| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chelsea N Brown, Elissa K Fultz, Sami Ferdousian, Sarina Rogers, Elijah Lustig, Ariana Page, John R Shahin, Daniel M Flaherty, Georg Von Jonquieres, Camron D Bryant, Tod E Kippin, Karen K Szumlinsk. Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32116834. |
recently, we discovered an association between genetic vulnerability to ma-taking and increased expression of the glutamate receptor scaffolding protein homer2 within both the shell and core subregions of the nucleus accumbens (nac) and demonstrated a necessary role for homer2 within the shell subregion in ma reward and reinforcement in mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Ilse Delint-Ramirez, Amir Segev, Asha Pavuluri, David W Self, Saïd Kourric. Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32760242. |
the consequence of repeated cocaine exposure and prolonged abstinence on glutamate receptor expression in the nucleus accumbens has been extensively studied. |
2020-09-28 |
2023-08-13 |
Not clear |
| Smriti Mongia, Tsuyoshi Yamaguchi, Bing Liu, Shiliang Zhang, Huiling Wang, Marisela Morale. The Ventral Tegmental Area has calbindin neurons with the capability to co-release glutamate and dopamine into the nucleus accumbens. The European journal of neuroscience. vol 50. issue 12. 2020-09-23. PMID:31215698. |
the ventral tegmental area has calbindin neurons with the capability to co-release glutamate and dopamine into the nucleus accumbens. |
2020-09-23 |
2023-08-13 |
rat |
| Erik J Garcia, David L Arndt, Mary E Cai. Dynamic interactions of ceftriaxone and environmental variables suppress amphetamine seeking. Brain research. vol 1712. 2020-09-11. PMID:30716289. |
extrasynaptic glutamate within the nucleus accumbens (nac) is a driver of relapse. |
2020-09-11 |
2023-08-13 |
rat |
| Robert A Waeiss, Christopher P Knight, Eric A Engleman, Sheketha R Hauser, Zachary A Rod. Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naïve Wistar rats. Journal of neurochemistry. vol 152. issue 5. 2020-06-30. PMID:31721205. |
drug exposure through direct infusion into the posterior ventral tegmental area (pvta) stimulated release of glutamate and dopamine in the nucleus accumbens (nac) shell, which was quantified through high-performance liquid chromatography. |
2020-06-30 |
2023-08-13 |
rat |
| Meriem Haddar, Kyosuke Uno, Kohei Hamatani, Shin-Ichi Muramatsu, Atsumi Nitt. Regulatory system of mGluR group II in the nucleus accumbens for methamphetamine-induced dopamine increase by the medial prefrontal cortex. Neuropsychopharmacology reports. vol 39. issue 3. 2020-06-29. PMID:31283871. |
shati/nat8l overexpression in the mpfc expressed lower levels of both glutamate and dopamine (da) in the nucleus accumbens (nac) and attenuated meth-induced da elevation. |
2020-06-29 |
2023-08-13 |
Not clear |
| Matthew D Puhl, Rajeev I Desai, Shunsuke Takagi, Kendall T Presti, Michelle R Doyle, Rachel J Donahue, Samantha M Landino, Jack Bergman, William A Carlezon, Joseph T Coyl. N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse. Addiction biology. vol 24. issue 1. 2020-04-02. PMID:29168271. |
while basal dopamine (da) and glutamate release were elevated in the nucleus accumbens of sr-/- mice, cocaine-induced increases in da and glutamate release were blunted. |
2020-04-02 |
2023-08-13 |
mouse |
| Yuanmo Wang, Devesh Mishra, Jenny Bergman, Jacqueline D Keighron, Karolina P Skibicka, Ann-Sofie Can. Ultrafast Glutamate Biosensor Recordings in Brain Slices Reveal Complex Single Exocytosis Transients. ACS chemical neuroscience. vol 10. issue 3. 2020-03-31. PMID:30605606. |
here we show an amperometric, novel, ultrafast enzyme-based nanoparticle modified sensor, measuring random bursts of hundreds to thousands of rapid spontaneous glutamate exocytotic release events at approximately 30 hz frequency in the nucleus accumbens of rodent brain slices. |
2020-03-31 |
2023-08-13 |
Not clear |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
withdrawal from cocaine regulates expression of distinct glutamate re-uptake transporters in the nucleus accumbens (nac). |
2019-11-20 |
2023-08-13 |
rat |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
