| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonaid Ahmad Malik, Zahid Yaseen, Lahari Thotapalli, Sakeel Ahmed, Mohd Farooq Shaikh, Sirajudheen Anwa. Understanding translational research in schizophrenia: A novel insight into animal models. Molecular biology reports. 2023-01-24. PMID:36692676. |
dopamine, glutamate, gaba, and serotonin are the neurotransmitters involved in the pathophysiology of schizophrenia. |
2023-01-24 |
2023-08-14 |
Not clear |
| Yifeng Shi, Mengqi Wang, Linglong Xiao, Luolan Gui, Wen Zheng, Lin Bai, Bo Su, Bin Li, Yangyang Xu, Wei Pan, Jie Zhang, Wei Wan. Potential therapeutic mechanism of deep brain stimulation of the nucleus accumbens in obsessive-compulsive disorder. Frontiers in cellular neuroscience. vol 16. 2023-01-23. PMID:36687525. |
furthermore, we found that the local levels of monoamines [dopamine (da) and serotonin (5-ht)] and amino acids [glutamate (glu) and gamma-aminobutyric acid (gaba)] in the nac were increased in ocd status, and that the expression of the two types of da receptors in the nac exhibited an opposite change. |
2023-01-23 |
2023-08-14 |
rat |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Corrigendum to' Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice' [Journal of Ginseng Research Volume 46, Issue 6, November 2022, Pages 819-829]. Journal of ginseng research. vol 47. issue 1. 2023-01-16. PMID:36644391. |
corrigendum to' anxiolytic effect of korean red ginseng through upregulation of serotonin and gaba transmission and bdnf expression in immobilized mice' [journal of ginseng research volume 46, issue 6, november 2022, pages 819-829]. |
2023-01-16 |
2023-08-14 |
mouse |
| Yilu Sun, Jia Zhao, Jianhui Ron. Dissecting the molecular mechanisms underlying the antidepressant activities of herbal medicines through the comprehensive review of the recent literatures. Frontiers in psychiatry. vol 13. 2023-01-09. PMID:36620687. |
the pathophysiology of depression is tightly regulated by the biosynthesis, transport and signaling of neurotransmitters [e.g., serotonin, norepinephrine, dopamine, or γ-aminobutyric acid (gaba)] in the central nervous system. |
2023-01-09 |
2023-08-14 |
Not clear |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
social isolation also caused a reduction of noradrenaline, serotonin and gaba levels, together with an increase of serotonin turnover and glutamate levels in the amygdala of isolated animals. |
2023-01-02 |
2023-08-14 |
human |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Djawad Radjabzadeh, Jos A Bosch, André G Uitterlinden, Aeilko H Zwinderman, M Arfan Ikram, Joyce B J van Meurs, Annemarie I Luik, Max Nieuwdorp, Anja Lok, Cornelia M van Duijn, Robert Kraaij, Najaf Ami. Gut microbiome-wide association study of depressive symptoms. Nature communications. vol 13. issue 1. 2022-12-06. PMID:36473852. |
these bacteria are known to be involved in the synthesis of glutamate, butyrate, serotonin and gamma amino butyric acid (gaba), which are key neurotransmitters for depression. |
2022-12-06 |
2023-08-14 |
human |
| Carla V Argañaraz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England). 2022-12-02. PMID:36458556. |
selective refinement of glutamate and gaba synapses on dorsal raphe 5-ht neurons during postnatal life. |
2022-12-02 |
2023-08-14 |
mouse |
| Carla V Argañaraz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England). 2022-12-02. PMID:36458556. |
we investigated in mice the postnatal trajectory of glutamate and gaba synaptic inputs to dorsal raphe nucleus (drn) 5-ht neurons, the main source of forebrain 5-ht. |
2022-12-02 |
2023-08-14 |
mouse |
| Paul Pålsson, Jolanta Guldberg, Jenny M Gustafsson, Harald Aif. Coma, Severe Hypotension, and Pinpoint Pupils After Olanzapine Intoxication in the Intensive Care Unit with Symptom Reversal After Administration of Flumazenil. The American journal of case reports. vol 23. 2022-12-01. PMID:36451528. |
olanzapine mainly effects dopamine, serotonin, a1-adrenergic, histamine, and muscarinic receptors, but a low affinity to gaba and benzodiazepine sites can perhaps explain the observed effect. |
2022-12-01 |
2023-08-14 |
Not clear |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research. vol 46. issue 6. 2022-10-31. PMID:36312738. |
anxiolytic effect of korean red ginseng through upregulation of serotonin and gaba transmission and bdnf expression in immobilized mice. |
2022-10-31 |
2023-08-14 |
mouse |
| Bich Phuong Bui, Phuong Linh Nguyen, Ha Thi Thu Do, Jungsook Ch. Anxiolytic effect of Korean Red Ginseng through upregulation of serotonin and GABA transmission and BDNF expression in immobilized mice. Journal of ginseng research. vol 46. issue 6. 2022-10-31. PMID:36312738. |
the present study investigated the effect of krg on immobilization-induced anxiety-like behaviors in mice and explored the involvement of the serotonin and gaba systems and bdnf in the anxiolytic action. |
