| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D W Self, L M Genova, B T Hope, W J Barnhart, J J Spencer, E J Nestle. Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 5. 1998-03-04. PMID:9465009. |
camp-dependent protein kinase (pka) in the nucleus accumbens (nac) has been implicated in cocaine addiction because (1) cocaine reinforcement is mediated by dopamine receptors that modulate camp formation, and (2) repeated exposure to cocaine upregulates the camp system in nac neurons. |
1998-03-04 |
2023-08-12 |
human |
| H C Hung, E H Le. MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways. Free radical biology & medicine. vol 24. issue 1. 1998-03-02. PMID:9436616. |
results revealed that mptp increased lipid peroxidation in the striatum (st) and decreased glutathione concentration in the substantia nigra (sn) without markedly affecting these measures in the nucleus accumbens (nac) and ventral tegmental area (vta). |
1998-03-02 |
2023-08-12 |
mouse |
| H Takahashi, Y Takada, N Nagai, T Urano, A Takad. Effects of nicotine and footshock stress on dopamine release in the striatum and nucleus accumbens. Brain research bulletin. vol 45. issue 2. 1998-02-26. PMID:9443833. |
we have used a microdialysis technique to analyze the effects of nicotine administration on the release of dopamine in the striatum and the nucleus accumbens (nac) in rats under footshock stress. |
1998-02-26 |
2023-08-12 |
rat |
| H Ozer, A C Ekinci, M S Star. Dopamine D1- and D2-dependent catalepsy in the rat requires functional NMDA receptors in the corpus striatum, nucleus accumbens and substantia nigra pars reticulata. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449412. |
mk-801, 0.2 mg/kg i.p., strongly opposed the cataleptogenic actions of sch 23390 and raclopride administered systemically (1 and 3 mg/kg i.p., respectively), or directly into the corpus striatum (cs) or nucleus accumbens (nac; 1 and 10 microg, respectively). |
1998-02-24 |
2023-08-12 |
rat |
| I Weiner, J Feldo. The switching model of latent inhibition: an update of neural substrates. Behavioural brain research. vol 88. issue 1. 1998-02-04. PMID:9401704. |
on the basis of these findings, the switching model of li proposed that li depends on the subicular input to the nucleus accumbens (nac). |
1998-02-04 |
2023-08-12 |
Not clear |
| G Tanda, F E Pontieri, R Frau, G Di Chiar. Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine. The European journal of neuroscience. vol 9. issue 10. 1998-02-04. PMID:9421168. |
to this end, changes of extracellular da and na in the pfcx and of extracellular da in the nucleus accumbens (nac) were measured following the administration of amphetamine and cocaine, which are known to bind to both da and na carriers, or gbr 12909, a selective da carrier blocker. |
1998-02-04 |
2023-08-12 |
rat |
| R J Moore, S L Vinsant, M A Nader, L J Porrino, D P Friedma. Effect of cocaine self-administration on striatal dopamine D1 receptors in rhesus monkeys. Synapse (New York, N.Y.). vol 28. issue 1. 1998-01-20. PMID:9414012. |
because the release of dopamine in the nucleus accumbens (nac) has been implicated in mediating the reinforcing effects of cocaine, changes in dopamine function can have profound effects on drug-seeking and drug-taking behavior. |
1998-01-20 |
2023-08-12 |
monkey |
| M Yoshida, H Yokoo, K Nakahara, M Tomita, N Hamada, M Ishikawa, J Hatakeyama, M Tanaka, I Nagats. Local muscimol disinhibits mesolimbic dopaminergic activity as examined by brain microdialysis and Fos immunohistochemistry. Brain research. vol 767. issue 2. 1998-01-15. PMID:9367268. |
infusion of muscimol (5 x 10[-5] m, 60 min) into the nucleus accumbens (nac) through a dialysis membrane caused a significant increase in extracellular dopamine (da) and its metabolite, 3,4-dihydroxyphenylacetic acid (dopac). |
1998-01-15 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, K Chergui, P Grillner, T H Svensso. Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 3. 1998-01-08. PMID:9272482. |
in the present study, expression of the immediate early gene protein products fos and jun-b within the dorsolateral striatum, the core and shell of the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the ventrolateral orbital cortex was examined. |
1998-01-08 |
2023-08-12 |
rat |
