| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lia Forti, Elona Ndoj, Jessica Mingardi, Emanuele Secchi, Tiziana Bonifacino, Emanuele Schiavon, Giulia Carini, Luca La Via, Isabella Russo, Marco Milanese, Massimo Gennarelli, Giambattista Bonanno, Maurizio Popoli, Alessandro Barbon, Laura Musazz. Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240064. |
here, we asked if acute fs may also induce any changes in glutamatergic synaptic plasticity in the pfc 24 h after stress exposure and whether ketamine administration 6 h after stress may have any effect. |
2023-05-27 |
2023-08-14 |
rat |
| Lia Forti, Elona Ndoj, Jessica Mingardi, Emanuele Secchi, Tiziana Bonifacino, Emanuele Schiavon, Giulia Carini, Luca La Via, Isabella Russo, Marco Milanese, Massimo Gennarelli, Giambattista Bonanno, Maurizio Popoli, Alessandro Barbon, Laura Musazz. Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240064. |
although more studies are needed to understand the effects of acute stress and ketamine on pfc glutamatergic plasticity, this first report suggests a restoring effect of acute ketamine, supporting the potential benefit of ketamine in limiting the impact of acute traumatic stress. |
2023-05-27 |
2023-08-14 |
rat |
| Daniela Lescano Uliana, Cassiano Ricardo Alves Faria Diniz, Leandro Antero da Silva, Anna Bárbara Borges-Assis, Sabrina Francesca Lisboa, Leonardo Barbosa Moraes Resste. Contextual fear expression engages a complex set of interactions between ventromedial prefrontal cortex cholinergic, glutamatergic, nitrergic and cannabinergic signaling. Neuropharmacology. 2023-04-06. PMID:37024011. |
contextual fear expression engages a complex set of interactions between ventromedial prefrontal cortex cholinergic, glutamatergic, nitrergic and cannabinergic signaling. |
2023-04-06 |
2023-08-14 |
rat |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
glutamatergic projections from the prefrontal cortex to some brain regions are present in the reward circuit. |
2023-04-05 |
2023-08-14 |
Not clear |
| Yiting Hu, Fang Dong, Ting Xue, Mi Zhou, Ruoyan Huang, Feng Sui, Qiang Guo, Wenbao Hou, Wenlong Cai, Kai Yuan, Hongde Wang, Dahua Y. Glutamate levels in the ventromedial prefrontal cortex and resting-state functional connectivity within reward circuits in alcohol-dependent patients. Addiction biology. vol 28. issue 4. 2023-04-05. PMID:37016753. |
the ventromedial prefrontal cortex (vmpfc) is believed to play a critical role in addiction disorders, and glutamatergic projections from the prefrontal cortex to several regions of the brain are present in reward circuits. |
2023-04-05 |
2023-08-14 |
Not clear |
| Sam Ej Paton, Caroline Menar. Glutamate shall not pass: a mechanistic role for astrocytic O-GlcNAc transferase in stress and depression. The Journal of clinical investigation. vol 133. issue 7. 2023-04-03. PMID:37009895. |
major depressive disorder, characterized by aberrant glutamatergic signaling in the prefrontal cortex (pfc), is a leading cause of disability worldwide. |
2023-04-03 |
2023-08-14 |
mouse |
| Roxana E Mesías, Yosif Zaki, Christopher A Guevara, Lauren G Friedman, Ayan Hussein, Karen Therrien, Alexandra R Magee, Nikolaos Tzavaras, Pamela Del Valle, Mark G Baxter, George W Huntley, Deanna L Benso. Development of prefrontal corticostriatal connectivity in mice. bioRxiv : the preprint server for biology. 2023-03-30. PMID:36993639. |
as corticostriatal synapse density increased over late postnatal ages, the strength of evoked pfc input onto dorsomedial striatal projection neurons also increased, but spontaneous glutamatergic synaptic activity was stable. |
2023-03-30 |
2023-08-14 |
mouse |
