| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shubhangini Tiwari, Parul Gupta, Abhishek Singh, Swati Chaturvedi, M Wahajuddin, Amit Mishra, Sarika Sing. 4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation. Neurochemical research. 2022-08-03. PMID:35922743. |
first, we observed the significant protective effects of 4pba on pd specific neuromuscular coordination, level of tyrosine hydroxylase, α-synuclein level and neurotransmitter dopamine in both substantia nigra and striatal regions of the experimental rat model of pd. |
2022-08-03 |
2023-08-14 |
rat |
| Shima Kouhnavardi, Alev Ecevitoglu, Vladimir Dragačević, Fabrizio Sanna, Edgar Arias-Sandoval, Predrag Kalaba, Michael Kirchhofer, Jana Lubec, Marco Niello, Marion Holy, Martin Zehl, Matthias Pillwein, Judith Wackerlig, Rita Murau, Andrea Mohrmann, Kathryn R Beard, Harald H Sitte, Ernst Urban, Claudia Sagheddu, Marco Pistis, Roberto Plasenzotti, John D Salamone, Thierry Langer, Gert Lubec, Francisco J Monj. A Novel and Selective Dopamine Transporter Inhibitor, Biomolecules. vol 12. issue 7. 2022-07-27. PMID:35883437. |
a novel and selective dopamine transporter inhibitor, dopamine (da), the most abundant human brain catecholaminergic neurotransmitter, modulates key behavioral and neurological processes in young and senescent brains, including motricity, sleep, attention, emotion, learning and memory, and social and reward-seeking behaviors. |
2022-07-27 |
2023-08-14 |
human |
| Anna Grete Wessel. Influence of the Gut Microbiome on Feed Intake of Farm Animals. Microorganisms. vol 10. issue 7. 2022-07-27. PMID:35889024. |
based on current evidence, the major mediators appear to be short-chain fatty acids (scfa), peptide hormones such as peptide yy (pyy) and glucagon-like peptide-1 (glp-1), as well as the amino acid tryptophan with the associated neurotransmitter serotonin, dopamine and γ-aminobutyrate (gaba). |
2022-07-27 |
2023-08-14 |
Not clear |
| Ewelina Królicka, Katarzyna Kieć-Kononowicz, Dorota Łażewsk. Chalcones as Potential Ligands for the Treatment of Parkinson's Disease. Pharmaceuticals (Basel, Switzerland). vol 15. issue 7. 2022-07-27. PMID:35890146. |
it has been proved that in the etiology and course of pd, the essential roles are played by dopamine (da) (an important neurotransmitter), enzymes regulating its level (e.g., comt, mao), and oxidative stress leading to neuroinflammation. |
2022-07-27 |
2023-08-14 |
Not clear |
| Kamil Pradel, Gniewosz Drwięga, Lukasz Chrobok, Tomasz Błasia. Racing and Pacing in the Reward System: A Multi-Clock Circadian Control Over Dopaminergic Signalling. Frontiers in physiology. vol 13. 2022-07-11. PMID:35812323. |
while endogenous circadian rhythms are weak in the ventral tegmental area and substantia nigra pars compacta, daily changes in expression of core clock genes, ion channels, neurotransmitter receptors, dopamine-synthesising enzymes, and dopamine transporters, accompanied by changes in electrical activity, are readily observed in these nuclei. |
2022-07-11 |
2023-08-14 |
human |
| Gabriel S Rocha, Marco Aurelio M Freire, Karina M Paiva, Rodrigo F Oliveira, Bianca Norrara, Paulão Leonardo A G Morais, Lucidio C Oliveira, Rovena Clara G J Engelberth, Jeferson S Cavalcante, José Rodolfo L P Cavalcant. Effect of senescence on the tyrosine hydroxylase and S100B immunoreactivity in the nigrostriatal pathway of the rat. Journal of chemical neuroanatomy. 2022-07-09. PMID:35809809. |
dopamine is a key neurotransmitter for the proper functioning of the brain, directly involved in circuitries related with emotions, learning, motivation and reward. |
2022-07-09 |
2023-08-14 |
rat |
| Malihe Mohamadian, Hossein Mortazavi, Mina Makvand, Fatemeh Ahangari, Hasem Ahangar. The Dopamine Gene Receptors (DRD1-5) Expression Alteration in Psoriasis Patients. Recent advances in inflammation & allergy drug discovery. 2022-06-30. PMID:35770390. |
since the neurotransmitter dopamine has a close association with stress configuration, it can be a candidate for relieving psoriasis representation. |
2022-06-30 |
2023-08-14 |
Not clear |
| Yang Wang, Jie Song, Xuedong Wang, Qiuhui Qian, Huili Wan. Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis. The Science of the total environment. 2022-06-30. PMID:35772538. |
tcs-chronic exposure affected the development of zebrafish, induced feminization, obesity physical signs and abnormal organ index and caused neurobehavioral abnormalities by inhibiting both neurotransmitter acetylcholinesterase and dopamine activity, promoting brain neuron apoptosis and accelerating diencephalic lesions. |
2022-06-30 |
2023-08-14 |
zebrafish |
| Sarah M Claypool, Sana Behdin, Sarah V Applebey, Javier Orihuel, Zilu Ma, David J Reine. Lack of causal roles of cannabinoid and dopamine neurotransmitter systems in orbitofrontal and piriform cortex in fentanyl relapse in rats. eNeuro. 2022-06-29. PMID:35768212. |
lack of causal roles of cannabinoid and dopamine neurotransmitter systems in orbitofrontal and piriform cortex in fentanyl relapse in rats. |
