| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V I Kuznetsov, O V Godukhi. Mechanism of methionine-enkephalin modulation of glutamatergic transmission in the rat striatum. Neuroscience letters. vol 57. issue 2. 1985-10-07. PMID:2863790. |
analysis of binding curves suggests that the reduced [3h]glutamate binding in the rat striatum membranes was due to decreased binding sites, whereas binding affinity was not changed. |
1985-10-07 |
2023-08-11 |
rat |
| M Docherty, H F Bradford, J Y Wu, T H Joh, D J Rei. Evidence for specific immunolysis of nerve terminals using antisera against choline acetyltransferase, glutamate decarboxylase and tyrosine hydroxylase. Brain research. vol 339. issue 1. 1985-10-01. PMID:2862953. |
synaptosomes prepared from striatum or cerebral cortex of rat brain were incubated with antibodies raised against three neurotransmitter biosynthetic enzymes, choline acetyltransferase, glutamate decarboxylase and tyrosine hydroxylase in the presence or absence of complement. |
1985-10-01 |
2023-08-11 |
rat |
| M Docherty, H F Bradford, J Y Wu, T H Joh, D J Rei. Evidence for specific immunolysis of nerve terminals using antisera against choline acetyltransferase, glutamate decarboxylase and tyrosine hydroxylase. Brain research. vol 339. issue 1. 1985-10-01. PMID:2862953. |
in both striatum and cortex, antibodies to choline acetyltransferase lysed only cholinergic while those against glutamate decarboxylase only lysed gabaergic nerve terminals. |
1985-10-01 |
2023-08-11 |
rat |
| J M Murphy, S D Cunningham, W J McBrid. Effects of 250 mg% ethanol on monoamine and amino acid release from rat striatal slices. Brain research bulletin. vol 14. issue 5. 1985-09-27. PMID:2862965. |
the in vitro findings have led to the hypothesis that the elevated dopac and hva levels observed in the striatum following an acute ip injection of 2.5 g/kg of ethanol are due to increased release of da produced by the excitatory actions of glutamate (and/or aspartate) on dopaminergic neurons. |
1985-09-27 |
2023-08-11 |
rat |
| J K Disbrow, J A Rut. Differential glutamate release in brain regions of long sleep and short sleep mice. Alcohol (Fayetteville, N.Y.). vol 1. issue 3. 1985-08-30. PMID:6152600. |
the 30 mm k+-induced release of endogenous glutamate has been examined in slices of cortex, hippocampus, striatum and cerebellum from "short sleep" and "long sleep" mice, lines genetically selected for differential response to acute ethanol administration. |
1985-08-30 |
2023-08-12 |
mouse |
| J K Disbrow, J A Rut. Differential glutamate release in brain regions of long sleep and short sleep mice. Alcohol (Fayetteville, N.Y.). vol 1. issue 3. 1985-08-30. PMID:6152600. |
in cortex and striatum, glutamate release was significantly higher in "short sleep" mice, while in hippocampus the difference was reversed. |
1985-08-30 |
2023-08-12 |
mouse |
| A G Chapman, S C Cheetham, G P Hart, B S Meldrum, E Westerber. Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents. Journal of neurochemistry. vol 45. issue 2. 1985-08-20. PMID:2861248. |
glutamate levels fell in cortex after beta-ccm and in striatum after dmcm. |
1985-08-20 |
2023-08-11 |
mouse |
| R S Flint, J M Murphy, W J McBrid. Release of endogenous dopamine, 3,4-dihydroxyphenylacetic acid, and amino acid transmitters from rat striatal slices. Neurochemical research. vol 10. issue 4. 1985-07-23. PMID:2860579. |
the release of endogenous dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac) was measured in superfused striatal slices of the rat and the results compared with data obtained for the release of endogenous (a) da and dopac in the cerebral cortex, nucleus accumbens and thalamus; (b) 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), gaba, and glutamate in the striatum; and (c) gaba, glutamate and 5-ht in the cerebral cortex. |
1985-07-23 |
2023-08-11 |
rat |
| R S Flint, J M Murphy, W J McBrid. Release of endogenous dopamine, 3,4-dihydroxyphenylacetic acid, and amino acid transmitters from rat striatal slices. Neurochemical research. vol 10. issue 4. 1985-07-23. PMID:2860579. |
on the other hand, in the striatum, 16 mm mg2+ inhibited the ca2+-dependent, 60 mm k+-stimulated release of gaba and glutamate. |
1985-07-23 |
2023-08-11 |
rat |
| S Lindgren, N E Andé. Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:3981161. |
the concentrations of gaba, glutamate, serine, glutamine, threonine, glycine and taurine in the substantia nigra and in the corpus striatum of the rat were determined electrochemically following condensation with o-phthalaldehyde-beta-mercaptoethanol and reverse-phase, high performance liquid chromatography. |
