| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Zambrano, P M Martínez-Samayoa, C J Bautista, M Deás, L Guillén, G L Rodríguez-González, C Guzmán, F Larrea, P W Nathaniels. Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation. The Journal of physiology. vol 566. issue Pt 1. 2005-09-16. PMID:15860532. |
we conclude that maternal protein restriction adversely affects glucose and insulin metabolism of male and female f2 offspring in a manner specific to sex and developmental time window during their mother's (the f1) fetal and neonatal development. |
2005-09-16 |
2023-08-12 |
rat |
| Katrine Almind, C Ronald Kah. Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes. vol 53. issue 12. 2005-04-14. PMID:15561960. |
over an 18-week period, b6 and f2 mice gained more weight, had higher levels of insulin and leptin, and showed greater glucose intolerance than 129 mice, despite lower food intake. |
2005-04-14 |
2023-08-12 |
mouse |
| Chieko Tsukahara, Fumihiro Sugiyama, Beverly Paigen, Satoshi Kunita, Ken-Ichi Yagam. Blood pressure in 15 inbred mouse strains and its lack of relation with obesity and insulin resistance in the progeny of an NZO/HILtJ x C3H/HeJ intercross. Mammalian genome : official journal of the International Mammalian Genome Society. vol 15. issue 12. 2005-03-24. PMID:15599552. |
to understand the relationship of blood pressure with insulin resistance and obesity, we produced f1 and f2 progeny from reciprocal crosses of nzo, the strain with obesity, diabetes, and high blood pressure, and the strain with the lowest blood pressures, c3h/hej. |
2005-03-24 |
2023-08-12 |
mouse |
| Chieko Tsukahara, Fumihiro Sugiyama, Beverly Paigen, Satoshi Kunita, Ken-Ichi Yagam. Blood pressure in 15 inbred mouse strains and its lack of relation with obesity and insulin resistance in the progeny of an NZO/HILtJ x C3H/HeJ intercross. Mammalian genome : official journal of the International Mammalian Genome Society. vol 15. issue 12. 2005-03-24. PMID:15599552. |
the body mass index (bmi) and plasma insulin levels of f2 progeny correlated significantly and positively with plasma leptin levels, suggesting that obesity is associated with insulin resistance. |
2005-03-24 |
2023-08-12 |
mouse |
| Daniel C Benyshek, Carol S Johnston, John F Marti. Post-natal diet determines insulin resistance in fetally malnourished, low birthweight rats (F1) but diet does not modify the insulin resistance of their offspring (F2). Life sciences. vol 74. issue 24. 2004-04-20. PMID:15051426. |
post-natal diet determines insulin resistance in fetally malnourished, low birthweight rats (f1) but diet does not modify the insulin resistance of their offspring (f2). |
2004-04-20 |
2023-08-12 |
rat |
| Daniel C Benyshek, Carol S Johnston, John F Marti. Post-natal diet determines insulin resistance in fetally malnourished, low birthweight rats (F1) but diet does not modify the insulin resistance of their offspring (F2). Life sciences. vol 74. issue 24. 2004-04-20. PMID:15051426. |
we examined the effects of prenatal and postnatal nutrition on birthweight and insulin sensitivity, indicated by the glucose/insulin (g/i) ratio, in adult rats (f1 generation) and in their adult offspring (f2 generation). |
2004-04-20 |
2023-08-12 |
rat |
| Daniel C Benyshek, Carol S Johnston, John F Marti. Post-natal diet determines insulin resistance in fetally malnourished, low birthweight rats (F1) but diet does not modify the insulin resistance of their offspring (F2). Life sciences. vol 74. issue 24. 2004-04-20. PMID:15051426. |
insulin sensitivity was significantly reduced in all f2 animals versus control animals, regardless of dietary treatment. |
2004-04-20 |
2023-08-12 |
rat |
| Katrine Almind, Rohit N Kulkarni, Scott M Lannon, C Ronald Kah. Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance. Diabetes. vol 52. issue 6. 2003-07-18. PMID:12765967. |
f2 male mice created by an intercross between these two strains exhibit a 60% incidence of diabetes and a bell-shaped distribution of insulin levels as related to glucose, reminiscent of that in humans with type 2 diabetes. |
2003-07-18 |
2023-08-12 |
mouse |
| Rea Victoria P Anunciado, Masahiko Nishimura, Masayuki Mori, Akira Ishikawa, Shin Tanaka, Fumihiko Horio, Tamio Ohno, Takao Namikaw. Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice. Experimental animals. vol 52. issue 1. 2003-05-07. PMID:12638235. |
quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (sm/j x a/j)f2 mice. |
2003-05-07 |
2023-08-12 |
mouse |
| Rea Victoria P Anunciado, Masahiko Nishimura, Masayuki Mori, Akira Ishikawa, Shin Tanaka, Fumihiko Horio, Tamio Ohno, Takao Namikaw. Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice. Experimental animals. vol 52. issue 1. 2003-05-07. PMID:12638235. |
quantitative trait locus (qtl) analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels at 10 weeks of age was performed in 321 f2 offspring from sm/j and a/j mice. |
2003-05-07 |
2023-08-12 |
mouse |
| P Razdan, A M Mwanza, H Kindahl, F Hultén, S Einarsso. Impact of postovulatory food deprivation on the ova transport, hormonal profiles and metabolic changes in sows. Acta veterinaria Scandinavica. vol 42. issue 1. 2002-01-03. PMID:11455901. |
