| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B A Morrow, R H Rot. Serotonergic lesions alter cocaine-induced locomotor behavior and stress-activation of the mesocorticolimbic dopamine system. Synapse (New York, N.Y.). vol 23. issue 3. 1997-03-24. PMID:8807745. |
5,7-dihydroxytryptamine lesions of the dorsal raphe resulted in a substantial loss of serotonin in the medial prefrontal cortex (about 75%) and the nucleus accumbens (about 50%), while no change in da levels or da metabolism were noted in either region at 12 days postlesion. |
1997-03-24 |
2023-08-12 |
rat |
| P Hertel, G G Nomikos, M Iurlo, T H Svensso. Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. Psychopharmacology. vol 124. issue 1-2. 1997-01-29. PMID:8935802. |
the nucleus accumbens (nac), the medial prefrontal cortex (mpc) and the lateral striatum (str). |
1997-01-29 |
2023-08-12 |
rat |
| B A Horger, J D Elsworth, R H Rot. Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966. Journal of neurochemistry. vol 66. issue 5. 1997-01-14. PMID:8780023. |
systemic administration of the anxiogenic benzodiazepine inverse agonist fg 7142 has been shown to increase selectively dopamine utilization in the medial prefrontal cortex and the shell, but not core, subregion of the nucleus accumbens. |
1997-01-14 |
2023-08-12 |
human |
| B A Horger, J D Elsworth, R H Rot. Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966. Journal of neurochemistry. vol 66. issue 5. 1997-01-14. PMID:8780023. |
(+)-ha 966 administration blocked fg 7142-induced increased dopamine utilization in both the medial prefrontal cortex and the shell subdivision of the nucleus accumbens. |
1997-01-14 |
2023-08-12 |
human |
| J N Carlson, K E Visker, D M Nielsen, R W Keller, S D Glic. Chronic antidepressant drug treatment reduces turning behavior and increases dopamine levels in the medial prefrontal cortex. Brain research. vol 707. issue 1. 1996-12-13. PMID:8866721. |
the effects of chronic administration of the antidepressant drugs desipramine, nortryptiline and paroxetine (par) (10 mg/kg/day, 21 days) on changes in turning (circling) behavior and on norepinephrine (ne), dopamine (da) and serotonin and their metabolites 3,4-dihydroxyphenylacetic acid and 5-hydroxyindole acetic acid (5-hiaa) in the medial prefrontal cortex (pfc), nucleus accumbens and striatum were evaluated in rats. |
1996-12-13 |
2023-08-12 |
rat |
| V Bassareo, G Tanda, P Petromilli, C Giua, G Di Chiar. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739543. |
non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. |
1996-11-25 |
2023-08-12 |
rat |
| V Bassareo, G Tanda, P Petromilli, C Giua, G Di Chiar. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739543. |
in rats vertically implanted with concentric dialysis probes in the medial prefrontal cortex and in the medial nucleus accumbens, morphine, ethanol and nicotine failed to modify extracellular dopamine in the medial prefrontal cortex at doses that were fully effective in raising extracellular dopamine in the nucleus accumbens. |
1996-11-25 |
2023-08-12 |
rat |
| V Bassareo, G Tanda, P Petromilli, C Giua, G Di Chiar. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739543. |
conversely, the aversive/anxiogenic drugs picrotoxin, pentylenetetrazol and fg 7142, administered at subconvulsant doses, increased extracellular dopamine in the medial prefrontal cortex but failed to do so in the nucleus accumbens. |
1996-11-25 |
2023-08-12 |
rat |
| V Bassareo, G Tanda, G Di Chiar. Increase of extracellular dopamine in the medial prefrontal cortex during spontaneous and naloxone-precipitated opiate abstinence. Psychopharmacology. vol 122. issue 2. 1996-10-24. PMID:8848538. |
the results show that dopamine neurotransmission in the medial prefrontal cortex responds to opiate withdrawal in a manner opposite to dopamine transmission in the nucleus accumbens and indicate that the dopamine system is affected by abstinence in a topographically specific manner, consistent with a different functional role of mesocortical as compared to mesolimbic dopamine systems. |
1996-10-24 |
2023-08-12 |
rat |
| H L Andersen, I C Kilpatric. Prevention by (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin of both catalepsy and the rises in rat striatal dopamine metabolism caused by haloperidol. British journal of pharmacology. vol 118. issue 2. 1996-10-16. PMID:8735647. |
haloperidol significantly increased the dopac (by 2 to 4 fold) and hva (by 3 to 7 fold) contents of the caudate-putamen, nucleus accumbens and medial prefrontal cortex. |
1996-10-16 |
2023-08-12 |
