| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xueru Xu, Shaoxiong Fu, Xiaomei Shi, Rongguo Li. Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats. Pain research & management. vol 2019. 2019-12-16. PMID:31182984. |
the activated microglia, brain-derived neurotrophic factor (bdnf), phosphatidylinositol 3-kinase (pi3k), and phosphorylated extracellular signal-regulated kinase (p-erk) in the spinal cord were demonstrated to be involved in developing neuropathic pain. |
2019-12-16 |
2023-08-13 |
rat |
| Xueru Xu, Shaoxiong Fu, Xiaomei Shi, Rongguo Li. Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats. Pain research & management. vol 2019. 2019-12-16. PMID:31182984. |
here, we aim to investigate whether prf treatment could regulate the levels of bdnf, pi3k, and p-erk in the spinal cord of rats with spared nerve injury (sni) via suppressing the spinal microglia activation to ease neuropathic pain. |
2019-12-16 |
2023-08-13 |
rat |
| Patrik Ernfors, Håkan Persso. Developmentally Regulated Expression of HDNF/NT-3 mRNA in Rat Spinal Cord Motoneurons and Expression of BDNF mRNA in Embryonic Dorsal Root Ganglion. The European journal of neuroscience. vol 3. issue 10. 2019-11-20. PMID:12106253. |
developmentally regulated expression of hdnf/nt-3 mrna in rat spinal cord motoneurons and expression of bdnf mrna in embryonic dorsal root ganglion. |
2019-11-20 |
2023-08-12 |
rat |
| Seung Hoon Lee, Yongsun Kim, Daeun Rhew, Ahyoung Kim, Kwang Rae Jo, Yongseok Yoon, Kyeung Uk Choi, Taeseong Jung, Wan Hee Kim, Oh-Kyeong Kweo. Impact of local injection of brain-derived neurotrophic factor-expressing mesenchymal stromal cells (MSCs) combined with intravenous MSC delivery in a canine model of chronic spinal cord injury. Cytotherapy. 2019-11-20. PMID:28029610. |
we investigated whether combined transplantation of chondroitinase abc (chabc) and mesenchymal stromal cells (mscs) genetically modified to secrete brain-derived neurotrophic factor (bdnf) with intravenous (iv) administration of mscs can promote recovery of hindlimb function after chronic spinal cord injury (sci). |
2019-11-20 |
2023-08-13 |
Not clear |
| Madeline Nicholson, Rhiannon J Wood, Jessica L Fletcher, Maarten van den Buuse, Simon S Murray, Junhua Xia. BDNF haploinsufficiency exerts a transient and regionally different influence upon oligodendroglial lineage cells during postnatal development. Molecular and cellular neurosciences. vol 90. 2019-11-20. PMID:29782918. |
our data identify that bdnf heterozygosity results in transient reductions in oligodendroglial lineage cell density and progression that are largely restricted to the optic nerve, whereas the corpus callosum, cerebral cortex, basal forebrain and spinal cord white matter tracts are unaffected. |
2019-11-20 |
2023-08-13 |
mouse |
| Madeline Nicholson, Rhiannon J Wood, Jessica L Fletcher, Maarten van den Buuse, Simon S Murray, Junhua Xia. BDNF haploinsufficiency exerts a transient and regionally different influence upon oligodendroglial lineage cells during postnatal development. Molecular and cellular neurosciences. vol 90. 2019-11-20. PMID:29782918. |
in the first two postnatal weeks, bdnf het mice exhibit reductions in the density of oligodendroglial lineage cells, oligodendrocyte precursor cells (opcs) and postmitotic oligodendrocytes selectively in the optic nerve, but not in the brain or spinal cord white matter tracts. |
2019-11-20 |
2023-08-13 |
mouse |
