| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Kuroki, H Y Meltzer, J Ichikaw. Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 288. issue 2. 1999-02-22. PMID:9918588. |
the present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (da) levels in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), using in vivo microdialysis with dual probe implantation in awake, freely moving rats. |
1999-02-22 |
2023-08-12 |
rat |
| N Thiriet, N Humblot, C Burgun, D Aunis, J Zwille. Cocaine and fluoxetine induce the expression of the hVH-5 gene encoding a MAP kinase phosphatase. Brain research. Molecular brain research. vol 62. issue 2. 1999-02-18. PMID:9813294. |
injection of cocaine, amphetamine and caffeine induced hvh-5 mrna expression within 40 min in the nucleus accumbens (nac), caudate putamen, frontal cortex and hippocampus, with a maximal effect in the nac. |
1999-02-18 |
2023-08-12 |
rat |
| I Weiner, J Feldon, R Tarrasch, I Hairston, D Joe. Fimbria-fornix cut affects spontaneous activity, two-way avoidance and delayed non matching to sample, but not latent inhibition. Behavioural brain research. vol 96. issue 1-2. 1999-02-05. PMID:9821543. |
based on evidence pointing to the involvement of the hippocampus and the nucleus accumbens (nac) in li disruption, it has been proposed that li depends on the integrity of the subicular input to the nac. |
1999-02-05 |
2023-08-12 |
Not clear |
| S E Hemby, C Co, S I Dworkin, J E Smit. Synergistic elevations in nucleus accumbens extracellular dopamine concentrations during self-administration of cocaine/heroin combinations (Speedball) in rats. The Journal of pharmacology and experimental therapeutics. vol 288. issue 1. 1999-02-05. PMID:9862781. |
several studies suggest dopaminergic innervations of the nucleus accumbens (nac) have a central role in the brain processes underlying drug reinforcement. |
1999-02-05 |
2023-08-12 |
rat |
| D F Fiorino, A G Phillip. Facilitation of sexual behavior and enhanced dopamine efflux in the nucleus accumbens of male rats after D-amphetamine-induced behavioral sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 1. 1999-02-05. PMID:9870973. |
the present microdialysis study investigated the effect of d-amphetamine-induced sensitization on dopamine (da) efflux in the nucleus accumbens (nac) of male rats during sexual behavior. |
1999-02-05 |
2023-08-12 |
rat |
| R Nadal, A M Chappell, H H Samso. Effects of nicotine and mecamylamine microinjections into the nucleus accumbens on ethanol and sucrose self-administration. Alcoholism, clinical and experimental research. vol 22. issue 6. 1999-01-04. PMID:9756032. |
although the mesolimbic dopamine systems are known to be involved in the reinforcing effects of etoh, the role of nicotinic receptors within the nucleus accumbens (nac) in etoh reinforcement has not been studied. |
1999-01-04 |
2023-08-12 |
rat |
| C A Heidbreder, S Schenk, B Partridge, T S Shippenber. Increased responsiveness of mesolimbic and mesostriatal dopamine neurons to cocaine following repeated administration of a selective kappa-opioid receptor agonist. Synapse (New York, N.Y.). vol 30. issue 3. 1998-12-28. PMID:9776129. |
accordingly, the present microdialysis study characterized the effects of prior, repeated administration of the selective kappa-opioid receptor agonist u69593 on basal and cocaine-evoked da levels within the nucleus accumbens (nac) and caudate putamen (cpu). |
1998-12-28 |
2023-08-12 |
rat |
| G Panagis, A Kastellakis, C Spyrak. Involvement of the ventral tegmental area opiate receptors in self-stimulation elicited from the ventral pallidum. Psychopharmacology. vol 139. issue 3. 1998-12-28. PMID:9784077. |
three additional groups were implanted with guide cannulae in the nucleus accumbens (nac), the ventral tegmental area (vta) or dorsally to the vta and received microinjections of morphine (vehicle: 1.25; 2.50; 5.0; 10.0 microg/0.5 microl per side). |
1998-12-28 |
2023-08-12 |
rat |
| R C Huang, J Y Li. Voltage- and use-dependent inhibition by amphetamine of field potentials and Na+ current in rat nucleus accumbens neurons. Neuroscience letters. vol 252. issue 1. 1998-11-25. PMID:9756360. |
here we demonstrate direct amph inhibition of field potentials and na+ currents in rat nucleus accumbens (nac) neurons. |
1998-11-25 |
2023-08-12 |
rat |
| F I Tarazi, E C Tomasini, R J Baldessarin. Postnatal development of dopamine D4-like receptors in rat forebrain regions: comparison with D2-like receptors. Brain research. Developmental brain research. vol 110. issue 2. 1998-11-17. PMID:9748595. |
development of dopamine d4-like receptors in rat caudate-putamen (cpu), nucleus accumbens (nac), frontal cortex, hippocampus, and entorhinal cortex was assessed at seven points between postnatal days 7 and 60 by computed in vitro receptor autoradiography, and compared with dopamine (da) d2-like receptors. |
