| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Georgia E Hodes, Debra Bangasser, Ioannis Sotiropoulos, Nikolaos Kokras, Christina Dall. Sex Differences in Stress Response: Classical Mechanisms and Beyond. Current neuropharmacology. 2023-10-19. PMID:37855285. |
then, we present sex differences in neurotransmitter levels, such as serotonin, dopamine, glutamate and gaba, as well as indices of neurodegeneration, such as amyloid β and tau. |
2023-10-19 |
2023-11-08 |
Not clear |
| Xin Wang, Feida Che, Xin Zhang, Ping Li, Wen Zhang, Bo Tan. Tracing Superoxide Anion in Serotonergic Neurons of Living Mouse Brains with Depression by Small-Molecule Fluorescence Probes. Analytical chemistry. 2023-10-13. PMID:37830753. |
in brains, the serotonergic neurons are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the physiology of the brain. |
2023-10-13 |
2023-10-15 |
mouse |
| Alireza Majdi, Boateng Asamoah, Myles Mc Laughli. Understanding Neuromodulation Pathways in tDCS: Brain Stem Recordings in Rat During Trigeminal Nerve Direct Current Stimulation. bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745349. |
these nuclei exert control over brainstem centers regulating neurotransmitter release, such as serotonin and norepinephrine, potentially affecting global brain activity. |
2023-09-25 |
2023-10-07 |
rat |
| Yan Wang, Yuzhen Huang, Min Zhao, Lu Yang, Kunhan Su, Hao Wu, Yuting Wang, Qing Chang, Wanli Li. Zuojin pill improves chronic unpredictable stress-induced depression-like behavior and gastrointestinal dysfunction in mice via the theTPH2/5-HT pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 120. 2023-09-16. PMID:37716030. |
the complex bidirectional communication between the gastrointestinal tract and the brain is associated with mental disorders such as depression; serotonin, as a crucial neurotransmitter in the communication system between the central nervous system and the gastrointestinal tract, has effects on regulating gastrointestinal motility and sensation and improving psychosomatic status. |
2023-09-16 |
2023-10-07 |
mouse |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
to direct outgrowth, serotonergic neurons utilize serotonin as a signaling molecule prior to it assuming its neurotransmitter role. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Yurim Shin, Seungjik Kim, Jong-Woo Soh. Serotonergic regulation of appetite and sodium appetite. Journal of neuroendocrinology. 2023-08-01. PMID:37525500. |
serotonin is a neurotransmitter that is synthesized and released from the brainstem raphe nuclei to affect many brain functions. |
2023-08-01 |
2023-08-14 |
Not clear |
| Anjali Suman, Archisman Mahapatra, Priya Gupta, Shubhendu Shekhar Ray, Rahul Kumar Sing. Polystyrene microplastics modulated bdnf expression triggering neurotoxicity via apoptotic pathway in zebrafish embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-07-16. PMID:37454885. |
on the last day of exposure, behaviour, accumulation, embryotoxicity, acridine orange staining, antioxidant enzyme assay, acetylcholinesterase assay, nitric oxide (no) estimation, along with neurotransmitter (serotonin, dopamine) quantification and gene expression using qrt-pcr (bdnf, p53, bcl-2, caspase-3, caspase-9) were performed. |
2023-07-16 |
2023-08-14 |
human |
| Dongxue Yang, Zhiyu Zhao, Emad Tajkhorshid, Eric Gouau. Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 29. 2023-07-13. PMID:37436958. |
the serotonin transporter (sert) is a member of the slc6 neurotransmitter transporter family that mediates serotonin reuptake at presynaptic nerve terminals. |
2023-07-13 |
2023-08-14 |
Not clear |
| Carla Fonseca, Miren Ettcheto, Joana Bicker, Maria José Fernandes, Amílcar Falcão, Antoni Camins, Ana Fortun. Under the umbrella of depression and Alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? Ageing research reviews. 2023-07-06. PMID:37414155. |
besides the well-known imbalance of neurotransmitter levels, including serotonin, noradrenaline, dopamine and glutamate, recent scientific evidence highlights aberrant spine density, neuroinflammation, dysregulation of neurotrophic factor levels and formation of amyloid beta (aβ) peptides, as the main physiopathological mechanisms compromised in depression and ad. |
2023-07-06 |
2023-08-14 |
Not clear |
| Zhelun Peng, Qiu Man, Lu Meng, Sheng Wang, Hao Cai, Chuansheng Zhang, Xianyao Li, Heng Wang, Guiyu Zh. A PITX2-HTR1B pathway regulates the asymmetric development of female gonads in chickens. PNAS nexus. vol 2. issue 6. 2023-06-30. PMID:37388922. |
integrated chromatin immunoprecipitation sequencing (chip-seq) and rna sequencing (rna-seq) analyses indicated that pitx2 directly binds to the promoters of genes encoding neurotransmitter receptors and leads to left-biased expression of both serotonin and dopamine receptors. |
2023-06-30 |
2023-08-14 |
Not clear |
| Meghan Pantalia, Zhi Lin, Samantha J Tener, Bing Qiao, Grace Tang, Matthew Ulgherait, Reed O'Connor, Rebecca Delventhal, Julia Volpi, Sheyum Syed, Nissim Itzhak, Julie C Canman, María de la Paz Fernández, Mimi Shirasu-Hiz. Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior. Scientific reports. vol 13. issue 1. 2023-06-27. PMID:37369755. |
