| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Sophie Holtkamp, Diego Echevarría, István Adorján, Ágota Ádám, András Csilla. Early cellular and synaptic changes in dopaminoceptive forebrain regions of juvenile mice following gestational exposure to valproate. Frontiers in neuroanatomy. vol 17. 2023-08-21. PMID:37603782. |
we observed a surge of apoptosis on vpa treatment in nearly all investigated subpallial and pallial regions; with a non-significant trend of similar increase the nucleus accumbens (nac) at p7, the age at which the mt pathway reduction has been reported (also supplemented by current findings). |
2023-08-21 |
2023-09-07 |
mouse |
| Margaret P Schmill, Zoe Thompson, Daisy Lee, Laurence Haddadin, Shaarang Mitra, Raymond Ezzat, Samantha Shelton, Phillip Levin, Sogol Behnam, Kelly J Huffman, Theodore Garlan. Hippocampal, whole midbrain, red nucleus, and ventral tegmental area volumes are increased by selective breeding for high voluntary wheel-running behavior. Brain, behavior and evolution. 2023-08-21. PMID:37604130. |
neither linetype nor wheel access affected volumes of the substantia nigra (sn), ventral tegmental area (vta), nucleus accumbens (nac), ventral pallidum (vp) or basolateral amygdala (bla). |
2023-08-21 |
2023-09-07 |
mouse |
| Mohammad Akhoondian, Samira Rashtiani, Behrooz Khakpour Taleghani, Mohammad Rostampour, Adele Jafari, Kambiz Rohampou. Lateral habenula deep brain stimulation alleviates depression-like behaviors and reverses the oscillatory pattern in the nucleus accumbens in an animal model of depression. Brain research bulletin. 2023-08-20. PMID:37598800. |
after surgery and electrode placement in the lateral habenula (lhb), nucleus accumbens (nac), and prelimbic cortex (prl), the cms protocol was applied for 3 weeks to create depression-like models. |
2023-08-20 |
2023-09-07 |
rat |
| Veronika Kondev, Mustafa Najeed, Niharika Loomba, Jordan Brown, Danny G Winder, Brad A Grueter, Sachin Pate. Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 34. 2023-08-17. PMID:37590414. |
interneuron populations within the nucleus accumbens (nac) orchestrate excitatory-inhibitory balance, undergo experience-dependent plasticity, and gate-motivated behavior, all biobehavioral processes heavily modulated by endogenous cannabinoid (ecb) signaling. |
2023-08-17 |
2023-09-07 |
Not clear |
| Pingping Zhao, Xing Chen, Arash Bellafard, Avaneesh Murugesan, Jonathan Quan, Daniel Aharoni, Peyman Golshan. Accelerated social representational drift in the nucleus accumbens in a model of autism. bioRxiv : the preprint server for biology. 2023-08-14. PMID:37577515. |
how the nucleus accumbens (nac), as a key hub of reward circuitry, encodes social interaction and whether these representations are altered in asd remain poorly understood. |
2023-08-14 |
2023-08-16 |
Not clear |
| Azam Notaj, Amir Erfanparast, Esmaeal Tamaddonfard, Farhad Soltanalinejad-Taghiaba. Exogenous histamine and H 2 receptor activation and H 3 receptor inhibition in nucleus accumbens modulate formalin-induced orofacial nociception through opioid receptors. Behavioural pharmacology. 2023-08-14. PMID:37578392. |
it has been demonstrated that the nucleus accumbens (nac) plays an important role in modulation of nociception due to its extensive connections with different regions of the brain. |
2023-08-14 |
2023-08-16 |
rat |
| Enrica Montalban, Albert Giralt, Lieng Taing, Yuki Nakamura, Assunta Pelosi, Mallory Brown, Benoit de Pins, Emmanuel Valjent, Miquel Martin, Angus C Nairn, Paul Greengard, Marc Flajolet, Denis Hervé, Nicolas Gambardella, Jean-Pierre Roussarie, Jean-Antoine Giraul. Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin. Biological psychiatry. 2023-08-14. PMID:37579933. |
these effects involve the reward system and dopamine neurons, which modulate neurons in the nucleus accumbens (nac). |
2023-08-14 |
2023-09-07 |
Not clear |
| Huanhuan Wang, Yukie Yamahashi, Marcel Riedl, Mutsuki Amano, Kozo Kaibuch. The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569255. |
we have recently shown that the alzheimer's disease (ad) therapeutic drug donepezil activates the rac1-pak pathway in the nucleus accumbens (nac) for enhanced aversive learning. |
2023-08-12 |
2023-08-16 |
mouse |
| Hailei Yu, Boyang Wen, Yun Lu, Bing Xie, Feng Yu, Minglong Zhang, Chunling Ma, Bin Cong, Di Wen, Haitao B. The Role of circTmeff-1 in Morphine Addiction Memory of Mice. Cells. vol 12. issue 15. 2023-08-11. PMID:37566064. |
here, we trained mice on a conditional place preference (cpp) model and collected nucleus accumbens (nac) tissues from day 1 (t0) and day 8 (t1) for high-throughput rna sequencing. |
2023-08-11 |
2023-08-16 |
mouse |
| Yongsheng Zhu, Kejia Wang, Tengfei Ma, Yuanyuan Ji, Yin Lou, Xiaoyu Fu, Ye Lu, Yige Liu, Wei Dang, Qian Zhang, Fangyuan Yin, Kena Wang, Bing Yu, Hongbo Zhang, Jianghua Lai, Yunpeng Wan. Nucleus accumbens D1/D2 circuits control opioid withdrawal symptoms in mice. The Journal of clinical investigation. 2023-08-10. PMID:37561576. |
the nucleus accumbens (nac) is the most promising target for drug use disorder treatment. |
2023-08-10 |
2023-08-16 |
mouse |
| Munir Gunes Kutlu, Jennifer Tat, Brooke A Christensen, Jennifer E Zachry, Erin S Calipar. Dopamine release at the time of a predicted aversive outcome causally controls the trajectory and expression of conditioned behavior. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543945. |
