travis C Glenn, Philip V Holmes, Guillaume de Lartigue, Claire B de La Serr. The gut-brain axis mediates bacterial driven modulation of reward signaling. Molecular metabolism. 2023-06-28. PMID:37380023. |
convhf rats displayed lower feeding-induced extracellular dopac levels (a metabolite of dopamine) in the nucleus accumbens (nac) as well as reduced motivation for hf foods compared to convlf rats. |
2023-06-28 |
2023-08-14 |
rat |
| Laura Santana Cordón, Domingo Afonso-Oramas, Alejandro Lemus Mesa, Miriam González-Gómez, Pedro Barroso-Chine. Morphological study of neuropeptide Y expression in human and mouse anterior insular cortex: overexpression in the insular cortex and nucleus accumbens in obese mice on a long-term obesogenic diet. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2023-06-24. PMID:37355144. |
the anterior lobe of the insular cortex (ains) is a cortical region that has reciprocal connections with limbic centers such as the anterior cingulate cortex, prefrontal cortex, amygdala and nucleus accumbens (nac). |
2023-06-24 |
2023-08-14 |
mouse |
| Amanda M Catalfio, Tracy L Fetterly, Allison M Nieto, Terry E Robinson, Carrie R Ferrari. Cocaine-induced sensitization and glutamate plasticity in the nucleus accumbens core: effects of sex. Biology of sex differences. vol 14. issue 1. 2023-06-24. PMID:37355656. |
the development and persistence of addiction is mediated in part by drug-induced alterations in nucleus accumbens (nac) function. |
2023-06-24 |
2023-08-14 |
Not clear |
| Yafang Zhang, Jennifer Ben Nathan, Amanda Moreno, Riley Merkel, Michelle W Kahng, Matthew R Hayes, Benjamin C Reiner, Richard C Crist, Heath D Schmid. Calcitonin receptor signaling in nucleus accumbens D1R- and D2R-expressing medium spiny neurons bidirectionally alters opioid taking in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-24. PMID:37355732. |
here, we used single nuclei rna sequencing (snrna-seq), fluorescent in situ hybridization (fish), and immunohistochemistry (ihc) to characterize cell type-specific patterns of ctr expression in the nucleus accumbens (nac), a brain region that plays a critical role in voluntary drug taking. |
2023-06-24 |
2023-08-14 |
rat |
| Jing Yan, Bei-Ning Hang, Lin-Hui Ma, Jia-Tao Lin, Yue Zhou, Xin-Hao Jiao, Ying-Xuan Yuan, Ke-Jie Shao, Le-Meng Zhang, Qi Xue, Zi-Yi Li, Hong-Xing Zhang, Jun-Li Cao, Shuai Li, Hui Zheng, Yu-Qing W. GABAergic Neurons in the Nucleus Accumbens are Involved in the General Anesthesia Effect of Propofol. Molecular neurobiology. 2023-06-22. PMID:37349621. |
in essence, the nucleus accumbens (nac) is crucial for regulating wakefulness and may be directly engaged in the principle of general anesthesia. |
2023-06-22 |
2023-08-14 |
Not clear |
| Federica Lucantonio, Shuwen Li, Jaden Lu, Jacob Roeglin, Leonardo Bontempi, Brenda C Shields, Carlos A Zarate, Michael R Tadross, Marco Pignatell. Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333325. |
here, we show that the nucleus accumbens (nac), a major hub of the reward circuitry, is essential for ketamine's effect in rescuing anhedonia in mice subjected to chronic stress, a critical risk factor in the genesis of depression in humans. |
2023-06-19 |
2023-08-14 |
mouse |
| Liping Ma, He Liu, Ziyi Xu, Mengli Yang, Yinghua Zhan. Application of the WholeBrain Calculation Interactive Framework to Map Whole-Brain Neural Connectivity Networks. Journal of chemical neuroanatomy. 2023-06-18. PMID:37331669. |
wild-type c57bl/6j mice (n = 10) aged 8-10 weeks were injected with the cholera toxin subunit b (ctb) tracer in the anterior (nacca) and posterior (naccp) parts of the nucleus accumbens (nac) core and in the medial (nacsm) and lateral (nacsl) parts of the nac shell. |
2023-06-18 |
2023-08-14 |
mouse |
| Ali R Rezai, James J Mahoney, Manish Ranjan, Marc W Haut, Wanhong Zheng, Laura R Lander, James H Berry, Daniel L Farmer, Jennifer L Marton, Padma Tirumalai, Ashley Mears, Daisy G Y Thompson-Lake, Victor S Finomore, Pierre-François D'Haese, Will M Aklin, David T George, John D Corrigan, Sally L Hodde. Safety and feasibility clinical trial of nucleus accumbens deep brain stimulation for treatment-refractory opioid use disorder. Journal of neurosurgery. 2023-06-17. PMID:37329519. |
the objective of this study was to evaluate the safety and feasibility of deep brain stimulation (dbs) targeting the nucleus accumbens (nac)/ventral capsule (vc) and potential impact on outcomes in individuals with treatment-refractory oud. |
2023-06-17 |
2023-08-14 |
Not clear |