| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Moghadda. Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. Journal of neurochemistry. vol 60. issue 5. 1993-05-18. PMID:8097232. |
the technique of intracerebral microdialysis was used to assess the effect of stress on the extracellular concentrations of excitatory amino acids, glutamate and aspartate, in the rat medial prefrontal cortex, hippocampus, striatum, and nucleus accumbens. |
1993-05-18 |
2023-08-12 |
rat |
| G H Jones, T W Robbin. Differential effects of mesocortical, mesolimbic, and mesostriatal dopamine depletion on spontaneous, conditioned, and drug-induced locomotor activity. Pharmacology, biochemistry, and behavior. vol 43. issue 3. 1992-12-30. PMID:1448483. |
groups of rats with 6-hydroxydopamine (6-ohda) lesions of either the medial prefrontal cortex (pfc), nucleus accumbens (nac), or caudate putamen (cpu) were given daily tests for locomotor activity in photocell cages while food deprived. |
1992-12-30 |
2023-08-11 |
human |
| G H Jones, T D Hernandez, D A Kendall, C A Marsden, T W Robbin. Dopaminergic and serotonergic function following isolation rearing in rats: study of behavioural responses and postmortem and in vivo neurochemistry. Pharmacology, biochemistry, and behavior. vol 43. issue 1. 1992-11-02. PMID:1384071. |
in experiment 2, isolates had higher postmortem dopamine (da) concentrations and an altered asymmetry in da function in the medial prefrontal cortex (pfc) but not in the nucleus accumbens (nac) or caudate putamen (cpu). |
1992-11-02 |
2023-08-11 |
rat |
| T Inoue, T Koyama, I Yamashit. [From a standpoint of psychiatry: effects of conditioned fear stress on monoaminergic systems in the rat brain]. Rinsho byori. The Japanese journal of clinical pathology. vol 40. issue 3. 1992-10-06. PMID:1355572. |
efs for 30 min increased dopac and hva levels in all seven brain regions and increased 5-hiaa levels in the medial prefrontal cortex(mpfc), nucleus accumbens and amygdala. |
1992-10-06 |
2023-08-11 |
rat |
| C K Meshul, A Janowsky, D E Casey, R K Stallbaumer, B Taylo. Effect of haloperidol and clozapine on the density of "perforated" synapses in caudate, nucleus accumbens, and medial prefrontal cortex. Psychopharmacology. vol 106. issue 1. 1992-03-18. PMID:1531388. |
administration of haloperidol for 2 weeks significantly increased the percentage of perforated synapses in the caudate, but not in the nucleus accumbens or layer vi of medial prefrontal cortex (mpcx). |
1992-03-18 |
2023-08-11 |
Not clear |
| C A Leslie, M W Robertson, A J Cutler, J P Bennet. Postnatal development of D1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: a quantitative autoradiographic analysis. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1836980. |
postnatal development of d1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: a quantitative autoradiographic analysis. |
1992-02-12 |
2023-08-11 |
rat |
| C A Leslie, M W Robertson, A J Cutler, J P Bennet. Postnatal development of D1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: a quantitative autoradiographic analysis. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1836980. |
the postnatal development of dopamine (da) d1 receptors in the medial prefrontal cortex (mpfc), striatum (str) and nucleus accumbens (nac) of control and perinatally 6-hydroxydopamine (6-ohda) lesioned rats was examined using quantitative autoradiography of 3h-sch 23390 binding. |
1992-02-12 |
2023-08-11 |
rat |
| N E Goeder. Cocaine differentially affects benzodiazepine receptors in discrete regions of the rat brain: persistence and potential mechanisms mediating these effects. The Journal of pharmacology and experimental therapeutics. vol 259. issue 2. 1991-12-24. PMID:1658304. |
bzd receptor binding was increased significantly in the caudate nucleus and decreased in the substantia nigra for up to 2 days after the final injection, whereas binding was decreased in the nucleus accumbens and medial prefrontal cortex and increased in the ventral tegmental area after daily injections of cocaine for 15 days. |
1991-12-24 |
2023-08-11 |
rat |
| J N Carlson, L W Fitzgerald, R W Keller, S D Glic. Side and region dependent changes in dopamine activation with various durations of restraint stress. Brain research. vol 550. issue 2. 1991-10-07. PMID:1884238. |
exposure to various mild stressors has been shown to result in the activation of dopamine containing neuronal systems projecting to the medial prefrontal cortex (pfc), to a lesser extent the nucleus accumbens septi/olfactory tubercle (nas) and, in a few studies, the striatum. |
1991-10-07 |
2023-08-11 |
Not clear |
| D W Clow, R P Hamme. Cocaine abstinence following chronic treatment alters cerebral metabolism in dopaminergic reward regions. Bromocriptine enhances recovery. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 4. issue 1. 1991-04-22. PMID:2003868. |
cocaine abstinence following chronic treatment significantly reduced lcgu in several regions including mesocorticolimbic structures such as ventral tegmental area, medial prefrontal cortex, and nucleus accumbens (nac). |
1991-04-22 |
