| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L B Jakeman, P Wei, Z Guan, B T Stoke. Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. Experimental neurology. vol 154. issue 1. 1999-01-19. PMID:9875278. |
based on immunohistochemical detection of bdnf protein distribution, these described effects are likely to be mediated by the activation of cells and axons within the central injury region and the along the peripheral rim of the spinal cord. |
1999-01-19 |
2023-08-12 |
rat |
| H J Cho, J K Kim, H C Park, J K Kim, D S Kim, S O Ha, H S Hon. Changes in brain-derived neurotrophic factor immunoreactivity in rat dorsal root ganglia, spinal cord, and gracile nuclei following cut or crush injuries. Experimental neurology. vol 154. issue 1. 1999-01-19. PMID:9875283. |
in the present study, we evaluated changes in brain-derived neurotrophic factor (bdnf) immunoreactivity in the rat lumbar (l) 5 dorsal root ganglion (drg) and areas where afferents from the drg terminate, the l5 spinal cord and gracile nuclei, following unilateral sciatic nerve transection or crush. |
1999-01-19 |
2023-08-12 |
rat |
| H J Cho, J K Kim, H C Park, J K Kim, D S Kim, S O Ha, H S Hon. Changes in brain-derived neurotrophic factor immunoreactivity in rat dorsal root ganglia, spinal cord, and gracile nuclei following cut or crush injuries. Experimental neurology. vol 154. issue 1. 1999-01-19. PMID:9875283. |
these differences in bdnf response in the drg and spinal cord after cut or crush injuries may reflect differences in trophic support to the injured drg neurons and altered neuronal activity in the spinal cord and gracile nuclei following different types of peripheral nerve injury. |
1999-01-19 |
2023-08-12 |
rat |
| H S Sharma, F Nyberg, J Westman, P Alm, T Gordh, D Lindhol. Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat. Amino acids. vol 14. issue 1-3. 1999-01-13. PMID:9871451. |
the possibility that brain derived neurotrophic factor (bdnf) and insulin like growth factor-1 (igf) induced neuroprotection is influenced by mechanisms involving nitric oxide was examined in a rat model of focal spinal cord injury. |
1999-01-13 |
2023-08-12 |
rat |
| H S Sharma, F Nyberg, J Westman, P Alm, T Gordh, D Lindhol. Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat. Amino acids. vol 14. issue 1-3. 1999-01-13. PMID:9871451. |
bdnf or igf-i (0.1 microgram/10 microliters in phosphate buffer saline) was applied topically 30 min before injury on the exposed spinal cord followed by repeated doses of growth factors immediately before and 30 min after injury. |
1999-01-13 |
2023-08-12 |
rat |
| H S Sharma, F Nyberg, J Westman, P Alm, T Gordh, D Lindhol. Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat. Amino acids. vol 14. issue 1-3. 1999-01-13. PMID:9871451. |
pretreatment with bdnf and igf significantly reduced the upregulation of nnos in the spinal cord. |
1999-01-13 |
2023-08-12 |
rat |
| H S Sharma, F Nyberg, J Westman, P Alm, T Gordh, D Lindhol. Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat. Amino acids. vol 14. issue 1-3. 1999-01-13. PMID:9871451. |
these results suggest that bdnf and igf pretreatment is neuroprotective in spinal cord injury and that these neurotrophic factors have the capacity to down regulate nnos expression following trauma to the spinal cord. |
1999-01-13 |
2023-08-12 |
rat |
| B Li, Z Wang, P Zh. [Changes of BDNF mRNA by molecular hybridization during embryonic spinal cord repairing injury of adult rats]. Zhonghua yi xue za zhi. vol 77. issue 7. 1998-11-06. PMID:9772453. |
[changes of bdnf mrna by molecular hybridization during embryonic spinal cord repairing injury of adult rats]. |
1998-11-06 |
2023-08-12 |
rat |
| B Li, Z Wang, P Zh. [Changes of BDNF mRNA by molecular hybridization during embryonic spinal cord repairing injury of adult rats]. Zhonghua yi xue za zhi. vol 77. issue 7. 1998-11-06. PMID:9772453. |
to study the changes of (brain-derived neurotrophic factor) bdnf mrna during embroyonic spinal cord repairing spinal cord injury of adult rats. |
1998-11-06 |
2023-08-12 |
rat |
| D A Houweling, J T van Asseldonk, A J Lankhorst, F P Hamers, D Martin, P R Bär, E A Jooste. Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat. Neuroscience letters. vol 251. issue 3. 1998-10-30. PMID:9726376. |
we studied the effect of local application of brain-derived neurotrophic factor (bdnf) on functional recovery after dorsal spinal cord transection in the adult rat. |
