| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mauro Congiu, Sarah Mondoloni, Ioannis S Zouridis, Lisa Schmors, Salvatore Lecca, Arnaud L Lalive, Kyllian Ginggen, Fei Deng, Philipp Berens, Rosa Chiara Paolicelli, Yulong Li, Andrea Burgalossi, Manuel Mamel. Plasticity of neuronal dynamics in the lateral habenula for cue-punishment associative learning. Molecular psychiatry. 2023-07-06. PMID:37414924. |
while glutamate, gaba, and serotonin release in lhb remain stable across associative learning, we observe enhanced acetylcholine signaling developing throughout conditioning. |
2023-07-06 |
2023-08-14 |
mouse |
| Huiwen Kang, Wei Zhang, Jiaru Jing, Danyang Huang, Lei Zhang, Jingyu Wang, Lin Han, Ziyan Liu, Ziyan Wang, Ai Ga. The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways. Journal of hazardous materials. vol 458. 2023-07-01. PMID:37392641. |
we found that 80 nm ps-nps could reach and cause neuronal damage in the hippocampus, and alter the expression of neuroplasticity-related molecules (5-ht, ache, gaba, bdnf and creb), and even affect the learning and memory ability of mice. |
2023-07-01 |
2023-08-14 |
mouse |
| Witold Żakowski, Piotr Zawistowsk. Neurochemistry of the mammillary body. Brain structure & function. 2023-06-28. PMID:37378855. |
the following groups of substances are reviewed: (1) classical neurotransmitters (glutamate and other excitatory transmitters, gamma-aminobutyric acid, acetylcholine, serotonin, and dopamine), (2) neuropeptides (enkephalins, substance p, cocaine- and amphetamine-regulated transcript, neurotensin, neuropeptide y, somatostatin, orexins, and galanin), and (3) other substances (calcium-binding proteins and calcium sensor proteins). |
2023-06-28 |
2023-08-14 |
rat |
| Nina Colombel, Guillaume Ferreira, Regina M Sullivan, Gérard Coureau. Dynamic developmental changes in neurotransmitters supporting infant attachment learning. Neuroscience and biobehavioral reviews. 2023-05-31. PMID:37257712. |
here we review the neural circuitry supporting this neonatal odor learning, unique compared to adults, focusing specifically on the early roles of neurotransmitters such as glutamate, gaba (gamma-aminobutyric acid), serotonin, dopamine and norepinephrine, in the olfactory bulb, the anterior piriform cortex and amygdala. |
2023-05-31 |
2023-08-14 |
Not clear |
| Jo Sourbron, Lieven Laga. Fenfluramine: a plethora of mechanisms? Frontiers in pharmacology. vol 14. 2023-05-30. PMID:37251322. |
our review highlights the importance of serotonin and sigma-1 receptor mechanisms in maintaining a balance between excitatory (glutamatergic) and inhibitory (γ-aminobutyric acid [gaba]-ergic) neural networks, and suggests that these mechanisms may represent primary pharmacological moas in seizures, non-seizure comorbidities, and sudep. |
2023-05-30 |
2023-08-14 |
Not clear |
| Josua Zimmermann, Niklaus Zölch, Rebecca Coray, Francesco Bavato, Nicole Friedli, Markus R Baumgartner, Andrea E Steuer, Antje Opitz, Annett Werner, Georg Oeltzschner, Erich Seifritz, Ann Kathrin Stock, Christian Beste, David M Cole, Boris B Quedno. Chronic 3,4-Methylenedioxymethamphetamine (MDMA) use is related to glutamate and GABA concentrations in the striatum, but not in the anterior cingulate cortex. The international journal of neuropsychopharmacology. 2023-05-26. PMID:37235749. |
however, serotonin functions are strongly entangled with glutamate as well as γ-aminobutyric acid (gaba) neurotransmission and studies in mdma-exposed rats show long-term adaptations in glutamatergic and gabaergic signaling. |
2023-05-26 |
2023-08-14 |
rat |
