| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G J Rowlands, P J Robert. Specific calcium-dependent release of endogenous glutamate from rat striatum is reduced by destruction of the cortico-striatal tract. Experimental brain research. vol 39. issue 2. 1980-10-21. PMID:7398819. |
specific calcium-dependent release of endogenous glutamate from rat striatum is reduced by destruction of the cortico-striatal tract. |
1980-10-21 |
2023-08-12 |
rat |
| S R Vincent, E G McGee. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. Brain research. vol 184. issue 1. 1980-05-14. PMID:6244054. |
a comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. |
1980-05-14 |
2023-08-12 |
rat |
| S R Vincent, E G McGee. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. Brain research. vol 184. issue 1. 1980-05-14. PMID:6244054. |
the specific sodium-dependent binding of [3h]glutamate to membranes of the rat striatum was examined and a comparison made with high affinity glutamate uptake. |
1980-05-14 |
2023-08-12 |
rat |
| S R Vincent, E G McGee. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. Brain research. vol 184. issue 1. 1980-05-14. PMID:6244054. |
removal of the cortical afferents to the striatum resulted in a parallel decrease in na+-dependent glutamate binding and in high-affinity glutamate uptake. |
1980-05-14 |
2023-08-12 |
rat |
| S R Vincent, E G McGee. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. Brain research. vol 184. issue 1. 1980-05-14. PMID:6244054. |
after the injection of the neurotoxin kainic acid into the striatum, the density of na+-dependent glutamate binding sites was reduced by 40%, while high-affinity uptake showed no significant decrease. |
1980-05-14 |
2023-08-12 |
rat |
| S R Vincent, E G McGee. A comparison of sodium-dependent glutamate binding with high-affinity glutamate uptake in rat striatum. Brain research. vol 184. issue 1. 1980-05-14. PMID:6244054. |
the results suggest that about half the na+-dependent glutamate binding sites in the striatum represent high-affinity uptake sites on the corticostriatal terminals. |
1980-05-14 |
2023-08-12 |
rat |
| K Biziere, H Thompson, J T Coyl. Characterization of specific, high-affinity binding sites for L-[3H]glutamic acid in rat brain membranes. Brain research. vol 183. issue 2. 1980-04-17. PMID:7353147. |
prior kainate lesion of the neurons intrinsic to the striatum results in a 45% decrement in specific binding of l-[3h]glutamic acid whereas cortical ablation, which causes degeneration of a cortical-striatal glutamatergic projection and reduces striatal glutamate synaptosomal uptake, does not affect specific binding. |
1980-04-17 |
2023-08-12 |
rat |
| W J Nicklas, R C Duvoisin, S Ber. Amino acids in rat neostriatum: alteration by kainic acid lesion. Brain research. vol 167. issue 1. 1979-09-17. PMID:455057. |
unilateral stereotaxic injection of 10 nmol of the glutamomimetic substance, kainic acid, into the rat striatum caused permanent, significant decreases in the levels of glutamate (40--50%), aspartate (35--40%), taurine (20--30%) and gaba (60--70%). |
1979-09-17 |
2023-08-11 |
rat |
| P J Roberts, S D Anderso. Stimulatory effect of L-glutamate and related amino acids on [3H]dopamine release from rat striatum: an in vitro model for glutamate actions. Journal of neurochemistry. vol 32. issue 5. 1979-07-25. PMID:438822. |
stimulatory effect of l-glutamate and related amino acids on [3h]dopamine release from rat striatum: an in vitro model for glutamate actions. |
1979-07-25 |
2023-08-11 |
rat |
| T Hattori, E G McGeer, P L McGee. Fine structural analysis of the cortico-striatal pathway. The Journal of comparative neurology. vol 185. issue 2. 1979-06-11. PMID:34635. |
lesions of the tract result in reductions in the striatum of glutamate levels as well as high affinity uptake of glutamate into synaptosomes. |