| Qinfeng Wu, Qinghua Wang, Zhangjie Li, Xiangzhe Li, Jing Zang, Zhangwei Wang, Chen Xu, Yujia Gong, Jiaqi Cheng, Haoming Li, Guangyu Shen, Chuanming Don. Human menstrual blood-derived stem cells promote functional recovery in a rat spinal cord hemisection model. Cell death & disease. vol 9. issue 9. 2019-11-20. PMID:30158539. |
additionally, immunofluorescence, western blot, and qrt-pcr methods showed that levels of brain-derived neurotrophic factor (bdnf) were significantly higher in the injured spinal cord after implantation of menscs. |
2019-11-20 |
2023-08-13 |
human |
| Qinfeng Wu, Qinghua Wang, Zhangjie Li, Xiangzhe Li, Jing Zang, Zhangwei Wang, Chen Xu, Yujia Gong, Jiaqi Cheng, Haoming Li, Guangyu Shen, Chuanming Don. Human menstrual blood-derived stem cells promote functional recovery in a rat spinal cord hemisection model. Cell death & disease. vol 9. issue 9. 2019-11-20. PMID:30158539. |
it was eventually revealed that menscs implantation had beneficial therapeutic effects on the rehabilitation of the rat spinal cord hemisection model, mainly by enhancing the expression of bdnf. |
2019-11-20 |
2023-08-13 |
human |
| Biswarup Ghosh, Zhicheng Wang, Jia Nong, Mark W Urban, Zhiling Zhang, Victoria A Trovillion, Megan C Wright, Yinghui Zhong, Angelo C Lepor. Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29891731. |
local bdnf delivery to the injured cervical spinal cord using an engineered hydrogel enhances diaphragmatic respiratory function. |
2019-10-28 |
2023-08-13 |
rat |
| Biswarup Ghosh, Zhicheng Wang, Jia Nong, Mark W Urban, Zhiling Zhang, Victoria A Trovillion, Megan C Wright, Yinghui Zhong, Angelo C Lepor. Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29891731. |
we developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (bdnf) to injured cervical spinal cord. |
2019-10-28 |
2023-08-13 |
rat |
| Biswarup Ghosh, Zhicheng Wang, Jia Nong, Mark W Urban, Zhiling Zhang, Victoria A Trovillion, Megan C Wright, Yinghui Zhong, Angelo C Lepor. Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29891731. |
implantation of bdnf hydrogel after c4/c5 contusion-type spinal cord injury (sci) in female rats robustly preserved diaphragm function, as assessed by |
2019-10-28 |
2023-08-13 |
rat |
| Paul A Smith, Cindy Schmid, Stefan Zurbruegg, Magali Jivkov, Arno Doelemeyer, Diethilde Theil, Valérie Dubost, Nicolau Beckman. Fingolimod inhibits brain atrophy and promotes brain-derived neurotrophic factor in an animal model of multiple sclerosis. Journal of neuroimmunology. vol 318. 2019-09-30. PMID:29530550. |
brain volume changes were quantified using magnetic resonance imaging (mri) at 7 tesla and correlated to treatment-induced brain derived neurotrophic factor (bdnf) measured in blood, cerebrospinal fluid, spinal cord and brain. |
2019-09-30 |
2023-08-13 |
mouse |
| James W Grau, Yung-Jen Huan. Metaplasticity within the spinal cord: Evidence brain-derived neurotrophic factor (BDNF), tumor necrosis factor (TNF), and alterations in GABA function (ionic plasticity) modulate pain and the capacity to learn. Neurobiology of learning and memory. vol 154. 2019-09-23. PMID:29635030. |
metaplasticity within the spinal cord: evidence brain-derived neurotrophic factor (bdnf), tumor necrosis factor (tnf), and alterations in gaba function (ionic plasticity) modulate pain and the capacity to learn. |
2019-09-23 |
2023-08-13 |
Not clear |