dopamine release in the nucleus accumbens (nac) is causally linked to adaptive aversive learning, and its dysregulation is a core phenotype in anxiety and stress disorders. |
2023-08-06 |
2023-08-14 |
mouse |
| Haiyan Sun, Zhilin Li, Zhentong Qiu, Yu Shen, Qingchen Guo, Su-Wan Hu, Hai-Lei Ding, Shuming An, Jun-Li Ca. A common neuronal ensemble in nucleus accumbens regulates pain-like behaviour and sleep. Nature communications. vol 14. issue 1. 2023-08-05. PMID:37543693. |
here, we identify a dual-functional ensemble that regulates both pain-like behaviour induced by chronic constrictive injury or complete freund's adjuvant, and sleep wakefulness, in the nucleus accumbens (nac) in mice. |
2023-08-05 |
2023-08-14 |
mouse |
| Yiling Wang, Lirong Tang, Miao Wang, Guowei Wu, Weihua Li, Xuemei Wang, Jiani Wang, Zhenghan Yang, Xiaohong Li, Zhanjiang Li, Qian Chen, Peng Zhang, Zhenchang Wan. The role of functional and structural properties of the nucleus accumbens subregions in eating behavior regulation of bulimia nervosa. The International journal of eating disorders. 2023-08-02. PMID:37530570. |
although studies have demonstrated the involvement of the nucleus accumbens (nac) in the neurobiology of eating disorders, its alterations in bulimia nervosa (bn) remain largely unknown. |
2023-08-02 |
2023-08-14 |
Not clear |
| Giuseppe Tringali, Gianluca Lavanco, Valentina Castelli, Giuseppe Pizzolanti, Martin Kuchar, Diego Currò, Carla Cannizzaro, Anna Brancat. Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking adolescent rats. Focus on calcitonin gene-related peptide's brain levels. Phytotherapy research : PTR. 2023-08-01. PMID:37525534. |
adolescent male rats underwent the intermittent 20% alcohol two-bottle choice paradigm; at the binge day (bd) and the 24 h withdrawal day (wd), we assessed cgrp expression in medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, hypothalamus and brainstem; in addition, we evaluated sucrose preference, social motivation and drive, nociceptive response, and serum corticosterone levels. |
2023-08-01 |
2023-08-14 |
rat |
| Erika M Vitale, Adrianna Kirckof, Adam S Smit. Partner-seeking and limbic dopamine system are enhanced following social loss in male prairie voles (Microtus ochrogaster). Genes, brain, and behavior. 2023-07-31. PMID:37519035. |
furthermore, we examined dopamine (da) receptor mrna expression in the anterior insula cortex (aic), nucleus accumbens (nac), and anterior cingulate (acc), regions with higher activation in grieving humans. |
2023-07-31 |
2023-08-14 |
Not clear |
| Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yak. N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice. Translational psychiatry. vol 13. issue 1. 2023-07-31. PMID:37524707. |
we first measured the ecbs and ecb-ls levels in different brain reward system regions following chronic alcohol self-administration using lc-ms. we have found that following chronic intermittent alcohol consumption, n-oleoyl glycine (olgly) levels were significantly elevated in the prefrontal cortex (pfc), and n-oleoyl alanine (olala) was significantly elevated in the pfc, nucleus accumbens (nac) and ventral tegmental area (vta) in a region-specific manner. |
2023-07-31 |
2023-08-14 |
mouse |
| Marion Sourty, Md Taufiq Nasseef, Cédric Champagnol-Di Liberti, Mary Mondino, Vincent Noblet, Eric M Parise, Tamara Markovic, Caleb J Browne, Emmanuel Darcq, Eric J Nestler, Brigitte L Kieffe. Manipulating ΔFOSB in D1-type Medium Spiny Neurons of the nucleus accumbens reshapes whole brain functional connectivity. Biological psychiatry. 2023-07-30. PMID:37517704. |
the transcription factor, Δfosb, acting in the nucleus accumbens (nac), has been shown to control transcriptional and behavioral responses to opioids and other drugs of abuse. |
2023-07-30 |
2023-08-14 |
Not clear |
| Courtney S Wilkinson, Harrison L Blount, Marek Schwendt, Lori A Knacksted. Brain Monoamine Dysfunction in Response to Predator Scent Stress Accompanies Stress-Susceptibility in Female Rats. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509091. |
using a predator scent stress (pss) rodent model of ptsd, we sought to determine if stress-susceptible female rats show altered monoamine concentrations in brain regions associated with ptsd: the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and dorsal (dhipp) and ventral (vhipp) hippocampus. |
2023-07-29 |
2023-08-14 |
rat |
| Lauren Faget, Lucie Oriol, Wen-Chun Lee, Cody Sargent, Dhakshin Ramanathan, Thomas S Hnask. Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37502884. |
however, vp glut neurons evoked da in reward-associated ventromedial nucleus accumbens (nac), but reduced da in aversion-associated dorsomedial nac. |
2023-07-28 |
2023-08-14 |
human |
| Oyku Dinckol, Jennifer E Zachry, Munir Gunes Kutl. Nucleus accumbens core single cell ensembles bidirectionally respond to experienced versus observed aversive events. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37503203. |
in this study, we recorded single cell activity patterns of nucleus accumbens (nac) core neurons using in vivo optical imaging of calcium transients via miniature scopes. |
2023-07-28 |
2023-08-14 |
Not clear |