rat |
| B A Morrow, J D Elsworth, R H Rot. Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning. Synapse (New York, N.Y.). vol 22. issue 2. 1996-09-26. PMID:8787125. |
rats were conditioned to fear a tone by pairing it with footshock, so that when challenged with the tone alone, rats responded with immobility, defecation, and elevated dopamine metabolism in the medial prefrontal cortex and nucleus accumbens. |
1996-09-26 |
2023-08-12 |
rat |
| W H Pan, J C Sung, S M Fu. Locally application of amphetamine into the ventral tegmental area enhances dopamine release in the nucleus accumbens and the medial prefrontal cortex through noradrenergic neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768724. |
locally application of amphetamine into the ventral tegmental area enhances dopamine release in the nucleus accumbens and the medial prefrontal cortex through noradrenergic neurotransmission. |
1996-09-18 |
2023-08-12 |
rat |
| W H Pan, J C Sung, S M Fu. Locally application of amphetamine into the ventral tegmental area enhances dopamine release in the nucleus accumbens and the medial prefrontal cortex through noradrenergic neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 278. issue 2. 1996-09-18. PMID:8768724. |
the effects and mechanisms of locally applied d-amphetamine (amph) into the ventral tegmental area (vta) on extracellular dopamine (da) concentrations in both the nucleus accumbens (n acc) and the medial prefrontal cortex (mpfc) were investigated. |
1996-09-18 |
2023-08-12 |
rat |
| R A Radcliffe, V G Erwi. Alterations in locomotor activity after microinjections of GBR-12909, selective dopamine antagonists or neurotensin into the medial prefrontal cortex. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667212. |
it has been postulated that increased dopamine (da) activity in the medial prefrontal cortex (mpfc) exerts an inhibitory influence over da release in the nucleus accumbens and, thus, also over locomotor activity. |
1996-08-06 |
2023-08-12 |
mouse |
| C J Schmidt, G M Fadaye. Regional effects of MK-801 on dopamine release: effects of competitive NMDA or 5-HT2A receptor blockade. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667221. |
mk-801 stimulated dopamine release in both the medial prefrontal cortex and the nucleus accumbens but tended to decrease release in the striatum. |
1996-08-06 |
2023-08-12 |
rat |
| B A Morrow, J R Taylor, R H Rot. Prior exposure to cocaine diminishes behavioral and biochemical responses to aversive conditioning: reversal by glycine/N-methyl-D-aspartate antagonist co-treatment. Neuroscience. vol 69. issue 1. 1996-07-08. PMID:8637621. |
additionally, the elevated metabolic activity of dopamine in the medial prefrontal cortex, nucleus accumbens and ventral tegmental area associated with aversive conditioning was diminished in rats pre-exposed to cocaine. |
1996-07-08 |
2023-08-12 |
rat |
| T L Thompson, R L Mos. In vivo stimulated dopamine release in the nucleus accumbens: modulation by the prefrontal cortex. Brain research. vol 686. issue 1. 1995-11-28. PMID:7583276. |
in vivo voltammetry was used to measure stimulated dopamine (da) release in the nucleus accumbens following 6-hydroxydopamine (6-ohda) lesions of the medial prefrontal cortex (pfc). |
1995-11-28 |
2023-08-12 |
Not clear |
| B A Horger, J D Elsworth, R H Rot. Selective increase in dopamine utilization in the shell subdivision of the nucleus accumbens by the benzodiazepine inverse agonist FG 7142. Journal of neurochemistry. vol 65. issue 2. 1995-08-24. PMID:7616234. |
consistent with previous reports, fg 7142 administration increased dopamine utilization in the medial prefrontal cortex but not the whole nucleus accumbens. |
1995-08-24 |
2023-08-12 |
rat |
| N Guo, M A Klitenick, C S Tham, H C Fibige. Receptor mechanisms mediating clozapine-induced c-fos expression in the forebrain. Neuroscience. vol 65. issue 3. 1995-08-17. PMID:7609873. |
quinpirole produced a small but significant decrease in clozapine-induced c-fos expression in the medial prefrontal cortex, had larger effects in the lateral septum, and blocked clozapine's actions in the nucleus accumbens and major island of calleja. |
1995-08-17 |
2023-08-12 |
rat |
| W A Cass, G A Gerhard. In vivo assessment of dopamine uptake in rat medial prefrontal cortex: comparison with dorsal striatum and nucleus accumbens. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790861. |
in vivo assessment of dopamine uptake in rat medial prefrontal cortex: comparison with dorsal striatum and nucleus accumbens. |
1995-07-26 |
2023-08-12 |
rat |