| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silas A Buck, Mary M Torregrossa, Ryan W Logan, Zachary Freyber. Roles of dopamine and glutamate co-release in the nucleus accumbens in mediating the actions of drugs of abuse. The FEBS journal. vol 288. issue 5. 2021-07-20. PMID:32702182. |
roles of dopamine and glutamate co-release in the nucleus accumbens in mediating the actions of drugs of abuse. |
2021-07-20 |
2023-08-13 |
Not clear |
| Silas A Buck, Mary M Torregrossa, Ryan W Logan, Zachary Freyber. Roles of dopamine and glutamate co-release in the nucleus accumbens in mediating the actions of drugs of abuse. The FEBS journal. vol 288. issue 5. 2021-07-20. PMID:32702182. |
nevertheless, an important clue may relate to glutamate's ability to potentiate loading of da into synaptic vesicles within terminals in the nucleus accumbens in response to drug-induced elevations in neuronal activity, enabling a more robust release of da after stimulation. |
2021-07-20 |
2023-08-13 |
Not clear |
| Andre U Deutschmann, Julia M Kirkland, Lisa A Brian. Adolescent social isolation induced alterations in nucleus accumbens glutamate signalling. Addiction biology. 2021-07-19. PMID:34278652. |
adolescent social isolation induced alterations in nucleus accumbens glutamate signalling. |
2021-07-19 |
2023-08-13 |
mouse |
| Bethania Mongi-Bragato, María Paula Avalos, Andrea S Guzmán, Constanza García-Keller, Flavia A Bollati, Liliana M Cancel. Endogenous enkephalin is necessary for cocaine-induced alteration in glutamate transmission within the nucleus accumbens. The European journal of neuroscience. vol 53. issue 5. 2021-06-28. PMID:33159343. |
endogenous enkephalin is necessary for cocaine-induced alteration in glutamate transmission within the nucleus accumbens. |
2021-06-28 |
2023-08-13 |
mouse |
| Bethania Mongi-Bragato, María Paula Avalos, Andrea S Guzmán, Constanza García-Keller, Flavia A Bollati, Liliana M Cancel. Endogenous enkephalin is necessary for cocaine-induced alteration in glutamate transmission within the nucleus accumbens. The European journal of neuroscience. vol 53. issue 5. 2021-06-28. PMID:33159343. |
altered glutamate transmission within the nucleus accumbens (nac) has been proposed as a central mechanism underlying behavioural sensitisation associated with repeated cocaine exposure. |
2021-06-28 |
2023-08-13 |
mouse |
| Lan-Yuan Zhang, Yue-Qing Zhou, Zhi-Peng Yu, Xiao-Qin Zhang, Jie Shi, Hao-Wei She. Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 5. 2021-06-23. PMID:33514875. |
restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats. |
2021-06-23 |
2023-08-13 |
rat |
| Lucia Caffino, Michel M M Verheij, Karine Roversi, Giorgia Targa, Francesca Mottarlini, Piotr Popik, Agnieska Nikiforuk, Joanna Golebiowska, Fabio Fumagalli, Judith R Homber. Hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: Glutamate in the nucleus accumbens. British journal of pharmacology. vol 177. issue 19. 2021-06-21. PMID:32721055. |
hypersensitivity to amphetamine's psychomotor and reinforcing effects in serotonin transporter knockout rats: glutamate in the nucleus accumbens. |
2021-06-21 |
2023-08-13 |
rat |
| Gang Lei, Fei Liu, Peng Liu, Tong Jiao, Liu Yang, Zheng Chu, Li-Sha Deng, Yan Li, Yong-Hui Dan. Does genetic mouse model of constitutive Hint1 deficiency exhibit schizophrenia-like behaviors? Schizophrenia research. vol 222. 2021-06-17. PMID:32439293. |
total glutamate was decreased in the medial prefrontal cortex, nucleus accumbens (nac), and hip of ko mice. |
2021-06-17 |
2023-08-13 |
mouse |
| Zahra Ebrahimi, Nazanin Kahvandi, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab, Abdolrahman Sarih. The role of mGlu4 receptors within the nucleus accumbens in acquisition and expression of morphine-induced conditioned place preference in male rats. BMC neuroscience. vol 22. issue 1. 2021-06-17. PMID:33743609. |
several studies have shown that glutamate neurotransmission in the nucleus accumbens (nac) is required for the development of morphine-induced conditional place preference (cpp). |
2021-06-17 |
2023-08-13 |
rat |
| Lucia Caffino, Francesca Mottarlini, Giorgia Targa, Michel M M Verheij, Judith Homberg, Fabio Fumagall. Long access to cocaine self-administration dysregulates the glutamate synapse in the nucleus accumbens core of serotonin transporter knockout rats. British journal of pharmacology. 2021-05-21. PMID:33880773. |
it is well established that the nucleus accumbens and glutamate play a critical role in the motivation to take drugs of abuse. |
2021-05-21 |
2023-08-13 |
rat |
| Alaa M Hammad, Ghadeer M S Swiss, F Scott Hall, Suhair Hikmat, Youssef Sari, T M Al-Qirim, H A Amaw. Ceftriaxone Reduces Waterpipe Tobacco Smoke Withdrawal-induced Anxiety in rats via Modulating the Expression of TNF-α/NFĸB, Nrf2, and GLT-1. Neuroscience. vol 463. 2021-05-19. PMID:33836247. |
we examined the effects of waterpipe tobacco smoke (wts) on inflammatory mediators and astroglial glutamate transporters in mesocorticolimbic brain regions including the prefrontal cortex (pfc), nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-05-19 |
2023-08-13 |
rat |