| Kate Merritt, Robert A McCutcheon, André Aleman, Sarah Ashley, Katherine Beck, Wolfgang Block, Oswald J N Bloemen, Faith Borgan, Christiana Boules, Juan R Bustillo, Aristides A Capizzano, Jennifer M Coughlin, Anthony David, Camilo de la Fuente-Sandoval, Arsime Demjaha, Kara Dempster, Kim Q Do, Fei Du, Peter Falkai, Beata Galińska-Skok, Jürgen Gallinat, Charles Gasparovic, Cedric E Ginestet, Naoki Goto, Ariel Graff-Guerrero, Beng-Choon Ho, Oliver Howes, Sameer Jauhar, Peter Jeon, Tadafumi Kato, Charles A Kaufmann, Lawrence S Kegeles, Matcheri S Keshavan, Sang-Young Kim, Bridget King, Hiroshi Kunugi, J Lauriello, Pablo León-Ortiz, Edith Liemburg, Meghan E Mcilwain, Gemma Modinos, Elias Mouchlianitis, Jun Nakamura, Igor Nenadic, Dost Öngür, Miho Ota, Lena Palaniyappan, Christos Pantelis, Tulsi Patel, Eric Plitman, Sotirios Posporelis, Scot E Purdon, Jürgen R Reichenbach, Perry F Renshaw, Francisco Reyes-Madrigal, Bruce R Russell, Akira Sawa, Martin Schaefer, Dikoma C Shungu, Stefan Smesny, Jeffrey A Stanley, James Stone, Agata Szulc, Reggie Taylor, Katharine N Thakkar, Jean Théberge, Philip G Tibbo, Thérèse van Amelsvoort, Jerzy Walecki, Peter C Williamson, Stephen J Wood, Lijing Xin, Hidenori Yamasue, Philip McGuire, Alice Egerto. Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis. Molecular psychiatry. 2023-02-22. PMID:36806762. |
compared with controls, patients demonstrated greater variability in glutamatergic metabolites in the medial frontal cortex (mfc, glutamate: cvr = 0.15, p < 0.001; glutamine: cvr = 0.15, p = 0.003; glx: cvr = 0.11, p = 0.002), dorsolateral prefrontal cortex (glutamine: cvr = 0.14, p = 0.05; glx: cvr = 0.25, p < 0.001) and thalamus (glutamate: cvr = 0.16, p = 0.008; glx: cvr = 0.19, p = 0.008). |
2023-02-22 |
2023-08-14 |
Not clear |
| Yiwen Hou, Guichang Zou, Xianglian Wang, Hui Guo, Xiao Ma, Xingyu Cheng, Zhiyong Xie, Xin Zuo, Jing Xia, Huanhuan Mao, Man Yuan, Qi Chen, Peng Cao, Yupeng Yang, Li Zhang, Wei Xion. Coordinated activity of a central pathway drives associative opioid analgesic tolerance. Science advances. vol 9. issue 6. 2023-02-08. PMID:36753548. |
the association of morphine-induced analgesia with an environmental condition drives glutamatergic signaling from ventral hippocampus (vhpc) to dorsomedial prefrontal cortex (dmpfc) cholecystokininergic (cckergic) neurons. |
2023-02-08 |
2023-08-14 |
Not clear |
| Hao Jiang, Rongrong Li, Fan Zhang, Feini Zhou, Jiangnan Lin, Ning Kong, Haitao Chen, Lingnan Guo, Chenxiao Ye, Fuhao Li, Maosheng X. Electroacupuncture Alleviates 46-Trinitrobenzene Sulfonic Acid-Induced Visceral Pain via the Glutamatergic Pathway in the Prefrontal Cortex. Oxidative medicine and cellular longevity. vol 2023. 2023-01-30. PMID:36713031. |
electroacupuncture alleviates 46-trinitrobenzene sulfonic acid-induced visceral pain via the glutamatergic pathway in the prefrontal cortex. |
2023-01-30 |
2023-08-14 |
Not clear |
| Nina Treder, Albert Martínez-Pinteño, Natalia Rodríguez, Néstor Arbelo, Santiago Madero, Marta Gómez, Clemente García-Rizo, Sergi Mas, Patricia Gassó, Eduard Parellada, Constanza Moré. The Effect of Clozapine and Novel Glutamate Modulator JNJ-46356479 on Nitrosative Stress in a Postnatal Murine Ketamine Model of Schizophrenia. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674542. |
regarding glutamatergic models of sz, the administration of nmdar antagonists has been found to increase nos levels in the prefrontal cortex (pfc) and ventral hippocampus (hpc). |
2023-01-21 |
2023-08-14 |
Not clear |
| Sarah Beggiato, Alessandro Ieraci, Mariachiara Zuccarini, Patrizia Di Iorio, Robert Schwarcz, Luca Ferrar. Alterations in rat prefrontal cortex kynurenic acid levels are involved in the enduring cognitive dysfunctions induced by tetrahydrocannabinol exposure during the adolescence. Frontiers in psychiatry. vol 13. 2022-12-09. PMID:36483135. |
early exposure to delta 9-tetrahydrocannabinol (thc; i.e., the main psychotropic component of cannabis) causes enduring cognitive deficits, which critically involve impaired glutamatergic function in the prefrontal cortex (pfc). |
2022-12-09 |
2023-08-14 |
rat |
