| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel J Lodge, Hannah B Elam, Angela M Boley, Jennifer J Donega. Discrete hippocampal projections are differentially regulated by parvalbumin and somatostatin interneurons. Nature communications. vol 14. issue 1. 2023-10-20. PMID:37863893. |
first, we use egrasp to show that pv-positive interneurons form a similar number of synaptic connections with pyramidal cells regardless of their projection target while sst-positive interneurons preferentially target nucleus accumbens (nac) projections. |
2023-10-20 |
2023-11-08 |
Not clear |
| Xiaonan Li, Lehua Lu, Ying He, Hui Zhang, Yihui Zhang, Huaquan Sheng, Ming Chen, Jiexiong Ru, Yihan Ga. Pharmacological effects of nicotine salts on dopamine release in the nucleus accumbens. Frontiers in pharmacology. vol 14. 2023-10-16. PMID:37841907. |
nicotine increases the release of dopamine (da) into the nucleus accumbens (nac), causing feelings of satisfaction. |
2023-10-16 |
2023-11-08 |
mouse |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |
| Jong Hyeon Ahn, Junmo Kwon, Ji Hye Won, Kyoungseob Byeon, Jinyoung Youn, Hyunjin Park, Jin Whan Ch. Waiting impulsivity in progressive supranuclear palsy-Richardson's syndrome. Frontiers in neuroscience. vol 17. 2023-10-11. PMID:37817800. |
waiting impulsivity in progressive supranuclear palsy-richardson's syndrome (psp-rs) is difficult to assess, and its regulation is known to involve nucleus accumbens (nac) subregions. |
2023-10-11 |
2023-10-15 |
Not clear |
| Megan Ulmer Carnes, Bryan C Quach, Linran Zhou, Shizhong Han, Ran Tao, Meisha Mandal, Amy Deep-Soboslay, Jesse A Marks, Grier P Page, Brion S Maher, Andrew E Jaffe, Hyejung Won, Laura J Bierut, Thomas M Hyde, Joel E Kleinman, Eric O Johnson, Dana B Hancoc. Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci. medRxiv : the preprint server for health sciences. 2023-10-04. PMID:37790540. |
we used genome-wide genotype, dna methylation, and rna sequencing data in postmortem human nucleus accumbens (nac) to identify |
2023-10-04 |
2023-10-07 |
human |
| Zubeyde Ercan, Ozgur Bulmus, Emine Kacar, Ihsan Serhatlioglu, Gokhan Zorlu, Haluk Kelestimu. Treadmill Exercise Improves Behavioral and Neurobiological Alterations in Restraint-Stressed Rats. Journal of molecular neuroscience : MN. 2023-10-04. PMID:37794307. |
crs reduced the dopamine levels in the nucleus accumbens(nac). |
2023-10-04 |
2023-10-07 |
rat |
| James J Mahoney, Marc W Haut, Jeffrey Carpenter, Manish Ranjan, Daisy G Y Thompson-Lake, Jennifer L Marton, Wanhong Zheng, James H Berry, Padma Tirumalai, Ashley Mears, Pierre D'Haese, Victor S Finomore, Sally L Hodder, Ali R Reza. Low-intensity focused ultrasound targeting the nucleus accumbens as a potential treatment for substance use disorder: safety and feasibility clinical trial. Frontiers in psychiatry. vol 14. 2023-10-02. PMID:37779628. |
this study evaluated two doses (60 and 90 w) of low intensity focused ultrasound (lifu), targeting the bilateral nucleus accumbens (nac), in individuals with sud. |
2023-10-02 |
2023-10-07 |
Not clear |
| Caleb J Browne, Philipp Mews, Xianxiao Zhou, Leanne M Holt, Molly Estill, Rita Futamura, Anne Schaefer, Paul J Kenny, Yasmin L Hurd, Li Shen, Bin Zhang, Eric J Nestle. Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine. bioRxiv : the preprint server for biology. 2023-10-02. PMID:37781621. |
substance use disorders (suds) induce widespread molecular dysregulation in the nucleus accumbens (nac), a brain region pivotal for coordinating motivation and reward. |
2023-10-02 |
2023-10-07 |
Not clear |
| Sofia Beas, Isbah Khan, Claire Gao, Emma McDonnald, Alison Bashford, Shakira Rodriguez-Gonzalez, Mario A Penz. Dissociable encoding of motivated behavior by parallel thalamo-striatal projections. bioRxiv : the preprint server for biology. 2023-10-02. PMID:37781624. |
the paraventricular nucleus of the thalamus (pvt) is a midline thalamic nucleus that shapes motivated behaviors via its projections to the nucleus accumbens (nac) |
2023-10-02 |
2023-10-07 |
Not clear |
| Jiahui Ma, Xiaoling Huang, Zhenxing Li, Saiying Wang, Xuebin Yan, Dong Huang, Haocheng Zho. Photic Sensitization is Mediated by Cortico-Accumbens Pathway in Rats with Trigeminal Neuropathic Pain. Progress in neurobiology. 2023-09-30. PMID:37776970. |
additionally, this behavioral phenotype of light-sensitivity impairment was associated with overexpression of anterior cingulate cortex (acc) c-fos positive neurons, enhancement of neural excitability in the acc neurons and its excitatory synaptic transmission between nucleus accumbens (nac). |
2023-09-30 |
2023-10-07 |
rat |
| Yasmin Olsson, Helga Lidö, Karin Ademar, Davide Cadeddu, Mia Ericson, Bo Söderpal. The GlyT1-inhibitor Org 24598 facilitates the alcohol deprivation abolishing and dopamine elevating effects of bupropion + varenicline in rats. Journal of neural transmission (Vienna, Austria : 1996). 2023-09-29. PMID:37773223. |
also, direct and indirect glycine receptor (glyr) agonists raise basal da, attenuate alcohol-induced da release in the nucleus accumbens (nac) and reduce alcohol consumption in rats. |
2023-09-29 |
