| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
to direct outgrowth, serotonergic neurons utilize serotonin as a signaling molecule prior to it assuming its neurotransmitter role. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
this process, termed serotonin autoregulation, regulates axon outgrowth, branching, and varicosity development of serotonergic neurons. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
using cultured drosophila serotonergic neurons, we found that exogenous serotonin reduced axon length and branching only in those expressing 5-ht1a. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
altogether this suggests that 5-ht1a is a serotonin autoreceptor in a subpopulation of serotonergic neurons and initiates signaling pathways that regulate axon outgrowth and branching during drosophila development. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Mauro Chivite, Rosa M Ceinos, José M Cerdá-Reverter, Jose L Soengas, Manuel Aldegunde, Marcos A López-Patiño, Jesús M Mígue. Unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow trout Frontiers in endocrinology. vol 14. 2023-09-11. PMID:37693350. |
unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow trout this study explored changes in brain serotonin content and activity together with hypothalamic neuropeptide mrna abundance around feeding time in rainbow trout, as well as the effect of one-day fasting. |
2023-09-11 |
2023-10-07 |
Not clear |
| Xue Chen, Jing Li, Lisa Yu, Francesca Maule, Limei Chang, Jonathan Gallant, David J Press, Sheetal A Raithatha, Jillian M Hagel, Peter J Facchin. A cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic amines. The Journal of biological chemistry. 2023-09-10. PMID:37690691. |
since the therapeutic potential of psychedelics has been linked to activity at serotonergic receptors, we evaluated binding of derivatives at 5-ht |
2023-09-10 |
2023-10-07 |
Not clear |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
we also demonstrate that the 5-ht dysfunction is caused by smn deficiency in serotonergic neurons in the raphe nuclei of the brainstem. |
2023-09-07 |
2023-10-07 |
mouse |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
the behavioural significance of the dysfunction in serotonergic neuromodulation is underlined by inter-limb discoordination in sma mice, which is ameliorated when selective restoration of smn in 5-ht neurons is achieved by genetic means. |
2023-09-07 |
2023-10-07 |
mouse |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
our study uncovers an unexpected dysfunction of serotonergic neuromodulation in sma and indicates that, if normal function is to be restored under disease conditions, 5-ht neuromodulation should be a key target for therapeutic approaches. |
2023-09-07 |
2023-10-07 |
mouse |
| Christopher R Brown, James D Foste. Palmitoylation Regulates Human Serotonin Transporter Activity, Trafficking, and Expression and Is Modulated by Escitalopram. ACS chemical neuroscience. 2023-08-30. PMID:37644775. |
during serotonergic transmission, the synaptic concentration of serotonin is tightly controlled in a spatial and temporal manner by the serotonin transporter (sert). |
2023-08-30 |
2023-09-07 |
human |
| Sarah Chaib, Benjamin Vidal, Caroline Bouillot, Ronan Depoortere, Adrian Newman-Tancredi, Luc Zimmer, Elise Levigoureu. Multimodal imaging study of the 5-HT NeuroImage. Clinical. vol 39. 2023-08-26. PMID:37632990. |
serotonergic neurons are involved in lid etiology and previous pre-clinical studies have shown that nlx-112, a 5-ht |
2023-08-26 |
2023-09-07 |
Not clear |
| Margot De Kooning, Iris Coppieters, Eva Huysmans, Jo Nijs, Mira Meeus, Lennard Voogt, Erwin Hendriks, Kelly Ickman. Unravelling Impaired Hypoalgesia at Rest and in Response to Exercise in Patients with Chronic Whiplash-Associated Disorders: Effects of a Single Administration of Selective Serotonin Reuptake Inhibitor versus Selective Norepinephrine Reuptake Inhibitor. Journal of clinical medicine. vol 12. issue 15. 2023-08-12. PMID:37568380. |
therefore, this study aimed to examine the isolated effect of activating serotonergic or noradrenergic descending pathways on hypoalgesia at rest and in response to exercise in patients with chronic wad by using respectively a single dose of a selective serotonin reuptake inhibitor (ssri) and a selective norepinephrine reuptake inhibitor (nri). |
2023-08-12 |
2023-08-16 |
human |
| Kristine Conde, Shuzheng Fang, Yong X. Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review. Cell & bioscience. vol 13. issue 1. 2023-08-07. PMID:37550777. |
this review focuses on the history of serotonin, the state of current central serotonin research, previous serotonergic therapies, and the future of serotonin for treating individuals with obesity. |
2023-08-07 |
2023-08-14 |
Not clear |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
the success of using selective serotonin reuptake inhibitors (ssris) to treat these two disorders highlights the involvement of the central serotonergic (5-ht) system. |
2023-08-06 |
2023-08-14 |
rat |
| Yurim Shin, Seungjik Kim, Jong-Woo Soh. Serotonergic regulation of appetite and sodium appetite. Journal of neuroendocrinology. 2023-08-01. PMID:37525500. |
it is well known that the activity of raphe serotonergic neurons is changed in response to the changes in feeding status to regulate appetite via the serotonin receptors. |
2023-08-01 |
2023-08-14 |
Not clear |
| Yurim Shin, Seungjik Kim, Jong-Woo Soh. Serotonergic regulation of appetite and sodium appetite. Journal of neuroendocrinology. 2023-08-01. PMID:37525500. |
likewise, changes in volume status are known to alter the activity of raphe serotonergic neurons and drugs targeting serotonin receptors were shown to affect sodium appetite. |
2023-08-01 |
2023-08-14 |
Not clear |
| Can Tao, Guang-Wei Zhang, Junxiang J Huang, Zhong Li, Huizhong W Tao, Li I Zhan. The medial preoptic area mediates depressive-like behaviors induced by ovarian hormone withdrawal through distinct GABAergic projections. Nature neuroscience. 2023-07-31. PMID:37524978. |
these projections enhance activity of dopaminergic neurons in the vta and serotonergic neurons in the dorsal raphe, respectively, with increased release of dopamine and serotonin, possibly through disinhibition mechanisms. |
2023-07-31 |
2023-08-14 |
mouse |
| Abimael González-Hernández, Bruno A Marichal-Cancino, Antoinette MaassenVanDenBrink, Carlos M Villaló. Serotonergic Modulation of Neurovascular Transmission: A Focus on Prejunctional 5-HT Receptors/Mechanisms. Biomedicines. vol 11. issue 7. 2023-07-29. PMID:37509503. |
serotonergic modulation of neurovascular transmission: a focus on prejunctional 5-ht receptors/mechanisms. |
2023-07-29 |
2023-08-14 |
Not clear |
| Nazarine Mokhtar, Stephane Doly, Christine Courtei. Diabetic Neuropathic Pain and Serotonin: What Is New in the Last 15 Years? Biomedicines. vol 11. issue 7. 2023-07-29. PMID:37509563. |
in this review, we report data from preclinical work published over the last 15 years on the analgesic activity of drugs acting on the serotonergic system, such as serotonin and noradrenaline reuptake inhibitor (snri) antidepressants, and on the involvement of certain serotonin receptors-in particular 5-ht |
2023-07-29 |
2023-08-14 |
Not clear |
| Liumin Li, Qu M. Serotonin Syndrome From Duloxetine Monotherapy: A Case Report. Cureus. vol 15. issue 6. 2023-07-27. PMID:37496538. |
serotonin syndrome is a rare adverse reaction induced by serotonergic drugs. |
2023-07-27 |
2023-08-14 |
Not clear |