| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wesley D Kufel, Katie A Parsels, Bruce E Blaine, Jeffrey M Steele, Robert W Seabury, Elizabeth A Asiago-Redd. Real-world evaluation of linezolid-associated serotonin toxicity with and without concurrent serotonergic agents. International journal of antimicrobial agents. 2023-05-09. PMID:37160238. |
we sought to evaluate the incidence of serotonin toxicity among hospitalized patients who received linezolid with or without concurrent serotonergic agents (sa). |
2023-05-09 |
2023-08-14 |
Not clear |
| Fawzy Elbarbry, Nicholas Moshiria. Linezolid-associated serotonin toxicity: a systematic review. European journal of clinical pharmacology. 2023-05-02. PMID:37129603. |
this systematic review aims to evaluate the existing evidence associating linezolid to serotonin toxicity when used as monotherapy or when co-administered with other serotonergic agents. |
2023-05-02 |
2023-08-14 |
Not clear |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
the midbrain raphe serotonin (5ht) neurons provide the main ascending serotonergic projection to the forebrain, including hippocampus, which has a role in the pathophysiology of depressive disorder. |
2023-04-28 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
serotonin 5ht1a receptor (r) activation at the soma-dendritic level of serotonergic raphe neurons and glutamatergic hippocampal pyramidal neurons leads to a decrease in neuronal firing by activation of g protein-coupled inwardly-rectifying potassium (girk) channels. |
2023-04-28 |
2023-08-14 |
rat |
| Thi Mai Loan Nguyen, Fabrice Jollant, Laurent Tritschler, Romain Colle, Emmanuelle Corruble, Alain M Gardie. Pharmacological Mechanism of Ketamine in Suicidal Behavior Based on Animal Models of Aggressiveness and Impulsivity: A Narrative Review. Pharmaceuticals (Basel, Switzerland). vol 16. issue 4. 2023-04-28. PMID:37111391. |
the present review focuses on disruptions in the serotonergic system (5-ht |
2023-04-28 |
2023-08-14 |
Not clear |
| Kana Harada, Ryoma Sho, Hiromiki Takakura, Eri Yokoyama, Reika Koyama, Yuka Yamamoto, Naoko Adachi, Shigeru Tanaka, Izumi Hide, Norio Saka. S-Palmitoylation of the serotonin transporter promotes its cell surface expression and serotonin uptake. Biochemical and biophysical research communications. vol 662. 2023-04-26. PMID:37099811. |
the neurotransmitter serotonin (5-ht) is transported back into serotonergic neurons by the serotonin transporter (sert). |
2023-04-26 |
2023-08-14 |
human |
| Hannah P Fricke, Laura L Hernande. The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad. Journal of mammary gland biology and neoplasia. vol 28. issue 1. 2023-04-22. PMID:37086330. |
this review will focus on the relationship between the mammary gland, serotonin, and bone remodeling during the peripartal period and the skeletal consequences of the dysregulation of the serotonergic system in both human and animal studies. |
2023-04-22 |
2023-08-14 |
human |
| Ashlea A Morgan, Nuno D Alves, Gregory S Stevens, Tamanna T Yeasmin, Alexandra Mackay, Saige Power, Derya Sargin, Carla Hanna, Arwa L Adib, Annette Ziolkowski-Blake, Evelyn K Lambe, Mark S Ansorg. Medial Prefrontal Cortex Serotonin Input Regulates Cognitive Flexibility in Mice. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034804. |
neurons that release serotonin project to the mpfc, and serotonergic drugs influence emotion and cognition. |
2023-04-10 |
2023-08-14 |
mouse |
| Kanza M Khan, Nagalakshmi Balasubramanian, Gabriel Gaudencio, Ruixiang Wang, Govindhasamy Pushpavathi Selvakumar, Louis Kolling, Samantha Pierson, Satya M Tadinada, Ted Abel, Marco Hefti, Catherine A Marcinkiewc. Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease. Acta neuropathologica communications. vol 11. issue 1. 2023-04-03. PMID:37009893. |
the behavioral changes at 4 months coincided with a lower density of serotonergic (5-ht) neurons, downregulation of 5-ht markers, reduced excitability of 5-ht neurons, and hyperphosphorylated tau in the drn. |
2023-04-03 |
2023-08-14 |
mouse |
| M E Flanigan, O J Hon, S D'Ambrosio, K M Boyt, L Hassanein, M Castle, H L Haun, M M Pina, T L Kas. Subcortical serotonin 5HT Nature communications. vol 14. issue 1. 2023-03-31. PMID:37002196. |
these negative behavioral outcomes were associated with sex-specific adaptations in serotonergic signaling systems within the lateral habenula (lhb) and the bed nucleus of the stria terminalis (bnst), particularly those related to the receptor 5ht |
2023-03-31 |
2023-08-14 |
mouse |
| Jenna Essakow, Lulu Jin, Neelima Marupudi, Rachel Wattier, Patrick McQuillen, Deborah Franzo. Serotonin Syndrome in an Infant Associated With Linezolid and Opioid Use. The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG. vol 27. issue 6. 2023-03-29. PMID:36988981. |
most reported cases of serotonin syndrome involve either a selective serotonin reuptake inhibitor (ssri) or monoamine oxidase inhibitors (maoi) and at least 1 other serotonergic medication or exposure to a single serotonin-augmenting drug. |
