| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H A Vische. BDNF is expressed at the crush site after spinal cord lesion in newborn opossum (Monodelphis domestica). The European journal of neuroscience. vol 9. issue 9. 1997-12-23. PMID:9383223. |
this suggests that bdnf plays a role in the repair of lesioned neonatal spinal cord. |
1997-12-23 |
2023-08-12 |
chicken |
| G J Michael, S Averill, A Nitkunan, M Rattray, D L Bennett, Q Yan, J V Priestle. Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334420. |
the central transport resulted in bdnf immunoreactivity in cgrp containing terminal arbors in the dorsal horn of the spinal cord, and this immunoreactivity was increased by ngf treatment. |
1997-11-20 |
2023-08-12 |
rat |
| M Shinoda, B J Hoffer, L Olso. Minor immunoreactivity in GDNF-, BDNF-, or NT-3-treated substantia nigra allografts. Journal of neural transplantation & plasticity. vol 6. issue 2. 1997-11-04. PMID:9306240. |
together with our previous finding that gdnf treatment of spinal cord transplants activates immune responses and leads to microglial activation, our data demonstrate that although treatment with gdnf and to some degree with bdnf can enhance immune responses to immunogenic grafts, such as fetal spinal cord grafts, but the trophic factors per se do not elicit any marked response in non-immunogenic grafts like substantia nigra. |
1997-11-04 |
2023-08-12 |
rat |
| H J Cho, J K Kim, X F Zhou, R A Rus. Increased brain-derived neurotrophic factor immunoreactivity in rat dorsal root ganglia and spinal cord following peripheral inflammation. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295223. |
in the present study, we evaluated the change of bdnf immunoreactivity in the drg and spinal cord following peripheral inflammation by means of immunohistochemistry. |
1997-10-23 |
2023-08-12 |
rat |
| K Yang, X S Mu, R L Hayes, Y H Qiu, F L Sorgi, L Huang, G L Clifto. DC-Chol liposome-mediated gene transfer in rat spinal cord. Neuroreport. vol 8. issue 9-10. 1997-10-07. PMID:9243639. |
reporter gene (beta-gal) or brain-derived neurotrophic factor (bdnf) cdna containing a pcmv promoter complexed with dc-chol liposomes was injected into the intact rat spinal cord gray matter. |
1997-10-07 |
2023-08-12 |
rat |
| A Kishino, Y Ishige, T Tatsuno, C Nakayama, H Noguch. BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Experimental neurology. vol 144. issue 2. 1997-06-19. PMID:9168829. |
these results provide a rationale for bdnf treatment in motor neuron diseases such as spinal cord injury and amyotrophic lateral sclerosis. |
1997-06-19 |
2023-08-12 |
rat |
| D H Kim, P H Gutin, L J Noble, D Nathan, J S Yu, R P Nockel. Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat. Neuroreport. vol 7. issue 13. 1997-03-28. PMID:8930993. |
treatment with genetically engineered fibroblasts producing ngf or bdnf can accelerate recovery from traumatic spinal cord injury in the adult rat. |
1997-03-28 |
2023-08-12 |
rat |
| D H Kim, P H Gutin, L J Noble, D Nathan, J S Yu, R P Nockel. Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat. Neuroreport. vol 7. issue 13. 1997-03-28. PMID:8930993. |
we tested the hypothesis that ngf or bdnf can protect damaged neural structures following spinal cord injury. |
1997-03-28 |
2023-08-12 |
rat |
| D H Kim, P H Gutin, L J Noble, D Nathan, J S Yu, R P Nockel. Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat. Neuroreport. vol 7. issue 13. 1997-03-28. PMID:8930993. |
histological examination after 6 weeks showed a larger cross-sectional area of spinal cord at the maximal injury site in the animals treated with ngf or bdnf. |
1997-03-28 |
2023-08-12 |
rat |
| J H Ye, J D Houl. Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. Experimental neurology. vol 143. issue 1. 1997-02-28. PMID:9000447. |
four weeks after spinal cord injury, gel foam saturated with brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt-3), ciliary neurotrophic factor (cntf), or saline as a control was placed into the lesion cavity. |
1997-02-28 |
2023-08-12 |
Not clear |
| D L Bennett, J French, J V Priestley, S B McMaho. NGF but not NT-3 or BDNF prevents the A fiber sprouting into lamina II of the spinal cord that occurs following axotomy. Molecular and cellular neurosciences. vol 8. issue 4. 1997-02-20. PMID:9000437. |
ngf but not nt-3 or bdnf prevents the a fiber sprouting into lamina ii of the spinal cord that occurs following axotomy. |
