| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena Predescu, Tudor Vaidean, Andreea-Marlena Rapciuc, Roxana Sipo. Metabolomic Markers in Attention-Deficit/Hyperactivity Disorder (ADHD) among Children and Adolescents-A Systematic Review. International journal of molecular sciences. vol 25. issue 8. 2024-04-27. PMID:38673970. |
synthesis revealed intricate links between adhd and altered amino acid metabolism, neurotransmitter dysregulation (especially dopamine and serotonin), oxidative stress, and the kynurenine pathway impacting neurotransmitter homeostasis. |
2024-04-27 |
2024-04-29 |
human |
| Ming Liu, Ping Deng, Guangyu Li, Haoling Liu, Junli Zuo, Wenwen Cui, Huixian Zhang, Xin Chen, Jingjing Yao, Xitian Peng, Lijun Peng, Jiao Liu, Wenting Zheng, Wei Yan, Ning Lua. Neurotoxicity of Combined Exposure to the Heavy Metals (Pb and As) in Zebrafish ( Toxics. vol 12. issue 4. 2024-04-26. PMID:38668505. |
to elucidate the underlying mechanisms, we examined changes in acetylcholinesterase (ache) activity, neurotransmitter (dopamine, 5-hydroxytryptamine) levels, hpi axis-related hormone (cortisol and epinephrine) contents and neurodevelopment-related gene expression in zebrafish brain. |
2024-04-26 |
2024-04-28 |
zebrafish |
| Zhenyu Zhang, Hua Zhao, Xiaoling Chen, Gang Tian, Guangmang Liu, Jingyi Cai, Gang Ji. Enhancing pig growth and gut health with fermented Jatropha curcas cake: Impacts on microbiota, metabolites, and neurotransmitters. Journal of animal physiology and animal nutrition. 2024-04-22. PMID:38648292. |
moreover, fjcc5 significantly boosted circulating neurotransmitter levels of 5-ht (p = 0.006) and gaba (p = 0.002) in plasma and hypothalamus, with corresponding increases in precursor amino acids (p < 0.05). |
2024-04-22 |
2024-04-26 |
Not clear |
| Sudeepa Bhattacharyya, Siamak MahmoudianDehkordi, Matthew J Sniatynski, Marina Belenky, Vasant R Marur, A John Rush, W Edward Craighead, Helen S Mayberg, Boadie W Dunlop, Bruce S Kristal, Rima Kaddurah-Daou. Metabolomics Signatures of serotonin reuptake inhibitor (Escitalopram), serotonin norepinephrine reuptake inhibitor (Duloxetine) and Cognitive Behavior Therapy on Key Neurotransmitter Pathways in Major Depressive Disorder. medRxiv : the preprint server for health sciences. 2024-04-18. PMID:38633777. |
metabolomics signatures of serotonin reuptake inhibitor (escitalopram), serotonin norepinephrine reuptake inhibitor (duloxetine) and cognitive behavior therapy on key neurotransmitter pathways in major depressive disorder. |
2024-04-18 |
2024-04-20 |
Not clear |
| Arubala P Reddy, Priyanka Rawat, Nicholas Rohr, Razelle Alvir, Jasbir Bisht, Mst Anika Bushra, Jennifer Luong, Aananya P Redd. Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis. Aging and disease. 2024-04-12. PMID:38607731. |
the neurotransmitter serotonin (5-hydroxytryptamine, 5-ht) is implicated mainly in alzheimer's disease (ad) and reported to be responsible for several processes and roles in the human body, such as regulating sleep, food intake, sexual behavior, anxiety, and drug abuse. |
2024-04-12 |
2024-04-15 |
human |
| Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth, Modi Niharika, Negi Preeya, Islam Rezau. Molecular Docking, MM-GBSA, and Molecular Dynamics Approach: 5-MeO-DMT Analogues as Potential Antidepressants. Archives of Razi Institute. vol 78. issue 5. 2024-04-09. PMID:38590677. |
the neurotransmitter serotonin has drawn the most attention concerning depression. |
2024-04-09 |
2024-04-11 |
Not clear |
| Roshani S Ganjare, Anjali A Vagga, Archana Dhok, Ashish Anjankar, Roshan K Jha, Pratiksha S Batulwa. Biochemical Abnormalities Associated With Sudden Infant Death Syndrome: A Case Report. Cureus. vol 16. issue 2. 2024-04-02. PMID:38562274. |
