| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Li, Jian-Xiu Wang, Zhong-He Zhou, Yao Lu, Xiao-Qiu Li, Bao-Jun Liu, Hui-Sheng Che. Contribution of capsaicin-sensitive primary afferents to mechanical hyperalgesia induced by ventral root transection in rats: the possible role of BDNF. Neurological research. vol 38. issue 1. 2017-01-12. PMID:27078694. |
capsaicin stimulation of afferent fibres was also shown to result in the release of bdnf into the spinal cord. |
2017-01-12 |
2023-08-13 |
rat |
| José Antonio-Santos, Diórginis José S Ferreira, Gizelle L Gomes Costa, Rhowena Jane B Matos, Ana E Toscano, Raul Manhães-de-Castro, Carol G Leandr. Resistance Training Alters the Proportion of Skeletal Muscle Fibers but Not Brain Neurotrophic Factors in Young Adult Rats. Journal of strength and conditioning research. vol 30. issue 12. 2016-12-22. PMID:27870699. |
spinal cord, motor cortex, and cerebellum were removed for rt-pcr analysis of bdnf and insulin-like growth factor-1 (igf-1) gene expression. |
2016-12-22 |
2023-08-13 |
rat |
| Hyo-jin Chung, Wook-hun Chung, Jae-Hoon Lee, Dai-Jung Chung, Wo-Jong Yang, A-Jin Lee, Chi-Bong Choi, Hwa-Seok Chang, Dae-Hyun Kim, Hyun Jung Suh, Dong-Hun Lee, Soo-Han Hwang, Sun Hee Do, Hwi-Yool Ki. Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats. Journal of veterinary science. vol 17. issue 1. 2016-12-13. PMID:27051345. |
quantitative elisa of extract from entire injured spinal cord showed increased expression of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf) and neurotrophin-3 (nt-3). |
2016-12-13 |
2023-08-13 |
human |
| Hyo-jin Chung, Wook-hun Chung, Jae-Hoon Lee, Dai-Jung Chung, Wo-Jong Yang, A-Jin Lee, Chi-Bong Choi, Hwa-Seok Chang, Dae-Hyun Kim, Hyun Jung Suh, Dong-Hun Lee, Soo-Han Hwang, Sun Hee Do, Hwi-Yool Ki. Expression of neurotrophic factors in injured spinal cord after transplantation of human-umbilical cord blood stem cells in rats. Journal of veterinary science. vol 17. issue 1. 2016-12-13. PMID:27051345. |
our results show that treatment of sci with hucb-mscs can improve locomotor functions, and suggest that increased levels of bdnf, ngf and nt-3 in the injured spinal cord were the main therapeutic effect. |
2016-12-13 |
2023-08-13 |
human |
| Hyo Young Jung, Dae Won Kim, Hee Sun Yim, Dae Young Yoo, Jong Whi Kim, Moo-Ho Won, Yeo Sung Yoon, Soo Young Choi, In Koo Hwan. Heme Oxygenase-1 Protects Neurons from Ischemic Damage by Upregulating Expression of Cu,Zn-Superoxide Dismutase, Catalase, and Brain-Derived Neurotrophic Factor in the Rabbit Spinal Cord. Neurochemical research. vol 41. issue 4. 2016-11-10. PMID:26559686. |
animals were sacrificed 15 min after reperfusion to measure lactate levels; 24 h after reperfusion to measure caspase 3 and myeloperoxidase levels, lipid peroxidation, and the activity of cu,zn-superoxide dismutase (sod1) and catalase (cat); or 72 h after reperfusion to assess neuronal survival and measure the levels of brain-derived neurotrophic factor (bdnf) in spinal cord homogenates. |
2016-11-10 |
2023-08-13 |
rabbit |
| Hyo Young Jung, Dae Won Kim, Hee Sun Yim, Dae Young Yoo, Jong Whi Kim, Moo-Ho Won, Yeo Sung Yoon, Soo Young Choi, In Koo Hwan. Heme Oxygenase-1 Protects Neurons from Ischemic Damage by Upregulating Expression of Cu,Zn-Superoxide Dismutase, Catalase, and Brain-Derived Neurotrophic Factor in the Rabbit Spinal Cord. Neurochemical research. vol 41. issue 4. 2016-11-10. PMID:26559686. |
pep-1-ho-1 administration significantly mitigated the decrease in sod1 and cat 24 h after reperfusion, and reversed the decrease in bdnf levels in spinal cord homogenates 72 h after ischemia/reperfusion. |
2016-11-10 |
2023-08-13 |
rabbit |
