| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie J Ahn, Robert H Miller, Yusra Isla. Isolation of Pure Astrocytes and Microglia from the Adult Mouse Spinal Cord For In Vitro Assays and Transcriptomic Studies. Journal of visualized experiments : JoVE. issue 200. 2023-11-06. PMID:37930016. |
furthermore, focusing on spinal cord-specific isolation, excluding brain involvement, enables research into spinal cord pathologies, including experimental autoimmune encephalomyelitis, spinal cord injury, and amyotrophic lateral sclerosis. |
2023-11-06 |
2023-11-08 |
mouse |
| Anca Moțățăianu, Georgiana Șerban, Sebastian Andon. The Role of Short-Chain Fatty Acids in Microbiota-Gut-Brain Cross-Talk with a Focus on Amyotrophic Lateral Sclerosis: A Systematic Review. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37894774. |
amyotrophic lateral sclerosis is a devastating neurodegenerative disease characterized by the gradual loss of motor neurons in the brain and spinal cord, leading to progressive motor function decline. |
2023-10-30 |
2023-11-08 |
Not clear |
| Jun-Yang Liu, Yuan-Rong Lu, Jie Guo, Hua Li, Yuan Wang, Ying-Qian Zhao, Jie Li, Qiang Wan. Effect of electroacupuncture intervention on the spinal cord PPIA/NF-κB signaling pathway in mice with amyotrophic lateral sclerosis. Zhen ci yan jiu = Acupuncture research. vol 48. issue 10. 2023-10-25. PMID:37879951. |
effect of electroacupuncture intervention on the spinal cord ppia/nf-κb signaling pathway in mice with amyotrophic lateral sclerosis. |
2023-10-25 |
2023-11-08 |
mouse |
| Lijun Zhou, Wenzhi Chen, Shishi Jiang, Renshi X. In Vitro Models of Amyotrophic Lateral Sclerosis. Cellular and molecular neurobiology. 2023-10-23. PMID:37870685. |
amyotrophic lateral sclerosis (als) is one of the commonest neurodegenerative diseases of adult-onset, which is characterized by the progressive death of motor neurons in the cerebral cortex, brain stem and spinal cord. |
2023-10-23 |
2023-11-08 |
Not clear |
| Matthew W Holt, Eric C Robinson, Nathan A Shlobin, Jacob T Hanson, Ismail Bozkur. Intracortical brain-computer interfaces for improved motor function: a systematic review. Reviews in the neurosciences. 2023-10-17. PMID:37845811. |
the systems treated patients with various conditions: amyotrophic lateral sclerosis, stroke, spinocerebellar degeneration without cerebellar involvement, and spinal cord injury. |
2023-10-17 |
2023-11-08 |
human |
| Xinxin Wang, Yushu Hu, Renshi X. The pathogenic mechanism of TAR DNA-binding protein 43 (TDP-43) in amyotrophic lateral sclerosis. Neural regeneration research. vol 19. issue 4. 2023-10-16. PMID:37843214. |
the onset of amyotrophic lateral sclerosis is usually characterized by focal death of both upper and/or lower motor neurons occurring in the motor cortex, basal ganglia, brainstem, and spinal cord, and commonly involves the muscles of the upper and/or lower extremities, and the muscles of the bulbar and/or respiratory regions. |
2023-10-16 |
2023-11-08 |
Not clear |
| Soo Yeon Lee, Hye-Yeon Cho, Jung-Pyo Oh, Jiae Park, Sang-Hun Bae, Haesun Park, Eun Jung Kim, Ji-Hyun Le. Therapeutic Effects of Combination of Nebivolol and Donepezil: Targeting Multifactorial Mechanisms in ALS. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2023-10-02. PMID:37782409. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disorder characterized by progressive loss of motor neurons in the spinal cord. |
