| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
the role of microglia in the neurogenesis of zebrafish retina. |
2012-07-09 |
2023-08-12 |
zebrafish |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
in zebrafish, early macrophages migrate from the yolk sac to the brain and retina at 26-30 hour post fertilization (hpf) and transform into microglia at 55-60 hpf. |
2012-07-09 |
2023-08-12 |
zebrafish |
| Tao Huang, Jianlin Cui, Lei Li, Peter F Hitchcock, Yuhao L. The role of microglia in the neurogenesis of zebrafish retina. Biochemical and biophysical research communications. vol 421. issue 2. 2012-07-09. PMID:22497888. |
when embryos were allowed to survive beyond the time when morpholino-dependent translation inhibition is lost, microglia re-occupy the retina and neuronal differentiation partially recovers. |
2012-07-09 |
2023-08-12 |
zebrafish |
| D R Howlett, S T Bate, S Collier, A Lawman, T Chapman, T Ashmeade, I Marshall, P J B Anderson, K L Philpott, J C Richardson, C J Hill. Characterisation of amyloid-induced inflammatory responses in the rat retina. Experimental brain research. vol 214. issue 2. 2012-06-26. PMID:21850448. |
histology and mrna endpoints in the retina demonstrate aβ1-42-, but not aβ42-1-, induced inflammatory responses characterised by increases in markers for microglia and astrocytes (ionised calcium-binding adaptor molecule 1 (iba-1), gfap and nestin) and increases in mrna for inflammatory cytokines and chemokines such as il1-β, mip1α and tnfα. |
2012-06-26 |
2023-08-12 |
rat |
| Richard Fairless, Sarah K Williams, Dorit B Hoffmann, Aleksandar Stojic, Sonja Hochmeister, Frank Schmitz, Maria K Storch, Ricarda Die. Preclinical retinal neurodegeneration in a model of multiple sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 16. 2012-06-12. PMID:22514320. |
in addition, we observed an early activation of resident microglia in the retina. |
2012-06-12 |
2023-08-12 |
rat |
| Neal D Heuss, Ute Lehmann, Christopher C Norbury, Scott W McPherson, Dale S Gregerso. Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina. Journal of immunology (Baltimore, Md. : 1950). vol 188. issue 3. 2012-06-11. PMID:22219322. |
we recently reported that dendritic cells (dc) distinct from microglia were present in quiescent retina and rapidly responded to injured neurons. |
2012-06-11 |
2023-08-12 |
Not clear |
| Raymond Iezzi, Bharath R Guru, Inna V Glybina, Manoj K Mishra, Alexander Kennedy, Rangaramanujam M Kanna. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials. vol 33. issue 3. 2012-05-29. PMID:22048009. |
we show that, upon intravitreal administration, pamam dendrimers selectively localize within activated outer retinal microglia in two rat models of retinal degeneration, but not in the retina of healthy controls. |
2012-05-29 |
2023-08-12 |
rat |
| Wenxin Ma, Lian Zhao, Wai T Won. Microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. Advances in experimental medicine and biology. vol 723. 2012-04-13. PMID:22183313. |
microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration. |
2012-04-13 |
2023-08-12 |
Not clear |
| Jerome E Roger, Keerthi Ranganath, Lian Zhao, Radu I Cojocaru, Matthew Brooks, Norimoto Gotoh, Shobi Veleri, Avinash Hiriyanna, Rivka A Rachel, Maria Mercedes Campos, Robert N Fariss, Wai T Wong, Anand Swaroo. Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 2. 2012-03-06. PMID:22238088. |
here, we report that nrl(-/-) retina undergoes a rapid but transient period of degeneration in early adulthood, with cone apoptosis, retinal detachment, alterations in retinal vessel structure, and activation and translocation of retinal microglia. |
2012-03-06 |
2023-08-12 |
mouse |
| Jerome E Roger, Keerthi Ranganath, Lian Zhao, Radu I Cojocaru, Matthew Brooks, Norimoto Gotoh, Shobi Veleri, Avinash Hiriyanna, Rivka A Rachel, Maria Mercedes Campos, Robert N Fariss, Wai T Wong, Anand Swaroo. Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 2. 2012-03-06. PMID:22238088. |
at this stage, microglia translocate back to the inner retina and reacquire a quiescent morphology. |
2012-03-06 |
2023-08-12 |
mouse |
| Holly R Chinnery, Samuel McLenachan, Nicolette Binz, Yan Sun, John V Forrester, Mariapia A Degli-Esposti, Eric Pearlman, Paul G McMenami. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. The American journal of pathology. vol 180. issue 1. 2012-02-17. PMID:22085974. |
