| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Saffarpour, M Shaabani, N Naghdi, M Farahmandfar, A Janzadeh, F Nasirinezha. In vivo evaluation of the hippocampal glutamate, GABA and the BDNF levels associated with spatial memory performance in a rodent model of neuropathic pain. Physiology & behavior. vol 175. 2018-02-27. PMID:28336100. |
in vivo evaluation of the hippocampal glutamate, gaba and the bdnf levels associated with spatial memory performance in a rodent model of neuropathic pain. |
2018-02-27 |
2023-08-13 |
Not clear |
| S Saffarpour, M Shaabani, N Naghdi, M Farahmandfar, A Janzadeh, F Nasirinezha. In vivo evaluation of the hippocampal glutamate, GABA and the BDNF levels associated with spatial memory performance in a rodent model of neuropathic pain. Physiology & behavior. vol 175. 2018-02-27. PMID:28336100. |
we evaluated the effect of chronic pain on the glutamate and gaba levels and bdnf expression in the ca1 region of hippocampus as a possible explanation for memory impairment related to neuropathic pain. |
2018-02-27 |
2023-08-13 |
Not clear |
| Yalin Zhang, Judith M Reichel, Cheng Han, Juan Pablo Zuniga-Hertz, Dongsheng Ca. Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight. Cell metabolism. vol 25. issue 5. 2018-02-19. PMID:28467927. |
mechanistically, astrocytic regulation of hypothalamic extracellular gaba level and therefore bdnf expression were found partly accountable. |
2018-02-19 |
2023-08-13 |
Not clear |
| Shi-Meng Zhou, Shao-Yu Guan, Le Yang, Liu-Kun Yang, Lu Wang, Hui-Fang Nie, Xiang Li, Ming-Gao Zhao, Qi Yang, Hong W. Cucurbitacin IIa exerts antidepressant-like effects on mice exposed to chronic unpredictable mild stress. Neuroreport. vol 28. issue 5. 2018-01-12. PMID:28240721. |
western blot analyses showed that cums significantly decreased brain-derived neurotrophic factor (bdnf) levels, camp-response element binding protein (creb), and calcium/calmodulin-dependent protein kinase ii (camkii) phosphorylation, and n-methyl-d-aspartate receptor subtype glun2b and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor glua1 expression in the amygdala; in addition, the expression of gamma-aminobutyric acid receptor a subunit α2 was upregulated in cums mice. |
2018-01-12 |
2023-08-13 |
mouse |
| Mason L Yeh, Rajamani Selvam, Eric S Levin. BDNF-induced endocannabinoid release modulates neocortical glutamatergic neurotransmission. Synapse (New York, N.Y.). vol 71. issue 5. 2017-12-22. PMID:28164368. |
in contrast, we have shown that bdnf attenuates inhibitory transmission by inducing postsynaptic release of ecbs that act retrogradely to suppress gaba release in layer 2/3 of somatosensory cortex. |
2017-12-22 |
2023-08-13 |
Not clear |
| Judy L Cameron, Kathie L Eagleson, Nathan A Fox, Takao K Hensch, Pat Levit. Social Origins of Developmental Risk for Mental and Physical Illness. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 45. 2017-11-20. PMID:29118206. |
moreover, els may further accelerate or delay critical periods of development, which reflect gaba circuit maturation, bdnf, and circadian |
2017-11-20 |
2023-08-13 |
mouse |
| Tony Cijsouw, Thomas Biedere. How a Piggyback Synapse Listens in to Tune Excitatory Terminals. Neuron. vol 90. issue 6. 2017-10-26. PMID:27311077. |
the results highlight presynaptic roles of mglur1 receptors and of bdnf as a retrograde signal to regulate gaba synthesis and tune transmission. |
2017-10-26 |
2023-08-13 |
Not clear |
| Hyunjung Oh, David A Lewis, Etienne Sibill. The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 13. 2017-09-11. PMID:27417517. |
together, these findings suggest that age-dependent decrease in bdnf signaling may cause synaptic alterations through an initial and preferential effect on gaba presynaptic genes. |
2017-09-11 |
2023-08-13 |
mouse |
| D A Prince, F Gu, I Parad. Antiepileptogenic repair of excitatory and inhibitory synaptic connectivity after neocortical trauma. Progress in brain research. vol 226. 2017-07-06. PMID:27323945. |
partial activation of bdnf trkb receptors with a small molecule reverses structural abnormalities in fs interneuronal terminals, increases the frequency of mipscs, and increases probability of gaba release. |
2017-07-06 |
2023-08-13 |
Not clear |
