| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucia Caffino, Francesca Mottarlini, Boyd Van Reijmersdal, Francesca Telese, Michel M M Verheij, Fabio Fumagalli, Judith R Homber. The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. Addiction biology. vol 26. issue 2. 2021-03-26. PMID:32187792. |
the role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. |
2021-03-26 |
2023-08-13 |
Not clear |
| Placido Illiano, Damiana Leo, Raul R Gainetdinov, Marta Pard. Early Adolescence Prefrontal Cortex Alterations in Female Rats Lacking Dopamine Transporter. Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33562738. |
in brief, we observed a concurrent hyperactive phenotype, accompanied by pfc alterations in glutamatergic neurotransmission, signs of neurodegeneration and glial activation in dat-ablated rats. |
2021-03-16 |
2023-08-13 |
human |
| G Siano, M Varisco, A Scarlatti, M C Caiazza, K Dunville, F Cremisi, M Costa, L Pancrazi, C Di Primio, A Cattane. Gene Expression of Disease-related Genes in Alzheimer's Disease is Impaired by Tau Aggregation. Journal of molecular biology. vol 432. issue 24. 2021-03-04. PMID:33058882. |
together, this evidence links the altered glutamatergic function in the pfc during ad progression to the newly discovered function of nuclear tau. |
2021-03-04 |
2023-08-13 |
Not clear |
| Patricia Rivera, Rubén Tovar, María Teresa Ramírez-López, Juan Antonio Navarro, Antonio Vargas, Juan Suárez, Fernando Rodríguez de Fonsec. Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model. Nutrients. vol 12. issue 6. 2021-03-01. PMID:32575416. |
sex-specific anxiety and prefrontal cortex glutamatergic dysregulation are long-term consequences of pre-and postnatal exposure to hypercaloric diet in a rat model. |
2021-03-01 |
2023-08-13 |
rat |
| Patricia Rivera, Rubén Tovar, María Teresa Ramírez-López, Juan Antonio Navarro, Antonio Vargas, Juan Suárez, Fernando Rodríguez de Fonsec. Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model. Nutrients. vol 12. issue 6. 2021-03-01. PMID:32575416. |
to this end, we examined both anxiety responses and the mrna/protein expression of glutamatergic, gabaergic and endocannabinoid signaling pathways in the prefrontal cortex of adult offspring. |
2021-03-01 |
2023-08-13 |
rat |
| Xiuping Sun, Yu Zhang, Xianglei Li, Xinmin Liu, Chuan Qi. Early-Life Neglect Alters Emotional and Cognitive Behavior in a Sex-Dependent Manner and Reduces Glutamatergic Neuronal Excitability in the Prefrontal Cortex. Frontiers in psychiatry. vol 11. 2021-02-13. PMID:33574771. |
early-life neglect alters emotional and cognitive behavior in a sex-dependent manner and reduces glutamatergic neuronal excitability in the prefrontal cortex. |
2021-02-13 |
2023-08-13 |
mouse |
| Xiuping Sun, Yu Zhang, Xianglei Li, Xinmin Liu, Chuan Qi. Early-Life Neglect Alters Emotional and Cognitive Behavior in a Sex-Dependent Manner and Reduces Glutamatergic Neuronal Excitability in the Prefrontal Cortex. Frontiers in psychiatry. vol 11. 2021-02-13. PMID:33574771. |
no studies to date have examined the impact of early-life stress on glutamatergic neuronal excitability in the pfc. |
2021-02-13 |
2023-08-13 |
mouse |
| Xiuping Sun, Yu Zhang, Xianglei Li, Xinmin Liu, Chuan Qi. Early-Life Neglect Alters Emotional and Cognitive Behavior in a Sex-Dependent Manner and Reduces Glutamatergic Neuronal Excitability in the Prefrontal Cortex. Frontiers in psychiatry. vol 11. 2021-02-13. PMID:33574771. |
this study aimed to develop a reliable child neglect rat model and observe glutamatergic neuronal excitability in the pfc. |
2021-02-13 |
2023-08-13 |
mouse |