biochemical analysis of sids continued after post-mortem samples revealed dysregulation in neurotransmitter pathways, particularly serotonin, within the brain stem. |
2024-04-02 |
2024-04-04 |
Not clear |
| Liu Tang, Xiaoqin Cao, Shaoze Chen, Xiao Jiang, Dan Li, Guanghui Che. Dietary Galacto-oligosaccharides Ameliorate Atopic Dermatitis-like Skin Inflammation and Behavioral Deficits by Modulating Gut Microbiota-Brain-Skin Axis. Journal of agricultural and food chemistry. 2024-03-27. PMID:38536703. |
moreover, gos significantly improved the anxiety- and depressive-like symptoms as mirrored by the behavior tests including fst, tst, oft, and ezm through normalizing the neurotransmitter levels of 5-ht, da, ne, and cort in the brain. |
2024-03-27 |
2024-03-30 |
mouse |
| Ke Bo, Thomas E Kraynak, Mijin Kwon, Michael Sun, Peter J Gianaros, Tor D Wage. A systems identification approach using Bayes factors to deconstruct the brain bases of emotion regulation. Nature neuroscience. 2024-03-23. PMID:38519748. |
these systems covaried with individual differences in reappraisal success and were differentially related to neurotransmitter binding maps, implicating cannabinoid and serotonin systems in reappraisal. |
2024-03-23 |
2024-03-26 |
Not clear |
| Lina Bukowski, Markus Emanuel Strøm, Jens Lindengren Andersen, Jannick Bang Maesen, Lin Tian, Steffen Sinnin. 5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release. Scientific reports. vol 14. issue 1. 2024-03-20. PMID:38504103. |
the neurotransmitter serotonin plays a pivotal role in mood and depression. |
2024-03-20 |
2024-03-23 |
Not clear |
| Svetlana Adonina, Ekaterina Bazhenova, Darya Bazovkin. Effect of Short Photoperiod on Behavior and Brain Plasticity in Mice Differing in Predisposition to Catalepsy: The Role of BDNF and Serotonin System. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473717. |
both the neurotransmitter serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) are involved in the pathophysiological mechanisms underlying catalepsy and depressive disorders. |
2024-03-13 |
2024-03-15 |
mouse |
| Xintong Li, Tong Zheng, Jiayi Zhang, Haibo Chen, Chongdan Xiang, Yanan Sun, Yao Dang, Ping Ding, Guocheng Hu, Yunjiang Y. Photoaged polystyrene microplastics result in neurotoxicity associated with neurotransmission and neurodevelopment in zebrafish larvae (Danio rerio). Environmental research. 2024-02-24. PMID:38401682. |
motor neuron development was disrupted by transgenic (hb9-gfp) zebrafish larvae exposed to a-ps, with significant alterations in neurotransmitter levels (ach, da, 5-ht, and gaba) and enzyme activity (ache, chat, and che). |
2024-02-24 |
2024-02-27 |
zebrafish |
| Xia Wu, Ijaz Khan, Xiaoqi Ai, Jiliang Zhang, Haitao Shi, Ding Li, Meiling Hon. Effects of butyl paraben on behavior and molecular mechanism of Chinese striped-necked turtle (Mauremys sinensis). Aquatic toxicology (Amsterdam, Netherlands). vol 268. 2024-02-06. PMID:38320419. |
the analysis of neurotransmitter in the brain showed that 5-hydroxytryptamine (5-ht) contents in the groups of 500 and 5000 µg/l were significantly higher than the other groups, which was due to an increase in the mrna relative expression levels of the 5-ht receptor gene (5-htr), neurotransmitter transporter genes (drd4, slc6a4), and neurotransmitter synthase tryptophan hydroxylase (tph). |
2024-02-06 |
2024-02-09 |
Not clear |
| Li Cui, Yongzhi Hua, Shuting Zou, Chao Gu, Hui L. Combination of fenchone and sodium hyaluronate ameliorated constipation-predominant irritable bowel syndrome and underlying mechanisms. Chemical biology & drug design. vol 103. issue 1. 2024-01-17. PMID:38030381. |