| Zhi-Yin Lou, Wen-Bo Yu, Jie Chen, Lin Li, Li-Sheng Jiang, Bao-Guo Xiao, Zhen-Guo Li. Neuroprotective Effect Is Driven Through the Upregulation of CB1 Receptor in Experimental Autoimmune Encephalomyelitis. Journal of molecular neuroscience : MN. vol 58. issue 2. 2016-11-08. PMID:26411568. |
interestingly, overexpression of cb1r dramatically enhanced the expression of neurotrophic nt-3, bdnf, and gdnf in the spinal cord. |
2016-11-08 |
2023-08-13 |
mouse |
| Jennifer Butenschön, Tina Zimmermann, Nikolai Schmarowski, Robert Nitsch, Barbara Fackelmeier, Kevin Friedemann, Konstantin Radyushkin, Jan Baumgart, Beat Lutz, Julia Leschi. PSA-NCAM positive neural progenitors stably expressing BDNF promote functional recovery in a mouse model of spinal cord injury. Stem cell research & therapy. vol 7. 2016-10-18. PMID:26762640. |
psa-ncam positive neural progenitors stably expressing bdnf promote functional recovery in a mouse model of spinal cord injury. |
2016-10-18 |
2023-08-13 |
mouse |
| Waleed M Renno, Khalid M Khan, Ludmil Beno. Is there a role for neurotrophic factors and their receptors in augmenting the neuroprotective effect of (-)-epigallocatechin-3-gallate treatment of sciatic nerve crush injury? Neuropharmacology. vol 102. 2016-10-07. PMID:26514400. |
analysis of bdnf, gdnf and nt3 neurotropic factors and trk-b, trk-c and ngfr-p75 receptors in neurons in the spinal cord of crush and crush + eggc rats showed significant (p < 0.0001) decrease compared to naÏve and sham at day 1, 3, 7 and 14 after nerve injury. |
2016-10-07 |
2023-08-13 |
rat |
| Waleed M Renno, Khalid M Khan, Ludmil Beno. Is there a role for neurotrophic factors and their receptors in augmenting the neuroprotective effect of (-)-epigallocatechin-3-gallate treatment of sciatic nerve crush injury? Neuropharmacology. vol 102. 2016-10-07. PMID:26514400. |
egcg treatment significantly (p < 0.0001) increased the bdnf, gdn, nt3, trk-b, trk-c and ngfr-p75 immunostaining in the l3-l6 spinal cord compared to crush animals. |
2016-10-07 |
2023-08-13 |
rat |
| Gaby J Ritfeld, Ajay Patel, Alexander Chou, Tabitha L Novosat, Deborah G Castillo, Raymund A C Roos, Martin Oudeg. The role of brain-derived neurotrophic factor in bone marrow stromal cell-mediated spinal cord repair. Cell transplantation. vol 24. issue 11. 2016-10-06. PMID:25581479. |
together, our data broaden our understanding of the role of bdnf in bmsc-mediated neuroprotection and successfully exploit bdnf dependency to enhance anatomical spinal cord repair. |
2016-10-06 |
2023-08-13 |
rat |
| Snehlata Samberkar, Sivasangkary Gandhi, Murali Naidu, Kah-Hui Wong, Jegadeesh Raman, Vikineswary Sabaratna. Lion's Mane, Hericium erinaceus and Tiger Milk, Lignosus rhinocerotis (Higher Basidiomycetes) Medicinal Mushrooms Stimulate Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina: An In Vitro Study. International journal of medicinal mushrooms. vol 17. issue 11. 2016-10-06. PMID:26853959. |
the aim of this study was to investigate the potential of h. erinaceus and l. rhinocerotis to stimulate neurite outgrowth in dissociated cells of brain, spinal cord, and retina from chick embryo when compared to brain derived neurotrophic factor (bdnf). |
2016-10-06 |
2023-08-13 |
chicken |
| Sun-Young Jung, Tae-Beom Seo, Dae-Young Ki. Treadmill exercise facilitates recovery of locomotor function through axonal regeneration following spinal cord injury in rats. Journal of exercise rehabilitation. vol 12. issue 4. 2016-09-22. PMID:27656624. |
we examined bdnf expression and axonal sprouting in the injury site of the spinal cord using western blot analysis and immunofluorescence staining. |
2016-09-22 |
2023-08-13 |
rat |
| Wei Yang, Hao Zhan. Effects of hindlimb unloading on neurotrophins in the rat spinal cord and soleus muscle. Brain research. vol 1630. 2016-09-19. PMID:26529644. |
