All Relations between glutamate and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Akiko Shimamoto, Virginie Rappeneau, Havisha Munjal, Tonie Farris, Christopher Davis, Alicia Wilson, Malcolm Edwards, Cindy Moore, Collin Reynolds, Charles K Meshu. Glutamate-Glutamine Transfer and Chronic Stress-Induced Sex Differences in Cocaine Responses. Neuroscience. vol 391. 2019-02-27. PMID:30240589. our previous findings revealed sex-dependent changes in extracellular levels of glutamate (glu) and glutamine (gln) in the nucleus accumbens (nac) in long-evans rats that were exposed to 21 days of chronic social defeat stress (csds), which models md. 2019-02-27 2023-08-13 rat
Michael T Stefanik, Courtney Sakas, Dennis Lee, Marina E Wol. Ionotropic and metabotropic glutamate receptors regulate protein translation in co-cultured nucleus accumbens and prefrontal cortex neurons. Neuropharmacology. vol 140. 2019-02-20. PMID:30077883. ionotropic and metabotropic glutamate receptors regulate protein translation in co-cultured nucleus accumbens and prefrontal cortex neurons. 2019-02-20 2023-08-13 Not clear
Carly N Logan, Amber L LaCrosse, Lori A Knacksted. Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement. Neuropharmacology. vol 135. 2019-02-04. PMID:29567092. nucleus accumbens glt-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement. 2019-02-04 2023-08-13 rat
Yusuf S Althobaiti, Fahad S Alshehri, Alqassem Y Hakami, Alaa M Hammad, Youssef Sar. Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. Journal of molecular neuroscience : MN. vol 67. issue 1. 2019-01-31. PMID:30471010. in addition, we examined the expression of glt-1, xct, and glast as well as metabotropic glutamate receptor (mglur2/3) in the nucleus accumbens (nac) shell, nac core, and dorsomedial prefrontal cortex (dmpfc). 2019-01-31 2023-08-13 rat
Megan L Fitzgerald, Virginia M Picke. Adolescent isolation rearing produces a prepulse inhibition deficit correlated with expression of the NMDA GluN1 subunit in the nucleus accumbens. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29779156. to gain insight into the neurobiological correlates of adolescent adversity, we conducted electron microscopic immunolabeling of dopamine d1 receptors (d1rs) and the glun1 subunit of glutamate nmda receptors in the acb of isolation-reared (ir) adult male rats. 2018-12-11 2023-08-13 rat
Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowsk. The Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats. Neurotoxicity research. vol 34. issue 3. 2018-11-06. PMID:29713996. in vivo microdialysis in adult rats showed an increase in dopamine (da), 5-ht, and glutamate release in the nucleus accumbens and frontal cortex but not in the striatum in response to challenge dose in animals pretreated with mephedrone in adolescence. 2018-11-06 2023-08-13 mouse
Jeremy S Lum, Bo Pan, Chao Deng, Xu-Feng Huang, Lezanne Ooi, Kelly A Newel. Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol. Psychiatry research. vol 260. 2018-11-05. PMID:29195167. group 1 metabotropic glutamate receptors (mglurs) and their endogenous modulators, norbin and homer1, are regulated by d2 receptor activity, particularly within the nucleus accumbens (nac), a target region of aripiprazole and haloperidol. 2018-11-05 2023-08-13 rat
Jiaojiao Song, Ming Chen, Yi Dong, Bin Lai, Ping Zhen. Chronic morphine selectively sensitizes the effect of D1 receptor agonist on presynaptic glutamate release in basolateral amygdala neurons that project to prelimbic cortex. Neuropharmacology. vol 133. 2018-11-05. PMID:29427651. using retrogradely labelling technique combined with whole-cell patch-clamp methods, our results showed that (1) chronic morphine sensitized the effect of d1 receptor agonist on presynaptic glutamate release in bla neurons that projected to the prelimbic cortex (prl), but had no influence on that in bla neurons that projected to the nucleus accumbens (nac) or the ca1 of the hippocampus; (2) chronic morphine sensitized the effect of d1 receptor agonist on action potential firing in bla neurons that projected to the prl, but without affecting the intrinsic excitability and the sensitivity of postsynaptic glutamate receptors to glutamate in bla neurons that projected to the prl. 2018-11-05 2023-08-13 Not clear
Katherine R Tonn Eisinger, Erin B Larson, Marissa I Boulware, Mark J Thomas, Paul G Mermelstei. Membrane estrogen receptor signaling impacts the reward circuitry of the female brain to influence motivated behaviors. Steroids. vol 133. 2018-10-30. PMID:29195840. this review outlines how membrane-localized estrogen receptors affect metabotropic glutamate receptor signaling within the rodent nucleus accumbens. 2018-10-30 2023-08-13 Not clear