1985-05-03 |
2023-08-11 |
rat |
| R M Beckstead, K S Kerse. Immunohistochemical demonstration of differential substance P-, met-enkephalin-, and glutamic-acid-decarboxylase-containing cell body and axon distributions in the corpus striatum of the cat. The Journal of comparative neurology. vol 232. issue 4. 1985-04-26. PMID:2579980. |
the immunohistochemical localization of neuronal cell bodies and axons reactive for substance p (sp) and methionine-enkephalin (me) was investigated in the corpus striatum of the adult cat brain and compared with that of glutamate decarboxylase (gad), synthetic enzyme for gamma-aminobutyric acid. |
1985-04-26 |
2023-08-11 |
cat |
| S Kwak, I Kanazawa, H Sugita, Y Toyokur. Tridimensional distribution of markers of neurotransmitters within the "accumbens area" of normal human brains. Neuroscience. vol 13. issue 3. 1985-04-02. PMID:6098857. |
although the demarcation of the human nucleus accumbens inferred from choline acetyltransferase and glutamate decarboxylase distribution is not precise, it is clear that the accumbens area which corresponds to the animal nucleus accumbens is separated from the remainder of the striatum. |
1985-04-02 |
2023-08-12 |
human |
| C J Carte. Increased alanine aminotransferase activity in the Huntington's disease putamen. Journal of the neurological sciences. vol 66. issue 1. 1985-02-22. PMID:6151588. |
this increase was not observed in rats with kainic acid lesions of the striatum, and suggests a considerable alteration of glutamate and pyruvate metabolism as a feature of huntington's disease. |
1985-02-22 |
2023-08-12 |
rat |
| J M Durand-Gorde, J Bert, A Nieoullo. Early changes in tyrosine hydroxylase and glutamate decarboxylase activity in the golden hamster striatum after intracerebral inoculation of the nigrostriatal system with scrapie agent (strain 263 K). Neuroscience letters. vol 51. issue 1. 1985-02-15. PMID:6151152. |
early changes in tyrosine hydroxylase and glutamate decarboxylase activity in the golden hamster striatum after intracerebral inoculation of the nigrostriatal system with scrapie agent (strain 263 k). |
1985-02-15 |
2023-08-12 |
Not clear |
| H H Kornhuber, J Kornhuber, J S Kim, M E Kornhube. [A biochemical theory of schizophrenia]. Der Nervenarzt. vol 55. issue 11. 1985-02-04. PMID:6151120. |
the classical and the new atypical neuroleptic drugs show differential effects on glutamate and gaba in the brain tissue of the striatum and in the cerebrospinal fluid. |
1985-02-04 |
2023-08-12 |
Not clear |
| H H Kornhuber, J Kornhuber, J S Kim, M E Kornhube. [A biochemical theory of schizophrenia]. Der Nervenarzt. vol 55. issue 11. 1985-02-04. PMID:6151120. |
whereas sulpiride diminishes glutamate in the striatum and enhances glutamate in the cerebrospinal fluid, tiapride does not affect either of them. |
1985-02-04 |
2023-08-12 |
Not clear |
| G J McBean, P J Robert. Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. Journal of neurochemistry. vol 44. issue 1. 1985-01-23. PMID:2856883. |
injection of 170 nmol of the glutamate uptake inhibitor, dl-threo-3-hydroxyaspartate, into the intact striatum also causes neuronal degeneration, which is accompanied by a reduction in markers for cholinergic and gabaergic neurones. |
1985-01-23 |
2023-08-11 |
rat |
| M Sandberg, H K Ward, H F Bradfor. Effect of cortico-striate pathway lesion on the activities of enzymes involved in synthesis and metabolism of amino acid neurotransmitters in the striatum. Journal of neurochemistry. vol 44. issue 1. 1985-01-23. PMID:2856884. |
the content of glutamate and glutamine in the denervated striatum followed qualitatively the changes in glutaminase and gs. |
1985-01-23 |
2023-08-11 |
Not clear |
| H Notman, R Whitney, K Jhamanda. Kainic acid evoked release of D-[3H]aspartate from rat striatum in vitro: characterization and pharmacological modulation. Canadian journal of physiology and pharmacology. vol 62. issue 9. 1985-01-14. PMID:6498619. |
a presynaptic stimulatory action of kainic acid (ka) on the release of glutamate from corticostriatal neurons is thought to contribute to the toxic effect of ka on cell bodies of neurons in the striatum. |
1985-01-14 |
2023-08-12 |
rat |
| J F Giguère, R F Butterwort. Amino acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy. Neurochemical research. vol 9. issue 9. 1985-01-09. PMID:6150451. |
glutamate, on the other hand, was selectively increased in striatum and cerebellum, two regions of brain shown to exhibit early morphologically-characterised astrocytic abnormalities in rats with pca. |
1985-01-09 |
2023-08-12 |
rat |