| Ka Wai Chan, Jennifer Hebert, Daniel Radford-Smith, Daniel C Anthony, Philip Wj Burne. Live or heat-killed probiotic administration reduces anxiety and central cytokine expression in BALB/c mice, but differentially alters brain neurotransmitter gene expression. Neuropharmacology. 2023-05-07. PMID:37150398. |
to investigate the psychotropic effects of a multi-species probiotic supplement on emotional behaviour in male balb/c mice, we explored the potential mechanisms of action relating to the temporal changes in the mrna expression of brain cytokines, growth factors, central 5ht receptor and serotonin transporter (sert) and gaba receptor in the context of probiotic induced behavioural changes. |
2023-05-07 |
2023-08-14 |
mouse |
| Wenyan Xian, Yu Deng, Yuzhe Yang, Zhaolun Tan, Chunlian Chen, Wu Li, Ruili Yan. Ameliorative Effect of Ellagic Acid on Aging in Rats with the Potential Mechanism Relying on the Gut Microbiota and Urolithin A-Producing Ability. Journal of agricultural and food chemistry. 2023-05-03. PMID:37132992. |
our results showed that ea improved cognitive impairment and hippocampal damage, increased the gaba (by 107.84-117.86%) and 5-ht (by 72.56-100.85%) levels, and suppressed the inflammatory and oxidative stress in aging rats. |
2023-05-03 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
we examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of neurotransmitters, including dopamine, serotonin, glutamate, glutamine, and gaba in the amygdala and hippocampus. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
dopamine, serotonin, glutamate, glutamine, and gaba were extracted from both the amygdala and hippocampus and were separated and quantified using a developed and validated hplc-ms/ms method. |
2023-04-28 |
2023-08-14 |
rat |
| Ping Ding, Chongdan Xiang, Xintong Li, Haibo Chen, Xiaoxia Shi, Xin Li, Chushan Huang, Yunjiang Yu, Jianying Qi, Adela Jing Li, Lijuan Zhang, Guocheng H. Photoaged microplastics induce neurotoxicity via oxidative stress and abnormal neurotransmission in zebrafish larvae (Danio rerio). The Science of the total environment. 2023-04-17. PMID:37068667. |
similarly, exposure to p-ps significantly increased neurotransmitter (5-ht, gaba, da, and ach) levels and activity of ache, chat, and che. |
2023-04-17 |
2023-08-14 |
cat |
| Ender M Coskunpinar, Seymanur Tur, Nagihan Cevher Binici, Cisel Yazan Songü. Association of GABRG3, GABRB3, HTR2A Gene Variants with Autism Spectrum Disorder. Gene. 2023-04-05. PMID:37019319. |
in this study, we focused on gamma amino butyric acid (gaba) and serotonin, which are thought to contribute to the etiology of autism; it is aimed to elucidate the mechanism of the disease by investigating variant changes in the gaba receptor subunit genes gabrb3, gabrg3 and the htr2a gene, which encodes one of the serotonin receptors. |
2023-04-05 |
2023-08-14 |
human |
| Xiaoju Liu, Haijuan Wang, Xiaoyu Wang, Yinxia Ning, Wei Liu, Jie Ga. Baixiangdan capsule and Shuyu capsule regulate anger-out and anger-in, respectively: GB1-mediated GABA can regulate 5-HT levels in multiple brain regions. Aging. vol 15. 2023-03-29. PMID:36988497. |
on this basis, gaba content in the dorsal raphe nucleus (drn) and serotonin (5-ht) contents in these brain regions were detected using elisa after various time courses (0, 1, 3, 5, and 7 days) treated with bxd and sy. |
2023-03-29 |
2023-08-14 |
rat |
| Xiaoju Liu, Haijuan Wang, Xiaoyu Wang, Yinxia Ning, Wei Liu, Jie Ga. Baixiangdan capsule and Shuyu capsule regulate anger-out and anger-in, respectively: GB1-mediated GABA can regulate 5-HT levels in multiple brain regions. Aging. vol 15. 2023-03-29. PMID:36988497. |
