| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuma Nagai, Yuri Kisaka, Kento Nomura, Naoya Nishitani, Chihiro Andoh, Masashi Koda, Hiroyuki Kawai, Kaoru Seiriki, Kazuki Nagayasu, Atsushi Kasai, Hisashi Shirakawa, Takanobu Nakazawa, Hitoshi Hashimoto, Shuji Kanek. Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience. Cell reports. vol 42. issue 3. 2023-02-23. PMID:36821440. |
serotonergic (5-ht) neurons are central to the pathophysiology and treatment of mdd. |
2023-02-23 |
2023-08-14 |
Not clear |
| Benjamin I Goodlich, Alessandro Del Vecchio, Sean A Horan, Justin J Kavanag. Blockade of 5-HT The Journal of physiology. 2023-02-15. PMID:36790076. |
blockade of 5-ht serotonergic neuromodulation contributes to enhanced voluntary muscle activation. |
2023-02-15 |
2023-08-14 |
Not clear |
| Alyssa M West, Katherine M Holleran, Sara R Jone. Kappa Opioid Receptors Reduce Serotonin Uptake and Escitalopram Efficacy in the Mouse Substantia Nigra Pars Reticulata. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768403. |
it receives the densest serotonergic innervation in the brain and has high kor expression; however, the influence of kors on serotonin transmission in this region is yet to be explored. |
2023-02-11 |
2023-08-14 |
mouse |
| Prithvi Hemanth, Pallavi Nistala, Vy T Nguyen, Jose M Eltit, Richard A Glennon, Małgorzata Duka. Binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-HT Frontiers in pharmacology. vol 14. 2023-02-10. PMID:36762110. |
binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-ht certain 4-substituted analogs of 1-(2,5-dimethoxyphenyl)isopropylamine (2,5-dma) are psychoactive classical hallucinogens or serotonergic psychedelic agents that function as human 5-ht |
2023-02-10 |
2023-08-14 |
human |
| Eunchong Hong, Hyun Kyu Min, Heena Lim, Sun Mi Gu, Abdulaziz Jabborov, Taddesse Yayeh, Mijin Kim, Woo-Kyu Park, Jae-Chul Jung, Jaesuk Yun, Seikwan O. Derivatives of 3, 4, 5-Trimethoxycinnamic Acid Ameliorate Stress-Induced Anxiety in Mice and Rats. Molecular neurobiology. 2023-01-30. PMID:36715919. |
given the preferential inhibitory activity of dtmca on dopamine and serotonin receptors, serotonergic road map of cellular signaling could be their target for anxiolytic effects. |
2023-01-30 |
2023-08-14 |
mouse |
| Yong Soo Park, Haejung Oh, Ki-Wug Sun. Atypical antidepressant mirtazapine inhibits 5-hydroxytryptamine3 receptor currents in NCB-20 cells. Journal of pharmacological sciences. vol 151. issue 2. 2023-01-27. PMID:36707180. |
mirtazapine, an atypical antidepressant, is known to enhance serotonergic transmission by inhibiting the 5-hydroxytryptamine (5-ht) |
2023-01-27 |
2023-08-14 |
Not clear |
| Amy Cheung, Kotaro Konno, Yuka Imamura, Aya Matsui, Manabu Abe, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Masahiko Watanabe, Kensuke Futa. Neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors. eLife. vol 12. 2023-01-25. PMID:36695811. |
neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors. |
2023-01-25 |
2023-08-14 |
mouse |
| Swetha B M Gowda, Ayesha Banu, Safa Salim, Kadir A Peker, Farhan Mohamma. Serotonin distinctly controls behavioral states in restrained and freely moving iScience. vol 26. issue 1. 2023-01-19. PMID:36654863. |
we used optogenetics and intersectional genetic approaches to show that, while broader serotonin activation promotes immobility, serotonergic cells in the ventral nerve cord (vnc) regulate immobility states majorly via 5-ht7 receptors. |
