| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M M Marcus, G G Nomikos, A Malmerfelt, O Zachrisson, N Lindefors, T H Svensso. Effect of chronic antipsychotic drug treatment on preprosomatostatin and preprotachykinin A mRNA levels in the medial prefrontal cortex, the nucleus accumbens and the caudate putamen of the rat. Brain research. Molecular brain research. vol 45. issue 2. 1997-08-07. PMID:9149102. |
in situ hybridization histochemistry was used to study the expression of preprosomatostatin (ppsom) and preprotachykinin a (ppt-a) mrna in the medial prefrontal cortex (mpfc), the nucleus accumbens (nac) and the caudate putamen (cp) of the rat after chronic (21 days) treatment with the classical antipsychotic drug haloperidol (1 mg/kg i.p. |
1997-08-07 |
2023-08-12 |
rat |
| W Hauber, M Koc. Adenosine A2a receptors in the nucleus accumbens modulate prepulse inhibition of the startle response. Neuroreport. vol 8. issue 6. 1997-08-07. PMID:9172165. |
microinfusion of the selective adenosine a2a-recceptor agonist cgs21680 (0.05 microgram in 1.0 microliter per side) into the nucleus accumbens (nac), had no significant effect in animals with systemic vehicle pretreatment, but significantly reversed the disruption of ppi in rats pretreated with apo. |
1997-08-07 |
2023-08-12 |
rat |
| W Lu, H Chen, C J Xue, M E Wol. Repeated amphetamine administration alters the expression of mRNA for AMPA receptor subunits in rat nucleus accumbens and prefrontal cortex. Synapse (New York, N.Y.). vol 26. issue 3. 1997-08-01. PMID:9183816. |
recent evidence suggests that behavioral sensitization to amphetamine is associated with alterations in excitatory amino acid (eaa) transmission in perikarya (ventral tegmental area) and terminal regions (nucleus accumbens [nac]) of the mesoaccumbens dopamine system. |
1997-08-01 |
2023-08-12 |
rat |
| Y Zhang, K Landas, H Mueller, J A Angul. Progressive augmentation of striatal and accumbal preprotachykinin mRNA levels by chronic treatment with methamphetamine and effect of concurrent administration of the N-methyl-D-aspartate receptor antagonist MK-801. Neuropharmacology. vol 36. issue 3. 1997-07-24. PMID:9175611. |
we have assessed the time course of repeated administration of methamphetamine (meth; 4 mg/kg) and withdrawal on the levels of preprotachykinin (ppt) and preproenkephalin (ppe) mrna abundance in the caudate-putamen (cpu) and nucleus accumbens (nac) of the rat brain by in situ hybridization histochemistry. |
1997-07-24 |
2023-08-12 |
rat |
| J C Shyu, C Y Chu, S L Duh, J Y Liu, C L Chan. Nucleus accumbens dopaminergic mediation of protection against gastric mucosal ulcerations by cold-restraint stress in the male hyperprolactinemic rats. The Chinese journal of physiology. vol 40. issue 1. 1997-07-21. PMID:9170554. |
da and its metabolites, dopac content in nucleus accumbens (nac) area of brain were assayed by hplc with electrochemical detection. |
1997-07-21 |
2023-08-12 |
rat |
| J Y Chang, L Zhang, P H Janak, D J Woodwar. Neuronal responses in prefrontal cortex and nucleus accumbens during heroin self-administration in freely moving rats. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134954. |
chronic multi-channel single unit recordings of neuronal responses in prefrontal cortex (pfc) and nucleus accumbens (nac) were made in 9 male sprague dawley rats to determine patterns of neuronal activity during heroin self-administration. |
1997-07-15 |
2023-08-12 |
rat |
| D F Fiorino, A Coury, A G Phillip. Dynamic changes in nucleus accumbens dopamine efflux during the Coolidge effect in male rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 12. 1997-06-30. PMID:9169543. |
given the role of the mesolimbic dopamine (da) system in the initiation and maintenance of motivated behavior, microdialysis was used to monitor nucleus accumbens (nac) da transmission during copulation, sexual satiety, and the reinitiation of sexual behavior. |
1997-06-30 |
2023-08-12 |
rat |
| W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
animals were sacrificed and the substantia nigra/ventral tegmental area (sn/vta) and nucleus accumbens (nac) were dissected for the determination of dopamine concentrations using hplc. |
1997-06-19 |
2023-08-12 |
rat |
| A Her. Endogenous opioid systems and alcohol addiction. Psychopharmacology. vol 129. issue 2. 1997-06-16. PMID:9040115. |
the rewarding (reinforcing) properties of mu- and delta-receptor ligands are brought by activation of the mesolimbic dopamine system which ascends from the ventral tegmentum of the midbrain (vta) to rostral structures; of these, the nucleus accumbens (nac) is of particular importance in drug addiction. |
1997-06-16 |
2023-08-12 |
Not clear |
| M Nisell, M Marcus, G G Nomikos, T H Svensso. Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 1. 1997-06-16. PMID:9085189. |
like several drugs of abuse, nicotine increase dopamine (da) release in the nucleus accumbens (nac). |
