| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Shiver, M Familari, G Aguiler. Regulation of intermediate pituitary corticotropin-releasing hormone receptors by dopamine. Endocrinology. vol 130. issue 4. 1992-04-22. PMID:1347742. |
this study demonstrates that in contrast to the recognized inhibitory effect on cell division and pomc mrna expression, dopamine causes up-regulation of crh receptors in the intermediate pituitary. |
1992-04-22 |
2023-08-11 |
rat |
| S L'Héreault, N Barde. Monoaminergic regulation of proopiomelanocortin messenger RNA concentrations in primary cell cultures of rat hypothalamus. Brain research. Molecular brain research. vol 9. issue 4. 1991-06-28. PMID:1710012. |
dopamine markedly decreased pomc mrna levels in a dose related manner. |
1991-06-28 |
2023-08-11 |
rat |
| S L'Héreault, N Barde. Monoaminergic regulation of proopiomelanocortin messenger RNA concentrations in primary cell cultures of rat hypothalamus. Brain research. Molecular brain research. vol 9. issue 4. 1991-06-28. PMID:1710012. |
the selective dopamine d1 receptor agonist, skf 38393, as well as norepinephrine and acetylcholine did not affect pomc mrna levels. |
1991-06-28 |
2023-08-11 |
rat |
| S L'Héreault, N Barde. Monoaminergic regulation of proopiomelanocortin messenger RNA concentrations in primary cell cultures of rat hypothalamus. Brain research. Molecular brain research. vol 9. issue 4. 1991-06-28. PMID:1710012. |
it is concluded that serotonin exerts a positive control and dopamine a negative control on pomc mrna concentrations in primary cultures of rat hypothalamic neurons. |
1991-06-28 |
2023-08-11 |
rat |
| N Liao, M Bulant, P Nicolas, H Vaudry, G Pelletie. Anatomical interactions of proopiomelanocortin (POMC)-related peptides, neuropeptide Y (NPY) and dopamine beta-hydroxylase (D beta H) fibers and thyrotropin-releasing hormone (TRH) neurons in the paraventricular nucleus of rat hypothalamus. Neuropeptides. vol 18. issue 2. 1991-05-22. PMID:1901963. |
anatomical interactions of proopiomelanocortin (pomc)-related peptides, neuropeptide y (npy) and dopamine beta-hydroxylase (d beta h) fibers and thyrotropin-releasing hormone (trh) neurons in the paraventricular nucleus of rat hypothalamus. |
1991-05-22 |
2023-08-11 |
rat |
| G D Hammer, V Fairchild-Huntress, M J Lo. Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice. Molecular endocrinology (Baltimore, Md.). vol 4. issue 11. 1991-03-11. PMID:2177840. |
pomc gene transcription in corticotrophs is induced by hypothalamic crh and vasopressin and inhibited by adrenal glucocorticoids, while in melanotrophs it is predominantly regulated by beta-adrenergic neural input and dopamine. |
1991-03-11 |
2023-08-11 |
mouse |
| C Hindelang, J M Félix, F M Laurent, M J Klein, M E Stoecke. Ontogenesis of proopiomelanocortin gene expression and regulation in the rat pituitary intermediate lobe. Molecular and cellular endocrinology. vol 70. issue 3. 1990-08-08. PMID:2361568. |
the effects of acute or chronic postnatal treatment with a dopamine antagonist (haloperidol) or a dopamine agonist (bromocriptine) show that the physiological dopaminergic inhibitory control of pomc gene expression operates as early as postnatal day 5. |
1990-08-08 |
2023-08-11 |
rat |
| K Pardy, D Carter, D Murph. Dopaminergic mediation of physiological changes in proopiomelanocortin messenger ribonucleic acid expression in the neurointermediate lobe of the rat pituitary. Endocrinology. vol 126. issue 6. 1990-07-13. PMID:2161741. |
the dopamine d2 receptor antagonist domperidone blocked the inhibitory effect of salt load on pomc mrna in the neurointermediate lobe, while the d2 agonist bromocriptine mimicked the effect of salt load. |
1990-07-13 |
2023-08-11 |
rat |
| D J Autelitano, L Snyder, S C Sealfon, J L Robert. Dopamine D2-receptor messenger RNA is differentially regulated by dopaminergic agents in rat anterior and neurointermediate pituitary. Molecular and cellular endocrinology. vol 67. issue 1. 1990-03-01. PMID:2575547. |
hypothalamic dopamine (da), acting at da d2-receptors (d2-r) on pituitary target cells, mediates peptide release and biosynthesis of rat pituitary anterior lobe (al) prolactin, and neurointermediate lobe (nil) pro-opiomelanocortin (pomc). |
1990-03-01 |
2023-08-11 |
rat |
| R A Felder, D S Garlan. POMC biosynthesis in the intermediate lobe of the spontaneously hypertensive rat. American journal of hypertension. vol 2. issue 8. 1989-10-19. PMID:2550032. |
the decreased pomc biosynthesis was associated with a higher dopamine content in il in shr compared to wky (1.56 +/- 0.53, n = 17 v 0.51 +/- 0.16, n = 17 pmol/il, p less than 0.05, mann-whitney test). |
1989-10-19 |
2023-08-11 |
rat |
