| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Giguère, R F Butterwort. Amino acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy. Neurochemical research. vol 9. issue 9. 1985-01-09. PMID:6150451. |
onset of severe neurological dysfunction was accompanied by significantly decreased glutamine and glutamate in striatum and cerebellum. |
1985-01-09 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. |
1984-12-20 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
by contrast, we found in an earlier investigation with sulpiride, an atypical neuroleptic drug, a changed glutamate level in the striatum and the csf and an unaltered gaba level. |
1984-12-20 |
2023-08-12 |
rat |
| A Luini, O Goldberg, V I Teichber. Differential sensitivity of selected rat brain areas to excitatory neurotransmitters released by K+ depolarization. Neuroscience letters. vol 49. issue 3. 1984-11-26. PMID:6149499. |
the results indicate that the so-called n-methyl-d-aspartate receptor mediates the bulk of the excitatory transactions in the cortex and striatum whereas a subsynaptic glutamate receptor may mediate those in the hippocampus and cerebellum. |
1984-11-26 |
2023-08-12 |
rat |
| J T Greenamyre, A B Young, J B Penne. Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 8. 1984-09-28. PMID:6088729. |
however, quisqualate displacement of [3h]glutamate binding revealed two well-resolved sites with kis of 12 nm and 114 microm in striatum. |
1984-09-28 |
2023-08-12 |
rat |
| M Erecińska, D Nelson, D F Wilson, I A Silve. Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion. Brain research. vol 304. issue 1. 1984-09-12. PMID:6146383. |
the levels of amino acids in 6 regions of the brain (cortex, hippocampus, striatum, diencephalon, stem and cerebellum) were determined during an ischemic insult of 30 min and after recovery periods of up to 10 h. the results were analyzed in two groups: putative neurotransmitters (gaba, aspartate, glutamate, taurine, glycine and alanine) and non-neurotransmitters. |
1984-09-12 |
2023-08-12 |
rat |
| P J Roberts, G J McBean, N A Sharif, E M Thoma. Striatal glutamatergic function: modifications following specific lesions. Brain research. vol 235. issue 1. 1984-08-13. PMID:6145487. |
the effects of specific lesions of the striatum: (a) hemidecortication; (b) striatal injection of (+/-) ibotenate; and (c) 6-hydroxydopamine injections into the substantia nigra, were investigated on specific [3h]glutamate binding to striatal membranes. |
1984-08-13 |
2023-08-12 |
Not clear |
| P J Roberts, G J McBean, N A Sharif, E M Thoma. Striatal glutamatergic function: modifications following specific lesions. Brain research. vol 235. issue 1. 1984-08-13. PMID:6145487. |
ibotenate lesions which destroy target neurones for the glutamatergic fibres (sparing terminals), reduced glutamate binding in the striatum, as did nigral 6-ohda lesions which delete striatal dopaminergic terminals. |
1984-08-13 |
2023-08-12 |
Not clear |
| P J Roberts, G J McBean, N A Sharif, E M Thoma. Striatal glutamatergic function: modifications following specific lesions. Brain research. vol 235. issue 1. 1984-08-13. PMID:6145487. |
this finding supports the concept of there being glutamate receptors on pre-synaptic dopamine terminals in the striatum, involved in regulation of dopamine release. |
1984-08-13 |
2023-08-12 |
Not clear |
| E Keller, J T Cummins, K von Hunge. Regional effects of ethanol on glutamate levels, uptake and release in slice and synaptosome preparations from rat brain. Substance and alcohol actions/misuse. vol 4. issue 6. 1984-06-19. PMID:6144191. |
ethanol withdrawal increases k+-stimulated glutamate release in cortex and hippocampus and glutamate levels in cortex, striatum and hippocampus. |
1984-06-19 |
2023-08-12 |
rat |
| E Keller, J T Cummins, K von Hunge. Regional effects of ethanol on glutamate levels, uptake and release in slice and synaptosome preparations from rat brain. Substance and alcohol actions/misuse. vol 4. issue 6. 1984-06-19. PMID:6144191. |