2023-01-19 |
2023-08-14 |
Not clear |
| Gabriel Manjarrez-Gutiérrez, Guillermo Valero-Elizondo, Yesenia Serrano-Hernández, José Antonio Mondragón-Herrera, Armando Mansilla-Olivare. Hypertrophic cardiomyopathy induces changes in the tryptophan-5-hydroxylase, serotonin transporter and serotonergic receptors expressions. Gaceta medica de Mexico. vol 158. issue 6. 2023-01-19. PMID:36657118. |
hypertrophic cardiomyopathy induces changes in the tryptophan-5-hydroxylase, serotonin transporter and serotonergic receptors expressions. |
2023-01-19 |
2023-08-14 |
Not clear |
| David Erritzoe, Beata R Godlewska, Gaia Rizzo, Graham E Searle, Claudio Agnorelli, Yvonne Lewis, Abhishekh H Ashok, Alessandro Colasanti, Iro Boura, Chloe Farrell, Hollie Parfitt, Oliver Howes, Jan Passchier, Roger N Gunn, Marios Politis, David J Nutt, Philip J Cowen, Gitte M Knudsen, Eugenii A Rabine. Brain Serotonin Release Is Reduced in Patients With Depression: A [ Biological psychiatry. 2023-01-12. PMID:36635177. |
brain serotonin release is reduced in patients with depression: a [ the serotonin hypothesis of depression proposes that diminished serotonergic (5-ht) neurotransmission is causal in the pathophysiology of the disorder. |
2023-01-12 |
2023-08-14 |
Not clear |
| Nawal A Yahya, Janelle K Lanham, Daniel J Sprague, Oleg Palygin, John D McCorvy, Jonathan S Marchan. Molecular and cellular basis of praziquantel action in the cardiovascular system. American journal of physiology. Cell physiology. 2023-01-09. PMID:36622066. |
the contractile action of pzq on the vasculature is mediated by activation of host serotonergic 5-ht |
2023-01-09 |
2023-08-14 |
Not clear |
| Małgorzata Zawadzka, Marine Yeghiazaryan, Sylwia Niedziółka, Krzysztof Miazga, Anna Kwaśniewska, Marek Bekisz, Urszula Sławińsk. Forced Remyelination Promotes Axon Regeneration in a Rat Model of Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613945. |
behavioral tests performed at 60-90 dpi revealed significant improvement in locomotor function recovery in double-eb-injected rats, which was impaired by the blockade of serotonin receptors, confirming the important role of restored serotonergic fibers in functional recovery. |
2023-01-08 |
2023-08-14 |
rat |
| Jyotshna Kanungo, Nathan C Twaddle, Camila Silva, Bonnie Robinson, Mesay Wolle, Sean Conklin, Shaun MacMahon, Qiang Gu, Ian Edhlund, Linda Benjamin, Frederick A Beland, Suzanne C Fitzpatric. Inorganic arsenic alters the development of dopaminergic neurons but not serotonergic neurons and induces motor neuron development via Sonic hedgehog pathway in zebrafish. Neuroscience letters. 2023-01-01. PMID:36587726. |
while 200 mg/l sodium arsenite induced development of tyrosine hydroxylase-positive (dopaminergic) neurons; there was no significant effect on the development of 5-hydroxytryptamine (serotonergic) neurons. |
2023-01-01 |
2023-08-14 |
zebrafish |
| Jasmine D S Reggiani, Qiufen Jiang, Melanie Barbini, Andrew Lutas, Liang Liang, Jesseba Fernando, Fei Deng, Jinxia Wan, Yulong Li, Chinfei Chen, Mark L Anderman. Brainstem serotonin neurons selectively gate retinal information flow to thalamus. Neuron. 2022-12-30. PMID:36584680. |
converging evidence suggests that differential expression of the 5-ht1b receptor on rgc presynaptic terminals, but not differential density of nearby serotonin axons, may contribute to the selective serotonergic gating of specific visual information streams before they can activate thalamocortical neurons. |
