| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michiharu Matsuda, Haruo Kanno, Takehiro Sugaya, Seiji Yamaya, Kenichiro Yahata, Kyoichi Handa, Tomohiko Shindo, Hiroaki Shimokawa, Hiroshi Ozawa, Eiji Ito. Low-energy extracorporeal shock wave therapy promotes BDNF expression and improves functional recovery after spinal cord injury in rats. Experimental neurology. vol 328. 2020-12-30. PMID:32087252. |
these findings indicate that low-energy eswt promotes bdnf expression at the lesion site and reduces the neural tissue damage and functional impairment following spinal cord injury. |
2020-12-30 |
2023-08-13 |
human |
| Rômulo Nolasco de Brito, Daniela D Ludtke, Bruna Hoffmann de Oliveira, Taynah de Oliveira Galassi, Paula Franson Fernandes, Sarah Van Den Berge, Afonso Shiguemi Inoue Salgado, Francisco José Cidral-Filho, Verônica Vargas Horewicz, Franciane Bobinski, Daniel Fernandes Martin. Balneotherapy decreases mechanical hyperalgesia by reversing BDNF and NOS2 immunocontent in spinal cord of mice with neuropathic pain. Journal of neuroimmunology. vol 348. 2020-12-14. PMID:32862113. |
balneotherapy decreases mechanical hyperalgesia by reversing bdnf and nos2 immunocontent in spinal cord of mice with neuropathic pain. |
2020-12-14 |
2023-08-13 |
mouse |
| Rômulo Nolasco de Brito, Daniela D Ludtke, Bruna Hoffmann de Oliveira, Taynah de Oliveira Galassi, Paula Franson Fernandes, Sarah Van Den Berge, Afonso Shiguemi Inoue Salgado, Francisco José Cidral-Filho, Verônica Vargas Horewicz, Franciane Bobinski, Daniel Fernandes Martin. Balneotherapy decreases mechanical hyperalgesia by reversing BDNF and NOS2 immunocontent in spinal cord of mice with neuropathic pain. Journal of neuroimmunology. vol 348. 2020-12-14. PMID:32862113. |
we found that balneotherapy reduced mechanical hyperalgesia, as well the increase of bdnf and nos2 levels in the spinal cord, while increased bdnf and nos1 in the paw. |
2020-12-14 |
2023-08-13 |
mouse |
| Naoki Wada, Naoki Yoshimura, Masahiro Kurobe, Tetsuichi Saito, Pradeep Tyagi, Hidehiro Kakizak. The early, long-term inhibition of brain-derived neurotrophic factor improves voiding, and storage dysfunctions in mice with spinal cord injury. Neurourology and urodynamics. vol 39. issue 5. 2020-12-11. PMID:32394603. |
we examined the time course of urodynamic changes and the effect of the short or long-term inhibition of brain-derived neurotrophic factor (bdnf) from the early phase after spinal cord injury (sci) in mice. |
2020-12-11 |
2023-08-13 |
mouse |
| Maria Serena Paladini, Davide Marangon, Andrea C Rossetti, Alice Guidi, Giusy T Coppolino, Camilla Negri, Vittoria Spero, Maria Pia Abbracchio, Davide Lecca, Raffaella Molten. Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. Cellular and molecular neurobiology. 2020-12-01. PMID:33259004. |
prenatal stress impairs spinal cord oligodendrocyte maturation via bdnf signaling in the experimental autoimmune encephalomyelitis model of multiple sclerosis. |
2020-12-01 |
2023-08-13 |
mouse |
| Che Aishah Nazariah Ismail, Rapeah Suppian, Che Badariah Ab Aziz, Idris Lon. Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats. Neuropeptides. vol 79. 2020-11-23. PMID:31902597. |
this study aimed to investigate microglia activation and signalling molecules brain-derived neurotrophic factor (bdnf) and downstream regulatory element antagonist modulator (dream) proteins in spinal cord of streptozotocin-induced diabetic neuropathy rats. |
2020-11-23 |
2023-08-13 |
rat |
| Xi Fang, Chun Yang, Shan Li, Gaofeng Zhan, Jie Zhang, Niannian Huang, Xiangxi Du, Hui Xu, Kenji Hashimoto, Ailin Lu. Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury. European archives of psychiatry and clinical neuroscience. vol 270. issue 2. 2020-11-06. PMID:29882089. |
furthermore, tissue levels of bdnf in the hippocampus, l2-5 spinal cord, muscle, and liver from both rats with or without anhedonia-like phenotype were lower compared with those of sham-operated rats. |
2020-11-06 |
2023-08-13 |
rat |
| Chunchun Xue, Lei Xie, Xia Li, Jianfeng Cai, Zhen Gu, Kaiqiang Wan. Analgesic mechanism of electroacupuncture in a rat L5 spinal nerve ligation model. Experimental and therapeutic medicine. vol 9. issue 3. 2020-10-01. PMID:25667665. |
the mrna levels of brain-derived neurotrophic factor (bdnf) and purinergic receptor p2x, ligand-gated ion channel 4 (p2x4) in the spinal cord (n=14) were determined by reverse transcription-quantitative polymerase chain reaction (rt-qpcr). |
2020-10-01 |
2023-08-13 |
rat |
| You-Mi Kim, Jun-Jang Jin, Sam-Jun Lee, Tae-Beom Seo, Eun-Sang J. Treadmill exercise with bone marrow stromal cells transplantation facilitates neuroprotective effect through BDNF-ERK1/2 pathway in spinal cord injury rats. Journal of exercise rehabilitation. vol 14. issue 3. 2020-10-01. PMID:30018915. |
in the present results, combination of bmscs transplantation with tread-mill exercise potently decreased bax expression, potently increased bcl-2 expression, and potently enhanced bdnf and trkb expressions in the injured spinal cord. |
2020-10-01 |
2023-08-13 |
rat |