| Anna K Radke, Elizabeth A Sneddon, Raizel M Frasier, Frederic W Hop. Recent Perspectives on Sex Differences in Compulsion-Like and Binge Alcohol Drinking. International journal of molecular sciences. vol 22. issue 7. 2021-05-12. PMID:33917517. |
we also describe studies regarding mechanisms that may underlie sex differences in maladaptive alcohol drinking, with some focus on the importance of nucleus accumbens (nacb) core and shell regions, several receptor types (dopamine, orexin, ampa-type glutamate), and possible contributions of sex hormones. |
2021-05-12 |
2023-08-13 |
Not clear |
| Andrea Stojakovic, Syed Muzzammil Ahmad, Kabirullah Lutf. Alterations of Amphetamine Reward by Prior Nicotine and Alcohol Treatment: The Role of Age and Dopamine. Brain sciences. vol 11. issue 4. 2021-04-28. PMID:33810331. |
mice were then immediately euthanized, their brain removed, and nucleus accumbens isolated and processed for the level of dopamine receptors and transporter and glutamate receptors. |
2021-04-28 |
2023-08-13 |
mouse |
| Lihua Yang, Ningning Guo, Wei Fan, Chunmin Ni, Mengbing Huang, Liping Bai, Le Zhang, Xianwen Zhang, Yunbo Wen, Ye Li, Xiaoshuang Zhou, Jie Ba. Thioredoxin-1 blocks methamphetamine-induced injury in brain through inhibiting endoplasmic reticulum and mitochondria-mediated apoptosis in mice. Neurotoxicology. vol 78. 2021-04-21. PMID:32203791. |
then we detected and found that meth increased the expression of n-methyl-d-asparate (nmda) receptor subunit 2b (nr2b) and the level of glutamate (glu) in the ventral tegmental area (vta) and nucleus accumbens (nac), while trx-1 overexpression suppressed the increases. |
2021-04-21 |
2023-08-13 |
mouse |
| Fawaz Alasmari, Hasan Alhaddad, Woonyen Wong, Richard L Bell, Youssef Sar. Ampicillin/Sulbactam Treatment Modulates NMDA Receptor NR2B Subunit and Attenuates Neuroinflammation and Alcohol Intake in Male High Alcohol Drinking Rats. Biomolecules. vol 10. issue 7. 2021-04-12. PMID:32664441. |
beta (β)-lactam antibiotics attenuate ethanol drinking through upregulation of astroglial glutamate transporters, especially glutamate transporter-1 (glt-1), in the mesocorticolimbic brain regions, including the nucleus accumbens (acb). |
2021-04-12 |
2023-08-13 |
rat |
| Simeon O A Helgers, Svilen Angelov, Marc A N Muschler, Alexander Glahn, Shadi Al-Afif, Yazeed Al Krinawe, Elvis J Hermann, Joachim K Krauss, Helge Frieling, Kerstin Schwabe, Mathias Rhei. Epigenetic Regulation of Neural Transmission after Cerebellar Fastigial Nucleus Lesions in Juvenile Rats. Cerebellum (London, England). 2021-04-09. PMID:33834423. |
lesioning of the fastigial nucleus led to significant differences in the epigenetic regulation of glutamate decarboxylase 1 and the oxytocin receptor in the nucleus accumbens and the prefrontal cortex. |
2021-04-09 |
2023-08-13 |
rat |
| Lailun Nahar, Caleb A Grant, Cameron Hewett, Diego Cortes, Ashlie N Reker, Seungwoo Kang, Doo-Sup Choi, Hyung W Na. Regulation of Pv-specific interneurons in the medial prefrontal cortex and reward-seeking behaviors. Journal of neurochemistry. vol 156. issue 2. 2021-04-08. PMID:32594517. |
interestingly, our microdialysis results demonstrate that alcohol exposure inhibits pv-fsi functioning in the medial prefrontal cortex (mpfc) and this consequently can regulate glutamate levels downstream in the nucleus accumbens. |
2021-04-08 |
2023-08-13 |
mouse |
| Ju Hwan Yang, Sumin Sohn, Sunghyun Kim, Jieun Kim, Jeong Hwan Oh, In Soo Ryu, Bok Soon Go, Eun Sang Cho. Repeated nicotine exposure increases the intracellular interaction between ERK-mGluR5 in the nucleus accumbens more in adult than adolescent rats. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32339332. |
we investigated the difference in the degree of interaction between extracellular signal-regulated kinase (erk) and metabotropic glutamate receptor subtype 5 (mglur5) in the nucleus accumbens (nac) after repeated exposure to nicotine in adult and adolescent rats. |
2021-03-25 |
2023-08-13 |
rat |
| Allison R Bechard, Carly N Logan, Javier Mesa, Yasmin Padovan-Hernandez, Harrison Blount, Virginia L Hodges, Lori A Knacksted. Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cue-induced cocaine seeking. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32558119. |
ceftriaxone is an antibiotic that reliably attenuates the reinstatement of cocaine seeking after extinction while preventing the nucleus accumbens (na) core glutamate efflux that drives reinstatement. |
2021-03-25 |
2023-08-13 |
rat |
| Rodrigo Iván Osnaya-Ramírez, Madahi Palma-Gómez, Carolina Escoba. Binge eating for sucrose is time of day dependent and independent of food restriction: Effects on mesolimbic structures. Behavioral neuroscience. vol 134. issue 3. 2021-02-01. PMID:32150421. |
this study explored in rats the differential contribution of restricted food access to chow and sucrose for developing beb, it explored whether beb exhibits a day-night pattern, and whether behavioral changes are associated with the number of tyrosine hydroxylase (th) positive cells in the ventral tegmental area, with the expression of dopamine 1 receptors (d1) and glutamate receptor subunit 1 receptors (glur1) in the nucleus accumbens. |
2021-02-01 |
2023-08-13 |
rat |