| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole Newman, Imaan Benmerzoug. Characterizing the influence of Toxoplasma infection on opioid receptor expression using human neuroblastoma cells (SKNSH). FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560458. |
previous studies have shown that toxoplasmaincreases dopamine synthesis, and dopamine is an important neurotransmitter in the reward pathway, where the opioid system has been shown to play a major role in modulating this pathway. |
2022-05-13 |
2023-08-13 |
human |
| Enkhmaa Luvsannyam, Molly S Jain, Maria Kezia Lourdes Pormento, Hira Siddiqui, Angela Ria A Balagtas, Bernard O Emuze, Teresa Poprawsk. Neurobiology of Schizophrenia: A Comprehensive Review. Cureus. vol 14. issue 4. 2022-05-11. PMID:35541299. |
there is no clear link between neurotransmitter changes and the pathophysiology of schizophrenia; however, studies have shown that subcortical dopamine dysfunction is the key mechanism. |
2022-05-11 |
2023-08-13 |
Not clear |
| Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Li. Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35. RSC advances. vol 9. issue 32. 2022-05-06. PMID:35515227. |
the neurotransmitter dysfunction was mainly involved in γ-aminobutyric acid (gaba), acetyl choline (ach), glutamic acid (glu), 5-hydroxytryptamine (5-ht), dopamine (da) and norepinephrine (ne). |
2022-05-06 |
2023-08-13 |
rat |
| Suárez-Pereira I, García-Domínguez I, Bravo L, Santiago M, García-Revilla J, Espinosa-Oliva A M, Alonso-Bellido I M, López-Martín C, Pérez-Villegas E M, Armengol J A, Berrocoso E, Venero J L, de Pablos R M, Ruiz . The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior. Frontiers in cell and developmental biology. vol 10. 2022-05-02. PMID:35493109. |
in the striatum, the basal extracellular level of dopamine and potassium-evoked dopamine release decreased significantly in mice lacking casp8, clearly showing the low dopamine functioning in tissues innervated by this neurotransmitter. |
2022-05-02 |
2023-08-13 |
mouse |
| Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Ima. Hyperinsulinemia Associated Depression. Clinical medicine insights. Endocrinology and diabetes. vol 15. 2022-05-02. PMID:35494421. |
increased inflammatory cytokines have also been shown to disrupt neurotransmitter metabolism and synaptic plasticity which play a role in the development of depression via inhibiting serotonin, dopamine, melatonin, and glutamate signaling. |
2022-05-02 |
2023-08-13 |
Not clear |
| Beth Fairfield, Caterina Padulo, Nicola Mammarella, Sara Fontanella, Annalina Sarra, Fani Konstantinidou, Liborio Stuppia, Valentina Gatt. Dopamine-related polymorphisms and Affective Working Memory in aging. Neurobiology of learning and memory. 2022-04-26. PMID:35472439. |
the neurotransmitter dopamine (da) is a key regulatory component of executive functioning and dysfunction in dopaminergic circuity has been shown to result in impaired working memory. |
2022-04-26 |
2023-08-13 |
human |
| Toshiharu Nagatsu, Akira Nakashima, Hirohisa Watanabe, Shosuke Ito, Kazumasa Wakamats. Neuromelanin in Parkinson's Disease: Tyrosine Hydroxylase and Tyrosinase. International journal of molecular sciences. vol 23. issue 8. 2022-04-23. PMID:35456994. |
the main symptoms of pd are movement disorders accompanied with deficiency of neurotransmitter dopamine (da) in the striatum due to cell death of the nigrostriatal da neurons. |
2022-04-23 |
2023-08-13 |
human |
| Natalia Kurzina, Anastasia Belskaya, Arina Gromova, Alla Ignashchenkova, Raul R Gainetdinov, Anna Volnov. Modulation of Spatial Memory Deficit and Hyperactivity in Dopamine Transporter Knockout Rats Frontiers in psychiatry. vol 13. 2022-04-11. PMID:35401264. |
the dopamine neurotransmitter system is postulated to be involved in the pathogenesis of adhd. |
2022-04-11 |
2023-08-13 |
rat |
| Milica Prvulovic, Smilja Todorovic, Desanka Milanovic, Milena Jovic, Predrag Vujovic, Selma Kanazir, Aleksandra Mladenovi. Calorie restriction changes the anxiety-like behaviour of ageing male Wistar rats in an onset- and duration-dependent manner. Mechanisms of ageing and development. 2022-03-25. PMID:35331743. |
in addition, as the dopaminergic system is one of the main neurotransmitter systems involved in controlling anxiety, we examined the expression of dopamine receptors (d |
2022-03-25 |
2023-08-13 |
human |
| Peter F Liddle, Elizabeth B Liddl. Imprecise Predictive Coding Is at the Core of Classical Schizophrenia. Frontiers in human neuroscience. vol 16. 2022-03-21. PMID:35308615. |
we discuss the possibility that frequent prediction errors might promote excess release of the neurotransmitter, dopamine, thereby accounting for the occurrence of episodes of florid psychotic symptoms including delusions and hallucinations in classical schizophrenia. |
2022-03-21 |
2023-08-13 |
Not clear |
| Sevag Hamamah, Armin Aghazarian, Anthony Nazaryan, Andras Hajnal, Mihai Covas. Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203645. |
dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and motivation. |
2022-02-25 |
