| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ottavio Gandolfi, Manuela Voltattorni, Renato Gaggi, Rossella Dall'Oli. Repeated administration of the novel antipsychotic olanzapine does not modulate NMDA-sensitive glutamate and 5HT2 serotonin receptors in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 6. 2004-03-23. PMID:12743679. |
since the binding of the radiolabelled channel blocker [3h]-mk801 is generally considered an affordable index of n-methyl-d-aspartate (nmda)-sensitive glutamate receptor activation, we examined the effects of clinically effective treatment (3 weeks, daily administration) of the atypical antipsychotic drug olanzapine (32 micromol/kg/5 ml) on the specific binding of [3h]-mk801 specific binding and on the strychnine-insensitive glycine sites (glycine b) in synaptic plasma membranes (spm) prepared from the medial prefrontal cortex (mpfc) of rats sacrificed after different (24, 60, 120 h) washout periods. |
2004-03-23 |
2023-08-12 |
rat |
| T Abekawa, M Honda, K Ito, T Koyam. Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats. Psychopharmacology. vol 169. issue 3-4. 2004-02-23. PMID:12898123. |
this study examined the effects of a novel thiazole derivative, nra0045 which potently antagonizes not only dopamine d(4) receptors but also 5-ht(2a) and alpha(1) adrenaline receptors, and nra0160, a selective dopamine d(4) receptor antagonist, on pcp-induced abnormal behavior, and accompanying increases in extracellular levels of glutamate in the medial prefrontal cortex. |
2004-02-23 |
2023-08-12 |
rat |
| Daniel S Lorrain, Hervé Schaffhauser, Una C Campbell, Christopher S Baccei, Lucia D Correa, Blake Rowe, Dana E Rodriguez, Jeffery J Anderson, Mark A Varney, Anthony B Pinkerton, Jean-Michel Vernier, Linda J Bristo. Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 9. 2003-10-06. PMID:12825094. |
following our initial observation on ne release, we conducted a series of microinjection experiments to reveal that the inhibitory effects of ly379268 on vhipp ne release may be linked to glutamate transmission within the medial prefrontal cortex. |
2003-10-06 |
2023-08-12 |
Not clear |
| Mark R Stefani, Karyn Groth, Bita Moghadda. Glutamate receptors in the rat medial prefrontal cortex regulate set-shifting ability. Behavioral neuroscience. vol 117. issue 4. 2003-09-09. PMID:12931958. |
glutamate receptors in the rat medial prefrontal cortex regulate set-shifting ability. |
2003-09-09 |
2023-08-12 |
rat |
| D S Lorrain, C S Baccei, L J Bristow, J J Anderson, M A Varne. Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617973. |
previous studies have shown that the metabotropic glutamate receptor (mglur)2/3 agonist ly354740 attenuated glutamate release in medial prefrontal cortex (mpfc) induced by the non-competitive n-methyl-d-aspartate (nmda) receptor antagonist phencyclidine. |
2003-05-05 |
2023-08-12 |
human |
| Hyun S Lee, Myung A Kim, Rita J Valentino, Barry D Waterhous. Glutamatergic afferent projections to the dorsal raphe nucleus of the rat. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560111. |
phaseolus vulgaris leucoagglutinin anterograde tracing studies confirmed that the medial prefrontal cortex provides the major afferent input to each subdivision of the dr. double-labeling studies combining wg tracing and glutamate immunostaining indicated that the medial prefrontal cortex, various hypothalamic nuclei including perifornical, lateral, and arcuate nuclei, and several medullary regions such as lateral and medial parabrachial nuclei, and laterodorsal tegmental nucleus provide the major glutamatergic input to each subregion of the dr. |
2003-04-28 |
2023-08-12 |
rat |
| Jonathan C Gewirtz, Andrew C Chen, Rose Terwilliger, Ronald C Duman, Gerard J Mare. Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors. Pharmacology, biochemistry, and behavior. vol 73. issue 2. 2003-02-05. PMID:12117585. |
recent studies have also shown that activation of metabotropic glutamate group ii (mglu2/3) receptors suppresses 5-ht(2a) receptor-stimulated excitatory postsynaptic potentials/currents (epsp/cs) in pyramidal neurons in medial prefrontal cortex. |
2003-02-05 |
2023-08-12 |
Not clear |
| Gretchen Neigh-McCandless, B Adar Kravitz, Martin Sarter, John P Brun. Stimulation of cortical acetylcholine release following blockade of ionotropic glutamate receptors in nucleus accumbens. The European journal of neuroscience. vol 16. issue 7. 2002-12-30. PMID:12405986. |
rats were implanted with a dialysis probe in the medial prefrontal cortex to measure changes in cortical acetylcholine efflux and in the ipsilateral nucleus accumbens to locally manipulate glutamate receptor activity. |
2002-12-30 |
2023-08-12 |
rat |
| Y Suzuki, E Jodo, S Takeuchi, S Niwa, Y Kayam. Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons in freely moving rats. Neuroscience. vol 114. issue 3. 2002-12-20. PMID:12220577. |
recent studies have reported that acute administration of the psychotomimetic drug phencyclidine results in considerable increases in the amounts of both extracellular glutamate and dopamine in the medial prefrontal cortex (mpfc). |
2002-12-20 |
2023-08-12 |
rat |
| W-R Wu, N Li, B A Sor. Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors. Neuroscience. vol 114. issue 2. 2002-11-26. PMID:12204218. |
