| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beth A Luellen, Diane B Miller, Angela C Chisnell, Dennis L Murphy, James P O'Callaghan, Anne Milasincic Andrew. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14561848. |
these results demonstrate the importance of obtaining quantitative assessments of gfap to detect astroglial responses associated with selective damage to neurotransmitter systems with low-density innervation and suggest that serotonin may facilitate the astrocytic response to striatal injury. |
2004-01-29 |
2023-08-12 |
mouse |
| Y Ozawa, S Takashim. Developmental neurotransmitter pathology in the brainstem of sudden infant death syndrome: a review and sleep position. Forensic science international. vol 130 Suppl. 2003-01-02. PMID:12350301. |
in sids infants, there are an increase of glial fibrillary acidic protein (gfap)-positive astrocytes in the brainstem, an increase of substance p (sp) in the medulla and pons, a decrease of tyrosine hydroxylase (th)-positive catecholaminergic neurons in the ventrolateral medulla (vlm), and vagal nuclei in the medulla oblongata and basal ganglia, a decrease of tryptophan hydroxylase (trh)-positive serotonergic neurons in the periaqueductal gray matter (pag), and decreases of 5-hydroxytryptamine 1a (5-ht1a) and 5-ht2a receptor immunoreactivities in the vlm and vagal nuclei in the medulla oblongata. |
2003-01-02 |
2023-08-12 |
Not clear |
| Audrey Petit, Nancy Quenneville, Annie Vallée, Philippe Pierret, Guy Douce. Differences in host serotonin innervation of intrastriatal grafts are not determined by a glial scar or chondroitin sulfate proteoglycans. Experimental neurology. vol 177. issue 1. 2002-12-09. PMID:12429211. |
to test the hypothesis that differences in glial scarring or expression of the growth inhibitory molecules, chondroitin sulfate proteoglycans (cspg), be responsible for these differences in 5-ht innervation of neural grafts, we examined the 5-ht innervation, the astroglial reaction and the expression of cspg in ventral mesencephalic grafts implanted into newborn (1-5 days old), juvenile (15 days old), or adult rats and in striatal grafts implanted in adult rats, using immunohistochemistry against 5-ht, glial fibrillary acidic protein (gfap) and cspg. |
2002-12-09 |
2023-08-12 |
rat |
| Patricia Tagliaferro, Maita Duhalde Vega, Sergio Gustavo Evrard, Alberto Javier Ramos, Alicia Brusc. Alcohol exposure during adulthood induces neuronal and astroglial alterations in the hippocampal CA-1 area. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105109. |
the aim of the present work was to study the morphologic alterations of glial cells and neurons on the hippocampus after long-term etoh exposure using gfap and s-100 beta protein, neurofilaments of 200 kda (nf200), map2, and serotonin transporter (5ht-t) immunocytochemical staining. |
2002-08-02 |
2023-08-12 |
rat |
| Alberto Javier Ramos, Sergio Gustavo Evrard, Patricia Tagliaferro, María Victoria Tricárico, Alicia Brusc. Effects of chronic maternal ethanol exposure on hippocampal and striatal morphology in offspring. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105110. |
rat offspring brains were processed by immunocytochemistry using antibodies directed to gfap, serotonin transporter (5htt), or s-100 beta protein. |
2002-08-02 |
2023-08-12 |
rat |
| Alberto Javier Ramos, Sergio Gustavo Evrard, Patricia Tagliaferro, María Victoria Tricárico, Alicia Brusc. Effects of chronic maternal ethanol exposure on hippocampal and striatal morphology in offspring. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105110. |
cell area of gfap(+) astrocytes, surface of 5htt(+) fibers per area unit, and relative optical density (rod) of s-100 beta(+) astrocytes were measured and statistically processed. |
2002-08-02 |
2023-08-12 |
rat |
| Alberto Javier Ramos, Sergio Gustavo Evrard, Patricia Tagliaferro, María Victoria Tricárico, Alicia Brusc. Effects of chronic maternal ethanol exposure on hippocampal and striatal morphology in offspring. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105110. |
our results show that astroglial gfap was increased (astrocytes were hypertrophied) and 5htt(+) fibers were increased in both the hippocampal ca-1 area and the striatum. |
2002-08-02 |
2023-08-12 |
rat |
| K Yoshimoto, B Kato, S Ueda, K Noritake, K Sakai, M Shibata, M Hori, H Kawano, Y Takeuchi, Y Wakabayashi, M Yasuhar. Dopamine and serotonin uptake inhibitors on the release of dopamine and serotonin in the nucleus accumbens of young and aged rats. Mechanisms of ageing and development. vol 122. issue 15. 2001-12-07. PMID:11557275. |
analysis of da and 5-ht concentrations in the acc with increased positive gfap revealed that da and dopac levels of aged rats were decreased to 55 and 60% of those in young rats, respectively. |
2001-12-07 |
2023-08-12 |
rat |
| T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758340. |
the colocalization of 5ht(2a) receptors in astrocytes was performed by double-immunofluorescence staining of 5ht(2a) receptors and of glial fibrillary acidic protein (gfap) using confocal laser microscopy. |
