| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Goto, S Furukaw. [Experimental changes in BDNF- and NT-3-like immunoreactivities in the spinal cord following its transection]. Nihon Seikeigeka Gakkai zasshi. vol 69. issue 7. 1995-11-08. PMID:7561352. |
in the gray matter at 4 weeks after injury, astrocyte-like cells were markedly stained with anti-bdnf antibodies these findings indicate that in the spinal cord after injury, the biosynthesis of bdnf was upregulated in a different manner from that of nt-3 and that bdnf and nt-3 were both involved in the repair mechanisms, directing the amelioration of the spinal cord injury. |
1995-11-08 |
2023-08-12 |
rat |
| X M Xu, V Guénard, N Kleitman, P Aebischer, M B Bung. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Experimental neurology. vol 134. issue 2. 1995-10-26. PMID:7556546. |
a combination of bdnf and nt-3 promotes supraspinal axonal regeneration into schwann cell grafts in adult rat thoracic spinal cord. |
1995-10-26 |
2023-08-12 |
rat |
| X M Xu, V Guénard, N Kleitman, P Aebischer, M B Bung. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Experimental neurology. vol 134. issue 2. 1995-10-26. PMID:7556546. |
our results clearly demonstrate that bdnf and nt-3 infusion enhanced propriospinal axonal regeneration and, more significantly, promoted axonal regeneration of specific distant populations of brain stem neurons into grafts at the mid-thoracic level in adult rat spinal cord. |
1995-10-26 |
2023-08-12 |
rat |
| J A Siuciak, V Wong, D Pearsall, S J Wiegand, R M Lindsa. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. The European journal of neuroscience. vol 7. issue 4. 1995-08-30. PMID:7620617. |
bdnf produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. |
1995-08-30 |
2023-08-12 |
rat |
| J A Siuciak, V Wong, D Pearsall, S J Wiegand, R M Lindsa. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. The European journal of neuroscience. vol 7. issue 4. 1995-08-30. PMID:7620617. |
as our previous studies showed that bdnf-induced analgesia was reversible by naloxone, we have examined the effects of bdnf administration on brain and spinal cord levels of neuropeptides involved in the modulation of nociceptive information, including the endogenous opioid peptides, met-enkephalin and beta-endorphin, as well as substance p and neuropeptide y (npy). |
1995-08-30 |
2023-08-12 |
rat |
| J A Siuciak, V Wong, D Pearsall, S J Wiegand, R M Lindsa. BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception. The European journal of neuroscience. vol 7. issue 4. 1995-08-30. PMID:7620617. |
these studies demonstrate a modulatory effect of bdnf on relevant neuropeptides within areas of the brain and spinal cord involved in the processing of nociceptive information. |
1995-08-30 |
2023-08-12 |
rat |
| A C Kato, R M Lindsa. Overlapping and additive effects of neurotrophins and CNTF on cultured human spinal cord neurons. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867750. |
to explore the potential use of these and other neurotrophic factors as therapeutic agents in human motoneuron diseases, we have examined the effects of the neurotrophins ngf, bdnf, neurotrophin-3 (nt-3), and neurotrophin-4/5 (nt-4/5) and the cytokines cntf and cholinergic differentiation factor/leukemia inhibitory factor (cdf/lif) and combinations of these factors on fetal human spinal cord neurons grown for 7-10 days in monolayer cultures. |
1995-03-27 |
2023-08-12 |
rat |
| P S Diener, B S Bregma. Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats. Neuroreport. vol 5. issue 15. 1995-03-06. PMID:7841375. |
after spinal cord hemisection in newborn rats, the exogenous administration of neurotrophic factors brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) and nerve growth factor (ngf), prevents the retrograde cell death of axotomized red nucleus neurons (and other brain stem spinal neurons) in vivo. |
1995-03-06 |
2023-08-12 |
rat |
| R E Clatterbuck, D L Price, V E Koliatso. Further characterization of the effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on axotomized neonatal and adult mammalian motor neurons. The Journal of comparative neurology. vol 342. issue 1. 1994-07-12. PMID:7515907. |
in addition, bdnf is transported retrogradely to alpha-motor neurons following injection into the muscle, and patterns of bdnf expressed in spinal cord and muscle suggest a physiological role for this factor in motor neurons. |
1994-07-12 |
2023-08-12 |
Not clear |
| J A Siuciak, C A Altar, S J Wiegand, R M Lindsa. Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3. Brain research. vol 633. issue 1-2. 1994-04-25. PMID:7511037. |
the antinociceptive effect of bdnf infusion was accompanied by an augmentation in serotonergic activity within the brain and spinal cord. |
1994-04-25 |
2023-08-12 |
rat |
| L Schnell, R Schneider, R Kolbeck, Y A Barde, M E Schwa. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature. vol 367. issue 6459. 1994-03-30. PMID:8114912. |
here we study the effects of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) on the largest tract system leading from the brain to the spinal cord, the corticospinal tract (cst). |
1994-03-30 |
2023-08-12 |
rat |
| L Schnell, R Schneider, R Kolbeck, Y A Barde, M E Schwa. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature. vol 367. issue 6459. 1994-03-30. PMID:8114912. |
in adult rats, injection of nt-3 (but not bdnf) into the lesioned spinal cord increases the regenerative sprouting of the transected cst. |
1994-03-30 |
2023-08-12 |
rat |