Juhwan Kim, Sueun Lee, Sohi Kang, Tae-Il Jeon, Man-Jong Kang, Tae-Hoon Lee, Yong Sik Kim, Key-Sun Kim, Heh-In Im, Changjong Moo. Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29754475. regulator of g-protein signaling 4 (rgs4) controls morphine reward by glutamate receptor activation in the nucleus accumbens of mouse brain. 2018-10-30 2023-08-13 mouse
Matthew Hearing, Nicholas Graziane, Yan Dong, Mark J Thoma. Opioid and Psychostimulant Plasticity: Targeting Overlap in Nucleus Accumbens Glutamate Signaling. Trends in pharmacological sciences. vol 39. issue 3. 2018-10-24. PMID:29338873. opioid and psychostimulant plasticity: targeting overlap in nucleus accumbens glutamate signaling. 2018-10-24 2023-08-13 Not clear
Chuchu Qi, Baolin Guo, Keke Ren, Han Yao, Mengmeng Wang, Tangna Sun, Guohong Cai, Haiying Liu, Rui Li, Ceng Luo, Wenting Wang, Shengxi W. Chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens. Molecular pain. vol 14. 2018-10-22. PMID:29770746. chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens. 2018-10-22 2023-08-13 mouse
Ji Hoon Yoo, Vivien Zell, Navarre Gutierrez-Reed, Johnathan Wu, Reed Ressler, Mohammad Ali Shenasa, Alexander B Johnson, Kathryn H Fife, Lauren Faget, Thomas S Hnask. Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement. Nature communications. vol 7. 2018-09-24. PMID:27976722. whole-cell recordings reveal epscs following stimulation of vta glutamate terminals in the nucleus accumbens or local vta collaterals; but reveal both excitatory and monosynaptic inhibitory currents in the ventral pallidum and lateral habenula, though the net effects on postsynaptic firing in each region are consistent with the observed rewarding behavioural effects. 2018-09-24 2023-08-13 mouse
Xi-Long Liu, Long Li, Jian-Neng Li, Ji-Hua Tang, Jia-Hui Rong, Bo Liu, Ze-Xuan H. Quantifying absolute glutamate concentrations in nucleus accumbens of prescription opioid addicts by using Brain and behavior. vol 7. issue 8. 2018-07-13. PMID:28828225. quantifying absolute glutamate concentrations in nucleus accumbens of prescription opioid addicts by using the diagnosis of psychoactive substance use disorders has been based primarily on descriptive, symptomatic checklist criteria. 2018-07-13 2023-08-13 Not clear
Ronald Kim, Marian T Sepulveda-Orengo, Kati L Healey, Emily A Williams, Kathryn J Reissne. Regulation of glutamate transporter 1 (GLT-1) gene expression by cocaine self-administration and withdrawal. Neuropharmacology. vol 128. 2018-07-13. PMID:28919080. downregulation of the astroglial glutamate transporter glt-1 is observed in the nucleus accumbens (nac) following administration of multiple drugs of abuse. 2018-07-13 2023-08-13 rat
Christine Winter, Dana M Greene, Paraskevi Mavrogiorgou, Helge Schaper, Reinhard Sohr, Abel Bult-Ito, Georg Jucke. Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive-compulsive disorder. Behavioural brain research. vol 337. 2018-06-08. PMID:28916503. the neurochemical investigation of several brain regions of the corticostriato-thalamocortical circuity, i.e., nucleus caudatus (cpu), nucleus accumbens (nac), globus pallidus (gp), hippocampus (hpc), amygdala (am), ventral tegmental area (vta) and substantia nigra (sn) was performed by electrochemical (serotonin and dopamine) and fluorescence (glutamate and gaba) hplc detection. 2018-06-08 2023-08-13 mouse
Christina N Nona, José N Nobreg. A role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol. Behavioural brain research. vol 336. 2018-06-01. PMID:28919158. a role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol. 2018-06-01 2023-08-13 mouse
Christina N Nona, José N Nobreg. A role for nucleus accumbens glutamate in the expression but not the induction of behavioural sensitization to ethanol. Behavioural brain research. vol 336. 2018-06-01. PMID:28919158. here, we examined whether this variability might be differentially associated with nucleus accumbens (nac) glutamate processes. 2018-06-01 2023-08-13 mouse
Florence Allain, David C S Roberts, Daniel Lévesque, Anne-Noël Samah. Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation. Neuropharmacology. vol 117. 2018-05-03. PMID:28137451. this addiction-relevant phenotype was accompanied by enhanced functional activity of metabotropic glutamate group ii receptors (mglur2/3s) in the prelimbic cortex and nucleus accumbens. 2018-05-03 2023-08-13 rat
Alaa M Hammad, Yusuf S Althobaiti, Sujan C Das, Youssef Sar. Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. Molecular and cellular neurosciences. vol 82. 2018-04-24. PMID:28442364. cocaine exposure has been shown to induce a dysregulation in glutamate homeostasis and a decrease in the expression of glt-1 and xct in the nucleus accumbens (nac). 2018-04-24 2023-08-13 rat