2022-12-30 |
2023-08-14 |
mouse |
| Hiroyuki Kawai, Youcef Bouchekioua, Naoya Nishitani, Kazuhei Niitani, Shoma Izumi, Hinako Morishita, Chihiro Andoh, Yuma Nagai, Masashi Koda, Masako Hagiwara, Koji Toda, Hisashi Shirakawa, Kazuki Nagayasu, Yu Ohmura, Makoto Kondo, Katsuyuki Kaneda, Mitsuhiro Yoshioka, Shuji Kanek. Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion. Nature communications. vol 13. issue 1. 2022-12-22. PMID:36550097. |
although a critical role of serotonergic neurons in the dorsal raphe nucleus (drn) in reward processing has been shown, the lack of rewarding effects with selective serotonin reuptake inhibitors (ssris) implies the presence of a discrete serotonergic system playing an opposite role to the drn in the processing of reward and aversive stimuli. |
2022-12-22 |
2023-08-14 |
mouse |
| Hiroyuki Kawai, Youcef Bouchekioua, Naoya Nishitani, Kazuhei Niitani, Shoma Izumi, Hinako Morishita, Chihiro Andoh, Yuma Nagai, Masashi Koda, Masako Hagiwara, Koji Toda, Hisashi Shirakawa, Kazuki Nagayasu, Yu Ohmura, Makoto Kondo, Katsuyuki Kaneda, Mitsuhiro Yoshioka, Shuji Kanek. Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion. Nature communications. vol 13. issue 1. 2022-12-22. PMID:36550097. |
we further identified mrn serotonergic neurons, including those projecting to the interpeduncular nucleus (5-ht |
2022-12-22 |
2023-08-14 |
mouse |
| Brianna F Roberts, Alexia L Zylko, Courtney E Waters, Jessica D Crowder, William J Gibbons, Abhishek K Sen, J Andrew Jones, Matthew S McMurra. Effect of psilocybin on decision-making and motivation in the healthy rat. Behavioural brain research. 2022-12-18. PMID:36529299. |
psilocybin and its active metabolite psilocin are hallucinogenic serotonergic agonists with high affinity for several serotonin receptors. |
2022-12-18 |
2023-08-14 |
human |
| Carlos Aparecido da Silva Junior, Danuzia A Marques, Luís Gustavo A Patrone, Vivian Biancardi, Kênia C Bícego, Luciane H Gargaglion. Intra-uterine diazepam exposure decreases the number of catecholaminergic and serotoninergic neurons of neonate rats. Neuroscience letters. 2022-12-15. PMID:36521643. |
thus, we sought to evaluate the effects of intrauterine exposure to dzp on the number of brainstem's catecholaminergic and serotonergic neurons, implicated in respiratory control, in male and female rats on postnatal (p) day 12-13, using immunofluorescence labeling for tyrosine-hydroxylase (th) and serotonin (5-ht). |
2022-12-15 |
2023-08-14 |
rat |
| Valeria Buzzelli, Emilia Carbone, Antonia Manduca, Sara Schiavi, Alessandro Feo, Julia V Perederiy, Kyle H Ambert, Marvin Hausman, Viviana Trezz. Psilocybin mitigates the cognitive deficits observed in a rat model of Fragile X syndrome. Psychopharmacology. 2022-12-05. PMID:36469097. |
as serotonin is involved in synaptic remodeling and maturation, serotonergic insufficiency during childhood may have a compounding effect on brain patterning in neurodevelopmental disorders, manifesting as behavioral and emotional symptoms. |
2022-12-05 |
2023-08-14 |
rat |
| Rita Bardon. Serotonergic 5-HT 7 Receptors as Modulators of the Nociceptive System. Current neuropharmacology. 2022-12-01. PMID:36453491. |
serotonergic 5-ht 7 receptors as modulators of the nociceptive system. |
2022-12-01 |
2023-08-14 |
Not clear |