| Jeffri Retamal, Andrea Reyes, Paulina Ramirez, David Bravo, Alejandro Hernandez, Teresa Pelissier, Luis Villanueva, Luis Constandi. Burst-Like Subcutaneous Electrical Stimulation Induces BDNF-Mediated, Cyclotraxin B-Sensitive Central Sensitization in Rat Spinal Cord. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30364099. |
intrathecal administration of brain derived neurotrophic factor (bdnf) induces long-term potentiation (ltp) and generates long-lasting central sensitization in spinal cord thus mimicking chronic pain, but the relevance of these observations to chronic pain mechanisms is uncertain. |
2020-10-01 |
2023-08-13 |
rat |
| Jeffri Retamal, Andrea Reyes, Paulina Ramirez, David Bravo, Alejandro Hernandez, Teresa Pelissier, Luis Villanueva, Luis Constandi. Burst-Like Subcutaneous Electrical Stimulation Induces BDNF-Mediated, Cyclotraxin B-Sensitive Central Sensitization in Rat Spinal Cord. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30364099. |
since c-fiber activation by a high-frequency subcutaneous electrical stimulation (ses) protocol causes spinal release of bdnf and induces spinal cord ltp, we propose that application of such protocol would be a sufficient condition for generating long-lasting bdnf-mediated central sensitization. |
2020-10-01 |
2023-08-13 |
rat |
| Liliana Brambilla, Francesca Martorana, Giulia Guidotti, Daniela Ross. Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30210286. |
here, we show that the interaction of hmgb1 with normal spinal cord astrocytes induces the astrocytic production of neurotrophic factors, particularly brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf). |
2020-09-30 |
2023-08-13 |
Not clear |
| Parichat On-Ong-Arj, Jintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukham-Me. Yellow Laser Stimulation at GV2 Acupoint Mitigates Apoptosis, Oxidative Stress, Inflammation, and Motor Deficit in Spinal Cord Injury Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-09-30. PMID:30402127. |
at the end of study period, the densities of polymorphonuclear of leukocyte, bax, caspase-3, bcl-2, and bdnf positive stained cells in ventral horn of spinal cord were determined. |
2020-09-30 |
2023-08-13 |
rat |
| Parichat On-Ong-Arj, Jintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukham-Me. Yellow Laser Stimulation at GV2 Acupoint Mitigates Apoptosis, Oxidative Stress, Inflammation, and Motor Deficit in Spinal Cord Injury Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-09-30. PMID:30402127. |
the results showed that laser acupuncture at gv2 increased bbb score, gross motor score, and densities of bcl-2 and bdnf positive stained cells but decreased density with polymorphonuclear leukocyte, the densities of bax and caspase-3 positive stained cells, cox-2 level, and oxidative stress status in ventral horn of the lesion spinal cord. |
2020-09-30 |
2023-08-13 |
rat |
| Parichat On-Ong-Arj, Jintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukham-Me. Yellow Laser Stimulation at GV2 Acupoint Mitigates Apoptosis, Oxidative Stress, Inflammation, and Motor Deficit in Spinal Cord Injury Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2018. 2020-09-30. PMID:30402127. |
therefore, gv2 stimulation by yellow laser might enhance the recovery of spinal cord via the increase in bdnf and the decrease in inflammation, apoptosis, and oxidative stress status in the lesion spinal cord. |
2020-09-30 |
2023-08-13 |
rat |
| Che Aishah Nazariah Ismail, Rapeah Suppian, Che Badariah Abd Aziz, Idris Lon. Minocycline attenuates the development of diabetic neuropathy by modulating DREAM and BDNF protein expression in rat spinal cord. Journal of diabetes and metabolic disorders. vol 18. issue 1. 2020-09-30. PMID:31275889. |
minocycline attenuates the development of diabetic neuropathy by modulating dream and bdnf protein expression in rat spinal cord. |
2020-09-30 |
2023-08-13 |
rat |
| Sumit Mehrotra, Daniel Lynam, Ryan Maloney, Kendell M Pawelec, Mark H Tuszynski, Ilsoon Lee, Christina Chan, Jeffrey Sakamot. Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels. Advanced functional materials. vol 20. issue 2. 2020-09-29. PMID:20200599. |
support of linear axonal growth into spinal cord lesion sites has been demonstrated using arrays of uniaxial channels, templated with agarose hydrogel, and containing genetically engineered cells that secrete brain-derived neurotrophic factor (bdnf). |
2020-09-29 |
2023-08-12 |
Not clear |
| Jiedong Liang, Gui Deng, He Huan. The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783437. |
the activation of bdnf reduced inflammation in a spinal cord injury model by trkb/p38 mapk signaling. |
2020-09-29 |
2023-08-13 |
rat |
| Jiedong Liang, Gui Deng, He Huan. The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783437. |
the aim of the present study was to investigate the pro-inflammation effects of brain-derived neurotrophic factor (bdnf) signaling in promoting inflammation following spinal cord injury (sci) in rats. |
2020-09-29 |
2023-08-13 |
rat |
| Jiedong Liang, Gui Deng, He Huan. The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783437. |
the basso, beattie and bresnahan (bbb) test was used and the water content of spinal cord were assessed to determine the effects of bdnf on sci. |
2020-09-29 |
2023-08-13 |
rat |