| Mei-Yu Chen, Yang Chen, Hui Liu, An-Feng Xiang, Xue-Qi Wang, Xue-Yong Shen, Sheng Li. [Effect of electroacupuncture on morphine-conditioned place preference and activation of glutamatergic neurons in the ventromedial prefrontal cortex in rats]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 1. 2021-02-10. PMID:33559419. |
[effect of electroacupuncture on morphine-conditioned place preference and activation of glutamatergic neurons in the ventromedial prefrontal cortex in rats]. |
2021-02-10 |
2023-08-13 |
rat |
| Mei-Yu Chen, Yang Chen, Hui Liu, An-Feng Xiang, Xue-Qi Wang, Xue-Yong Shen, Sheng Li. [Effect of electroacupuncture on morphine-conditioned place preference and activation of glutamatergic neurons in the ventromedial prefrontal cortex in rats]. Zhen ci yan jiu = Acupuncture research. vol 46. issue 1. 2021-02-10. PMID:33559419. |
to observe the effect of electroacupuncture (ea) at "zusanli"(st36) and "sanyinjiao"(sp6) on conditioned place preference (cpp) and activation of glutamatergic neurons in the ventromedial prefrontal cortex (vmpfc) of morphine-addiction rats, so as to explore its mechanisms underlying detoxification. |
2021-02-10 |
2023-08-13 |
rat |
| Xiao-Yang Zhang, Shi-Yu Peng, Li-Ping Shen, Qian-Xing Zhuang, Bin Li, Shu-Tao Xie, Qian-Xiao Li, Ming-Run Shi, Tian-Yu Ma, Qipeng Zhang, Jian-Jun Wang, Jing-Ning Zh. Targeting presynaptic H3 heteroreceptor in nucleus accumbens to improve anxiety and obsessive-compulsive-like behaviors. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 50. 2021-02-01. PMID:33257584. |
here we report an amelioration of both anxiety and ocd via the histamine presynaptic h3 heteroreceptor on glutamatergic afferent terminals from the prelimbic prefrontal cortex (prl) to the nucleus accumbens (nac) core, a vital node in the limbic loop. |
2021-02-01 |
2023-08-13 |
Not clear |
| N N Dygalo, D A Lanshakov, N P Komysheva, U S Drozd, E V Shaburova, E V Sukhareva, G T Shishkin. Chemogenetic Activation of Glutamatergic Neurons in the Juvenile Rat Cortex Reduces Anxiety. Doklady. Biochemistry and biophysics. vol 490. issue 1. 2021-01-26. PMID:32342305. |
abstract-chemogenetic activation of glutamatergic neurons of the prefrontal cortex reduces the manifestations of psychoemotional anxiety during the juvenile period of ontogenesis. |
2021-01-26 |
2023-08-13 |
rat |
| Samuel Rupprechter, Liana Romaniuk, Peggy Series, Yoriko Hirose, Emma Hawkins, Anca-Larisa Sandu, Gordon D Waiter, Christopher J McNeil, Xueyi Shen, Mathew A Harris, Archie Campbell, David Porteous, Jennifer A Macfarlane, Stephen M Lawrie, Alison D Murray, Mauricio R Delgado, Andrew M McIntosh, Heather C Whalley, J Douglas Steel. Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression. Brain : a journal of neurology. vol 143. issue 6. 2021-01-19. PMID:32385498. |
reduced effect of glutamatergic projections from the prefrontal cortex to the nucleus accumbens has been argued to underlie motivational disorders such as depression, and many prominent theories of major depressive disorder propose a role for abnormal cortico-limbic connectivity. |
2021-01-19 |
2023-08-13 |
human |
| Anupa A Vijayakumari, Ramshekhar N Menon, Bejoy Thomas, Thumboli Muyyayil Arun, Mohanan Nandini, Chandrasekharan Kesavada. Glutamatergic response to a low load working memory paradigm in the left dorsolateral prefrontal cortex in patients with mild cognitive impairment: a functional magnetic resonance spectroscopy study. Brain imaging and behavior. vol 14. issue 2. 2021-01-04. PMID:31102169. |
glutamatergic response to a low load working memory paradigm in the left dorsolateral prefrontal cortex in patients with mild cognitive impairment: a functional magnetic resonance spectroscopy study. |