these results suggest a potent influence of glutamate via alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors on extracellular dopamine in the medial prefrontal cortex, and these receptors may regulate dopamine release through a presynaptic mechanism. |
2002-11-26 |
2023-08-12 |
Not clear |
| Kyle Frantz, Michael Harte, Urban Ungerstedt, William T O' Conno. A dual probe characterization of dialysate amino acid levels in the medial prefrontal cortex and ventral tegmental area of the awake freely moving rat. Journal of neuroscience methods. vol 119. issue 2. 2002-11-26. PMID:12323414. |
dual probe microdialysis was employed to characterize the origins of dialysate glutamate, aspartate and gamma-aminobutyric acid (gaba) in the medial prefrontal cortex (mpfc) and to investigate functional interactions between the mpfc and ventral tegmental area (vta) in awake, freely moving rats. |
2002-11-26 |
2023-08-12 |
rat |
| Adena L Svingos, Eric E O Colag. Kappa-Opioid and NMDA glutamate receptors are differentially targeted within rat medial prefrontal cortex. Brain research. vol 946. issue 2. 2002-11-12. PMID:12137930. |
kappa-opioid and nmda glutamate receptors are differentially targeted within rat medial prefrontal cortex. |
2002-11-12 |
2023-08-12 |
rat |
| Adena L Svingos, Eric E O Colag. Kappa-Opioid and NMDA glutamate receptors are differentially targeted within rat medial prefrontal cortex. Brain research. vol 946. issue 2. 2002-11-12. PMID:12137930. |
activation of kappa-opioid receptors (kor) in the medial prefrontal cortex (mpfc) modulates excitatory transmission, which may involve interactions with n-methyl-d-aspartate (nmda) glutamate receptors. |
2002-11-12 |
2023-08-12 |
rat |
| S Otani, H Daniel, M Takita, F Crépe. Long-term depression induced by postsynaptic group II metabotropic glutamate receptors linked to phospholipase C and intracellular calcium rises in rat prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978820. |
we have previously shown (otani et al., 1999b) that bath application of (2s,2'r,3'r)-2-(2',3'-dicarboxycyclopropyl)glycine (dcg iv), the agonist of group ii metabotropic glutamate receptors (mglurs), induces postsynaptic ca2+-dependent long-term depression (ltd) of layer i-ii to layer v pyramidal neuron glutamatergic synapses of rat medial prefrontal cortex. |
2002-05-20 |
2023-08-12 |
rat |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing ampa receptor-mediated glutamate transmission in the nucleus accumbens. |
2002-04-08 |
2023-08-12 |
human |
| Masatoshi Takita, Takahiro Kawashima, Hidekazu Kaneko, Shinya S Suzuki, Hiroshi Yoko. Sensitization of glutamate release and N-methyl-D-aspartate receptor response by transient dopamine pretreatment in prefrontal cortex of rats. Neuroscience letters. vol 317. issue 2. 2002-03-19. PMID:11755249. |
we studied biochemically the effect of transient dopamine pretreatment on the regulation of glutamate transmission in medial prefrontal cortex of rats in vivo and in vitro. |
2002-03-19 |
2023-08-12 |
rat |
| P Celada, M V Puig, J M Casanovas, G Guillazo, F Artiga. Control of dorsal raphe serotonergic neurons by the medial prefrontal cortex: Involvement of serotonin-1A, GABA(A), and glutamate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11739599. |
control of dorsal raphe serotonergic neurons by the medial prefrontal cortex: involvement of serotonin-1a, gaba(a), and glutamate receptors. |
2002-01-23 |
2023-08-12 |
rat |
| G J Marek, R A Wright, J C Gewirtz, D D Schoep. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex. Neuroscience. vol 105. issue 2. 2001-12-07. PMID:11672605. |
these thalamic lesions significantly decreased the amount of binding to either mu-opioid or metabotropic glutamate 2/3 receptors in the prelimbic region of the medial prefrontal cortex as expected from previous evidence that these agonists for these receptors suppress serotonin-induced excitatory postsynaptic currents by a presynaptic mechanism. |
2001-12-07 |
2023-08-12 |
rat |
| L B Kozell, C K Meshu. The effects of acute or repeated cocaine administration on nerve terminal glutamate within the rat mesolimbic system. Neuroscience. vol 106. issue 1. 2001-12-04. PMID:11564413. |
on the challenge day, most (75%) animals that received cocaine repeatedly showed a heightened locomotor response to cocaine compared to the first day of cocaine administration, and were considered behaviorally sensitized.three days after the challenge, glutamate immunogold labeling was quantified in nerve terminals making asymmetrical synaptic contacts within the core and shell of the nucleus accumbens, ventral tegmental area and medial prefrontal cortex. |
2001-12-04 |
2023-08-12 |
rat |
| H Kawahara, Y Kawahara, B H Westerin. The noradrenaline-dopamine interaction in the rat medial prefrontal cortex studied by multi-probe microdialysis. European journal of pharmacology. vol 418. issue 3. 2001-07-05. PMID:11343687. |
application to the locus coeruleus (during 10 min) of the glutamate receptor agonists n-methyl-d-aspartate (nmda) (300 microm) or kainate (100 microm) strongly increased extracellular noradrenaline and dopamine levels in the ipsilateral medial prefrontal cortex. |
2001-07-05 |
2023-08-12 |
rat |