| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Tripp, Hyunjung Oh, Jean-Philippe Guilloux, Keri Martinowich, David A Lewis, Etienne Sibill. Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. The American journal of psychiatry. vol 169. issue 11. 2013-03-27. PMID:23128924. |
low levels of brain-derived neurotrophic factor (bdnf) and reduced markers for gaba function, including in the amygdala, are reported in major depression, but their contribution to subgenual anterior cingulate cortex dysfunction is not known. |
2013-03-27 |
2023-08-12 |
Not clear |
| Qiuli Liu, Margaret T T Wong-Rile. Postnatal development of brain-derived neurotrophic factor (BDNF) and tyrosine protein kinase B (TrkB) receptor immunoreactivity in multiple brain stem respiratory-related nuclei of the rat. The Journal of comparative neurology. vol 521. issue 1. 2013-03-08. PMID:22678720. |
brain-derived neurotrophic factor (bdnf) and its tyrosine protein kinase b (trkb) receptors are known to potentiate glutamatergic and attenuate gamma-aminobutyric acid (gaba)ergic neurotransmission, and bdnf is essential for respiratory development. |
2013-03-08 |
2023-08-12 |
rat |
| Emily G Waterhouse, Juan Ji An, Lauren L Orefice, Maryna Baydyuk, Guey-Ying Liao, Kang Zheng, Bai Lu, Baoji X. BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 41. 2013-01-03. PMID:23055503. |
bdnf(klox/klox) mice exhibited reduced expression of glutamic acid decarboxylase 65 (a gaba synthase), increased proliferation of progenitor cells, and impaired differentiation and maturation of newborn neurons in the sgz. |
2013-01-03 |
2023-08-12 |
mouse |
| Emily G Waterhouse, Juan Ji An, Lauren L Orefice, Maryna Baydyuk, Guey-Ying Liao, Kang Zheng, Bai Lu, Baoji X. BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 41. 2013-01-03. PMID:23055503. |
thus, our data suggest that locally synthesized bdnf in dendrites of granule cells promotes differentiation and maturation of progenitor cells in the sgz by enhancing gaba release, at least in part, from pv-expressing gabaergic interneurons. |
2013-01-03 |
2023-08-12 |
mouse |
| Daria Peleg-Raibstein, Edlira Luca, Christian Wolfru. Maternal high-fat diet in mice programs emotional behavior in adulthood. Behavioural brain research. vol 233. issue 2. 2012-12-10. PMID:22633920. |
in addition, brain-derived neurotrophic factor (bdnf) was significantly increased in the dorsal hippocampus, while gaba(a) alpha2 receptor subunit and 5-hydroxytryptamine 1a (5-ht1a) receptor showed increased levels in the ventral hippocampus. |
2012-12-10 |
2023-08-12 |
mouse |
| Citlali Trueta, Francisco F De-Migue. Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system. Frontiers in physiology. vol 3. 2012-10-02. PMID:22969726. |
the catalog of these molecules includes low molecular weight transmitters such as monoamines, acetylcholine, glutamate, gama-aminobutiric acid (gaba), adenosine-5-triphosphate (atp), and a list of peptides including substance p, brain-derived neurotrophic factor (bdnf), and oxytocin. |
2012-10-02 |
2023-08-12 |
Not clear |
| Mario Mauri, Daniela Lentini, Marta Gravati, Dana Foudah, Gerardo Biella, Barbara Costa, Mauro Toselli, Marco Parenti, Silvia Coc. Mesenchymal stem cells enhance GABAergic transmission in co-cultured hippocampal neurons. Molecular and cellular neurosciences. vol 49. issue 4. 2012-08-27. PMID:22388097. |
the enhancement of gaba synapses was impaired by the treatment with k252a, a trk/neurotrophin receptor blocker, and by trkb receptor bodies hence suggesting the involvement of bdnf as a mediator of such effects. |
2012-08-27 |
2023-08-12 |
rat |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
growth factors, such as pdgf, and bdnf, regulate the gaba phenotype by inducing the expression of gad₆₇ and stimulating the growth of cellular processes, many with growth cones that form appositions with the cell bodies and processes of other gad₆₇-positive cells. |
2012-08-03 |
2023-08-12 |
Not clear |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
the addition of bdnf, together with pdgf, increases the levels of mrna and protein for gad₆₇, as well as the high affinity gaba uptake protein, gat1. |
2012-08-03 |
2023-08-12 |
Not clear |
| Daisuke Ihara, Mamoru Fukuchi, Daisuke Honma, Ichiro Takasaki, Mitsuru Ishikawa, Akiko Tabuchi, Masaaki Tsud. Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22079160. |
neurite complexity and length were reduced not only by a blockade of cellular excitation with gaba or ca(2+) influx via l-type voltage-dependent calcium channels with nicardipine, but also by a blockade of trkb, a specific receptor for bdnf, with trkb/fc. |