1998-10-30 |
2023-08-12 |
rat |
| D A Houweling, J T van Asseldonk, A J Lankhorst, F P Hamers, D Martin, P R Bär, E A Jooste. Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat. Neuroscience letters. vol 251. issue 3. 1998-10-30. PMID:9726376. |
the results indicate that local application of bdnf results in a decreased loss of function in the partially transected rat spinal cord starting one day after injury. |
1998-10-30 |
2023-08-12 |
rat |
| P Menei, C Montero-Menei, S R Whittemore, R P Bunge, M B Bung. Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. The European journal of neuroscience. vol 10. issue 2. 1998-10-22. PMID:9749723. |
schwann cells genetically modified to secrete human bdnf promote enhanced axonal regrowth across transected adult rat spinal cord. |
1998-10-22 |
2023-08-12 |
human |
| P Menei, C Montero-Menei, S R Whittemore, R P Bunge, M B Bung. Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. The European journal of neuroscience. vol 10. issue 2. 1998-10-22. PMID:9749723. |
the infusion of bdnf and nt-3 into schwann cell (sc) grafts promotes regeneration of brainstem neurones into the grafts placed in adult rat spinal cord transected at t8 (xu et al., 1995b). |
1998-10-22 |
2023-08-12 |
human |
| S T Sayers, N Khan, Y Ahmed, R Shahid, T Kha. Preparation of brain-derived neurotrophic factor- and neurotrophin-3-secreting Schwann cells by infection with a retroviral vector. Journal of molecular neuroscience : MN. vol 10. issue 2. 1998-10-20. PMID:9699155. |
recent studies have shown that the application of brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) acts to encourage the regrowth of motor and sensory fibers after spinal cord injury. |
1998-10-20 |
2023-08-12 |
human |
| Y Kawamoto, S Nakamura, I Akiguchi, J Kimur. Immunohistochemical localization of brain-derived neurotrophic factor in the spinal cords of amyotrophic lateral sclerosis and non-amyotrophic lateral sclerosis patients. Journal of neuropathology and experimental neurology. vol 57. issue 9. 1998-09-25. PMID:9737545. |
to localize and assess bdnf in the human spinal cord with particular reference to amyotrophic lateral sclerosis (als), we immunohistochemically studied spinal cords from 8 als and 13 non-als patients. |
1998-09-25 |
2023-08-12 |
human |
| Y Kawamoto, S Nakamura, I Akiguchi, J Kimur. Immunohistochemical localization of brain-derived neurotrophic factor in the spinal cords of amyotrophic lateral sclerosis and non-amyotrophic lateral sclerosis patients. Journal of neuropathology and experimental neurology. vol 57. issue 9. 1998-09-25. PMID:9737545. |
the results suggest that bdnf may act widely as a trophic factor in the human spinal cord, and motor neurons in als patients might be sufficiently supplied with endogenous bdnf from other neuronal subpopulations in the spinal cord. |
1998-09-25 |
2023-08-12 |
human |
| D M McTigue, P J Horner, B T Stokes, F H Gag. Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 14. 1998-07-27. PMID:9651218. |
in this study, fibroblasts producing neurotrophin-3 (nt-3), brain-derived neurotrophic factor (bdnf), ciliary neurotrophic factor, nerve growth factor, basic fibroblast growth factor, or beta-galactosidase (control grafts) were transplanted subacutely into the contused adult rat spinal cord. |
1998-07-27 |
2023-08-12 |
rat |
| L Novikova, L Novikov, J O Kellert. Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517482. |
we compared the effects of peripheral nerve grafts, embryonic spinal cord transplants and brain-derived neurotrophic factor (bdnf) on the survival and axon regeneration of adult rat spinal motor neurons undergoing retrograde degeneration after ventral root avulsion. |
1998-04-24 |
2023-08-12 |
rat |
| L Novikova, L Novikov, J O Kellert. Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517482. |
however, intrathecal infusion of bdnf promoted long-term survival of the lesioned motor neurons and induced abundant motor axon regeneration from the avulsion zone along the spinal cord surface towards the bdnf source. |
1998-04-24 |
2023-08-12 |
rat |
| H A Vische. BDNF is expressed at the crush site after spinal cord lesion in newborn opossum (Monodelphis domestica). The European journal of neuroscience. vol 9. issue 9. 1997-12-23. PMID:9383223. |
bdnf is expressed at the crush site after spinal cord lesion in newborn opossum (monodelphis domestica). |
1997-12-23 |
2023-08-12 |
chicken |