blood samples were collected every second hour from about 12 h before expected ovulation in the second oestrus after weaning until slaughter and were analysed for progesterone, prostaglandin f2 alpha-metabolite, insulin, glucose, free fatty acids and triglycerides. |
2002-01-03 |
2023-08-12 |
Not clear |
| M H Toyama, E M Carneiro, S Marangoni, R L Barbosa, G Corso, A C Boscher. Biochemical characterization of two crotamine isoforms isolated by a single step RP-HPLC from Crotalus durissus terrificus (South American rattlesnake) venom and their action on insulin secretion by pancreatic islets. Biochimica et biophysica acta. vol 1474. issue 1. 2000-05-04. PMID:10699490. |
in the presence of 16.7 mmol glucose/l, f2 (5 microg/ml), but not f3, increased insulin secretion two-fold, whereas native crotamine (1.5, 5 and 16.5 microg/ml) potentiated the secretion dose-dependently. |
2000-05-04 |
2023-08-12 |
mouse |
| M H Toyama, E M Carneiro, S Marangoni, R L Barbosa, G Corso, A C Boscher. Biochemical characterization of two crotamine isoforms isolated by a single step RP-HPLC from Crotalus durissus terrificus (South American rattlesnake) venom and their action on insulin secretion by pancreatic islets. Biochimica et biophysica acta. vol 1474. issue 1. 2000-05-04. PMID:10699490. |
the increase in insulin secretion induced by f2 fraction (5 microg/ml) was similar to that obtained with 16.5 microg of native crotamine/ml. |
2000-05-04 |
2023-08-12 |
mouse |
| J F Martin, C S Johnston, C T Han, D C Benyshe. Nutritional origins of insulin resistance: a rat model for diabetes-prone human populations. The Journal of nutrition. vol 130. issue 4. 2000-04-24. PMID:10736323. |
however, their offspring (f2 generation) displayed a markedly elevated insulin response [+80% at 30 min (p < 0.05) and + 230% at 120 min (p < 0.001) postglucose challenge]. |
2000-04-24 |
2023-08-12 |
human |
| J F Martin, C S Johnston, C T Han, D C Benyshe. Nutritional origins of insulin resistance: a rat model for diabetes-prone human populations. The Journal of nutrition. vol 130. issue 4. 2000-04-24. PMID:10736323. |
the insulin response of the f2 generation rats fed the high-energy, hf diet was even more pronounced [+130% at 30 min (p < 0.003) and + 250% at 120 min (p < 0.001) postglucose challenge]. |
2000-04-24 |
2023-08-12 |
human |
| J Suto, S Matsuura, K Imamura, H Yamanaka, K Sekikaw. Genetic analysis of non-insulin-dependent diabetes mellitus in KK and KK-Ay mice. European journal of endocrinology. vol 139. issue 6. 1999-02-04. PMID:9916873. |
in f2 a/a progenies, we identified a qtl for fasting glucose levels on chromosome 6 (lod score 6.0) and three loci with suggestive linkage on chromosomes 3, 5 and 14, but could not identify loci accounting for glucose tolerance and plasma insulin levels. |
1999-02-04 |
2023-08-12 |
mouse |
| D H Moralejo, T Ogino, M Zhu, K Toide, S Wei, K Wei, T Yamada, A Mizuno, K Matsumoto, K Shim. Identification of a quantitative trait locus influencing plasma insulin levels after 70% pancreatectomy using the OLETF rat. The Journal of veterinary medical science. vol 60. issue 10. 1999-02-02. PMID:9819774. |
our investigation was designed to identify quantitative trait loci (qtls) responsible for beta-cell mass and plasma insulin levels after partial pancreatectomy by performing a genome-wide scan in an f2 intercross obtained by mating the oletf and the fischer-344 (f344) rats. |
1999-02-02 |
2023-08-12 |
rat |
| W K Chung, M Zheng, M Chua, E Kershaw, L Power-Kehoe, M Tsuji, X S Wu-Peng, J Williams, S C Chua, R L Leibe. Genetic modifiers of Leprfa associated with variability in insulin production and susceptibility to NIDDM. Genomics. vol 41. issue 3. 1997-07-01. PMID:9169130. |
in an attempt to identify the genetic basis for susceptibility to non-insulin-dependent diabetes mellitus within the context of obesity, we generated 401 genetically obese leprfa/leprfa f2 wky13m intercross rats that demonstrated wide variation in multiple phenotypic measures related to diabetes, including plasma glucose concentration, percentage of glycosylated hemoglobin, plasma insulin concentration, and pancreatic islet morphology. |
1997-07-01 |
2023-08-12 |
rat |
| A Sjöhol. Prostaglandins inhibit pancreatic beta-cell replication and long-term insulin secretion by pertussis toxin-insensitive mechanisms but do not mediate the actions of interleukin-1 beta. Biochimica et biophysica acta. vol 1313. issue 2. 1996-10-04. PMID:8781557. |
prostaglandins e1, e2, and f2 alpha suppressed beta-cell proliferation and long-term insulin secretion, thus mimicking the effects of il-1 beta. |
1996-10-04 |
2023-08-12 |
Not clear |
| R A Anderson, M M Polansk. Dietary and metabolite effects on trivalent chromium retention and distribution in rats. Biological trace element research. vol 50. issue 2. 1996-05-22. PMID:8605085. |
pharmacological doses of insulin, epinephrine, glucagon, and dibutyryladenosine-3'-5'cyclic monophosphate, prostaglandins a1, a2, b1, b2, e1, e2, f1 alpha, and f2 alpha did not significantly influence cr retention. |
1996-05-22 |
2023-08-12 |
rat |