2022-06-29 |
2023-08-14 |
rat |
| Algarín Cecilia, Peirano Patricio, Chen Donna, Hafiz Rakibul, Reyes Sussanne, Lozoff Betsy, Biswal Bhara. Cognitive control inhibition networks in adulthood are impaired by early iron deficiency in infancy. NeuroImage. Clinical. vol 35. 2022-06-26. PMID:35753235. |
dopamine is the prevalent neurotransmitter underlying cognitive inhibition. |
2022-06-26 |
2023-08-14 |
human |
| Anna Kolacheva, Leyla Alekperova, Ekaterina Pavlova, Alyona Bannikova, Michael V Ugrumo. Changes in Tyrosine Hydroxylase Activity and Dopamine Synthesis in the Nigrostriatal System of Mice in an Acute Model of Parkinson's Disease as a Manifestation of Neurodegeneration and Neuroplasticity. Brain sciences. vol 12. issue 6. 2022-06-24. PMID:35741664. |
the synthesis of dopamine, the neurotransmitter of the nigrostriatal system, depends on the rate-limiting enzyme, tyrosine hydroxylase (th). |
2022-06-24 |
2023-08-14 |
mouse |
| A-K Brecht, E Medawar, R Thieleking, J Sacher, F Beyer, A Villringer, A V Witt. Dietary and serum tyrosine, white matter microstructure and inter-individual variability in executive functions in overweight adults: Relation to sex/gender and age. Appetite. 2022-06-23. PMID:35738483. |
tyrosine (tyr), the precursor of the neurotransmitter dopamine, is known to modulate cognitive functions including executive attention. |
2022-06-23 |
2023-08-14 |
Not clear |
| Waisley Yang, Rohit Singla, Oshin Maheshwari, Christine J Fontaine, Joana Gil-Mohape. Alcohol Use Disorder: Neurobiology and Therapeutics. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625928. |
ethanol exerts its toxicity through changes to multiple neurotransmitter systems, including serotonin, dopamine, gamma-aminobutyric acid, glutamate, acetylcholine, and opioid systems. |
2022-05-28 |
2023-08-13 |
Not clear |
| Sofia Elizarova, Abed Alrahman Chouaib, Ali Shaib, Björn Hill, Florian Mann, Nils Brose, Sebastian Kruss, James A Danie. A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 22. 2022-05-25. PMID:35613050. |
significancethe neurotransmitter dopamine controls normal behavior and dopaminergic dysfunction is prevalent in multiple brain diseases. |
2022-05-25 |
2023-08-13 |
Not clear |
| Ning-Xin Ma, Brendan Puls, Gong Che. Transcriptomic analyses of NeuroD1-mediated astrocyte-to-neuron conversion. Developmental neurobiology. 2022-05-24. PMID:35606902. |
neurod family members (neurod1/2/6) and signaling pathways (wnt, mapk, camp) as well as neurotransmitter receptors (acetylcholine, somatostatin, dopamine) were also significantly upregulated. |
2022-05-24 |
2023-08-13 |
Not clear |
| Christina Besada, Stacia I Lewandowski, Ole V Mortense. MKP3 Overexpression and ERK1/2 Phosphorylation in Dopaminergic Neurons Regulate DAT Trafficking and Function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552965. |
dopamine is a neurotransmitter that plays a critical role in movement, motivation, and reward. |
2022-05-13 |
2023-08-13 |
rat |
| Smita Mathew, Joy P Keerikkatti. Lineage Tracking and Differentiation of Neuro 2A cells (N2a) upon exposure to Dopamine, Monosodium Glutamate and Corticosterone. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554359. |
dopamine (da) a monoamine catecholamine neurotransmitter and hormone binds to dopamine receptor, inturn, affect movement, emotions and the reward system in the brain. |
2022-05-13 |
2023-08-13 |
mouse |
| Thomas M Keck, Shreya Kelshikar, Nisha Shah, Connor McBride, Moises Ximello Sanchez, Diandra Panasis, Brianna Maslonka, Abigail Muccilli, Maria Ladik, Ebrar Akca, Sophia Ginet, Ashley Nilson, Noelia Boldizsar, R Benjamin Free, David R Sibley, Comfort A Boaten. Novel Dopamine D4 Receptor-Selective Antagonists For Neuropsychiatric Disorders. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554599. |
the neurotransmitter dopamine signals through g protein-coupled receptors that regulate a variety of neurophysiological functions, including movement, emotional regulation, motivation, and cognition. |
2022-05-13 |
2023-08-13 |
Not clear |
| Yibin Xu, Stacia Lewandowski, Christina Besad. Allosteric Dopamine transporter modulator inhibits cocaine-induced behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555950. |
the dopamine transporter (dat) is a transmembrane protein responsible for reuptake the neurotransmitter dopamine back into the presynaptic neurons. |
2022-05-13 |
2023-08-13 |
rat |
| Chen Jian-Min, Wang Zhi-Yuan, Wu Shi-Xuan, Song Rui, Wu Ning, Li Ji. Effects of Lisdexamfetamine, a Prodrug of D-Amphetamine, on Locomotion, Spatial Cognitive Processing and Neurochemical Profiles in Rats: A Comparison With Immediate-Release Amphetamine. Frontiers in psychiatry. vol 13. 2022-05-13. PMID:35558431. |
given the crucial involvement of dopamine neurotransmitter system within the medial prefrontal cortex (mpfc) in cognitive processing, microdialysis was conducted to profile the difference in neurochemical characteristics between the two drugs. |
2022-05-13 |
2023-08-13 |
rat |