2023-03-29 |
2023-08-14 |
Not clear |
| Hyunji Cho, Miyea Jo, Haemin Oh, Yunjung Lee, Yongsoon Par. Synergistic antidepressant-like effect of n-3 polyunsaturated fatty acids and probiotics through the brain-gut axis in rats exposed to chronic mild stress. The Journal of nutritional biochemistry. 2023-03-24. PMID:36963732. |
n-3 pufa and probiotics upregulated the brain serotonergic pathway through serotonin levels and expression of brain-derived neurotrophic factor, phosphorylated camp response binding protein, and 5-hydroxytryptamine 1a receptor while downregulating the gut serotonergic pathway. |
2023-03-24 |
2023-08-14 |
rat |
| Ashwini Biradar, C B Ganes. Serotonin-immunoreactivity in the brain of the cichlid fish Oreochromis mossambicus. Anatomical record (Hoboken, N.J. : 2007). 2023-03-20. PMID:36938774. |
while the presence of 5-ht-ir cells and fibers in gustatory centers suggests a role for serotonin in the processing of gustatory signals, distinctive pattern of 5-ht immunoreactivity was seen in the telencephalon, pretectal areas, mesencephalic, and rhombencephalic regions, suggesting a cichlid fish specific organization of the serotonergic system. |
2023-03-20 |
2023-08-14 |
Not clear |
| Raquel Pereira-Silva, Paula Serrão, Fani Lourença Neto, Isabel Martin. Diffuse noxious inhibitory controls in chronic joint inflammatory Pain: Study of the descending serotonergic modulation mediated through 5HT3 receptors. Neurobiology of pain (Cambridge, Mass.). vol 13. 2023-03-14. PMID:36915290. |
here, we aimed at studying dnic in monoarthritis (ma) by exploring the spinal component of the descending serotonergic system, specifically 5-hydroxytryptamine 3 receptors (5-ht3r). |
2023-03-14 |
2023-08-14 |
rat |
| Raquel Pereira-Silva, Paula Serrão, Fani Lourença Neto, Isabel Martin. Diffuse noxious inhibitory controls in chronic joint inflammatory Pain: Study of the descending serotonergic modulation mediated through 5HT3 receptors. Neurobiology of pain (Cambridge, Mass.). vol 13. 2023-03-14. PMID:36915290. |
at this later timepoint, ma rats showed increased: (i) spinal 5-ht3r and 5-ht levels, (ii) neuronal serotonergic activation and tph expression at the rvm. |
2023-03-14 |
2023-08-14 |
rat |
| Elena López-Terrones, Verónica Paz, Leticia Campa, Sara Conde-Berriozabal, Mercè Masana, Francesc Artigas, Maurizio S Rig. Differential Modulation of Dorsal Raphe Serotonergic Activity in Rat Brain by the Infralimbic and Prelimbic Cortices. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902322. |
boosting excitatory neurotransmission in the il-but not in the prelimbic cortex, prl-evokes depressive-like or antidepressant-like behaviors in rodents, which are associated with changes in serotonergic (5-ht) neurotransmission. |
2023-03-11 |
2023-08-14 |
rat |
| Renata Matraszek-Gawron, Mirosława Chwil, Karol Terlecki, Michał Marian Skoczyla. Current Knowledge of the Antidepressant Activity of Chemical Compounds from Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-03-08. PMID:36678554. |
this systematic review on antidepressant compounds in saffron crocus and their mechanisms of action and side effects is based on publications released between 1995−2022 and data indexed in 15 databases under the following search terms: antidepressant effect, central nervous system, crocus sativus, cognitive impairement, crocin, crocetin, depression, dopamine, dopaminergic and serotonergic systems, picrocrocin, phytotherapy, neurotransmitters, safranal, saffron, serotonin, and biologically active compounds. |
2023-03-08 |
2023-08-16 |
Not clear |
| Alireza Noori, Kousha Farhadi, Yasmin Mohtasham Kia, Nastaran Hosseini, Soraya Mehrab. Role of P11 through serotonergic and glutamatergic pathways in LID. Molecular biology reports. 2023-02-28. PMID:36853472. |
studies showed that metabotropic glutamate receptor 5 (mglur5) antagonists and 5-hydroxytryptamine receptor 1b (5ht1b) agonists significantly reduced lid when considering the glutamatergic overactivity and compensatory mechanisms of serotonergic neurons after l-dopa therapy. |
2023-02-28 |
2023-08-14 |
Not clear |
| Lluis Miquel-Rio, Unai Sarriés-Serrano, Rubén Pavia-Collado, J Javier Meana, Analia Bortolozz. The Role of α-Synuclein in the Regulation of Serotonin System: Physiological and Pathological Features. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831077. |
indeed, dysfunction of the serotonergic (5-ht) system, which regulates mood and emotional pathways, occurs during the premotor phase of pd. |
2023-02-25 |
2023-08-14 |
Not clear |
| Alexandra J Ng, Lindsay K Vincelette, Jiayi Li, Bridget H Brady, John P Christianso. Serotonin modulates social responses to stressed conspecifics via insular 5-HT bioRxiv : the preprint server for biology. 2023-02-24. PMID:36824837. |
we hypothesized that social reactions to stressed individuals engage the serotonergic dorsal raphe nucleus (drn) which promotes anxiety-like behavior via postsynaptic action of serotonin at serotonin 2c (5-ht |
2023-02-24 |
2023-08-14 |
Not clear |