| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Timea Andrea Bochiș, Kálmán Imre, Simona Marc, Cristina Vaduva, Tiana Florea, János Dégi, Octavian Sorin Voia, Călin Pop, Ioan Ţibr. The Variation of Serotonin Values in Dogs in Different Environmental Conditions. Veterinary sciences. vol 9. issue 10. 2022-10-26. PMID:36288136. |
serotonin is considered to be the neurotransmitter that controls several types of behavior: aggressiveness, impulsivity, food selection, stimulation, sexual behavior, reaction to pain, and emotional manifestations. |
2022-10-26 |
2023-08-14 |
Not clear |
| Daisuke Ib. Role of interaction of mGlu2 and 5-HT Pharmacology, biochemistry, and behavior. 2022-10-16. PMID:36244526. |
role of interaction of mglu2 and 5-ht the serotonergic and glutamatergic neurotransmitter systems have been implicated in the pathophysiology of schizophrenia, and increasing evidence shows that they interact functionally. |
2022-10-16 |
2023-08-14 |
Not clear |
| Saida Oubraim, Ruixiang Wang, Kathryn Hausknecht, Martin Kaczocha, Roh-Yu Shen, Samir Haj-Dahman. Prenatal ethanol exposure causes anxiety-like phenotype and alters synaptic nitric oxide and endocannabinoid signaling in dorsal raphe nucleus of adult male rats. Translational psychiatry. vol 12. issue 1. 2022-10-10. PMID:36216807. |
prenatal ethanol exposure is associated with persistent dysfunctions of several neurotransmitter systems, including the serotonin (5-ht) system, which plays a major role in mood regulation and stress homeostasis. |
2022-10-10 |
2023-08-14 |
rat |
| Ping Tian, Wei Zhang, Kai-Yan Li, Hong-Wei Li, Kai Ma, De-En Ha. [Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164876. |
the results suggested that rehmanniae radix improved depression-like behavior of cums rats, and the mechanism might be related to the regulation of synthesis, transportation, and metabolism of 5-ht neurotransmitter in the hippocampus. |
2022-09-27 |
2023-08-14 |
rat |
| Mu Li, Qingyang Chen, Yuan-Wei Zhan. Determining Ligand and Ion-Induced Conformational Changes in Serotonin Transporter with Its Fluorescent Substrates. International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142837. |
the serotonin transporter (sert) catalyzes reuptake of the neurotransmitter serotonin after its release by serotonergic neurons and is the molecular target for antidepressant drugs and psychostimulants. |
2022-09-23 |
2023-08-14 |
Not clear |
| Lasse Brandt, Shuyan Liu, Christine Heim, Andreas Hein. The effects of social isolation stress and discrimination on mental health. Translational psychiatry. vol 12. issue 1. 2022-09-21. PMID:36130935. |
animal models indicate that social separation stress, particularly in early life, activates the hypothalamic-pituitary-adrenal axis and interacts with monoaminergic, glutamatergic, and gabaergic neurotransmitter systems, inducing long-lasting reductions in serotonin turnover and alterations in dopamine receptor sensitivity. |
2022-09-21 |
2023-08-14 |
human |
| Giulia Braccagni, Simona Scheggi, Marco Bortolat. Elevated levels of serotonin 5-HT European archives of psychiatry and clinical neuroscience. 2022-09-12. PMID:36094569. |
while ample evidence points to a critical role of serotonin in the emotional modulation of social responses, the implication of this neurotransmitter in asb is unclear. |
2022-09-12 |
2023-08-14 |
human |
| Christopher J O'Connell, Evan L Reeder, Sean M Collins, Kainat Lungani, Sophia V Norman, Matthew J Robso. Mild traumatic brain injury elicits time- and region-specific reductions in serotonin transporter protein expression and uptake capacity. Neuroreport. vol 33. issue 14. 2022-09-05. PMID:36062511. |
the monoamine neurotransmitter serotonin (5-ht) is important for the regulation of behavior, and aberrations in 5-ht signaling are linked to several neuropsychiatric and neurodevelopmental disorders. |
2022-09-05 |
2023-08-14 |
Not clear |
| I-Chen Huang, Tsui-San Chang, Chiehfeng Chen, Jia-Ying Sun. Effect of Vortioxetine on Cognitive Impairment in Patients With Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. The international journal of neuropsychopharmacology. 2022-08-18. PMID:35981958. |
vortioxetine is a new antidepressant with multipharmacological actions that elevate the concentration of serotonin and modulate multiple neurotransmitter receptors in the brain. |
2022-08-18 |
2023-08-14 |
Not clear |
| Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Xitan Hou, Jia Cai, Yu Huang, Jichang Jia. Serotonin system is partially involved in immunomodulation of Nile tilapia ( Frontiers in immunology. vol 13. 2022-08-15. PMID:35967362. |