2023-08-11 |
rat |
| G E Jaskiw, F K Karoum, D R Weinberge. Persistent elevations in dopamine and its metabolites in the nucleus accumbens after mild subchronic stress in rats with ibotenic acid lesions of the medial prefrontal cortex. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:2073594. |
persistent elevations in dopamine and its metabolites in the nucleus accumbens after mild subchronic stress in rats with ibotenic acid lesions of the medial prefrontal cortex. |
1991-04-18 |
2023-08-11 |
rat |
| E Museo, R A Wis. Microinjections of a nicotinic agonist into dopamine terminal fields: effects on locomotion. Pharmacology, biochemistry, and behavior. vol 37. issue 1. 1991-02-01. PMID:2263652. |
the present study determined the effects on locomotion of direct microinjections of the nicotinic agonist cytisine into four da terminal fields were nicotinic receptors have been localized: nucleus accumbens (nas, n = 20), caudate putamen (cpu, n = 9), olfactory tubercle (ot, n = 8), and medial prefrontal cortex (mpc, n = 12). |
1991-02-01 |
2023-08-11 |
rat |
| J T Qiao, P M Dougherty, R C Wiggins, N Dafn. Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats. Neuropharmacology. vol 29. issue 4. 1990-06-27. PMID:2342637. |
effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats. |
1990-06-27 |
2023-08-11 |
rat |
| J T Qiao, P M Dougherty, R C Wiggins, N Dafn. Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats. Neuropharmacology. vol 29. issue 4. 1990-06-27. PMID:2342637. |
the spontaneous extracellular electrical activity of 102 neurons, within the caudate nucleus (cn), medial prefrontal cortex (mpc), nucleus accumbens (nac) and a control site, the lateral thalamic nucleus (lt), was studied. |
1990-06-27 |
2023-08-11 |
rat |
| W J McBride, J M Murphy, L Lumeng, T K L. Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats. Alcohol (Fayetteville, N.Y.). vol 7. issue 3. 1990-06-05. PMID:2184832. |
neurochemical data indicate that high alcohol-seeking behavior (when compared with data from rats with low alcohol-seeking characteristics) is associated with: a) lower (10-20%; p less than 0.05) contents of 5-ht in certain limbic regions (e.g., nucleus accumbens, frontal cortex, hypothalamus and hippocampus); b) a lower (10-15%; p less than 0.05) content of da in the nucleus accumbens; c) higher (20-35%; p less than 0.05) densities of 5-ht1a binding sites in some limbic regions (e.g., medial nucleus accumbens, medial prefrontal cortex and ventral hippocampus); and d) a greater (20-50%) density of gaba axon terminals in the nucleus accumbens. |
1990-06-05 |
2023-08-11 |
rat |
| B Moghaddam, B S Bunne. Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: an in vivo microdialysis study. Journal of neurochemistry. vol 54. issue 5. 1990-05-18. PMID:1969939. |
the effect of haloperidol was also attenuated in the medial prefrontal cortex; 0.1 mg/kg did not increase the outflow of dopamine and the effect of 0.5 mg/kg haloperidol was of shorter duration in the prefrontal cortex than that observed in striatum and nucleus accumbens. |
1990-05-18 |
2023-08-11 |
rat |
| S D Glick, J N Carlso. Regional changes in brain dopamine and serotonin metabolism induced by conditioned circling in rats: effects of water deprivation, learning and individual differences in asymmetry. Brain research. vol 504. issue 2. 1990-02-06. PMID:2598025. |
after achieving criterion performance (100 full turns per hour) for at least 10 consecutive sessions, rats were sacrificed 20 min after starting a session and levels of dopamine, dopac (3,4-dihydroxyphenylacetic acid), serotonin, and 5-hiaa (5-hydroxyindoleacetic acid) were assayed in nigrostriatal (corpus striatum), mesolimbic (nucleus accumbens) and mesocortical (medial prefrontal cortex) brain regions. |
1990-02-06 |
2023-08-11 |
rat |
| P W Kalivas, P Duffy, J Barro. Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes. The Journal of pharmacology and experimental therapeutics. vol 251. issue 1. 1989-11-07. PMID:2552079. |
whereas glutamate was found to increase the postmortem concentration of dopamine metabolites in the medial prefrontal cortex, nucleus accumbens and a10 region, nmda selectively increased dopamine metabolism in the prefrontal cortex, and kainate produced increases in the nucleus accumbens and a10 region. |
1989-11-07 |
2023-08-11 |
rat |
| B Moghaddam, B S Bunne. Differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: comparison to amphetamine. Synapse (New York, N.Y.). vol 4. issue 2. 1989-10-19. PMID:2781466. |
differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: comparison to amphetamine. |
1989-10-19 |
2023-08-11 |
rat |
| B Moghaddam, B S Bunne. Differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: comparison to amphetamine. Synapse (New York, N.Y.). vol 4. issue 2. 1989-10-19. PMID:2781466. |
the technique of in vivo microdialysis was used to measure the extracellular levels of dopamine in the nucleus accumbens septi and medial prefrontal cortex of chloral-hydrate-anaesthetized rats following systemic administration of cocaine and amphetamine. |
1989-10-19 |
2023-08-11 |
rat |