inhibitors of enzymes that inactivate amine neurotransmitters (dopamine, serotonin), such as catechol-o-methyltransferase (comt) and monoamine oxidase (mao), are thought to increase neurotransmitter levels and are widely used to treat parkinson's disease and psychiatric disorders, yet the role of these enzymes in regulating behavior remains unclear. |
2023-06-27 |
2023-08-14 |
drosophila_melanogaster |
| Sukhbir Kaur, Angela Lopez-Ramirez, Taylor M Hickman, Michael P Hunter, Dayna L Averit. EXPRESSION OF SEROTONIN RECEPTOR SUBTYPE 3A (5HT3A) ON RAT TRIGEMINAL SENSORY NEURONS. Texas journal of microscopy. vol 52. issue 1. 2023-06-13. PMID:37309469. |
serotonin (5-hydroxytryptamine, 5ht) is a neurotransmitter and proinflammatory mediator found largely in the peripheral nervous system where it can initiate pain signaling. |
2023-06-13 |
2023-08-14 |
rat |
| Shuchang Zhao, Kiryl D Piatkevic. Techniques for in vivo serotonin detection in the brain: State of the art. Journal of neurochemistry. 2023-06-09. PMID:37293767. |
neuronal circuits in the brain that utilize the neurotransmitter serotonin are essential to the regulation of mood and emotional expression. |
2023-06-09 |
2023-08-14 |
Not clear |
| Brent W Bisgrove, Robert D Burk. Development of Serotonergic Neurons in Embryos of the Sea Urchin, Strongylocentrotus purpuratus: (serotonergic/neural development/embryo/echinoid). Development, growth & differentiation. vol 28. issue 6. 2023-06-07. PMID:37281792. |
the development of the serotonergic component of the nervous system of larvae of s. purpuratus is traced using indirect immunofluorescence with a polyclonal antibody against the neurotransmitter serotonin. |
2023-06-07 |
2023-08-14 |
Not clear |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
oxytocin (oxt) modulates wide spectrum of social and emotional behaviors via modulation of numerous neurotransmitter systems, including serotonin (5-ht). |
2023-05-30 |
2023-08-14 |
Not clear |
| Dan Dong, Xiaofeng Liu, Lijiang Ma, Yu Lei Hao, Li Zhang, Meiying Song, Zhonggao Xu, Hua Zha. Dapagliflozin inhibits the activity of lateral habenula to alleviate diabetes mellitus-induced depressive-like behavior. Experimental neurology. 2023-05-21. PMID:37211324. |
behavioral tests, western blotting, immunohistochemistry, and neurotransmitter assays were used to determine the effects of dapagliflozin on the behavior of dm rats, amp-activated protein kinase (ampk) pathway and c-fos expression in the lhb and 5-hydroxyindoleacetic acid (5-hiaa)/5-hydroxytryptamine (5-ht) ratio in the dorsal raphe nucleus (drn). |
2023-05-21 |
2023-08-14 |
rat |
| Matthew Meyer, Jason Slo. The Evolution and Ecology of Psilocybin in Nature. Fungal genetics and biology : FG & B. 2023-05-20. PMID:37210028. |
the structural and functional similarities of psiloids to serotonin, an essential neurotransmitter in animals, suggest that they may enhance the fitness of fungi through interference with serotonergic processes. |
2023-05-20 |
2023-08-14 |
human |
| Troels Boldt Rømer, Rose Jeppesen, Rune Haubo Bojesen Christensen, Michael Eriksen Benro. Biomarkers in the cerebrospinal fluid of patients with psychotic disorders compared to healthy controls: a systematic review and meta-analysis. Molecular psychiatry. 2023-05-11. PMID:37169812. |
patients showed increased levels of noradrenaline (standardized mean difference/smd, 0.53; 95% confidence interval/ci, 0.16 to 0.90) and its metabolite 3-methoxy-4-hydroxyphenylglycol (smd, 0.30; 95% ci: 0.05 to 0.55), the serotonin metabolite 5-hydroxyindoleacetic acid (smd, 0.11; 95% ci: 0.01 to 0.21), the pro-inflammatory neurotransmitter kynurenic acid (smd, 1.58; 95% ci: 0.34 to 2.81), its precursor kynurenine (smd,0.99; 95% ci: 0.60 to 1.38), the cytokines interleukin-6 (smd, 0.58; 95% ci: 0.39 to 0.77) and interleukin-8 (smd, 0.43; 95% ci: 0.24 to 0.62), the endocannabinoid anandamide (smd, 0.78; 95% ci: 0.53 to 1.02), albumin ratio (smd, 0.40; 95% ci: 0.08 to 0.72), total protein (smd, 0.29; 95% ci: 0.16 to 0.43), immunoglobulin ratio (smd, 0.45; 95% ci: 0.06 to 0.85) and glucose (smd, 0.48; 95% ci: 0.01 to 0.94). |
2023-05-11 |
2023-08-14 |
Not clear |
| Shun Hao, Wantong Shi, Weiqi Liu, Qi-Yu Chen, Min Zhu. Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety. Frontiers in synaptic neuroscience. vol 15. 2023-05-05. PMID:37143481. |
serotonin (5-ht) in the central nervous system (cns) has been recognized as an important neurotransmitter and neuromodulator which regulates various physiological functions, such as pain sensation, cognition, and emotions-especially anxiety and depression. |
2023-05-05 |
2023-08-14 |
Not clear |
| Kana Harada, Ryoma Sho, Hiromiki Takakura, Eri Yokoyama, Reika Koyama, Yuka Yamamoto, Naoko Adachi, Shigeru Tanaka, Izumi Hide, Norio Saka. S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake. Biochemical and biophysical research communications. vol 662. 2023-04-26. PMID:37099811. |
the neurotransmitter serotonin (5-ht) is transported back into serotonergic neurons by the serotonin transporter (sert). |
2023-04-26 |
2023-08-14 |
human |