combined level-release data suggest an effect of ethanol on glutamate distribution in cortex and striatum. |
1984-06-19 |
2023-08-12 |
rat |
| A Nieoullon, L Kerkerian, N Dusticie. Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum. Neuroscience letters. vol 43. issue 2-3. 1984-05-11. PMID:6143287. |
presynaptic dopaminergic control of high affinity glutamate uptake in the striatum. |
1984-05-11 |
2023-08-12 |
rat |
| A Nieoullon, L Kerkerian, N Dusticie. Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum. Neuroscience letters. vol 43. issue 2-3. 1984-05-11. PMID:6143287. |
results show that the stimulation of the corticostriatal neurons induces an activation of the uptake of glutamate (glu) in the striatum resulting from an increase in the affinity of the transport site for glu. |
1984-05-11 |
2023-08-12 |
rat |
| G J McBean, P J Robert. Chronic infusion of L-glutamate causes neurotoxicity in rat striatum. Brain research. vol 290. issue 2. 1984-03-22. PMID:6140988. |
chronic infusion of a high dose of monosodium glutamate (approximately 8 nmol/min) into the rat left striatum, over a period of 1 week, caused degeneration of striatal neurones. |
1984-03-22 |
2023-08-12 |
human |
| E Hansso. Accumulation of putative amino acid neurotransmitters, monoamines and D-Ala2-Met-enkephalinamide in primary astroglial cultures from various brain areas, visualized by autoradiography. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6140983. |
the most prominent accumulation of grains was seen after incubating astroglial cultures from cerebral cortex, hippocampus and striatum with glutamate. |
1984-03-12 |
2023-08-12 |
Not clear |
| M D Hall, P Jenner, E Kelly, C D Marsde. Differential anatomical location of [3H]-N,n-propylnorapomorphine and [3H]-spiperone binding sites in the striatum and substantia nigra of the rat. British journal of pharmacology. vol 79. issue 2. 1984-02-14. PMID:6418246. |
binding sites labelled by [3h]-spiperone in striatum were found to lie on striatal cell bodies and on the terminals of cortico-striate glutamate fibres, but not on presynaptic dopamine terminals. |
1984-02-14 |
2023-08-12 |
rat |
| O Giorgi, J L Mee. Gamma-aminobutyric acid turnover in rat striatum: effects of glutamate and kainic acid. Journal of neurochemistry. vol 42. issue 1. 1984-01-26. PMID:6139420. |
gamma-aminobutyric acid turnover in rat striatum: effects of glutamate and kainic acid. |
1984-01-26 |
2023-08-12 |
rat |
| E Westerberg, A G Chapman, B S Meldru. Effect of 2-amino-7-phosphonoheptanoic acid on regional brain amino acid levels in fed and fasted rodents. Journal of neurochemistry. vol 41. issue 6. 1984-01-07. PMID:6644309. |
in fasted rats and mice, 2-amino-7-phosphonoheptanoic acid significantly increased glutamine in rat cortex and mouse striatum, decreased glutamate content in rat striatum, and decreased aspartate concentration in all regions except mouse cortex and striatum. |
1984-01-07 |
2023-08-12 |
mouse |
| H Kaiya, K Takeuchi, H Yoshida, T Kondo, F Sanpei, Y Okada, M Namb. Effects of subchronic treatment of methamphetamine haloperidol on the rat brain levels of GABA, glutamate and aspartate. Folia psychiatrica et neurologica japonica. vol 37. issue 1. 1983-10-21. PMID:6136454. |
methamphetamine caused no statistically-significant changes in the gaba contents in any brain areas, a significant decrease in the glutamate content of the striatum, hippocampus and midbrain and an increase in the aspartate content of the hypothalamus. |
1983-10-21 |
2023-08-12 |
rat |
| H Kaiya, K Takeuchi, H Yoshida, T Kondo, F Sanpei, Y Okada, M Namb. Effects of subchronic treatment of methamphetamine haloperidol on the rat brain levels of GABA, glutamate and aspartate. Folia psychiatrica et neurologica japonica. vol 37. issue 1. 1983-10-21. PMID:6136454. |
haloperidol treatment resulted in no changes in the gaba content, a significant decrease in the glutamate content of the striatum and a significant increase in the aspartate content in the frontal cortex. |
1983-10-21 |
2023-08-12 |
rat |