the present report tested the hypothesis that daily injections of cocaine would enhance d1 receptor responsiveness by infusing the d1 receptor agonist skf 38393 into the mpfc and monitoring glutamate and/or gaba release in the mpfc, nucleus accumbens and vta of saline- and cocaine-pretreated animals using in vivo microdialysis. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
intra-mpfc skf 38393 did not alter glutamate levels in the nucleus accumbens or vta of control animals. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
infusion of skf 38393 into the mpfc of animals previously exposed to cocaine increased and reduced glutamate release in the nucleus accumbens after 7 and 30 days of withdrawal, respectively and increased glutamate levels in the vta 7 and 30 days after daily cocaine injections. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeremy S Lum, Samuel J Millard, Xu-Feng Huang, Lezanne Ooi, Kelly A Newel. A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia. Journal of psychiatry & neuroscience : JPN. vol 43. issue 2. 2019-10-30. PMID:29481317. |
a postmortem analysis of nmda ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia. |
2019-10-30 |
2023-08-13 |
Not clear |
| Xia Li, Xiao-Qing Peng, Chloe J Jordan, Jie Li, Guo-Hua Bi, Yi He, Hong-Ju Yang, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29487381. |
mglur5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a cb1 receptor mechanism. |
2019-09-23 |
2023-08-13 |
Not clear |
| Chunxiao Qi, Xiaoming Ji, Guoliang Zhang, Yunxiao Kang, Yuanxiang Huang, Rui Cui, Shuangcheng Li, Huixian Cui, Geming Sh. Haloperidol ameliorates androgen-induced behavioral deficits in developing male rats. The Journal of endocrinology. vol 237. issue 2. 2019-08-27. PMID:29563235. |
the tp treatment produced the hyperactive motor behavior and grooming behavior as well as the increased levels of dopamine, tyrosine hydroxylase and dopamine transporter in the mesodopaminergic system and the elevated levels of serotonin in the nucleus accumbens, without affecting the levels of glutamate, γ-aminobutyric acid, norepinephrine and histamine in the caudate putamen and nucleus accumbens of pnd21 and pnd49 rats. |
2019-08-27 |
2023-08-13 |
rat |
| Natasha L Mason, Eef L Theunissen, Nadia R P W Hutten, Desmond H Y Tse, Stefan W Toennes, Peter Stiers, Johannes G Ramaeker. Cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 2. 2019-07-30. PMID:30553697. |
administration of thc increased striatal glutamate concentrations, and dopamine as indicated by a reduction in functional connectivity (fc) between the nucleus accumbens (nac) and cortical areas. |
2019-07-30 |
2023-08-13 |
Not clear |
| B M Siemsen, G Giannotti, J A McFaddin, M D Scofield, Jacqueline F McGint. Biphasic effect of abstinence duration following cocaine self-administration on spine morphology and plasticity-related proteins in prelimbic cortical neurons projecting to the nucleus accumbens core. Brain structure & function. vol 224. issue 2. 2019-07-01. PMID:30498893. |
cocaine self-administration (sa) in rats dysregulates glutamatergic signaling in the prelimbic (prl) cortex and glutamate release in the nucleus accumbens (na) core, promoting cocaine seeking. |
2019-07-01 |
2023-08-13 |
rat |
| Jinxu Liu, Pauravi J Gandhi, Ratnamala Pavuluri, Gajanan P Shelkar, Shashank M Dravi. Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens. Translational psychiatry. vol 8. issue 1. 2019-04-01. PMID:30315226. |
glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens. |
2019-04-01 |
2023-08-13 |
mouse |
| Yusuf Hussain, Sairam Krishnamurth. Piracetam attenuates binge eating disorder related symptoms in rats. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29654794. |
increased levels of plasma corticosterone (cort), glutamate in nucleus accumbens (nac), hypothalamus (hyp) and prefrontal cortex (pfc) indicate stress and excitotoxicity. |
2019-03-15 |
2023-08-13 |
rat |
| Marian T Sepulveda-Orengo, Kati L Healey, Ronald Kim, Alyson C Auriemma, Jennifer Rojas, Nicholas Woronoff, Rachel Hyppolite, Kathryn J Reissne. Riluzole Impairs Cocaine Reinstatement and Restores Adaptations in Intrinsic Excitability and GLT-1 Expression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 6. 2019-03-04. PMID:28990593. |
riluzole also reversed the cocaine-induced suppression of the high-affinity glutamate transporter 1 (eaat2/glt-1) in the nucleus accumbens (nac). |
2019-03-04 |
2023-08-13 |
rat |