the improvement way is as follows: decreased abnormal increase of gaba and gb1 in the drn further mediated synaptic inhibition and increased 5-ht level in the drn, leading to increased 5-ht levels in the pfc, hypothalamus, and hippocampus. |
2023-03-29 |
2023-08-14 |
rat |
| Guanlan Liu, Israr Khan, Yuxi Li, Yun Yang, Xuerui Lu, Yafei Wang, Junxiang Li, Chunjiang Zhan. Overcoming Anxiety Disorder by Probiotic Foods (Basel, Switzerland). vol 11. issue 22. 2023-03-08. PMID:36429192. |
lzu-j-tsl6 was able to effectively increase the gaba content in the mice hippocampus (p < 0.0001) and restore some markers related to anxiety such as brain-derived neurotrophic factor (bdnf), glial fibrillary acidic protein (gfap), and 5-hydroxytryptamine (5-ht). |
2023-03-08 |
2023-08-16 |
mouse |
| Kim Ros. Psychobiotics: Are they the future intervention for managing depression and anxiety? A literature review. Explore (New York, N.Y.). 2023-03-03. PMID:36868988. |
overall, the current evidence suggests that 1) specific strains of probiotics can reduce depressive symptoms and anxiety; 2) symptoms may be reduced through one or more possible mechanisms of action, including impact on the synthesis of neurotransmitters such as serotonin and gaba, modulation of inflammatory cytokines, or enhancing stress responses through effects on stress hormones and the hpa axis; and 3) while psychobiotics may offer therapeutic benefits to manage depression and anxiety, further research, particularly human studies, is needed to better characterize their mode of action and understand optimal dosing in the context of nutritional interventions. |
2023-03-03 |
2023-08-14 |
human |
| Ewa Lepiarczyk, Łukasz Paukszto, Marta Wiszpolska, Elżbieta Łopieńska-Biernat, Agnieszka Bossowska, Mariusz Krzysztof Majewski, Marta Majewsk. Molecular Influence of Resiniferatoxin on the Urinary Bladder Wall Based on Differential Gene Expression Profiling. Cells. vol 12. issue 3. 2023-02-11. PMID:36766804. |
interestingly, rtx intravesical installation was followed by changes in the expression of genes involved in synaptic plasticity and neuromodulation, including 5-ht, h2s, glutamate, and gaba transmission. |
2023-02-11 |
2023-08-14 |
Not clear |
| Yong Chen, Dan Li, Ningcen Li, PeiYong Loh, Yi Guo, Xiyou Hu, Jingyu Zhang, Baomin Dou, Lifen Wang, Chaobo Yang, Tao Guo, Shuangli Chen, Zhen Liu, Bo Chen, Zelin Che. Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain. Frontiers in neurology. vol 14. 2023-02-09. PMID:36756246. |
it can also activate the downstream pain inhibitory pathway by upregulating opioid peptide (β-endorphin), mor receptors, gaba and gaba receptors, bi-directional regulating 5-hydroxytryptamine (5-ht) and its receptors (upregulate 5-ht 1a and downregulate 5-ht7r) and stimulating hypothalamic appetite-modifying neurons. |
2023-02-09 |
2023-08-14 |
Not clear |
| Laura C Fox, Jamie L Scholl, Michael J Watt, Gina L Forste. GABA Neuroscience. 2023-02-03. PMID:36736883. |
the hippocampus and amygdala are implicated in stress responses and anxiety, and within these regions, gamma-aminobutyric acid (gaba) and serotonin modulate output and behavioral expression. |
2023-02-03 |
2023-08-14 |
Not clear |
| Heng-Chang Zhang, Yang Du, Lei Chen, Zeng-Qiang Yuan, Yong Chen. MicroRNA Schizophrenia: Etiology, Biomarkers and Therapeutic Targets. Neuroscience and biobehavioral reviews. 2023-01-27. PMID:36707012. |
it is now commonly believed that in addition to the traditional dopaminergic mesolimbic pathway, the etiology of schizophrenia also includes neuronal networks, such as glutamate, gaba, serotonin, bdnf, oxidative stress, inflammation and the immune system. |
2023-01-27 |
2023-08-14 |
human |