| Chelsea Hook, Adam C Puch. Bulbar projecting subcortical GABAergic neurons send collateral branches extensively and selectively to primary olfactory cortical regions. The Journal of comparative neurology. 2022-12-03. PMID:36463397. |
multiple glutamatergic regions project to the olfactory bulb, including the anterior olfactory nucleus (aon), prefrontal cortex (pfc), piriform cortex (pc), entorhinal cortex (ec), and tenia tecta (tt). |
2022-12-03 |
2023-08-14 |
Not clear |
| Alice Taddeucci, Guendalina Olivero, Alessandra Roggeri, Claudio Milanese, Francesco Paolo Di Giorgio, Massimo Grilli, Mario Marchi, Beatrice Garrone, Anna Pittalug. Presynaptic 5-HT Cells. vol 11. issue 19. 2022-10-14. PMID:36230998. |
presynaptic 5-ht the glutamatergic nerve endings of a rat prefrontal cortex (pfc) possess presynaptic 5-ht |
2022-10-14 |
2023-08-14 |
rat |
| Zhifeng Zhou, Pamela Metten, Qiaoping Yuan, Hui Sun, Colin A Hodgkinson, Pei-Hong Shen, Cheryl Marietta, John C Crabbe, David Goldma. Genetic and genomic signatures in ethanol withdrawal seizure-prone and seizure-resistant mice implicate genes involved in epilepsy and neuronal excitability. Molecular psychiatry. 2022-10-05. PMID:36198764. |
perturbations of expression of genes involved in synaptic transmission, including gabaergic and glutamatergic genes, were prominent in prefrontal cortex transcriptome. |
2022-10-05 |
2023-08-14 |
mouse |
| Abhishek Mishra, Rubal Singla, Rohit Kumar, AmitRaj Sharma, Rupa Joshi, Phulen Sarma, Gurjeet Kaur, Manisha Prajapat, Alka Bhatia, Bikash Medh. Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains. ACS chemical neuroscience. 2022-09-27. PMID:36166499. |
granulocyte colony-stimulating factor improved core symptoms of autism spectrum disorder via modulating glutamatergic receptors in the prefrontal cortex and hippocampus of rat brains. |
2022-09-27 |
2023-08-14 |
rat |
| Jelena Martinovic, Marina Zaric Kontic, Milorad Dragic, Ana Todorovic, Ivana Gusevac Stojanovic, Natasa Mitrovic, Ivana Grkovic, Dunja Drakuli. Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex. Behavioural brain research. 2022-08-28. PMID:36030906. |
memory assessment was followed by histological examination of the pfc and hip (nissl staining and iba-1 immunostaining), while in crude synaptosomal fractions the state of oxidative stress and the expression of proteins involved in glutamatergic signaling was determined. |
2022-08-28 |
2023-08-14 |
rat |
| Megan Conrow-Graham, Jamal B Williams, Jennifer Martin, Ping Zhong, Qing Cao, Benjamin Rein, Zhen Ya. A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders. Brain : a journal of neurology. 2022-07-01. PMID:35775424. |
concomitantly, adnp or pogz deficiency led to the significant increase of pro-phagocytic microglial activation in prefrontal cortex, as well as the significant decrease of glutamatergic transmission and postsynaptic protein expression. |
2022-07-01 |
2023-08-14 |
mouse |
| Winston H Cuddleston, Junhao Li, Xuanjia Fan, Alexey Kozenkov, Matthew Lalli, Shahrukh Khalique, Stella Dracheva, Eran A Mukamel, Michael S Bree. Cellular and genetic drivers of RNA editing variation in the human brain. Nature communications. vol 13. issue 1. 2022-05-31. PMID:35637184. |
we quantify base-specific rna editing across three major cell populations from the human prefrontal cortex: glutamatergic neurons, medial ganglionic eminence-derived gabaergic neurons, and oligodendrocytes. |
2022-05-31 |
2023-08-13 |
human |
| Kshitij S Jadhav, Aurélien P Bernheim, Léa Aeschlimann, Guylène Kirschmann, Isabelle Decosterd, Alexander F Hoffman, Carl R Lupica, Benjamin Boutre. Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in adolescent rats. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 21. 2022-05-18. PMID:35584117. |
unexpectedly, we identified a lower excitability of layer 5 pyramidal neurons in the anterior insular cortex (aic) of adolescent rats and smaller synaptic glutamatergic inputs to these cells but no difference in layer 5 prefrontal cortex pyramidal neurons. |
2022-05-18 |
2023-08-13 |
rat |