| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ebstein, C Roberge, J Tabachnick, M Goldstei. The effect of dopamine and of apomorphine on dB-cAMP induced stimulation of synaptosomal tyrosine hydroxylase. The Journal of pharmacy and pharmacology. vol 26. issue 12. 1975-09-22. PMID:4156865. |
the effect of dopamine and of apomorphine on db-camp induced stimulation of synaptosomal tyrosine hydroxylase. |
1975-09-22 |
2023-08-11 |
Not clear |
| N J Uretsky, G J Chase, A V Lorenz. Effect of alpha-methyldopa on dopamine synthesis and release in rat striatum in vitro. The Journal of pharmacology and experimental therapeutics. vol 193. issue 1. 1975-08-22. PMID:237116. |
these results, as well as the close similarity between the percent reduction of 3-h-h2o formation and tissue 3-h-da levels, suggest that alpha-methyldopa decreases tissue levels of dopamine by inhibiting tyrosine hydroxylase activity in da neurons. |
1975-08-22 |
2023-08-11 |
rat |
| J E Harris, R J Baldessarini, V H Morgenroth, R H Rot. Activation by cyclic 3':5'-adenosine monophosphate of tyrosine hydroxylase in the rat brain. Proceedings of the National Academy of Sciences of the United States of America. vol 72. issue 3. 1975-07-14. PMID:236558. |
increased activity of soluble tyrosine hydroxylase was reflected in increased affinity (km) for substrate and cofactor and decreased affinity (ki) for inhibitory end-product (dopamine), suggesting a change in the physical-chemical state of the enzyme or an activator molecule. |
1975-07-14 |
2023-08-11 |
rat |
| Y Ben-Ari, R E Zigmond, K E Moor. Regional distribution of tyrosine hydroxylase, norepinephrine and dopamine within the amygdaloid complex of the rat. Brain research. vol 87. issue 1. 1975-06-25. PMID:235349. |
regional distribution of tyrosine hydroxylase, norepinephrine and dopamine within the amygdaloid complex of the rat. |
1975-06-25 |
2023-08-11 |
rat |
| D Quartermain, C Y Botwinic. Role of the biogenic amines in the reversal of cycloheximide-induced amnesia. Journal of comparative and physiological psychology. vol 88. issue 1. 1975-06-25. PMID:235572. |
depletion of catecholamines by alpha-methyl-para-tyrosine, a tyrosine hydroxylase inhibitor, and diethyldithiocarbamate, a dopamine beta hydroxylase inhbitor, resulted in an amnesia quantitatively and qualitatively similar to amnesia induced by cyc. |
1975-06-25 |
2023-08-11 |
Not clear |
| B Zivkovic, A Guidott. Changes of kinetic constant of striatal tyrosine hydroxylase elicited by neuroleptics that impair the function of dopamine receptors. Brain research. vol 79. issue 3. 1975-01-15. PMID:4153770. |
changes of kinetic constant of striatal tyrosine hydroxylase elicited by neuroleptics that impair the function of dopamine receptors. |
1975-01-15 |
2023-08-11 |
Not clear |
| I Marshall, C B Smit. Acute and chronic morphine treatment and the hydroxylation of (1-14C)-L-tyrosine in the mouse brain. British journal of pharmacology. vol 50. issue 3. 1974-11-08. PMID:4152762. |
there- fore, changes in tyrosine hydroxylase activity, measured in vitro, could account for the changes in dopamine synthesis, but not noradrenaline synthesis, produced by morphine in vivo. |
1974-11-08 |
2023-08-11 |
mouse |
| X O Breakefield, M W Nirenber. Selection for neuroblastoma cells that synthesize certain transmitters. Proceedings of the National Academy of Sciences of the United States of America. vol 71. issue 6. 1974-09-17. PMID:4152249. |
tyrosine hydroxylase is found predominantly in adrenergic neurons and related cells that synthesize dopamine, norepinephrine, and epinephrine, and tryptophan hydroxylase in cells synthesizing serotonin or melatonin. |
1974-09-17 |
2023-08-11 |
mouse |
| G R Breese, T D Traylo. Developmental characteristics of brain catecholamines and tyrosine hydroxylase in the rat: effects of 6-hydroxydopamine. British journal of pharmacology. vol 44. issue 2. 1974-02-27. PMID:4148915. |
brain noradrenaline, dopamine and tyrosine hydroxylase were found in rat brain a few days before birth and increased progressively until reaching adult values. |
1974-02-27 |
2023-08-11 |
rat |
| G R Breese, T D Traylo. Developmental characteristics of brain catecholamines and tyrosine hydroxylase in the rat: effects of 6-hydroxydopamine. British journal of pharmacology. vol 44. issue 2. 1974-02-27. PMID:4148915. |