| Imdad Ullah Khan, Yongseok Yoon, Ahyoung Kim, Kwang Rae Jo, Kyeung Uk Choi, Taeseong Jung, Namyul Kim, YeonSung Son, Wan Hee Kim, Oh-Kyeong Kweo. Improved Healing after the Co-Transplantation of HO-1 and BDNF Overexpressed Mesenchymal Stem Cells in the Subacute Spinal Cord Injury of Dogs. Cell transplantation. vol 27. issue 7. 2019-09-23. PMID:29909686. |
improved healing after the co-transplantation of ho-1 and bdnf overexpressed mesenchymal stem cells in the subacute spinal cord injury of dogs. |
2019-09-23 |
2023-08-13 |
Not clear |
| Olga Kononenko, Hiroyuki Watanabe, Lada Stålhandske, Ann Zarelius, Fredrik Clausen, Tatiana Yakovleva, Georgy Bakalkin, Niklas Marklun. Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord. Restorative neurology and neuroscience. vol 37. issue 2. 2019-07-08. PMID:30856132. |
absolute expression levels of tgfb1, c-fos, bdnf, and gapd43 genes were measured by droplet digital pcr in ipsi-and contralesional, dorsal and ventral quadrants of the l4 and l5 spinal cord. |
2019-07-08 |
2023-08-13 |
rat |
| Zahra Hassannejad, Shayan Abdollah Zadegan, Alexander R Vaccaro, Vafa Rahimi-Movaghar, Omid Sabzevar. Corrigendum to "Biofunctionalized peptide-based hydrogel as an injectable scaffold for BDNF delivery can improve regeneration after spinal cord Injury" [Injury Int. J. Care Injured 50 (2019) 278-285]. Injury. vol 50. issue 6. 2019-07-02. PMID:31027829. |
corrigendum to "biofunctionalized peptide-based hydrogel as an injectable scaffold for bdnf delivery can improve regeneration after spinal cord injury" [injury int. |
2019-07-02 |
2023-08-13 |
Not clear |
| Zahra Hassannejad, Shayan Abdollah Zadegan, Alexander R Vaccaro, Vafa Rahimi-Movaghar, Omid Sabzevar. Biofunctionalized peptide-based hydrogel as an injectable scaffold for BDNF delivery can improve regeneration after spinal cord injury. Injury. vol 50. issue 2. 2019-06-25. PMID:30595411. |
biofunctionalized peptide-based hydrogel as an injectable scaffold for bdnf delivery can improve regeneration after spinal cord injury. |
2019-06-25 |
2023-08-13 |
Not clear |
| Su Pan, Zhiping Qi, Qiuju Li, Yue Ma, Chuan Fu, Shuang Zheng, Weijian Kong, Qinyi Liu, Xiaoyu Yan. Graphene oxide-PLGA hybrid nanofibres for the local delivery of IGF-1 and BDNF in spinal cord repair. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-06-17. PMID:30829545. |
graphene oxide-plga hybrid nanofibres for the local delivery of igf-1 and bdnf in spinal cord repair. |
2019-06-17 |
2023-08-13 |
Not clear |
| Sean M Gannon, Kiel Hawk, Brian F Walsh, Aminata Coulibaly, Lori G Isaacso. Retrograde influences of SCG axotomy on uninjured preganglionic neurons. Brain research. vol 1691. 2019-05-06. PMID:29679543. |
in order to understand the mechanisms underlying these changes, protein levels of brain-derived neurotrophic factor (bdnf) and tyrosine receptor kinase b (trkb) were examined and reductions were observed at 7 days post-injury in both the scg and spinal cord. |
2019-05-06 |
2023-08-13 |
Not clear |
| Sean M Gannon, Kiel Hawk, Brian F Walsh, Aminata Coulibaly, Lori G Isaacso. Retrograde influences of SCG axotomy on uninjured preganglionic neurons. Brain research. vol 1691. 2019-05-06. PMID:29679543. |
taken together these results suggest that axotomy of the scg led to reduced bdnf in the scg and spinal cord, which in turn influenced chat and synaptophysin expression in the scg and also contributed to the altered synaptic input to the iml neurons. |
2019-05-06 |
2023-08-13 |
Not clear |