2023-08-13 |
Not clear |
| Gerry Leisman, Dana Sheldo. Tics and Emotions. Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35204005. |
dopamine plays a vital role in cognition and motor control and is an important neurotransmitter in the pathophysiology of other disorders such as obsessive-compulsive disorder (ocd) and attention deficit hyperactivity disorder (adhd), which tend to be comorbid with ticking disorders and are thought to use similar pathways. |
2022-02-25 |
2023-08-13 |
Not clear |
| Atieh Chizari, Rezvan Hassanpour, Saeideh Karimi-Haghighi, Ronak Azizbeigi, Somaye Mesgar, Zahra Mousavi, Abbas Haghparas. Compensatory Role of Insulin in the Extinction but Not Reinstatement of Morphine-Induced Conditioned Place Preference in the Streptozotocin-Induced Diabetic Rats. Neurochemical research. 2022-02-21. PMID:35188597. |
insulin receptors are distributed in the whole brain, including different parts of the reward circuit that modulate dopamine as the primary neurotransmitter implicated in addiction. |
2022-02-21 |
2023-08-13 |
rat |
| Christian Saleh, Agnieszka Andrykiewicz, Margret Hund-Georgiadi. Does Madopar Have a Role in the Treatment of Prolonged Disorders of Consciousness? A Call for Randomized Controlled Trials. Case reports in neurology. vol 13. issue 3. 2022-02-03. PMID:35111026. |
dopamine is an important stimulatory neurotransmitter, which plays a key role in alertness, arousal, behavior, emotion, cognition, and motor function. |
2022-02-03 |
2023-08-13 |
Not clear |
| Yang Yu, Renee Miller, Susan W Grot. A literature review of dopamine in binge eating. Journal of eating disorders. vol 10. issue 1. 2022-01-29. PMID:35090565. |
the neurotransmitter dopamine is involved in food craving, decision making, executive functioning, and impulsivity personality trait; all of which contribute to the development and maintenance of binge eating. |
2022-01-29 |
2023-08-13 |
Not clear |
| Adriana Trapani, Stefania Cometa, Elvira De Giglio, Filomena Corbo, Roberta Cassano, Maria Luisa Di Gioia, Sonia Trombino, Md Niamat Hossain, Sante Di Gioia, Giuseppe Trapani, Massimo Cones. Novel Nanoparticles Based on Pharmaceutics. vol 14. issue 1. 2022-01-21. PMID:35057043. |
although several bio-nanomaterials have been evaluated for encapsulation of neurotransmitter dopamine (da) or dopaminergic drugs in order to restore the da content in parkinsonian patients, the premature leakage of the therapeutic agent limits this approach. |
2022-01-21 |
2023-08-13 |
Not clear |
| Jia-Hui Zhong, Yan-Zhi Bi, Ya-Zhuo Kong, Zhi-Jie Lu, Li H. [Central neural mechanism of increased pain sensitivity induced by nicotine abstinence]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 6. 2021-12-28. PMID:34961870. |
then, we summarized the effects of the brain neurotransmitter release (e.g., serotonin, norepinephrine, endogenous opioids, dopamine, and γ-aminobutyric acid) and their corresponding receptor activation changes after nicotine abstinence on pain sensitivity. |
2021-12-28 |
2023-08-13 |
human |
| Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas McLaughlin, Abdalla Bowirrat, Mark Gol. A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing "Precision Behavioral Management". Psychology research and behavior management. vol 14. 2021-12-24. PMID:34949945. |
this approach includes 1) using the genetic addiction risk severity (gars, a 10 candidate polymorphic gene panel shown to predict asi-alcohol and drug severity) to assess early pre-disposition to substance use disorder; 2) using a validated reward deficiency syndrome (rds) questionnaire; 3) utilization of the comprehensive analysis of reported drugs (card™) to assess treatment compliance and abstinence from illicit drugs during treatment, and, importantly; 4) utilization of a "pro-dopamine regulator (kb220)" (via iv or oral [kb220z] delivery systems) to optimize gene expression, restore the balance of the brain reward cascade's neurotransmitter systems and prevent relapse by induction of dopamine homeostasis, and; 5) utilization of targeted dna polymorphic reward genes to direct mrna genetic expression profiling during the treatment process. |
2021-12-24 |
2023-08-13 |
Not clear |
| Allison E Hamilos, Giulia Spedicato, Ye Hong, Fangmiao Sun, Yulong Li, John Assa. Slowly evolving dopaminergic activity modulates the moment-to-moment probability of reward-related self-timed movements. eLife. vol 10. 2021-12-23. PMID:34939925. |
clues from human movement disorders have long suggested that the neurotransmitter dopamine plays a role in motor control, but how the endogenous dopaminergic system influences movement is unknown. |
2021-12-23 |
2023-08-13 |
mouse |
| Zhao-Yan Cheng, Yu-Hui Hu, Qing-Peng Xia, Chen Wang, Ling H. DRD1 agonist A-68930 improves mitochondrial dysfunction and cognitive deficits in a streptozotocin-induced mouse model. Brain research bulletin. vol 175. 2021-12-10. PMID:34284074. |
dopamine is the most abundant catecholaminergic neurotransmitter in the brain which regulates motivation, reward, movement, and cognition. |
2021-12-10 |
2023-08-13 |
mouse |