| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isabel Ellerbrock, Angelica Sandström, Jeanette Tour, Silvia Fanton, Diana Kadetoff, Martin Schalling, Karin B Jensen, Rouslan Sitnikov, Eva Kose. Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:33980291. |
the neurotransmitter serotonin, involved in the regulation of pain and emotion, is critically regulated by the 5-ht |
2021-08-12 |
2023-08-13 |
human |
| Surojit Karmakar, Girdhari La. Role of serotonin receptor signaling in cancer cells and anti-tumor immunity. Theranostics. vol 11. issue 11. 2021-07-28. PMID:33859748. |
serotonin or 5-hydroxytryptamine (5-ht) is a neurotransmitter known to affect emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases. |
2021-07-28 |
2023-08-13 |
Not clear |
| Caroline Fratelli, Jhon Siqueira, Calliandra Silva, Eduardo Ferreira, Izabel Silv. 5HTTLPR Genetic Variant and Major Depressive Disorder: A Review. Genes. vol 11. issue 11. 2021-07-23. PMID:33114535. |
the scl6a4 protein (5httlpr) functions transporting serotonin, a neurotransmitter linked to mood and emotion, to the synaptic cleft. |
2021-07-23 |
2023-08-13 |
Not clear |
| Marina Rieder, Nadine Gauchel, Christoph Bode, Daniel Duerschmie. Serotonin: a platelet hormone modulating cardiovascular disease. Journal of thrombosis and thrombolysis. vol 52. issue 1. 2021-07-21. PMID:33155668. |
serotonin 5-hydroxytryptamin (5-ht), a biogenic amine acting as a neurotransmitter and a peripheral hormone, is involved in the pathogenesis of both, cardiovascular disease and depression. |
2021-07-21 |
2023-08-13 |
Not clear |
| Sherri Cofield Kroll, Carole Frances Bennett, Tarah Winter Klinefelte. Update on Neurodegenerative Diseases and Glutamate: A PMHNP Single Case Study Report of a Diagnostically Complex Adult Patient, Interventions, and Unexpected Outcomes. Journal of the American Psychiatric Nurses Association. 2021-07-09. PMID:34238041. |
while dysfunction of serotonin and dopamine neurotransmitters has been studied in depth, in regard to the etiology of mental illness, the neurotransmitter glutamate and its dysfunction is now being explored as contributing to neurodegenerative psychiatric diseases, schizophrenia, autism, depression, and alzheimer's disease. |
2021-07-09 |
2023-08-13 |
Not clear |
| Alok Joshi, Da-Hui Wang, Steven Watterson, Paula L McClean, Chandan K Behera, Trevor Sharp, KongFatt Wong-Li. Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease. Neuropharmacology. vol 174. 2021-07-07. PMID:32380022. |
over the last decade, there has been increased attention towards novel drugs, targeting alternative neurotransmitter pathways, particularly those targeting serotonergic (5-ht) system. |
2021-07-07 |
2023-08-13 |
Not clear |
| Clarissa M D Mota, Luiz G S Branco, Shaun F Morrison, Christopher J Madde. Systemic serotonin inhibits brown adipose tissue sympathetic nerve activity via a GABA input to the dorsomedial hypothalamus, not via 5HT Acta physiologica (Oxford, England). vol 228. issue 3. 2021-06-30. PMID:31599481. |
systemic serotonin inhibits brown adipose tissue sympathetic nerve activity via a gaba input to the dorsomedial hypothalamus, not via 5ht serotonin (5-hydroxytryptamine, 5-ht), an important neurotransmitter and hormone, modulates many physiological functions including body temperature. |
2021-06-30 |
2023-08-13 |
Not clear |
| Bichu Cheng, Johannes Morstein, Lucy Kate Ladefoged, Jannick Bang Maesen, Birgit Schiøtt, Steffen Sinning, Dirk Traune. A Photoswitchable Inhibitor of the Human Serotonin Transporter. ACS chemical neuroscience. vol 11. issue 9. 2021-06-18. PMID:32275382. |
the human serotonin transporter (hsert) terminates serotonergic signaling through reuptake of neurotransmitter into presynaptic neurons and is a target for many antidepressant drugs. |
2021-06-18 |
2023-08-13 |
human |
| Yuanhui Zhu, Fei Huan, Junfeng Wang, Xuexue Xie, Guoqin Yu, Xi Wang, Lei Jiang, Rong Gao, Hang Xiao, Haixia Ding, Jun Wan. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Parkinson's Disease in Mouse: Potential Association between Neurotransmitter Disturbance and Gut Microbiota Dysbiosis. ACS chemical neuroscience. vol 11. issue 20. 2021-06-18. PMID:32926778. |
meanwhile, the tryptophan (trp) and tyrosine (tyr) neurotransmitter metabolites involving kynurenine (kyn), serotonin (5-ht), and dopamine (da) pathways were significantly changed in serum. |
2021-06-18 |
2023-08-13 |
mouse |
| Andrei Turkin, Oksana Tuchina, Friederike Klempi. Microglia Function on Precursor Cells in the Adult Hippocampus and Their Responsiveness to Serotonin Signaling. Frontiers in cell and developmental biology. vol 9. 2021-06-12. PMID:34109176. |
recent evidence shows that microglia interact with serotonin, the neurotransmitter crucially involved in adult neurogenesis, and known for its role in antidepressant action. |
2021-06-12 |
2023-08-13 |
Not clear |