1979-06-11 |
2023-08-11 |
rat |
| T Hattori, E G McGeer, P L McGee. Fine structural analysis of the cortico-striatal pathway. The Journal of comparative neurology. vol 185. issue 2. 1979-06-11. PMID:34635. |
furthermore, such lesions eliminate the neurotoxicity of the glutamate analog kainic acid when injected into the striatum. |
1979-06-11 |
2023-08-11 |
rat |
| J T Coyle, M E Molliver, M J Kuha. In situ injection of kainic acid: a new method for selectively lesioning neural cell bodies while sparing axons of passage. The Journal of comparative neurology. vol 180. issue 2. 1978-08-14. PMID:659663. |
the morphologic sequelae following stereotaxic injection into the rat striatum of kainic acid, a conformationally restricted analogue of glutamate, were examined by means of bright field, histofluorescence and electron microscopic techniques. |
1978-08-14 |
2023-08-11 |
rat |
| N M Friedle, P H Kelly, K E Moor. Regional brain atrophy and reductions in glutamate release and uptake after intrastriatal kainic acid. British journal of pharmacology. vol 63. issue 1. 1978-07-15. PMID:148306. |
5 the high affinity glutamate uptake into a crude synaptosomal preparation of the striatum was reduced by 64% 5 days after kainic acid and still reduced by 67% at 10 weeks. |
1978-07-15 |
2023-08-11 |
rat |
| N M Friedle, P H Kelly, K E Moor. Regional brain atrophy and reductions in glutamate release and uptake after intrastriatal kainic acid. British journal of pharmacology. vol 63. issue 1. 1978-07-15. PMID:148306. |
6 the efflux of glutamate from slices of the striatum in the presence of 52 mm k+ was reduced by approximately 75% 5 days and 15 weeks after kainic acid. |
1978-07-15 |
2023-08-11 |
rat |
| N M Friedle, P H Kelly, K E Moor. Regional brain atrophy and reductions in glutamate release and uptake after intrastriatal kainic acid. British journal of pharmacology. vol 63. issue 1. 1978-07-15. PMID:148306. |
7 in vitro kainic acid (10(-4) m) neither altered the high affinity uptake of radiolabelled glutamate into a homogenate of the striatum, nor released endogenous glutamate from slices of striatum. |
1978-07-15 |
2023-08-11 |
rat |
| P Campochiaro, J T Coyl. Ontogenetic development of kainate neurotoxicity: correlates with glutamatergic innervation. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 4. 1978-06-17. PMID:25442. |
the maturational increase in striatal neuronal sensitivity to kainate correlates with the development of glutamatergic innervation to the striatum, as measured by [3h]glutamate uptake by synaptosomes, and with the development of a postsynaptic, high-affinity receptor site for kainate. |
1978-06-17 |
2023-08-11 |
rat |
| P Campochiaro, R Schwarcz, J T Coyl. GABA receptor binding in rat striatum: localization and effects of denervation. Brain research. vol 136. issue 3. 1978-01-27. PMID:922498. |
intrastriatal injection of 2 microgram of kainic acid, a conformationally restricted analogue of glutamate, causes degeneration of gabaergic neurons intrinsic to the striatum while sparing axons of extrinsic neurons terminating in or passing through the region. |
1978-01-27 |
2023-08-11 |
rat |
| R Schwarcz, J T Coyl. Striatal lesions with kainic acid: neurochemical characteristics. Brain research. vol 127. issue 2. 1977-07-18. PMID:16686. |
stereotaxic injection of 2.5 microng of kainic acid, a rigid analogue of glutamate into the rat striatum caused a 70% reduction in the striatum of the cholinergic parameters, choline acetyltransferase, acetylcholine and synaptosomal uptake of choline and a similar reduction in the gabaergic parameters, glutamic acid decarboxylase, psi-aminobutyric acid (gaba) and synaptosomal uptake of gaba. |
1977-07-18 |
2023-08-11 |
rat |