1997-02-20 |
2023-08-12 |
rat |
| M Yamamoto, G Sobue, K Yamamoto, S Terao, T Mitsum. Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues. Neurochemical research. vol 21. issue 8. 1997-02-18. PMID:8895847. |
ngf and bdnf mrna levels were high in the heart and spleen as well as in the dorsal root ganglia (drg) and spinal cord, showing similar spatial expression patterns, while nt-3 mrna levels were more pronounced in the liver and spleen. |
1997-02-18 |
2023-08-12 |
human |
| M Shinoda, B J Hoffer, L Olso. Interactions of neurotrophic factors GDNF and NT-3, but not BDNF, with the immune system following fetal spinal cord transplantation. Brain research. vol 722. issue 1-2. 1996-12-18. PMID:8813361. |
interactions of neurotrophic factors gdnf and nt-3, but not bdnf, with the immune system following fetal spinal cord transplantation. |
1996-12-18 |
2023-08-12 |
rat |
| F Dittrich, G Ochs, A Grosse-Wilde, U Berweiler, Q Yan, J A Miller, K V Toyka, M Sendtne. Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons. Experimental neurology. vol 141. issue 2. 1996-11-27. PMID:8812156. |
previous studies have demonstrated little or no penetration of the blood-brain barrier by bdnf, hence systemic application does not result in significant penetration into the spinal cord to produce direct action on motoneurons. |
1996-11-27 |
2023-08-12 |
Not clear |
| S Braun, B Croizat, M C Lagrange, J M Warter, P Poindro. Neurotrophins increase motoneurons' ability to innervate skeletal muscle fibers in rat spinal cord--human muscle cocultures. Journal of the neurological sciences. vol 136. issue 1-2. 1996-10-04. PMID:8815167. |
neurotrophins, nerve growth factor (ngf), neurotrophin-3 (nt-3), neurotrophin-5 (nt-5) and brain-derived neurotrophic factor (bdnf), were studied in vitro in a coculture model of human skeletal muscle myotubes and rat embryo spinal cord explants, which enables the different steps of functional innervation to be followed, including neurite outgrowth, synapse formation and induction of contractile activity. |
1996-10-04 |
2023-08-12 |
human |
| S Braun, B Croizat, M C Lagrange, J M Warter, P Poindro. Neurotrophins increase motoneurons' ability to innervate skeletal muscle fibers in rat spinal cord--human muscle cocultures. Journal of the neurological sciences. vol 136. issue 1-2. 1996-10-04. PMID:8815167. |
we found that nt-3, nt-5, bdnf, but not ngf simultaneously induced a significant increase in the number and length of neurites emerging from spinal cord explants, the number of endplates per muscle fiber, and the area of innervated muscle fibers around each spinal cord explant. |
1996-10-04 |
2023-08-12 |
human |
| S Braun, B Croizat, M C Lagrange, J M Warter, P Poindro. Neurotrophins increase motoneurons' ability to innervate skeletal muscle fibers in rat spinal cord--human muscle cocultures. Journal of the neurological sciences. vol 136. issue 1-2. 1996-10-04. PMID:8815167. |
these results suggest that neurotrophins nt-3, nt-5 and bdnf enhance spinal cord motoneurons potential of innervation. |
1996-10-04 |
2023-08-12 |
human |
| Y Nakahara, F H Gage, M H Tuszynsk. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell transplantation. vol 5. issue 2. 1996-08-27. PMID:8689031. |
grafts of fibroblasts genetically modified to secrete ngf, bdnf, nt-3, or basic fgf elicit differential responses in the adult spinal cord. |
1996-08-27 |
2023-08-12 |
rat |
| Y Nakahara, F H Gage, M H Tuszynsk. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell transplantation. vol 5. issue 2. 1996-08-27. PMID:8689031. |
we genetically modified primary rat fibroblasts to produce either nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), or basic fibroblast growth factor (bfgf), then grafted these neurotrophic factor-secreting cells into the central gray matter of the spinal cord in adult rats. |
1996-08-27 |
2023-08-12 |
rat |
| K A Huber, K Krieglstein, K Unsicke. The neurotrophins BDNF, NT-3 and -4, but not NGF, TGF-beta 1 and GDNF, increase the number of NADPH-diaphorase-reactive neurons in rat spinal cord cultures. Neuroscience. vol 69. issue 3. 1996-04-18. PMID:8596647. |
the neurotrophins bdnf, nt-3 and -4, but not ngf, tgf-beta 1 and gdnf, increase the number of nadph-diaphorase-reactive neurons in rat spinal cord cultures. |
1996-04-18 |
2023-08-12 |
rat |