| T V Davydova, M A Gruden, V S Kudrin, V B Narkevich, L A Vetrile, I A Zakharova, R D E Sewel. Antibodies to Glutamate Facilitate Spatial Memory Formation in the Morris Water Maze in Aging C57BL/6 mice. Bulletin of experimental biology and medicine. vol 169. issue 1. 2021-06-01. PMID:32474668. |
in animals treated with glutamate antibodies, the content of serotonin and dopamine metabolites 3-mt and hva in the hippocampus decreased, but no changes in the metabolism of neurotransmitter acids were revealed. |
2021-06-01 |
2023-08-13 |
mouse |
| Qingmin Kong, Botao Wang, Peijun Tian, Xiu Li, Jianxin Zhao, Hao Zhang, Wei Chen, Gang Wan. Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation. Food & function. vol 12. issue 6. 2021-06-01. PMID:33629689. |
while improving autistic-like behavioral symptoms, we found l. helveticus ccfm1076 was more beneficial in regulating 5ht anabolism and catabolism, balancing excitatory and inhibitory neurotransmitter release in the pns and cns, and increasing oxytocin (ot) synthesis in the hypothalamus. |
2021-06-01 |
2023-08-13 |
rat |
| Omar K Sial, Eric M Parise, Lyonna F Parise, Tamara Gnecco, Carlos A Bolaños-Guzmá. Ketamine: The final frontier or another depressing end? Behavioural brain research. vol 383. 2021-05-25. PMID:32017978. |
although the prominent understanding has been that ketamine's mode of action is mediated solely via the nmda receptor, this view has been challenged by reports implicating other glutamate receptors such as ampa, and other neurotransmitter systems such as serotonin and opioids in the antidepressant response. |
2021-05-25 |
2023-08-13 |
Not clear |
| Hera Wu, DeVon Herr, Nancie J MacIver, Jeffrey C Rathmell, Valerie A Gerriet. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. International immunopharmacology. vol 88. 2021-05-25. PMID:32866787. |
5-ht is well known as a neurotransmitter and recently has been recognized to play a role in the immune response; however, little is known about the immune cell type-specific expression of the serotonergic machinery and receptors. |
2021-05-25 |
2023-08-13 |
Not clear |
| Zhifeng Zhong, Simin Zhou, Bin Xiang, Yu Wu, Jiaxin Xie, Peng L. Association of Peripheral Plasma Neurotransmitters with Cognitive Performance in Chronic High-altitude Exposure. Neuroscience. vol 463. 2021-05-19. PMID:33540052. |
consistent with this result, peripheral plasma dopa, dopamine, serotonin, 5-hiaa and glutamate were associated with brain neurotransmitter levels after chronic hh exposure in rats. |
2021-05-19 |
2023-08-13 |
rat |
| Qinghua Wu, Dawei Guo, Hui Jia, Eugenie Nepovimova, Wenda Wu, Kamil Kuc. The trichothecene neosolaniol stimulates an emetic response through neuropeptide Y2 and serotonin 3 receptors in mink. Toxicology. vol 452. 2021-05-12. PMID:33581213. |
trichothecenes have been previously demonstrated to induce emetic responses in mink, and this response has been associated with neurotransmitter peptide yy (pyy) and serotonin (5-hydroxytryptamine, 5-ht). |
2021-05-12 |
2023-08-13 |
human |
| Madhusmita P Sahu, Yago Pazos-Boubeta, Anna Steinzeig, Katja Kaurinkoski, Michela Palmisano, Olgierd Borowecki, Timo Petteri Piepponen, Eero Castré. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Frontiers in molecular neuroscience. vol 14. 2021-05-04. PMID:33935645. |
neurotrophin brain-derived neurotrophic factor (bdnf) and neurotransmitter serotonin (5-ht) regulate each other and have been implicated in several neuronal mechanisms, including neuroplasticity. |
2021-05-04 |
2023-08-13 |
mouse |
| William Roth, Kimia Zadeh, Rushi Vekariya, Yong Ge, Mansour Mohamadzade. Tryptophan Metabolism and Gut-Brain Homeostasis. International journal of molecular sciences. vol 22. issue 6. 2021-04-30. PMID:33804088. |
it is the only precursor for the neurotransmitter serotonin, which is vital for the processing of emotional regulation, hunger, sleep, and pain, as well as colonic motility and secretory activity in the gut. |
2021-04-30 |
2023-08-13 |
Not clear |
| Ria Fisher, Atsuko Hikima, Rebecca Morris, Michael J Jackson, Sarah Rose, Mark A Varney, Ronan Depoortere, Adrian Newman-Tancred. The selective 5-HT Neuropharmacology. vol 167. 2021-04-23. PMID:32057799. |
the selective 5-ht l-dopa is the gold-standard pharmacotherapy for treatment of parkinson's disease (pd) but can lead to the appearance of troubling dyskinesia which are attributable to 'false neurotransmitter' release of dopamine by serotonergic neurons. |
2021-04-23 |
2023-08-13 |
Not clear |
| Tingting Xi, Jinlin W. A Review on the Mechanism Between Different Factors and the Occurrence of Autism and ADHD. Psychology research and behavior management. vol 14. 2021-04-17. PMID:33859505. |
in addition, other neurotransmitter such as norepinephrine (ne) and serotonin (5-ht) signaling factors coming down to these two neurodevelopmental disorders and how their abnormal concentration present in the blood as well as the completely opposite results among experimental groups and control group will be elaborated. |
2021-04-17 |
2023-08-13 |
Not clear |