2023-10-02 |
2023-10-07 |
Not clear |
| Di Chen, Hongyun Huang, Hooshang Saberi, Hari Shanker Sharm. Positive and negative cell therapy in randomized control trials for central nervous system diseases. International review of neurobiology. vol 171. 2023-10-02. PMID:37783557. |
in this review, we summarized randomized clinical trials of cell therapies for central nervous diseases, such as stroke, spinal cord injury, cerebral palsy (cp), parkinson's disease (pd), multiple sclerosis (ms), brain trauma, amyotrophic lateral sclerosis (als), etc. |
2023-10-02 |
2023-10-07 |
Not clear |
| Wanglin Dong, Qianwen Peng, Zhuoxin Liu, Zhenxing Xie, Xiajun Guo, Yuanyuan Li, Chaoran Che. Estrogen plays an important role by influencing the NLRP3 inflammasome. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 167. 2023-09-22. PMID:37738797. |
estrogen can ameliorate some diseases (e. g, sepsis, mood disturbances, cerebral ischemia, some hepatopathy, parkinson's disease, amyotrophic lateral sclerosis, inflammatory bowel disease, spinal cord injury, multiple sclerosis, myocardial ischemia/reperfusion injury, osteoarthritis, and renal fibrosis) by inhibiting the nlrp3 inflammasome. |
2023-09-22 |
2023-10-07 |
Not clear |
| Serenella Anzilotti, Valeria Valente, Paola Brancaccio, Cristina Franco, Antonella Casamassa, Giovanna Lombardi, Alessandra Palazzi, Andrea Conte, Simona Paladino, Lorella Maria Teresa Canzoniero, Lucio Annunziato, Giovanna Maria Pierantoni, Giuseppe Pignatar. Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 167. 2023-09-20. PMID:37729728. |
amyotrophic lateral sclerosis (als) is a progressive and often fatal neurodegenerative disease characterized by the loss of motor neurons (mns) in spinal cord, motor cortex and brainstem. |
2023-09-20 |
2023-10-07 |
mouse |
| Jin Gao, Mingchen Jiang, Danilo Erricolo, Richard L Magin, Gerardo Morfini, Thomas Royston, Andrew C Larson, Weiguo L. Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue. NMR in biomedicine. 2023-09-18. PMID:37721118. |
identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: application of the continuous time random walk model to ultrahigh b-value diffusion-weighted mr images of spinal cord tissue. |
2023-09-18 |
2023-10-07 |
mouse |
| Matthew J Broadhead, Ani Ayvazian-Hancock, Katherine Doucet, Owen Kantelberg, Lesley Motherwell, Fei Zhu, Seth G N Grant, Mathew H Horrocks, Gareth B Mile. Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy. Frontiers in molecular neuroscience. vol 16. 2023-09-06. PMID:37671010. |
amyotrophic lateral sclerosis (als) is characterised by a loss of motor neurons in the brain and spinal cord that is preceded by early-stage changes in synapses that may be associated with tar-dna-binding protein 43 (tdp-43) pathology. |
2023-09-06 |
2023-10-07 |
mouse |
| Wan Zhou, Renshi X. Current insights in the molecular genetic pathogenesis of amyotrophic lateral sclerosis. Frontiers in neuroscience. vol 17. 2023-08-28. PMID:37638324. |
amyotrophic lateral sclerosis (als) is a progressive and fatal neurodegenerative disease that leads to the massive loss of motor neurons in cerebrum, brain stem and spinal cord. |
2023-08-28 |
2023-09-07 |
Not clear |
| Valentina La Cognata, Agata Grazia D'Amico, Grazia Maugeri, Giovanna Morello, Maria Guarnaccia, Benedetta Magrì, Eleonora Aronica, Daniel L Alkon, Velia D'Agata, Sebastiano Cavallar. The ε-Isozyme of Protein Kinase C (PKCε) Is Impaired in ALS Motor Cortex and Its Pulse Activation by Bryostatin-1 Produces Long Term Survival in Degenerating SOD1-G93A Motor Neuron-like Cells. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629005. |
amyotrophic lateral sclerosis (als) is a rapidly progressive and ultimately fatal neurodegenerative disease, characterized by a progressive depletion of upper and lower motor neurons (mns) in the brain and spinal cord. |
2023-08-26 |
2023-09-07 |
human |
| Orion P Keifer, Juanmarco Gutierrez, Mark T Butt, Sarah D Cramer, Raymond Bartus, Malu Tansey, Daniel Deaver, Alexandre Betourne, Nicholas M Bouli. Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis. PloS one. vol 18. issue 8. 2023-08-22. PMID:37607205. |
spinal cord and brain concentrations of riluzole after oral and intrathecal administration: a potential new treatment route for amyotrophic lateral sclerosis. |
2023-08-22 |
2023-09-07 |
human |
| Akiko Yamamuro-Tanabe, Yurika Mukai, Wataru Kojima, Siyuan Zheng, Naoko Matsumoto, Shoho Takada, Mao Mizuhara, Yasuhiro Kosuge, Yuki Ishimaru, Yasuhiro Yoshiok. An Increase in Peroxiredoxin 6 Expression Induces Neurotoxic A1 Astrocytes in the Lumbar Spinal Cord of Amyotrophic Lateral Sclerosis Mice Model. Neurochemical research. 2023-08-09. PMID:37556038. |
an increase in peroxiredoxin 6 expression induces neurotoxic a1 astrocytes in the lumbar spinal cord of amyotrophic lateral sclerosis mice model. |
2023-08-09 |
2023-08-16 |
mouse |
| Swetha Ramachandran, Veselin Grozdanov, Bianca Leins, Katharina Kandler, Simon Witzel, Medhanie Mulaw, Albert C Ludolph, Jochen H Weishaupt, Karin M Danze. Low T-cell reactivity to TDP-43 peptides in ALS. Frontiers in immunology. vol 14. 2023-08-07. PMID:37545536. |
dysregulation of the immune system in amyotrophic lateral sclerosis (als) includes changes in t-cells composition and infiltration of t cells in the brain and spinal cord. |
2023-08-07 |
2023-08-14 |
mouse |
| Bruno Costa Gomes, Nuno Peixinho, Rita Pisco, Marta Gromicho, Ana Catarina Pronto-Laborinho, José Rueff, Mamede de Carvalho, António Sebastião Rodrigue. Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients. Molecular neurobiology. 2023-08-02. PMID:37531027. |
amyotrophic lateral sclerosis (als) is a progressive motor neuron disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control, muscle atrophy and in later stages, death. |
2023-08-02 |
2023-08-14 |
Not clear |
| Kawaljit Kaur, Po-Chun Chen, Meng-Wei Ko, Ao Mei, Sara Huerta-Yepez, Dipnarine Maharaj, Subramaniam Malarkannan, Anahid Jewet. Successes and Challenges in Taming the Beast: Cytotoxic Immune Effectors in Amyotrophic Lateral Sclerosis. Critical reviews in immunology. vol 43. issue 1. 2023-07-31. PMID:37522557. |
amyotrophic lateral sclerosis (als) is a neurological disease characterized by the progressive loss of motor neurons in the brain and spinal cord. |
2023-07-31 |
2023-08-14 |
Not clear |
| Yu Huang, Huili Yang, Biying Yang, Yu Zheng, Xiaomei Hou, Guiling Chen, Wenqi Zhang, Xiang Zeng, Baoxin D. Ginsenoside-Rg1 combined with a conditioned medium from induced neuron-like hUCMSCs alleviated the apoptosis in a cell model of ALS through regulating the NF-κB/Bcl-2 pathway. Chinese journal of natural medicines. vol 21. issue 7. 2023-07-30. PMID:37517821. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease affecting both upper and lower motor neurons in the brain and spinal cord. |
2023-07-30 |
2023-08-14 |
human |