| H Mann, B Ladenheim, H Hirata, T H Moran, J L Cade. Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain research. vol 769. issue 2. 1997-12-23. PMID:9374204. |
meth caused significant dose-dependent decreases of dopamine (da) and da transporters (dat) in the striatum and the nucleus accumbens (nac) of both wild-type and knockout mice. |
1997-12-23 |
2023-08-12 |
mouse |
| B H Guevara, I S Hoffmann, L X Cubedd. Ventral and dorsal striatal cholinergic neurons have different sensitivities to kainic acid. Neurochemistry international. vol 31. issue 5. 1997-12-22. PMID:9364458. |
direct stereotaxic injections of high-dose ka (4 micrograms/2 microliters) into specific brain regions, reduced cat in caudate putamen (cp) by 91 +/- 1%, in nucleus accumbens (nac) by 71 +/- 6%, but cat in the olfactory tubercle (ot) was not affected by ka. |
1997-12-22 |
2023-08-12 |
rat |
| B Bontempi, F R Shar. Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334431. |
to characterize how systemic morphine induces fos protein in dorsomedial striatum and nucleus accumbens (nac), we examined the role of receptors in striatum, substantia nigra (sn), and ventral tegmental area (vta). |
1997-11-20 |
2023-08-12 |
rat |
| U Datta, P A Noailles, M Kraft, Y Zhang, J A Angul. Concurrent elevation of the levels of expression of striatal preproenkephalin and preprodynorphin mRNA in the rat brain by chronic treatment with caffeine. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280160. |
in contrast to ppe mrna, ppd mrna was increased +117% above control in the nucleus accumbens (nac) at 20 mg/kg of caffeine. |
1997-10-23 |
2023-08-12 |
rat |
| S A Josselyn, A De Cristofaro, F J Vaccarin. Evidence for CCK(A) receptor involvement in the acquisition of conditioned activity produced by cocaine in rats. Brain research. vol 763. issue 1. 1997-10-17. PMID:9272833. |
cholecystokinin (cck) is co-localized with dopamine (da) in the nucleus accumbens (nac) where evidence suggests that cck(b) receptor-mediated mechanisms inhibit, while cck(a) receptor-mediated mechanisms facilitate, da function. |
1997-10-17 |
2023-08-12 |
rat |
| S M Nicola, R C Malenk. Dopamine depresses excitatory and inhibitory synaptic transmission by distinct mechanisms in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221769. |
the release of dopamine (da) in the nucleus accumbens (nac) is thought to be critical for mediating natural rewards as well as for the reinforcing actions of drugs of abuse. |
1997-10-03 |
2023-08-12 |
Not clear |
| S J Cragg, S A Greenfiel. Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221772. |
furthermore, we compared d2 regulation of somatodendritic release with the more familiar axon terminal release in caudate putamen (cpu) and nucleus accumbens (nac). |
1997-10-03 |
2023-08-12 |
Not clear |
| W Dyr, W Kostowsk. Effects of 5-HT3 receptor agonists on voluntary ethanol intake in rats maintained on a limited access procedure. Alcohol and alcoholism (Oxford, Oxfordshire). vol 32. issue 4. 1997-10-03. PMID:9269853. |
and into the nucleus accumbens (nac) on etoh intake in wistar rats with high etoh preference. |
1997-10-03 |
2023-08-12 |
rat |
| M J Nirenberg, J Chan, A Pohorille, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 18. 1997-10-03. PMID:9278525. |
these functions are known to differ in the limbic-associated shell and motor-associated core compartments of the nucleus accumbens (nac). |
1997-10-03 |
2023-08-12 |
Not clear |
| T E Sipes, M A Geye. DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum. Brain research. vol 761. issue 1. 1997-10-01. PMID:9247071. |
5-ht2a receptors are densely localized in the nucleus accumbens (nac) and the ventral pallidum (vp), areas known to be important components of neural circuitry that mediates the ventral forebrain modulation of ppi. |
1997-10-01 |
2023-08-12 |
rat |
| J Balthazart, P Absil, C Viglietti-Panzica, G C Panzic. Vasotocinergic innervation of areas containing aromatase-immunoreactive cells in the quail forebrain. Journal of neurobiology. vol 33. issue 1. 1997-08-27. PMID:9212069. |
in the male quail forebrain, aromatase-immunoreactive (aro-ir) elements are clustered within the sexually dimorphic medial preoptic nucleus (pom), nucleus striae terminalis (nst), nucleus accumbens (nac), and ventromedial and tuberal hypothalamus. |
1997-08-27 |
2023-08-12 |
Not clear |