| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F A Curro, S Greenberg, T J Verbeuren, P M Vanhoutt. Interaction between alpha adrenergic and serotonergic activation of canine saphenous veins. The Journal of pharmacology and experimental therapeutics. vol 207. issue 3. 1979-03-13. PMID:215746. |
these findings suggest that serotonin does not contract canine saphenous veins by stimulation of typical serotonergic receptors. |
1979-03-13 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
the hypothesis that morphine acts on the serotonergic system to produce analgesia is based on the previous observations that (1) lesions and stimulation of midbrain raphe nuclei after the threshold to nociceptive stimuli; (2) morphine alters the turnover of serotonin (5-hydroxytryptamine; 5-ht). |
1979-01-26 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
microiontophoretic experiments were carried out to determine if morphine affected the firing rate of cells in five areas of the serotonergic system consisting of 5-ht containing neurons in the midbrain raphe nuclei (dorsal raphe and median raphe) or neurons in three areas (amygdala, optic tectum and subiculum) which are thought to receive a 5-ht input from the raphe nuclei. |
1979-01-26 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
it is concluded that (1) the analgesic effect of morphine is not related to an effect on neurons in the midbrain raphe nuclei and three areas which receive an identified 5-ht input; and (2) the effect of morphine on neurons in these five areas of the serotonergic system is not a specific narcotic effect. |
1979-01-26 |
2023-08-11 |
Not clear |
| D J Goldberg, J H Schwartz, A A Sherban. Kinetic properties of normal and perturbed axonal transport of serotonin in a single identified axon. The Journal of physiology. vol 281. 1978-12-27. PMID:81302. |
the axonal transport of pulses of [3h]serotonin was studied in an axon of the serotonergic giant cerebral neurone (gcn) of aplysia californica. |
1978-12-27 |
2023-08-11 |
aplysia |
| M Ogaw. Interaction between noradrenergic and serotonergic mechanisms on the central regulation of blood pressure in the rat: a study using experimental central hypertension produced by chemical lesions of the locus coeruleus. Japanese circulation journal. vol 42. issue 5. 1978-12-27. PMID:151755. |
the results of these experiments demonstrate that (1) lc hypertension is probably due to a specific lesion of the lc with 6-ohda, (2) lc hypertension is accompanied by an increase of 5-ht turnover in the cortex and especially in the spinal cord, which may participate in a depressor function in lc hypertension, (3) ablation of bulbospinal serotonergic neurons produce mild elevation in blood pressure. |
1978-12-27 |
2023-08-11 |
rat |
| R F Martin, L M Jordan, W D Willi. Differential projections of cat medullary raphe neurons demonstrated by retrograde labelling following spinal cord lesions. The Journal of comparative neurology. vol 182. issue 1. 1978-12-27. PMID:701490. |
the serotonergic (5ht) fibers described by dahlström and fuxe ('65) to terminate in the dorsal horn, intermediolateral cell column, and ventral horn are likely to coincide with the raphe-spinal projections documented in this work. |
1978-12-27 |
2023-08-11 |
cat |
| R Bessone, L Segu, A Cala. Radioautographic identification of serotonergic neurones in Aplysia. Experientia. vol 34. issue 8. 1978-12-20. PMID:700018. |
radioautography shows that 3h 5-ht specifically labels metacerebral and 2 other serotonergic cell bodies in aplysia cerebroid ganglia as well as 5-ht terminals in close contact with giant neurone membrane in buccal ganglia. |
1978-12-20 |
2023-08-11 |
aplysia |
| J P Chalmers, L M Win. Central serotonergic neurons and experimental neurogenic and renal hypertension in the rabbit. Clinical science and molecular medicine. Supplement. vol 2. 1978-12-02. PMID:1077778. |
rabbits received intracisternal injections of 5,6-dihydroxytryptamine (5,6-dht) in order to ablate central serotonergic nerves and deplete central serotonin stores. |
1978-12-02 |
2023-08-11 |
rabbit |
| R B Rastogi, R L Singha. The effect of thyroid hormone on serotonergic neurones: depletion of serotonin in discrete brain areas of developing hypothyroid rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 1. 1978-11-29. PMID:692746. |
the effect of thyroid hormone on serotonergic neurones: depletion of serotonin in discrete brain areas of developing hypothyroid rats. |
1978-11-29 |
2023-08-11 |
rat |
