| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshitaka Kumakura, Erik H Danielsen, Albert Gjedde, Ingo Vernaleken, Hans-Georg Buchholz, Andreas Heinz, Gerhard Gründer, Peter Bartenstein, Paul Cummin. Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson's disease. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941962. |
increased fdopa trapping in the periaqueductal grey of pd patients seems consistent with recent reports of increased activity of serotonin neurons in a rat model of parkinsonism. |
2010-04-26 |
2023-08-12 |
rat |
| Janaina M Zanoveli, Milene C Carvalho, Joice M Cunha, Marcus L Brandã. Extracellular serotonin level in the basolateral nucleus of the amygdala and dorsal periaqueductal gray under unconditioned and conditioned fear states: an in vivo microdialysis study. Brain research. vol 1294. 2010-01-12. PMID:19646971. |
extracellular serotonin level in the basolateral nucleus of the amygdala and dorsal periaqueductal gray under unconditioned and conditioned fear states: an in vivo microdialysis study. |
2010-01-12 |
2023-08-12 |
Not clear |
| Daniel Campos Villela, Luiz Gonzaga da Silva, