| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Noelle C Punessen, Claudia Pena, Alexandra Sandberg, Lilia A Koza, Daniel A Linsema. A novel anti-apoptotic role for Cdc42/ACK-1 signaling in neurons. Molecular and cellular neurosciences. 2023-06-01. PMID:37263460. |
neurodegenerative diseases such as amyotrophic lateral sclerosis, alzheimer's and parkinson's disease are caused by a progressive and aberrant destruction of neurons in the brain and spinal cord. |
2023-06-01 |
2023-08-14 |
rat |
| Hui Wang, LiPing Guan, Min Den. Recent progress of the genetics of amyotrophic lateral sclerosis and challenges of gene therapy. Frontiers in neuroscience. vol 17. 2023-05-30. PMID:37250416. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord. |
2023-05-30 |
2023-08-14 |
Not clear |
| Mohamed F Elmansy, Cory T Reidl, Mizzanoor Rahaman, P Hande Özdinler, Richard B Silverma. Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis. Medicinal research reviews. 2023-05-27. PMID:37243319. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease in which the motor neuron circuitry displays progressive degeneration, affecting mostly the motor neurons in the brain and in the spinal cord. |
2023-05-27 |
2023-08-14 |
Not clear |
| Laura López-Pingarrón, Henrique Almeida, Marisol Soria-Aznar, Marcos C Reyes-Gonzales, María Pilar Terrón, Joaquín J Garcí. Role of Oxidative Stress on the Etiology and Pathophysiology of Amyotrophic Lateral Sclerosis (ALS) and Its Relation with the Enteric Nervous System. Current issues in molecular biology. vol 45. issue 4. 2023-05-16. PMID:37185741. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease affecting motor neurons in the spinal cord, cerebral cortex, and medulla oblongata. |
2023-05-16 |
2023-08-14 |
Not clear |
| Yinrou Huang, Mengke Zhao, Xuemei Chen, Ruoyu Zhang, Anh Le, Michael Hong, Yufei Zhang, Lin Jia, Weidong Zang, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wan. Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies. Aging and disease. vol 14. issue 3. 2023-05-16. PMID:37191427. |
in this review, we summarize the biological properties of key metabolites and their pathogenic functions in 12 disorders of the central nervous system: schizophrenia, bipolar disorder, major depressive disorder, spinal cord injury, traumatic brain injury, ischemic stroke, intracerebral hemorrhage, multiple sclerosis, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, and huntington's disease. |
2023-05-16 |
2023-08-14 |
Not clear |
| Bárbara Teruel-Peña, José Luís Gómez-Urquiza, Nora Suleiman-Martos, Isabel Prieto, Francisco José García-Cózar, Manuel Ramírez-Sánchez, Carmen Fernández-Martos, Germán Domínguez-Vía. Systematic Review and Meta-Analyses of Aminopeptidases as Prognostic Biomarkers in Amyotrophic Lateral Sclerosis. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108335. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in the spinal cord, brain stem, and cerebral cortex. |
2023-04-28 |
2023-08-14 |
human |
| Christopher Q Rogers, Melissa Ramirez, Carol S Landon, Janine M DeBlasi, Andrew P Koutnik, Csilla Ari, Dominic P D'Agostin. A Glutamate Scavenging Protocol Combined with Deanna Protocol in SOD1-G93A Mouse Model of ALS. Nutrients. vol 15. issue 8. 2023-04-28. PMID:37111040. |
amyotrophic lateral sclerosis (als) is a progressive disease of neuronal degeneration in the motor cortex, brainstem, and spinal cord, resulting in impaired motor function and premature demise as a result of insufficient respiratory drive. |
2023-04-28 |
2023-08-14 |
mouse |
| Michael Punsoni, Nelli S Lakis, Michelle Mellion, Suzanne M de la Mont. Post-Polio Syndrome Revisited. Neurology international. vol 15. issue 2. 2023-04-24. PMID:37092507. |
pps afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (mnds), such as amyotrophic lateral sclerosis (als), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. |
2023-04-24 |
2023-08-14 |
Not clear |
| Ling Cao, Elizabeth N Bean, Jennifer T Malo. Preparation of Primary Mixed Glial Cell Cultures from Adult Mouse Spinal Cord Tissue. Current protocols. vol 3. issue 4. 2023-04-12. PMID:37042635. |
mixed glial cultures can be prepared from animals of different strains or post-in vivo manipulations and therefore are suitable for studying a variety of diseases/disorders that involve spinal cord pathological changes, such as amyotrophic lateral sclerosis and multiple sclerosis, as well as toxin-induced changes. |
2023-04-12 |
2023-08-14 |
mouse |
| He Jax Xu, Yao Yao, Fenyong Yao, Jiehui Chen, Meishi Li, Xianfa Yang, Sheng Li, Fangru Lu, Ping Hu, Shuijin He, Guangdun Peng, Naihe Jin. Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells. Cell regeneration (London, England). vol 12. issue 1. 2023-03-23. PMID:36949352. |
spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (als), spinal muscular atrophy (sma) and spinal cord injury (sci). |
2023-03-23 |
2023-08-14 |
human |
| Xiujuan Fu, Yizi He, Yongzhi Xie, Zuneng L. A conjoint analysis of bulk RNA-seq and single-nucleus RNA-seq for revealing the role of ferroptosis and iron metabolism in ALS. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937665. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive and selective degeneration of motor neurons in the motor cortex of brain and spinal cord. |
2023-03-20 |
2023-08-14 |
mouse |
| Francesca De Lorenzo, Patrick Lüningschrör, Jinhan Nam, Liam Beckett, Federica Pilotto, Emilia Galli, Päivi Lindholm, Cora Rüdt von Collenberg, Simon Tii Mungwa, Sibylle Jablonka, Julia Kauder, Nadine Thau-Habermann, Susanne Petri, Dan Lindholm, Smita Saxena, Michael Sendtner, Mart Saarma, Merja H Voutilaine. CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress. Brain : a journal of neurology. 2023-03-17. PMID:36928391. |
amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects motor neurons (mns) in the spinal cord, brainstem, and motor cortex, leading to paralysis and eventually to death within 3 to 5 years of symptom onset. |
2023-03-17 |
2023-08-14 |
mouse |
| Hankui Liu, Liping Guan, Min Deng, Lars Bolund, Karsten Kristiansen, Jianguo Zhang, Yonglun Luo, Zhanchi Zhan. Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration. Frontiers in neuroscience. vol 17. 2023-03-06. PMID:36875658. |
the gradual loss of motor neurons (mns) in the brain and spinal cord is a hallmark of amyotrophic lateral sclerosis (als), but the mechanisms underlying neurodegeneration in als are still not fully understood. |
2023-03-06 |
2023-08-14 |
Not clear |
| b' Maru\\xc5\\xa1a Barbo, Metka Ravnik-Glava\\xc4\\x8. Extracellular Vesicles as Potential Biomarkers in Amyotrophic Lateral Sclerosis. Genes. vol 14. issue 2. 2023-02-25. PMID:36833252.' |
amyotrophic lateral sclerosis (als) is described as a fatal and rapidly progressive neurodegenerative disorder caused by the degeneration of upper motor neurons in the primary motor cortex and lower motor neurons of the brainstem and spinal cord. |
2023-02-25 |
2023-08-14 |
Not clear |
| Yousra El Ouaamari, Jasper Van den Bos, Barbara Willekens, Nathalie Cools, Inez Wen. Neurotrophic Factors as Regenerative Therapy for Neurodegenerative Diseases: Current Status, Challenges and Future Perspectives. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835277. |
neurodegenerative diseases, including alzheimer's disease (ad), parkinson's disease (pd), huntington's disease (hd), multiple sclerosis (ms), spinal cord injury (sci), and amyotrophic lateral sclerosis (als), are characterized by acute or chronic progressive loss of one or several neuronal subtypes. |
2023-02-25 |
2023-08-14 |
Not clear |
| Yaning Zang, Xigui Lai, Conghui Li, Dongfang Ding, Ying Wang, Yi Zh. The Role of Gut Microbiota in Various Neurological and Psychiatric Disorders-An Evidence Mapping Based on Quantified Evidence. Mediators of inflammation. vol 2023. 2023-02-23. PMID:36816743. |
we searched for neurological diseases and psychiatric disorders, including alzheimer's disease (ad), attention deficit hyperactivity disorder (adhd), amyotrophic lateral sclerosis (als), autism spectrum disorder (asd), anorexia nervosa (an), bipolar disorder (bd), eating disorder (ed), generalized anxiety disorder (gad), major depressive disorder (mdd), multiple sclerosis (ms), obsessive compulsive disorder (ocd), parkinson's disease (pd), posttraumatic stress disorder (ptsd), spinal cord injury (sci), schizophrenia, and stroke. |
2023-02-23 |
2023-08-14 |
Not clear |
| Yoshitaka Tamaki, Jay P Ross, Paria Alipour, Charles-Étienne Castonguay, Boting Li, Helene Catoire, Daniel Rochefort, Makoto Urushitani, Ryosuke Takahashi, Joshua A Sonnen, Stefano Stifani, Patrick A Dion, Guy A Roulea. Spinal cord extracts of amyotrophic lateral sclerosis spread TDP-43 pathology in cerebral organoids. PLoS genetics. vol 19. issue 2. 2023-02-06. PMID:36745687. |
spinal cord extracts of amyotrophic lateral sclerosis spread tdp-43 pathology in cerebral organoids. |
2023-02-06 |
2023-08-14 |
human |
| Deepti Katiyar, Shipra Singhal, Priya Bansal, K Nagarajan, Parul Grove. Nutraceuticals and phytotherapeutics for holistic management of amyotrophic lateral sclerosis. 3 Biotech. vol 13. issue 2. 2023-01-30. PMID:36714551. |
amyotrophic lateral sclerosis" (als) is a progressive neuronal disorder that affects sensory neurons in the brain and spinal cord, causing loss of muscle control. |
2023-01-30 |
2023-08-14 |
Not clear |
| Ceri Houldsworth, Krishnan Padmakumari Sivaraman Nair, Ram Pankajam Harihara. Cognition and Quality of Life of People with Spinal Cord Injury. Progress in rehabilitation medicine. vol 8. 2023-01-27. PMID:36703799. |
the aim of this study was to assess the cognitive abilities of people with spinal cord injury (sci) using the edinburgh cognitive and behavior amyotrophic lateral sclerosis screen (ecas), a tool designed for testing cognition in individuals with limited hand motor function. |
2023-01-27 |
2023-08-14 |
Not clear |
| Elisa Duranti, Chiara Vill. Molecular Investigations of Protein Aggregation in the Pathogenesis of Amyotrophic Lateral Sclerosis. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614144. |
amyotrophic lateral sclerosis (als) is a devastating progressive neurodegenerative disorder characterized by selective loss of lower and upper motor neurons (mns) in the brain and spinal cord, resulting in paralysis and eventually death due to respiratory insufficiency. |
2023-01-08 |
2023-08-14 |
Not clear |