in vivo clinical examination at 24 hours revealed inflammatory infiltrates in the vitreous and retina, which were confirmed ex vivo to be neutrophils and macrophages, along with activated resident microglia. |
2012-02-17 |
2023-08-12 |
mouse |
| Holly R Chinnery, Samuel McLenachan, Nicolette Binz, Yan Sun, John V Forrester, Mariapia A Degli-Esposti, Eric Pearlman, Paul G McMenami. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. The American journal of pathology. vol 180. issue 1. 2012-02-17. PMID:22085974. |
fluorescein isothiocyanate-cpg-odn rapidly penetrated the cornea and ocular media to reach the retina, where it was present within cd68(+) retinal macrophages and microglia. |
2012-02-17 |
2023-08-12 |
mouse |
| Maria-Carmen Carrasco, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Ana M Santos, Ana Sierra, Rosa M Ferrer-Martín, José L Marín-Tev. Migration and ramification of microglia in quail embryo retina organotypic cultures. Developmental neurobiology. vol 71. issue 4. 2012-02-13. PMID:21394933. |
migration and ramification of microglia in quail embryo retina organotypic cultures. |
2012-02-13 |
2023-08-12 |
Not clear |
| Maria-Carmen Carrasco, Julio Navascués, Miguel A Cuadros, Ruth Calvente, David Martín-Oliva, Ana M Santos, Ana Sierra, Rosa M Ferrer-Martín, José L Marín-Tev. Migration and ramification of microglia in quail embryo retina organotypic cultures. Developmental neurobiology. vol 71. issue 4. 2012-02-13. PMID:21394933. |
during the first week in vitro, microglial cells migrated tangentially in the vitreal part of qerocs, and some began to migrate radially from 3 days in vitro (div) onward, ramifying in the inner and outer plexiform layers, thus mimicking microglia development in the retina in situ, although reaching a lower degree of ramification after 7 div. |
2012-02-13 |
2023-08-12 |
Not clear |
| Stefanie G Wohl, Christian W Schmeer, Thomas Friese, Otto W Witte, Stefan Isenman. In situ dividing and phagocytosing retinal microglia express nestin, vimentin, and NG2 in vivo. PloS one. vol 6. issue 8. 2012-02-02. PMID:21850226. |
thus, the present study evaluates expression of nestin and other neural markers in quiescent and proliferating microglia in naïve retina and following on transection in adult rats in vivo. |
2012-02-02 |
2023-08-12 |
rat |
| Viswanathan Sivakumar, Wallace S Foulds, Chi D Luu, Eng-Ang Ling, Charanjit Kau. Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. The Journal of pathology. vol 224. issue 2. 2011-07-25. PMID:21404274. |
retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. |
2011-07-25 |
2023-08-12 |
rat |
| Ortrud Uckermann, Susann Uhlmann, Antje Wurm, Andreas Reichenbach, Peter Wiedemann, Andreas Bringman. ADPbetaS evokes microglia activation in the rabbit retina in vivo. Purinergic signalling. vol 1. issue 4. 2011-07-14. PMID:18404523. |
adpbetas evokes microglia activation in the rabbit retina in vivo. |
2011-07-14 |
2023-08-12 |
rabbit |
| Alejandra Bosco, Michael R Steele, Monica L Vette. Early microglia activation in a mouse model of chronic glaucoma. The Journal of comparative neurology. vol 519. issue 4. 2011-04-18. PMID:21246546. |
exclusively in d2 mice, we detected early microglia clustering in the inner central retina and unmyelinated optic nerve regions, with microglia activation peaking by 3 months of age. |
2011-04-18 |
2023-08-12 |
mouse |
| Alejandra Bosco, Michael R Steele, Monica L Vette. Early microglia activation in a mouse model of chronic glaucoma. The Journal of comparative neurology. vol 519. issue 4. 2011-04-18. PMID:21246546. |
collectively, our findings suggest microglia activation is an early alteration in the retina and optic nerve in d2 glaucoma, potentially contributing to disease onset or progression. |
2011-04-18 |
2023-08-12 |
mouse |
| Ceren Ergorul, Arjun Ray, Wei Huang, Dan Yi Wang, Yixin Ben, Ippolita Cantuti-Castelvetri, Cynthia L Grosskreut. Hypoxia inducible factor-1α (HIF-1α) and some HIF-1 target genes are elevated in experimental glaucoma. Journal of molecular neuroscience : MN. vol 42. issue 2. 2011-04-04. PMID:20237864. |
we find that hif-1alpha protein was increased in the retina following elevation of intraocular pressure, specifically in müller glia and astrocytes but not in activated microglia. |
2011-04-04 |
2023-08-12 |
rat |