| R J Kemppainen, J L Sarti. Differential secretion of pro-opiomelanocortin peptides by the pars distalis and pars intermedia of beagle dogs. The Journal of endocrinology. vol 117. issue 1. 1988-05-26. PMID:2833553. |
beagle dogs were given saline, insulin or the dopamine antagonist, haloperidol, to examine peripheral concentrations of immunoreactive (ir)-pro-opiomelanocortin (pomc) peptides resulting from pars distalis or pars intermedia stimulation. |
1988-05-26 |
2023-08-11 |
Not clear |
| J P Loeffler, B A Demeneix, N A Kley, V Höll. Dopamine inhibition of proopiomelanocortin gene expression in the intermediate lobe of the pituitary. Interactions with corticotropin-releasing factor and the beta-adrenergic receptors and the adenylate cyclase system. Neuroendocrinology. vol 47. issue 2. 1988-04-05. PMID:2963967. |
the effects of dopamine on proopiomelanocortin (pomc) gene expression were compared in primary cultures of the anterior and intermediate lobes of the rat pituitary. |
1988-04-05 |
2023-08-11 |
rat |
| J P Loeffler, B A Demeneix, N A Kley, V Höll. Dopamine inhibition of proopiomelanocortin gene expression in the intermediate lobe of the pituitary. Interactions with corticotropin-releasing factor and the beta-adrenergic receptors and the adenylate cyclase system. Neuroendocrinology. vol 47. issue 2. 1988-04-05. PMID:2963967. |
treatment with dopamine (1 microm) for 48 h reduced pomc messenger rna levels in the intermediate lobe by 77%, but had no effect on pomc gene expression in the anterior lobe. |
1988-04-05 |
2023-08-11 |
rat |
| J P Loeffler, B A Demeneix, N A Kley, V Höll. Dopamine inhibition of proopiomelanocortin gene expression in the intermediate lobe of the pituitary. Interactions with corticotropin-releasing factor and the beta-adrenergic receptors and the adenylate cyclase system. Neuroendocrinology. vol 47. issue 2. 1988-04-05. PMID:2963967. |
the decrease in pomc messenger rna levels was dose dependent with ed50 values of about 50 and 0.1 nm for dopamine and bromocriptine, respectively. |
1988-04-05 |
2023-08-11 |
rat |
| J P Loeffler, N Kley, C W Pittius, V Höll. Regulation of proopiomelanocortin (POMC) mRNA levels in primary pituitary cultures. NIDA research monograph. vol 75. 1988-03-18. PMID:3123958. |
in contrast, dopamine (10(-6) m) and gaba (10(-6) m) decreased pomc mrna levels in the il cells to about 50% of control levels without affecting pomc mrna levels in the al cells. |
1988-03-18 |
2023-08-11 |
mouse |
| D J Autelitano, J A Clements, I Nikolaidis, B J Canny, J W Funde. Concomitant dopaminergic and glucocorticoid control of pituitary proopiomelanocortin messenger ribonucleic acid and beta-endorphin levels. Endocrinology. vol 121. issue 5. 1987-12-07. PMID:2959468. |
in the nil, the dopamine agonist bromocriptine reduced and the antagonist haloperidol raised both pomc mrna and ir-beta ep content. |
1987-12-07 |
2023-08-11 |
rat |
| B M Chronwall, W R Millington, W S Griffin, J R Unnerstall, T L O'Donohu. Histological evaluation of the dopaminergic regulation of proopiomelanocortin gene expression in the intermediate lobe of the rat pituitary, involving in situ hybridization and [3H]thymidine uptake measurement. Endocrinology. vol 120. issue 3. 1987-03-26. PMID:3803315. |
these results suggest that dopamine regulation of the il acts by two different mechanisms: pomc gene expression and cellular proliferation. |
1987-03-26 |
2023-08-11 |
rat |
| A J Dunn, E L Webster, C B Nemerof. Neonatal treatment with monosodium glutamate does not alter grooming behavior induced by novelty or adrenocorticotropic hormone. Behavioral and neural biology. vol 44. issue 1. 1986-05-27. PMID:3010931. |
administration of monosodium glutamate (msg) to neonatal rats destroys neurons in the arcuate nucleus of the hypothalamus, depleting the brain of pomc peptides, and also hypothalamic dopamine and choline acetyl-transferase activity. |
1986-05-27 |
2023-08-11 |
rat |
| O Bosler, A Beaude. [Ultrastructural relations between monoaminergic and peptidergic systems in the hypothalamus. Radioautographic approach and immunocytochemical binding in the arcuate nucleus and suprachiasmatic nucleus in the rat]. Annales d'endocrinologie. vol 46. issue 1. 1986-02-10. PMID:4083812. |
this paper deals with the cytological substratum for interactions between serotonin and dopamine, pro-opiomelanocortin (pomc) or vasoactive intestinal peptide (vip) within the hypothalamus. |
1986-02-10 |
2023-08-11 |
rat |
| S L Wardlaw, P J Wang, A G Frant. Regulation of beta-endorphin and ACTH in brain by estradiol. Life sciences. vol 37. issue 20. 1985-12-18. PMID:2997573. |
dopamine, a known inhibitor of pituitary intermediate lobe pro-opiomelanocortin (pomc), was examined as a possible mediator of the estradiol induced changes in brain pomc. |
1985-12-18 |
2023-08-11 |
rat |