the aim of the present study was to investigate the effects of hindlimb unloading (hu) on the expression of neurotrophin-3 (nt-3) and brain-derived neurotrophic factor (bdnf), together with the expression of their high-affinity receptors tropomyosin receptor kinase c (trkc) and tropomyosin receptor kinase b (trkb), in lumbar (l4-6) segment of the spinal cord and in the soleus muscle. |
2016-09-19 |
2023-08-13 |
rat |
| Wei Yang, Hao Zhan. Effects of hindlimb unloading on neurotrophins in the rat spinal cord and soleus muscle. Brain research. vol 1630. 2016-09-19. PMID:26529644. |
in this study, nt-3 and bdnf mrna and protein expression were significantly increased in the spinal cord and soleus muscle after hu. |
2016-09-19 |
2023-08-13 |
rat |
| Zheng-guang Xu, Jun Yang, Zhi-ping Lv, Ting-hua Wang, Xiao-song Li, Jiang-hua Liu, Nan Zhao, Yan-bin Xiyan. [Effect of Herba Lycopodii Alcohol Extracted Granule Combined Methylprednisolone on Expression Levels of BDNF and NMDA and Behavior of Traumatic Spinal Cord Injury Rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 35. issue 8. 2016-09-15. PMID:26485919. |
[effect of herba lycopodii alcohol extracted granule combined methylprednisolone on expression levels of bdnf and nmda and behavior of traumatic spinal cord injury rats]. |
2016-09-15 |
2023-08-13 |
rat |
| Zheng-guang Xu, Jun Yang, Zhi-ping Lv, Ting-hua Wang, Xiao-song Li, Jiang-hua Liu, Nan Zhao, Yan-bin Xiyan. [Effect of Herba Lycopodii Alcohol Extracted Granule Combined Methylprednisolone on Expression Levels of BDNF and NMDA and Behavior of Traumatic Spinal Cord Injury Rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 35. issue 8. 2016-09-15. PMID:26485919. |
to study different effects of herba lycopodii (hl) alcohol extracted granule combined methylprednisolone on behavioral changes, brain derived neurotrophic factor (bdnf) expression levels, and n-methyl-d-aspartate (nmda) receptor levels in rats with spinal cord injury (sci). |
2016-09-15 |
2023-08-13 |
rat |
| Jin-Wei Yang, Jin Ru, Wei Ma, Yan Gao, Zhang Liang, Jia Liu, Jian-Hui Guo, Li-Yan L. BDNF promotes the growth of human neurons through crosstalk with the Wnt/β-catenin signaling pathway via GSK-3β. Neuropeptides. vol 54. 2016-09-13. PMID:26311646. |
in this study, we investigated whether bdnf exerts its neurotrophic effects through the wnt/β-catenin signaling pathway in human embryonic spinal cord neurons in vitro. |
2016-09-13 |
2023-08-13 |
human |
| Saïd M'Dahoma, Sandrine Barthélemy, Claire Tromilin, Tiffany Jeanson, Florent Viguier, Benoit Michot, Sophie Pezet, Michel Hamon, Sylvie Bourgoi. Respective pharmacological features of neuropathic-like pain evoked by intrathecal BDNF versus sciatic nerve ligation in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26343858. |
marked induction of microglia activation markers (ox42, iba1, p-p38), proinflammatory cytokine il-6, nmda receptor subunit nr2b and bdnf was found in spinal cord and/or dorsal root ganglia of cci-sn rats. |
2016-08-26 |
2023-08-13 |
rat |
| Manuel Ingo Günther, Norbert Weidner, Rainer Müller, Armin Blesc. Cell-seeded alginate hydrogel scaffolds promote directed linear axonal regeneration in the injured rat spinal cord. Acta biomaterialia. vol 27. 2016-08-04. PMID:26348141. |
to determine whether regenerating axons can be guided in rostrocaudal direction, we implanted 2mm long alginate-based anisotropic capillary hydrogels seeded with bone marrow stromal cells (bmscs) expressing brain-derived neurotrophic factor (bdnf) or green fluorescent protein (gfp) as control into a c5 hemisection lesion of the rat spinal cord. |
2016-08-04 |
2023-08-13 |
rat |