| Danko Georgiev, Toru Yoshihara, Rika Kawabata, Takurou Matsubara, Makoto Tsubomoto, Yoshio Minabe, David A Lewis, Takanori Hashimot. Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons. Schizophrenia bulletin. vol 42. issue 4. 2017-06-30. PMID:26980143. |
this gad67 deficit is accompanied by lower cortical levels of other gaba-associated transcripts, including gaba transporter-1, pv, brain-derived neurotrophic factor (bdnf), tropomyosin receptor kinase b, somatostatin, gabaa receptor α1 subunit, and kcns3 potassium channel subunit mrnas. |
2017-06-30 |
2023-08-13 |
mouse |
| Danko Georgiev, Toru Yoshihara, Rika Kawabata, Takurou Matsubara, Makoto Tsubomoto, Yoshio Minabe, David A Lewis, Takanori Hashimot. Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons. Schizophrenia bulletin. vol 42. issue 4. 2017-06-30. PMID:26980143. |
in pv neuron-specific gad67 knockout mice, increased levels of pv, bdnf, and kcns3 mrnas might be the consequence of increased neuronal activity secondary to lower gaba synthesis, whereas increased gad65 mrna might represent a compensatory response to increase gaba synthesis. |
2017-06-30 |
2023-08-13 |
mouse |
| Yung-Jen Huang, Kuan H Lee, James W Gra. Complete spinal cord injury (SCI) transforms how brain derived neurotrophic factor (BDNF) affects nociceptive sensitization. Experimental neurology. vol 288. 2017-05-12. PMID:27818188. |
in uninjured rats, bdnf reduced membrane-bound kcc2 and the inhibitory effect of the gaba |
2017-05-12 |
2023-08-13 |
rat |
| Olga Geisel, Rainer Hellweg, Christian A Mülle. Serum levels of brain-derived neurotrophic factor in alcohol-dependent patients receiving high-dose baclofen. Psychiatry research. vol 240. 2017-02-21. PMID:27107672. |
also, interactions of γ-aminobutyric acid (gaba)-ergic compounds and bdnf have been reported. |
2017-02-21 |
2023-08-13 |
Not clear |
| G Zunino, A Messina, P Sgadò, G Baj, S Casarosa, Y Bozz. Brain-derived neurotrophic factor signaling is altered in the forebrain of Engrailed-2 knockout mice. Neuroscience. vol 324. 2017-01-03. PMID:26987954. |
brain-derived neurotrophic factor (bdnf) is a crucial factor for the postnatal development of forebrain gabaergic neurons, and altered gaba signaling has been hypothesized to underlie the symptoms of asd. |
2017-01-03 |
2023-08-13 |
mouse |
| Helena Kyunghee Kim, Paula Villela Nunes, Katia C Oliveira, L Trevor Young, Beny Lafe. Neuropathological relationship between major depression and dementia: A hypothetical model and review. Progress in neuro-psychopharmacology & biological psychiatry. vol 67. 2016-12-13. PMID:26780170. |
this may be due to decreased neurogenesis from lower levels of brain-derived neurotrophic factor (bdnf), excitotoxicity from increased glutamate signaling, and lower levels of gamma-aminobutyric acid (gaba) signaling. |
2016-12-13 |
2023-08-13 |
Not clear |
| Rachel Puralewski, Georgia Vasilakis, Marianne L Sene. Sex-related factors influence expression of mood-related genes in the basolateral amygdala differentially depending on age and stress exposure. Biology of sex differences. vol 7. 2016-09-23. PMID:27660699. |
previous studies in the human postmortem brain suggest dysfunction in basolateral amygdala (bla) inhibitory gamma-aminobutyric acid (gaba) signaling and brain-derived neurotrophic factor (bdnf) function, specifically in females with mdd. |
2016-09-23 |
2023-08-13 |
human |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
adenosine a2a receptor activation is determinant for bdnf actions upon gaba and glutamate release from rat hippocampal synaptosomes. |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
we thus evaluated the role of a(2a)r on the modulatory effect of bdnf upon glutamate and gaba release from isolated hippocampal nerve terminals (synaptosomes). |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
bdnf (30 ng/ml) enhanced k(+)-evoked [(3)h]glutamate release and inhibited the k(+)-evoked [(3)h]gaba release from synaptosomes. |
2016-08-29 |
2023-08-13 |
rat |
| Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastiã. Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes. Purinergic signalling. vol 11. issue 4. 2016-08-29. PMID:26452489. |
the effect of bdnf on both glutamate and gaba release requires tonic activation of adenosine a(2a)r since for both neurotransmitters, the bdnf action was blocked by the a(2a)r antagonist sch 58261 (50 nm). |
2016-08-29 |
2023-08-13 |
rat |