the neurotransmitter levels, including substance p (sp), motilin (mtl), 5-hydroxytryptamine (5-ht), and vasoactive intestinal peptide (vip), were determined by elisa methods. |
2024-01-17 |
2024-01-19 |
rat |
| Ralph Gradisch, Katharina Schlögl, Erika Lazzarin, Marco Niello, Julian Maier, Felix P Mayer, Leticia Alves da Silva, Sophie M C Skopec, Randy D Blakely, Harald H Sitte, Marko D Mihovilovic, Thomas Stockne. Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors. Nature communications. vol 15. issue 1. 2024-01-09. PMID:38195746. |
the presynaptic serotonin transporter (sert) clears extracellular serotonin following vesicular release to ensure temporal and spatial regulation of serotonergic signalling and neurotransmitter homeostasis. |
2024-01-09 |
2024-01-13 |
human |
| Zhuhong Yang, Zixu Zhang, Xiping Long, Xuqi Shi, Di Wang, Deliang Peng, Shan Ye, Zhong Din. Clarifying the functional role of serotonin in Phytopathology. 2023-12-26. PMID:38148161. |
clarifying the functional role of serotonin in serotonin (5-hydroxytryptamine, 5-ht) is an essential neurotransmitter involved in regulating various behaviors in plant-parasitic nematodes (ppns), including locomotion, egg laying, feeding, and mating. |
2023-12-26 |
2023-12-29 |
caenorhabditis_elegans |
| Computational And Mathematical Methods In Medicin. Retracted: Brain Network for Exploring the Change of Brain Neurotransmitter 5-Hydroxytryptamine of Autism Children by Resting-State EEG. Computational and mathematical methods in medicine. vol 2023. 2023-12-21. PMID:38124983. |
retracted: brain network for exploring the change of brain neurotransmitter 5-hydroxytryptamine of autism children by resting-state eeg. |
2023-12-21 |
2023-12-23 |
Not clear |
| Soraia Silva, Carla Fonseca, Joana Bicker, Amílcar Falcão, Ana Fortun. Intranasal administration of sertraline ensures sustained brain delivery and antidepressant effect in a mouse model of depression. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2023-12-13. PMID:38092320. |
noteworthy neurotransmitter alterations were observed, with in sertraline markedly reducing adrenaline in the prefrontal cortex, while serotonin and melatonin increased following both administration routes. |
2023-12-13 |
2023-12-17 |
mouse |
| Saniye Özcan, Aysun Geven, Murat Kozanlı, Nafiz Öncü Ca. The Development and Full Validation of a Novel Liquid Chromatography Electrochemical Detection Method for Simultaneous Determination of Nine Catecholamines in Rat Brain. Turkish journal of pharmaceutical sciences. vol 20. issue 5. 2023-11-07. PMID:37933822. |
in the current study; for the first time, an optimized and fully validated high-performance liquid chromatography-electrochemical detection (hplc-ec) method according to food and drug administration and european medicines agency bioanalytical validation guidance was developed for the simultaneous analysis of nine neurotransmitter compounds, namely dopamine, homovanilic acid, vanilmandelic acid, serotonin (ser), 5-hydroxyindole-3-acetic acid, 4-hydroxy-3-methoxyphenylglycol, norepinephrine, 3,4 dihydroxyphenylacetic acid, and 3-methoxytyramine and simultaneously determined in rat brain samples. |
2023-11-07 |
2023-11-08 |
rat |
| Enav Z Zusman, Cecil M Y Chau, Jeffrey N Bone, Kaia Hookenson, Ursula Brain, Melissa B Glier, Ruth E Grunau, Joanne Weinberg, Angela M Devlin, Tim F Oberlande. Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study. Developmental psychobiology. vol 65. issue 7. 2023-10-20. PMID:37860904. |
prenatal exposure to maternal depression and serotonin reuptake inhibitor (sri) antidepressants both affect the development of the hypothalamic-pituitary-adrenal (hpa) system, possibly via the neurotransmitter serotonin (5ht). |
2023-10-20 |
2023-11-08 |
Not clear |