the intracisternal administration of 6-hydroxydopamine to rats 7 days of age reduced concentrations of noradrenaline, dopamine, and tyrosine hydroxylase by 72 hours.3. |
1974-02-27 |
2023-08-11 |
rat |
| G R Breese, T D Traylo. Developmental characteristics of brain catecholamines and tyrosine hydroxylase in the rat: effects of 6-hydroxydopamine. British journal of pharmacology. vol 44. issue 2. 1974-02-27. PMID:4148915. |
the concentrations of noradrenaline, dopamine or tyrosine hydroxylase in rats that received 6-hydroxydopamine at 7 or 14 days of age remained markedly reduced when determined at adulthood, indicating that fibres did not continue to develop after the administration of this compound. |
1974-02-27 |
2023-08-11 |
rat |
| B Jarrott, L B Geffe. Rapid axoplasmic transport of tyrosine hydroxylase in relation to other cytoplasmic constituents. Proceedings of the National Academy of Sciences of the United States of America. vol 69. issue 11. 1973-01-29. PMID:4117772. |
the transport of norepinephrine and two key enzymes involved in its synthesis, tyrosine hydroxylase (ec 1.14.3a) and dopamine beta-hydroxylase (ec 1.14.2.1), has been studied in relation to other axonal constituents in ligated chicken sciatic nerves. |
1973-01-29 |
2023-08-11 |
chicken |
| B Jarrott, L B Geffe. Rapid axoplasmic transport of tyrosine hydroxylase in relation to other cytoplasmic constituents. Proceedings of the National Academy of Sciences of the United States of America. vol 69. issue 11. 1973-01-29. PMID:4117772. |
norepinephrine, tyrosine hydroxylase, and dopamine beta-hydroxylase activity all increased proximal to the constriction over a 20-hr period. |
1973-01-29 |
2023-08-11 |
chicken |
| B Jarrott, L B Geffe. Rapid axoplasmic transport of tyrosine hydroxylase in relation to other cytoplasmic constituents. Proceedings of the National Academy of Sciences of the United States of America. vol 69. issue 11. 1973-01-29. PMID:4117772. |
the rate of transport of norepinephrine, tyrosine hydroxylase, and dopamine beta-hydroxylase were calculated as 2.6, 1.9, and 3.4 mm/hr, respectively. |
1973-01-29 |
2023-08-11 |
chicken |
| H Thoenen, P U Angeletti, R Levi-Montalcini, R Kettle. Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proceedings of the National Academy of Sciences of the United States of America. vol 68. issue 7. 1971-09-23. PMID:5283951. |
these morphological changes were accompanied by selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase (ec 1.14.2.1), whereas the total and specific activities of other enzymes involved in biosynthesis or metabolic degradation of norepinephrine rose only in proportion to the increase in volume of the sympathetic ganglia. |
1971-09-23 |
2023-08-11 |
rat |
| G R Breese, T D Traylo. Depletion of brain noradrenaline and dopamine by 6-hydroxydopamine. British journal of pharmacology. vol 42. issue 1. 1971-07-27. PMID:5580702. |
administration of 6-hydroxydopamine to developing rats lowered both noradrenaline and dopamine concentrations as well as the tyrosine hydroxylase activity in the brains of these animals. |
1971-07-27 |
2023-08-11 |
rat |
| R L Patrick, N Kirshne. Effect of stimulation on the levels of tyrosine hydroxylase, dopamine beta-hydroxylase, and catecholamines in intact and denervated rat adrenal glands. Molecular pharmacology. vol 7. issue 1. 1971-06-01. PMID:5552254. |
effect of stimulation on the levels of tyrosine hydroxylase, dopamine beta-hydroxylase, and catecholamines in intact and denervated rat adrenal glands. |
1971-06-01 |
2023-08-11 |
rat |
| I Nagatsu, T Nagatsu, K Mizutani, H Umezawa, M Matsuzaki, T Takeuch. Adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats. Nature. vol 230. issue 5293. 1971-05-25. PMID:4927727. |
adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats. |
1971-05-25 |
2023-08-11 |
rat |
| G Jonsson, C Sach. Synthesis of noradrenaline from 3,4-dihydroxyphenylalanine (DOPA) and dopamine in adrenergic nerves of mouse atrium--effect of reserpine, monoamine oxidase and tyrosine hydroxylase inhibition. Acta physiologica Scandinavica. vol 80. issue 3. 1971-02-02. PMID:5486459. |
synthesis of noradrenaline from 3,4-dihydroxyphenylalanine (dopa) and dopamine in adrenergic nerves of mouse atrium--effect of reserpine, monoamine oxidase and tyrosine hydroxylase inhibition. |
1971-02-02 |
2023-08-11 |
mouse |