2023-10-07 |
rat |
| Kristyn N Borrelli, Kelly K Wingfield, Emily J Yao, Catalina A Zamorano, Katherine D Sena, Jacob A Beierle, Michelle A Roos, Huiping Zhang, Elisha M Wachman, Camron D Bryan. Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. Neuropharmacology. 2023-09-29. PMID:37774943. |
we used a third trimester-approximate model in which neonatal outbred pups (carworth farms white; cfw) were administered once-daily morphine (15 mg/kg, s.c.) from postnatal day (p) day 1 through p14 and were then assessed for behavioral and transcriptomic adaptations within the nucleus accumbens (nac) on p15. |
2023-09-29 |
2023-10-07 |
mouse |
| Gavin C Jones, Christina A Small, Dallin Z Otteson, Caylor W Hafen, Jacob T Breinholt, Paul D Flora, Matthew D Burris, David W Sant, Tysum R Ruchti, Jordan T Yorgason, Scott C Steffensen, Kyle B Bill. Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762450. |
peripheral mechanoreceptor-based treatments such as acupuncture and chiropractic manipulation have shown success in modulating the mesolimbic dopamine (da) system originating in the ventral tegmental area (vta) of the midbrain and projecting to the nucleus accumbens (nac) of the striatum. |
2023-09-28 |
2023-10-07 |
rat |
| Sarah M Barry, Gabriella M Barry, Dalia Martinez, Rachel D Penrod, Christopher W Cowa. The activity-regulated cytoskeleton-associated protein, Arc, functions in the nucleus accumbens shell to limit multiple triggers of cocaine-seeking behaviour. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753560. |
the activity-regulated cytoskeleton-associated protein (arc) is induced by cocaine in the nucleus accumbens (nac), an important brain reward region, but arc's nac function in sud-related behaviour remains unclear. |
2023-09-27 |
2023-10-07 |
rat |
| Suchan Chang, Hyung Kyu Kim, Yeonhee Ryu, Han Byeol Jang, DanBi Ahn, Bong Hyo Lee, Dong-Ho Youn, Bae Hwan Lee, Hee Young Ki. Mediation of mPFC-LHb pathway in acupuncture inhibition of cocaine psychomotor activity. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753567. |
to explore whether an mpfc-lhb circuit mediates the inhibitory effects of acupuncture on addictive behaviours, we examined the projection from mpfc to lhb, excitation of mpfc neurons during acupuncture stimulation, the effects of optogenetic modulation of mpfc-lhb on ht7 inhibition of cocaine-induced locomotion and the effect of mpfc lesion on ht7 inhibition of nucleus accumbens (nac) dopamine release. |
2023-09-27 |
2023-10-07 |
rat |
| Anna E Ingebretson, Julia C Lemo. Corticotropin releasing factor alters the functional diversity of accumbal cholinergic interneurons. bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745598. |
here, we investigated the spontaneous firing patterns of chis in the nucleus accumbens (nac) shell, a region of the ventral striatum. |
2023-09-25 |
2023-10-07 |
mouse |
| M I Airapetov, S O Eresko, S A Shamaeva, N M Matveev, E R Bychkov, A A Lebedev, P D Shabano. Prolonged alcohol consumption influences microRNA expression in the nucleus accumbens of the rat brain. Biomeditsinskaia khimiia. vol 69. issue 4. 2023-09-14. PMID:37705484. |
we have investigated the expression levels of mir-let7b, mir-96, mir-182, mir-155, and the mrna content of hmgb1, tlr3, tlr4 in the nucleus accumbens (nac) of the brain of rats exposed to long-term alcoholization. |
2023-09-14 |
2023-10-07 |
rat |
| Enzo Pérez-Valenzuela, Roger Hudson, Taygun Uzuneser, Marta De Felice, Hanna Szkudlarek, Walter Rushlow, Steven R Laviolett. Sex-Dependent Synergism of an Edible THC: CBD Formulation in Reducing Anxiety and Depressive-like Symptoms Following Chronic Stress. Current neuropharmacology. 2023-09-13. PMID:37702237. |
furthermore, western-blot experiments examined the expression of biomarkers associated with mood and anxiety disorders, including protein kinase b (akt), glycogen synthase kinase-3 (gsk-3), bdnf, mtor, d1, and d2 receptor in nucleus accumbens (nac) and pfc.edible thc:cbd produces significant anxiolytic and antidepressant effects only in stressed male rats. |
2023-09-13 |
2023-10-07 |
rat |
| Zachary W Hoisington, Alexandra Salvi, Sophie Laguesse, Yann Ehinger, Chhavi Shukla, Khanhky Phamluong, Dorit Ro. The small G-protein Rac1 in the dorsomedial striatum promotes alcohol-dependent structural plasticity and goal-directed learning in mice. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693512. |
actin is a major component of dendritic spines, and we previously found that alcohol alters actin composition and dendritic spine structure in the nucleus accumbens (nac) and the dorsomedial striatum (dms). |
2023-09-11 |
2023-10-07 |
mouse |
| Jing Jin, Xiu-Qin Wang, Xue Yang, Na Zhao, Zi-Jian Feng, Yu-Feng Zang, Li-Xia Yua. Abnormal individualized peak functional connectivity toward potential repetitive transcranial magnetic stimulation treatment of autism spectrum disorder. Human brain mapping. 2023-09-11. PMID:37694907. |
the nucleus accumbens (nac) was regarded as a promising effective region, which was used as a seed and individualized peak fc strength in the dlpfc was compared between asd and tdc. |
2023-09-11 |
2023-10-07 |
human |