2021-01-04 |
2023-08-13 |
Not clear |
| Stefania Schiavone, Maria Grazia Morgese, Maria Bove, Anna Laura Colia, Angela Bruna Maffione, Paolo Tucci, Luigia Trabace, Vincenzo Cuom. Ketamine administration induces early and persistent neurochemical imbalance and altered NADPH oxidase in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31446158. |
to this purpose, we evaluated glutamatergic, glutamine and gabaergic tissue levels, as well as pv amount in the pfc, both two hours after the last ketamine injection (pnd 11) and at 10 weeks of age. |
2021-01-04 |
2023-08-13 |
mouse |
| Virginia M Pickel, Faye Bourie, June Chan, Ken Mackie, Diane A Lane, Gang Wan. Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 2. 2020-12-28. PMID:31323660. |
cannabinoid-1 receptors (cb1rs) largely mediate the central neural effects of ∆9-thc and endocannabinoids that regulate nmda receptor-dependent synaptic plasticity of glutamatergic synapses in the prelimbic prefrontal cortex (pl-pfc). |
2020-12-28 |
2023-08-13 |
mouse |
| Zijun Zhao, Wen Zhang, Yuan Zhang, Yun Zhao, Chunxiang Zheng, Huiling Tian, Jianfeng Lei, Yan Liu, Ruizhen Zhao, Qisheng Tan. Multimodal Magnetic Resonance Imaging and Therapeutic Intervention With Yi-nao-jie-yu Decoction in a Rat Model of Post-stroke Depression. Frontiers in psychiatry. vol 11. 2020-12-18. PMID:33329096. |
furthermore, we found that psd rats had lower perfusion levels in the prefrontal cortex (pfc) and hippocampus (hp), microstructural damage, and abnormal changes in the concentrations of brain metabolites; ynjyd exerted therapeutic effects on psd rats by improving microcirculation in the pfc and hp, regulating glutamatergic systems and membrane phospholipid metabolism, and repairing microstructural damage. |
2020-12-18 |
2023-08-13 |
rat |
| Mads E Hauberg, Jordi Creus-Muncunill, Jaroslav Bendl, Alexey Kozlenkov, Biao Zeng, Chuhyon Corwin, Sarah Chowdhury, Harald Kranz, Yasmin L Hurd, Michael Wegner, Anders D Børglum, Stella Dracheva, Michelle E Ehrlich, John F Fullard, Panos Rousso. Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons. Nature communications. vol 11. issue 1. 2020-12-04. PMID:33149216. |
here we use atac-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic neurons, gabaergic neurons, oligodendrocytes, and microglia/astrocytes) from three different brain regions (anterior cingulate cortex, dorsolateral prefrontal cortex, and primary visual cortex) in human postmortem brain samples. |
2020-12-04 |
2023-08-13 |
mouse |
| Meng Li, Marie Woelfer, Lejla Colic, Adam Safron, Catie Chang, Hans-Jochen Heinze, Oliver Speck, Helen S Mayberg, Bharat B Biswal, Giacomo Salvadore, Anna Fejtova, Martin Walte. Default mode network connectivity change corresponds to ketamine's delayed glutamatergic effects. European archives of psychiatry and clinical neuroscience. vol 270. issue 2. 2020-11-06. PMID:30353262. |
fc decrease between pcc and dorsomedial prefrontal cortex (dmpfc) was found at 24 h post-infusion (but not 1 h) and this fc decrease correlated with glutamatergic changes at 24 h in pgacc. |
2020-11-06 |
2023-08-13 |
human |
| Mengxin Shen, Dan Lv, Shuting Li, Yanhua Zhang, Zhen Wang, Chiyu Zhao, Xuejie Chen, Chuang Wan. Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 10. 2020-10-13. PMID:30566581. |
it has been reported that fast-acting antidepressants enhance glutamatergic neurotransmission in the prefrontal cortex (pfc) regions via alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar) activation. |
2020-10-13 |
2023-08-13 |
mouse |