1997-06-16 |
2023-08-12 |
rat |
| R P Hammer, Y Egilmez, M W Emmett-Oglesb. Neural mechanisms of tolerance to the effects of cocaine. Behavioural brain research. vol 84. issue 1-2. 1997-06-13. PMID:9079787. |
the mechanism underlying this effect may involve an absolute or relative attenuation of dopamine response to cocaine challenge after frequent or repeated treatment in the nucleus accumbens (nac). |
1997-06-13 |
2023-08-12 |
human |
| J J Byrnes, L J Wallac. Amphetamine-induced sensitization and release of dopamine in slices from the ventral tegmental area of rats is enhanced following administration of cholera toxin into the ventral tegmental area. Neuroscience letters. vol 223. issue 1. 1997-06-12. PMID:9058419. |
experiments were conducted to determine whether this phenomenon is associated with altered dopamine release from the vta and nucleus accumbens (nac). |
1997-06-12 |
2023-08-12 |
rat |
| R Kuczenski, D S Sega. An escalating dose/multiple high-dose binge pattern of amphetamine administration results in differential changes in the extracellular dopamine response profiles in caudate-putamen and nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 11. 1997-06-10. PMID:9151761. |
because of the involvement of mesolimbic and mesostriatal dopamine (da) pathways in locomotion and stereotypy, respectively, we hypothesized that a persistent shift in the relative magnitude of caudate-putamen (cp) and nucleus accumbens (nac) da transmission may contribute to this altered behavioral profile. |
1997-06-10 |
2023-08-12 |
Not clear |
| K Ikemoto, K Kitahama, T Maeda, K Sato. The distribution of noradrenaline, serotonin and gamma-aminobutyric acid in the monkey nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 20. issue 8. 1997-06-05. PMID:9004346. |
the recent histochemical studies have shown that the primate nucleus accumbens (nac) can be subdivided into at least three subdivisions, the medial, ventral and dorsolateral subdivisions. |
1997-06-05 |
2023-08-12 |
monkey |
| S A Josselyn, F J Vaccarin. Acquisition of conditioned reward blocked by intra-accumbens infusion of PD-140548, a CCKA receptor antagonist. Pharmacology, biochemistry, and behavior. vol 55. issue 3. 1997-05-08. PMID:8951986. |
cholecystokinin (cck) is an endogenous peptide that is colocalized with dopamine (da) in some mesolimbic neurons projecting to the nucleus accumbens (nac). |
1997-05-08 |
2023-08-12 |
Not clear |
| M A Parada, L Hernandez, M Puig de Parada, P Rada, E Murz. Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum. The Journal of pharmacology and experimental therapeutics. vol 281. issue 1. 1997-05-02. PMID:9103547. |
clozapine [0 (n = 6), 5 (n = 5), 10 (n = 5), 20 (n = 9) and 40 (n = 5) mg/kg] on acetylcholine (ach) release in the prefrontal cortex (pfc), nucleus accumbens (nac) and striatum (str) were studied by simultaneous triple microdialysis in freely moving rats. |
1997-05-02 |
2023-08-12 |
human |
| P I Johnson, T C Napie. Contribution of the nucleus accumbens to cocaine-induced responses of ventral pallidal neurons. Synapse (New York, N.Y.). vol 22. issue 3. 1997-04-29. PMID:9132994. |
given the responsiveness of vp neurons to cocaine, the extensive innervation of the vp by the nucleus accumbens (nac), and the importance of the nac in regulating cocaine-induced effects, it is likely that nac activity may affect vp responses to cocaine. |
1997-04-29 |
2023-08-12 |
rat |
| I Panocka, R Ciccocioppo, C Polidori, S Romagnoli, R Froldi, M Mass. Possible mechanism of action for the attenuation of ethanol intake induced by ritanserin in rats. Psychopharmacology. vol 128. issue 2. 1997-04-10. PMID:8956379. |
the 5-ht2 receptor antagonist, ritanserin, reduces alcohol intake in rats and the nucleus accumbens (nac) has been proposed as a site of action for the drug. |
1997-04-10 |
2023-08-12 |
rat |
| J Ma, S M Brudzynski, L W Leun. Involvement of the nucleus accumbens-ventral pallidal pathway in postictal behavior induced by a hippocampal afterdischarge in rats. Brain research. vol 739. issue 1-2. 1997-04-01. PMID:8955921. |
the hypothesis that postictal motor behaviors induced by a hippocampal afterdischarge (ad) are mediated by a pathway through the nucleus accumbens (nac) and ventral pallidum (vp) was evaluated in freely moving rats. |
1997-04-01 |
2023-08-12 |
rat |
| R N Clark, C R Ashby, S L Dewey, P V Ramachandran, R E Strecke. Effect of acute and chronic fluoxetine on extracellular dopamine levels in the caudate-putamen and nucleus accumbens of rat. Synapse (New York, N.Y.). vol 23. issue 3. 1997-03-24. PMID:8807740. |
recent studies indicate that an increase in serotonergic (5-ht) activity in the nucleus accumbens (nac) produces an increase in dopamine (da) release, providing a possible mechanism for the involvement of da in the therapeutic action of selective serotonin reuptake inhibitor (ssri) antidepressants. |
1997-03-24 |
2023-08-12 |
rat |