| S K Bhattacharya, P R Keshary, A K Sanya. Immobilisation stress-induced antinociception in rats: possible role of serotonin and prostaglandins. European journal of pharmacology. vol 50. issue 1. 1978-10-18. PMID:150334. |
antinociception induced by 4 h immobilisation was significantly inhibited after pretreatment by drugs known to inhibit synthesis of serotonin, induce degeneration of serotonergic neurones and inhibit prostaglandin synthesis. |
1978-10-18 |
2023-08-11 |
rat |
| J S Meyer, N S Buckholtz, W O Bogga. Serotonergic stimulation of pituitary-adrenal activity in the mouse. Neuroendocrinology. vol 26. issue 5. 1978-10-18. PMID:150549. |
it is concluded that (1) 5-htp stimulates pituitary-adrenal activity in mice by being converted to 5-ht and acting on 1 or more groups of serotonergic receptors; (2) these receptors are located either in an area of the brain outside of the blood-brain barrier such as the median eminence or in a peripheral tissue(s); (3) tryptophan-derived 5-ht can stimulate these receptors, but only if allowed to accumulate by inhibiting its catabolism; and (4) it is not yet clear whether pituitary-adrenal responses to quipazine and 6-meo-thbc are mediated by a serotonergic mechanism. |
1978-10-18 |
2023-08-11 |
mouse |
| G S Omenn, L T Smit. A common uptake system for serotonin and dopamine in human platelets. The Journal of clinical investigation. vol 62. issue 2. 1978-09-15. PMID:670392. |
uptake of serotonin into platelets closely resembles reuptake of serotonin into serotonergic neurons. |
1978-09-15 |
2023-08-11 |
human |
| J D Lane, M H Apriso. The flux of radioactive label through components of the serotonergic system following the injection of [3H]tryptophan: product--precursor anomalies providing evidence that serotonin exists in multiple pools. Journal of neurochemistry. vol 30. issue 4. 1978-07-26. PMID:650211. |
the flux of radioactive label through components of the serotonergic system following the injection of [3h]tryptophan: product--precursor anomalies providing evidence that serotonin exists in multiple pools. |
1978-07-26 |
2023-08-11 |
Not clear |
| C J Helke, J A Quest, R A Gilli. Effects of serotonin antagonists on digitalis-induced ventricular arrhythmias. European journal of pharmacology. vol 47. issue 4. 1978-05-24. PMID:147176. |
these data indicate that serotonin antagonists are effective in counteracting digitalis-induced ventricular arrhythmias and support the notion that a serotonergic mechanism may be mediating the arrhythmogenic effect of digitalis. |
1978-05-24 |
2023-08-11 |
Not clear |
| S M Stahl, H Y Meltze. A kinetic and pharmacologic analysis of 5-hydroxytryptamine transport by human platelets and platelet storage granules: comparison with central serotonergic neurons. The Journal of pharmacology and experimental therapeutics. vol 205. issue 1. 1978-05-24. PMID:633077. |
a kinetic and pharmacologic analysis of 5-hydroxytryptamine transport by human platelets and platelet storage granules: comparison with central serotonergic neurons. |
1978-05-24 |
2023-08-11 |
human |
| J J Clancy, D F Caldwell, D Oberleas, S Sangiah, M J Villeneuv. Effect of a chronic tryptophan dietary deficiency on the rat's sleep-wake cycle. Brain research bulletin. vol 3. issue 1. 1978-05-08. PMID:204399. |
the results do not support the suggested relationship between reduced serotonin levels and the occurrence of insomnia, questioning the serotonergic theory of sleep. |
1978-05-08 |
2023-08-11 |
rat |
| D Tsang, S La. Effect of monoamine receptor agonists and antagonists on cyclic AMP accumulation in human cerebral cortex slices. Canadian journal of physiology and pharmacology. vol 55. issue 6. 1978-03-29. PMID:23211. |
chlorpromazine blocked the increase of cyclic amp formation induced by noradrenaline, dopamine or serotonin, while cyproheptadine, a putative central serotonergic antagonist, was ineffective. |
1978-03-29 |
2023-08-11 |
human |
| A H Dickenso. Specific responses of rat raphé neurones to skin temperature. The Journal of physiology. vol 273. issue 1. 1978-03-10. PMID:599422. |
the results suggest that any involvement of 5-ht in central thermo-regulation is in terms of an afferent thermal pathway mediated by serotonergic raphé neurones. |
1978-03-10 |
2023-08-11 |
rat |
| J E Goldman, J H Schwart. Metabolism of [3H]serotonin in the marine mollusc, Aplysia californica. Brain research. vol 136. issue 1. 1978-02-18. PMID:589448. |
when [3h]serotonin was injected directly into cell bodies of identified neurons, both serotonergic and non-serotonergic, only the conjugate which behaved as the glucuronide was formed. |
1978-02-18 |
2023-08-11 |
aplysia |