2012-07-27 |
2023-08-12 |
rat |
| Daisuke Ihara, Mamoru Fukuchi, Daisuke Honma, Ichiro Takasaki, Mitsuru Ishikawa, Akiko Tabuchi, Masaaki Tsud. Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22079160. |
dm-induced bdnf eiv-ix mrna expression through the calcineurin and erk/mapk pathways, the increase of which was reduced by gaba(a) receptor activation. |
2012-07-27 |
2023-08-12 |
rat |
| Gianluigi Guidotti, Francesca Calabrese, Francesca Auletta, Jocelien Olivier, Giorgio Racagni, Judith Homberg, Marco A Riv. Developmental influence of the serotonin transporter on the expression of npas4 and GABAergic markers: modulation by antidepressant treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 3. 2012-07-19. PMID:22012473. |
one of the transcription factors regulating bdnf is the neuronal pas domain protein 4 (npas4), which regulates activity-dependent genes and neuroprotection, and has a critical role in the development of gaba synapses. |
2012-07-19 |
2023-08-12 |
rat |
| Alessandro Massella, Giulia D'Intino, Mercedes Fernández, Sandra Sivilia, Luca Lorenzini, Silvia Giatti, Roberto C Melcangi, Laura Calzà, Luciana Giardin. Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis. BMC neuroscience. vol 13. 2012-06-08. PMID:22272832. |
attention was focused on markers of myelination (mbp and pdgfαr) and neuronal distress and/or damage (gaba synthesis enzymes, gad65 and gad67, ngf, bdnf and related receptors), in two cns areas, i.e. |
2012-06-08 |
2023-08-12 |
rat |
| B Arias, M Aguilera, J Moya, P A Sáiz, H Villa, M I Ibáñez, M P García-Portillo, J Bobes, G Ortet, L Fañaná. The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits. Acta psychiatrica Scandinavica. vol 125. issue 3. 2012-06-01. PMID:21902679. |
the aims of this study were to test the individual association of the serotonin transporter gene (slc6a4), the brain-derived neurotrophic factor gene (bdnf) and the gaba(a) α(6) receptor subunit gene (gabra6) with anxiety-related traits and to explore putative gene-gene interactions in a spanish healthy sample. |
2012-06-01 |
2023-08-12 |
Not clear |
| Jennifer Rodger, Christina Mo, Tenelle Wilks, Sarah A Dunlop, Rachel M Sherrar. Transcranial pulsed magnetic field stimulation facilitates reorganization of abnormal neural circuits and corrects behavioral deficits without disrupting normal connectivity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 4. 2012-05-31. PMID:22223750. |
pmfs induced bdnf, gaba, and nnos expression in the superior colliculus and retina of wild-type and ephrin-a2a5(-/-) mice. |
2012-05-31 |
2023-08-12 |
mouse |
| Siobhan S Pattwell, Kevin G Bath, Rosalia Perez-Castro, Francis S Lee, Moses V Chao, Ipe Nina. The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396415. |
also, we observed a decrease in nmda and gaba receptor-mediated synaptic transmission in the pyramidal neurons of bdnf(met/met) mice. |
2012-04-23 |
2023-08-12 |
mouse |
| Siobhan S Pattwell, Kevin G Bath, Rosalia Perez-Castro, Francis S Lee, Moses V Chao, Ipe Nina. The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396415. |
while bdnf enhanced non-nmda receptor transmission and depressed gaba receptor transmission in the wild-type mice, both effects were absent in bdnf(met/met) mice after bdnf treatment. |
2012-04-23 |
2023-08-12 |
mouse |
| Siobhan S Pattwell, Kevin G Bath, Rosalia Perez-Castro, Francis S Lee, Moses V Chao, Ipe Nina. The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396415. |
bdnf-mediated selective reversal of the deficit in plasticity and nmda receptor transmission, but its lack of effect on gaba and non-nmda receptor transmission in bdnf(met/met) mice, suggests separate mechanisms of val66met polymorphism upon synaptic transmission. |
2012-04-23 |
2023-08-12 |
mouse |
| Young-Hwan J. Endogenous BDNF regulates inhibitory synaptic transmission in the ventromedial nucleus of the hypothalamus. Journal of neurophysiology. vol 107. issue 1. 2012-04-19. PMID:21994261. |
hence, this increased gaba drive onto sf-1 neurons may, in part, explain the cellular mechanisms that mediate the anorexigenic effects of bdnf. |
2012-04-19 |
2023-08-12 |
mouse |
| Dong Hyun Kim, Jong Min Kim, Se Jin Park, Mudan Cai, Xiaotong Liu, Seungheon Lee, Chan Young Shin, Jong Hoon Ry. GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 2. 2012-04-17. PMID:21900885. |
gaba(a) receptor blockade enhances memory consolidation by increasing hippocampal bdnf levels. |
2012-04-17 |
2023-08-12 |
mouse |