2000-05-31 |
2023-08-12 |
rat |
| Z Cai, G P Schools, H K Kimelber. Metabotropic glutamate receptors in acutely isolated hippocampal astrocytes: developmental changes of mGluR5 mRNA and functional expression. Glia. vol 29. issue 1. 2000-01-18. PMID:10594924. |
we have found that 77% of gfap (+) cells from p11-20 rats responded to 50 microm glu, 43% to atp, and none to 5-ht. |
2000-01-18 |
2023-08-12 |
rat |
| Z Cai, G P Schools, H K Kimelber. Metabotropic glutamate receptors in acutely isolated hippocampal astrocytes: developmental changes of mGluR5 mRNA and functional expression. Glia. vol 29. issue 1. 2000-01-18. PMID:10594924. |
thirty-three percent of gfap (+) cells from p25-35 rats responded to glu, 12% to atp and 3% to 5-ht. |
2000-01-18 |
2023-08-12 |
rat |
| T M Walker, J E Davenport-Jones, R M Fox, C K Atterwil. The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture. Cell biology and toxicology. vol 15. issue 3. 1999-12-29. PMID:10580546. |
exposure of brain spheroids to mdma or the metabolite 6-oh mdma (up to 500 micromol/l) for 5 days in culture did not alter intracellular levels of glutathione (gsh), glial fibrillary acidic protein (gfap) or serotonin (5-ht). |
1999-12-29 |
2023-08-12 |
rat |
| T M Walker, J E Davenport-Jones, R M Fox, C K Atterwil. The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture. Cell biology and toxicology. vol 15. issue 3. 1999-12-29. PMID:10580546. |
there was also a significant reduction in the levels of glial fibrillary acidic protein (gfap) and gsh by dhma at the highest concentration tested (500 micromol/l) but there was no effect on 5ht. |
1999-12-29 |
2023-08-12 |
rat |
| C Wu, S K Singh, P Dias, S Kumar, D M Man. Activated astrocytes display increased 5-HT2a receptor expression in pathological states. Experimental neurology. vol 158. issue 2. 1999-08-24. PMID:10415157. |
such activated astrocytes display gfap and strong 5-ht(2a), but not 5-ht(2b) or 5-ht(2c), receptor immunoreactivity; this 5-ht(2a) reaction has not been observed in normal, nonactivated astrocytes. |
1999-08-24 |
2023-08-12 |
human |
| J M Brezun, A Daszut. Serotonin depletion in the adult rat produces differential changes in highly polysialylated form of neural cell adhesion molecule and tenascin-C immunoreactivity. Journal of neuroscience research. vol 55. issue 1. 1999-03-15. PMID:9890434. |
indeed, increases in glial fibrillary acidic protein (gfap) followed by increases in tn-c were observed in these areas, suggesting that the secretion of tn-c by astrocytes may have negative consequences on the sprouting of 5-ht fibers. |
1999-03-15 |
2023-08-12 |
rat |
| M Fukumura, G D Cappon, C Pu, H W Broening, C V Vorhee. A single dose model of methamphetamine-induced neurotoxicity in rats: effects on neostriatal monoamines and glial fibrillary acidic protein. Brain research. vol 806. issue 1. 1998-11-20. PMID:9739098. |
neostriatal da, 5-ht, th, and gfap were assayed 3 days following treatment. |
1998-11-20 |
2023-08-12 |
rat |
| M Fukumura, G D Cappon, C Pu, H W Broening, C V Vorhee. A single dose model of methamphetamine-induced neurotoxicity in rats: effects on neostriatal monoamines and glial fibrillary acidic protein. Brain research. vol 806. issue 1. 1998-11-20. PMID:9739098. |
ma induced dose-dependent reductions of da, 5-ht and th, and increased gfap. |
1998-11-20 |
2023-08-12 |
rat |
| F Fumagalli, R R Gainetdinov, K J Valenzano, M G Caro. Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 13. 1998-07-02. PMID:9634552. |
dopamine (da) and serotonin (5-ht) content, glial fibrillary acidic protein (gfap) expression, and free radical formation were assessed as markers of meth neurotoxicity in the striatum and/or hippocampus of wild-type, heterozygote, and homozygote (dat -/-) mice. |
1998-07-02 |
2023-08-12 |
mouse |
| R Franzen, J Schoenen, P Leprince, E Joosten, G Moonen, D Marti. Effects of macrophage transplantation in the injured adult rat spinal cord: a combined immunocytochemical and biochemical study. Journal of neuroscience research. vol 51. issue 3. 1998-03-31. PMID:9486767. |
at various survival times, we have studied their effect on the expression of neuronal (neurofilaments [nf], calcitonin gene-related peptide [cgrp], 5-hydroxytryptamine [5-ht]) and nonneuronal markers (myelin-associated glycoprotein [mag], glial fibrillary acidic protein [gfap], laminin) by using semiquantitative western blot and immunohistochemical techniques. |
1998-03-31 |
2023-08-12 |
rat |
| P Tagliaferro, A J Ramos, E M López, J Pecci Saavedra, A Brusc. Neural and astroglial effects of a chronic parachlorophenylalanine-induced serotonin synthesis inhibition. Molecular and chemical neuropathology. vol 32. issue 1-3. 1998-02-26. PMID:9437667. |
in a model of chronic inhibition of endogenous 5ht synthesis produced by the daily administration of parachlorophenylalanine (pcpa) for 2 wk, we have studied by immunohistochemical methods and digital morphometric analysis the expression of two proteins present in rat brain astrocytes: glial fibrillary acidic protein (gfap) and s-100 protein. |
1998-02-26 |
2023-08-12 |
rat |