serotonin system is partially involved in immunomodulation of nile tilapia ( serotonin (5-hydroxytryptamine) is a well-known neurotransmitter affecting emotion, behavior, and cognition. |
2022-08-15 |
2023-08-14 |
Not clear |
| Lauren Malave, Milenna T van Dijk, Christoph Anacke. Early life adversity shapes neural circuit function during sensitive postnatal developmental periods. Translational psychiatry. vol 12. issue 1. 2022-08-01. PMID:35915071. |
we provide converging evidence from human and animal studies on how ela alters the functional development of brain regions, neural circuits, and neurotransmitter systems that are crucial for cognition and affective behavior, including the hippocampus, the hypothalamus-pituitary-adrenal (hpa) axis, neural networks of fear responses and cognition, and the serotonin (5-ht) system. |
2022-08-01 |
2023-08-14 |
human |
| Anna Grete Wessel. Influence of the Gut Microbiome on Feed Intake of Farm Animals. Microorganisms. vol 10. issue 7. 2022-07-27. PMID:35889024. |
based on current evidence, the major mediators appear to be short-chain fatty acids (scfa), peptide hormones such as peptide yy (pyy) and glucagon-like peptide-1 (glp-1), as well as the amino acid tryptophan with the associated neurotransmitter serotonin, dopamine and γ-aminobutyrate (gaba). |
2022-07-27 |
2023-08-14 |
Not clear |
| Teresa Schmidt, Sebastian Meller, Steven R Talbot, Benjamin A Berk, Tsz H Law, Sarah L Hobbs, Nina Meyerhoff, Rowena M A Packer, Holger A Vol. Urinary Neurotransmitter Patterns Are Altered in Canine Epilepsy. Frontiers in veterinary science. vol 9. 2022-06-02. PMID:35651965. |
a significant difference between urinary neurotransmitter levels (glycine, serotonin, norepinephrine/epinephrine ratio, ɤ-aminobutyric acid/glutamate ratio) of dogs diagnosed with idiopathic epilepsy and the control group was found, when sex and neutering status were accounted for. |
2022-06-02 |
2023-08-13 |
human |
| Waisley Yang, Rohit Singla, Oshin Maheshwari, Christine J Fontaine, Joana Gil-Mohape. Alcohol Use Disorder: Neurobiology and Therapeutics. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625928. |
ethanol exerts its toxicity through changes to multiple neurotransmitter systems, including serotonin, dopamine, gamma-aminobutyric acid, glutamate, acetylcholine, and opioid systems. |
2022-05-28 |
2023-08-13 |
Not clear |
| Pravat Dhakal, Sana I Chaudhry, Rossana Signorelli, Kevin M Collin. Serotonin signals through postsynaptic Gαq, Trio RhoGEF, and diacylglycerol to promote C. elegans egg-laying circuit activity and behavior. Genetics. 2022-05-17. PMID:35579369. |
these results support a model where serotonin signaling through gαq, plcβ, and unc-13 promote neurotransmitter release, and that serotonin also signals through gαq, trio rhogef, and an unidentified, pma-responsive effector to promote postsynaptic muscle excitability. |
2022-05-17 |
2023-08-13 |
caenorhabditis_elegans |
| Amy Fassler, Davis Rens, Ruhi Shah, Kennan Chojnacki, Kai Ren. Understanding of the Serotonin Transporter Mechanism-Targeting Drug Therapy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555773. |
the sert protein re-uptakes 5-ht during its release, leading to the regulation of the neurotransmitter's concentration in the synaptic cleft. |
2022-05-13 |
2023-08-13 |
Not clear |
| Jason N. The Treatment of Psychotic Depression in a 64-Year-Old Patient With Carcinoid Syndrome. Cureus. vol 14. issue 4. 2022-05-09. PMID:35530836. |
the treatment of the neuropsychiatric manifestations of the disease is also complicated by the concurrent use of somatostatin analogues, which also affect total circulating serotonin levels, a neurotransmitter implicated in the aforementioned psychiatric disorders. |
2022-05-09 |
2023-08-13 |
Not clear |
| Mengying Wei, Yuanyuan Liu, Zifeng Pi, Kexin Yue, Shizhe Li, Mingxin Hu, Zhiqiang Liu, Fengrui Song, Zhongying Li. Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer's disease rat induced by amyloid beta 25-35. RSC advances. vol 9. issue 32. 2022-05-06. PMID:35515227. |
the neurotransmitter dysfunction was mainly involved in γ-aminobutyric acid (gaba), acetyl choline (ach), glutamic acid (glu), 5-hydroxytryptamine (5-ht), dopamine (da) and norepinephrine (ne). |
2022-05-06 |
2023-08-13 |
rat |
| Jun Shao, Fan Zhang, Chuanzhi Chen, Ye Wang, Qiang Wang, Jie Zho. Brain Network for Exploring the Change of Brain Neurotransmitter 5-Hydroxytryptamine of Autism Children by Resting-State EEG. Computational and mathematical methods in medicine. vol 2022. 2022-05-03. PMID:35502411. |
brain network for exploring the change of brain neurotransmitter 5-hydroxytryptamine of autism children by resting-state eeg. |
2022-05-03 |
2023-08-13 |
Not clear |