2022-10-31 |
2023-08-14 |
mouse |
| Susen Becker, Anja Schulz, Sophia Kreyer, Jan Dreßler, Angelika Richter, Christin Helmschrod. Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry. Talanta. vol 253. 2022-10-08. PMID:36208557. |
the quantitative analysis of 16 neurotransmitters and metabolites, including serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), melatonin (me), dopamine (da), levodopa (l-dopa), 3-methoxytyramine (3-mt), norepinephrine (ne), epinephrine (ep), homovanillinic acid (hva), acetylcholine (ach), deoxy carnitine (iso-ach), choline (ch), and ɣ-aminobutyric acid (gaba), adenosine (ade), glutamine (gln), and glutamic acid (glu) was achieved within a chromatographic separation time of 6.5 min by the application of a biphenyl column coupled to an api-qtrap 5500 (ab sciex) mass spectrometer. |
2022-10-08 |
2023-08-14 |
mouse |
| Susen Becker, Anja Schulz, Sophia Kreyer, Jan Dreßler, Angelika Richter, Christin Helmschrod. Sensitive and simultaneous quantification of 16 neurotransmitters and metabolites in murine microdialysate by fast liquid chromatography-tandem mass spectrometry. Talanta. vol 253. 2022-10-08. PMID:36208557. |
basal extracellular concentrations of the following analytes: 5-ht, 5-hiaa, me, da, 3-mt, hva, ach, iso-ach, ch, gaba, ade, gln, and glu were determined in the striatum of mice with a md flow rate of 0.5 μl/min. |
2022-10-08 |
2023-08-14 |
mouse |
| Fengrong Chen, Yu Xu, Kai Shi, Zunyue Zhang, Zhenrong Xie, Hongjin Wu, Yuru Ma, Yong Zhou, Cheng Chen, Jiqing Yang, Yuan Wang, Trevor W Robbins, Kunhua Wang, Juehua Y. Multi-omics study reveals associations among neurotransmitter, extracellular vesicle-derived microRNA and psychiatric comorbidities during heroin and methamphetamine withdrawal. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 155. 2022-09-22. PMID:36137407. |
using weighted gene co-expression network analysis, a series of known, conserved, and novel exosomal mirnas were identified as being associated with the severity of anxiety and depression, as well as the concentrations of neurotransmitters gaba, choline, and serotonin. |
2022-09-22 |
2023-08-14 |
human |
| Wenfei Wang, Yichun Wang, Qiuting Guo, Huiting Li, Zhaoqiang Wang, Jia Li, Taotao Li, Tiantian Tang, Yujiao Wang, Yanzhuo Jia, Yao Wang, Junbo Zou, Yajun Shi, Dongyan Guo, Ming Yang, Xiaofei Zhang, Jing Su. Valerian essential oil for treating insomnia Frontiers in nutrition. vol 9. 2022-08-22. PMID:35990355. |
valerian essential oil was given orally for treatment and the contents of 5-hydroxytryptamine receptor 1 a (5-ht1ar), γ-aminobutyric acid (gaba), cyclic adenosine monophosphate (camp), and protein kinase a (pka) in the hippocampus of rats in each group were detected by enzyme-linked immunosorbent assay (elisa), western blot, polymerase chain reaction (pcr), and immunohistochemistry. |
2022-08-22 |
2023-08-14 |
rat |
| Wenfei Wang, Yichun Wang, Qiuting Guo, Huiting Li, Zhaoqiang Wang, Jia Li, Taotao Li, Tiantian Tang, Yujiao Wang, Yanzhuo Jia, Yao Wang, Junbo Zou, Yajun Shi, Dongyan Guo, Ming Yang, Xiaofei Zhang, Jing Su. Valerian essential oil for treating insomnia Frontiers in nutrition. vol 9. 2022-08-22. PMID:35990355. |
following pathway activation, we propose that the core gene protein kinase pka activates the serotonergic synapse signal pathway to increase the expression of 5-ht and gaba, thus improving insomnia symptoms and alleviating anxiety. |
2022-08-22 |
2023-08-14 |
rat |
| Anna Grete Wessel. Influence of the Gut Microbiome on Feed Intake of Farm Animals. Microorganisms. vol 10. issue 7. 2022-07-27. PMID:35889024. |
based on current evidence, the major mediators appear to be short-chain fatty acids (scfa), peptide hormones such as peptide yy (pyy) and glucagon-like peptide-1 (glp-1), as well as the amino acid tryptophan with the associated neurotransmitter serotonin, dopamine and γ-aminobutyrate (gaba). |
2022-07-27 |
2023-08-14 |
Not clear |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Zuzanna Szych, Iwona Majcher-Maślanka, Monika Herian, Marzena Maćkowiak, Krystyna Gołembiowsk. Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743159. |
ketamine (10 mg/kg) and psilocybin (2 and 10 mg/kg) increased dopamine, serotonin, glutamate and gaba extracellular levels in the frontal cortex, while psilocybin also increased gaba in the reticular nucleus of the thalamus. |
2022-06-24 |
2023-08-14 |
rat |
| Waisley Yang, Rohit Singla, Oshin Maheshwari, Christine J Fontaine, Joana Gil-Mohape. Alcohol Use Disorder: Neurobiology and Therapeutics. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625928. |
ethanol exerts its toxicity through changes to multiple neurotransmitter systems, including serotonin, dopamine, gamma-aminobutyric acid, glutamate, acetylcholine, and opioid systems. |
2022-05-28 |
2023-08-13 |
Not clear |