1998-11-17 |
2023-08-12 |
rat |
| D A Baker, R A Fuchs, S E Specio, T V Khroyan, J L Neisewande. Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723788. |
after behavioral testing was completed, animals were injected with their respective dose of sch-23390 into the nucleus accumbens (nac), followed by a systemic injection of the irreversible antagonist n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq). |
1998-11-16 |
2023-08-12 |
rat |
| J L Neisewander, R A Fuchs, L E O'Dell, T V Khroya. Effects of SCH-23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723789. |
in experiment 2, rats received coinfusion of sch-23390 (0-1 microg/side) and cocaine (0 or 100 microg/side) into the nucleus accumbens (nac). |
1998-11-16 |
2023-08-12 |
rat |
| F I Tarazi, A Campbell, S K Yeghiayan, R J Baldessarin. Localization of ionotropic glutamate receptors in caudate-putamen and nucleus accumbens septi of rat brain: comparison of NMDA, AMPA, and kainate receptors. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723793. |
changes in binding of selective radioligands at nmda ([3h]mk-801), ampa ([3h]cnqx), and kainate ([3h]kainic acid) glutamate (glu) ionotropic receptors in rat caudate-putamen (cpu) and nucleus accumbens (nac) were examined by quantitative autoradiography following: 1) unilateral surgical ablation of frontal cerebral cortex to remove descending corticostriatal glu projections, 2) unilateral injection of kainic acid (ka) into cpu or nac to degenerate local intrinsic neurons, or 3) unilateral injections of 6-hydroxydopamine (6-oh-da) into substantia nigra to degenerate ascending nigrostriatal dopamine (da) projections. |
1998-11-16 |
2023-08-12 |
rat |
| T A Patterson, M D Brot, A Zavosh, J O Schenk, P Szot, D P Figlewic. Food deprivation decreases mRNA and activity of the rat dopamine transporter. Neuroendocrinology. vol 68. issue 1. 1998-10-23. PMID:9695934. |
binding of a specific high-affinity dat ligand (125i-rti-121) to membranes from brain regions of fasted or free-feeding rats provided an estimate of dat protein, which was unchanged in both of the major terminal projection fields, the striatum and nucleus accumbens (nac). |
1998-10-23 |
2023-08-12 |
rat |
| F I Tarazi, S K Yeghiayan, J L Neumeyer, R J Baldessarin. Medial prefrontal cortical D2 and striatolimbic D4 dopamine receptors: common targets for typical and atypical antipsychotic drugs. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 4. 1998-10-13. PMID:9682281. |
d2 receptors in caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (ot) were significantly increased by long-term treatment with fluphenazine, but not with clozapine or s[+]-npa. |
1998-10-13 |
2023-08-12 |
Not clear |
| O Manzoni, D Pujalte, J Williams, J Bockaer. Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 19. 1998-10-09. PMID:9742166. |
the nucleus accumbens (nac) is a site mediating the rewarding properties of drugs of abuse, such as cocaine, amphetamine, opiates, nicotine, and alcohol (wise and bozarth, 1987; koob, 1992; samson andharris, 1992; woolverton and johnson, 1992; self and nestler, 1995; pontieri et al., 1996). |
1998-10-09 |
2023-08-12 |
Not clear |
| T Watanabe, K Morimoto, M Nakamura, H Suwak. Modification of behavioral responses induced by electrical stimulation of the ventral tegmental area in rats. Behavioural brain research. vol 93. issue 1-2. 1998-09-24. PMID:9659994. |
similar responses were obtained when the nucleus accumbens (nac) or prefrontal cortex (pfc) were stimulated. |
1998-09-24 |
2023-08-12 |
rat |
| C Heidbreder, J Feldo. Amphetamine-induced neurochemical and locomotor responses are expressed differentially across the anteroposterior axis of the core and shell subterritories of the nucleus accumbens. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661249. |
the administration of psychostimulants increases dopamine (da) release within the nucleus accumbens (nac), a terminal projection site of mesolimbic da neurons, originating in the ventral tegmental area (vta). |
1998-09-24 |
2023-08-12 |
Not clear |
| B D Kretschmer, M Koc. The ventral pallidum mediates disruption of prepulse inhibition of the acoustic startle response induced by dopamine agonists, but not by NMDA antagonists. Brain research. vol 798. issue 1-2. 1998-09-11. PMID:9666129. |
the neuronal circuitry which regulates ppi consists of cortico-limbic brain structures where the nucleus accumbens (nac) plays a key role. |
1998-09-11 |
2023-08-12 |
rat |
| D Wei, I M Maisonneuve, M E Kuehne, S D Glic. Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats. Brain research. vol 800. issue 2. 1998-09-04. PMID:9685673. |
in vivo microdialysis and hplc (microbore) were used to determine acute changes in extracellular serotonin levels in nucleus accumbens (nac) and striatum (str) after both i.p. |
1998-09-04 |
2023-08-12 |
rat |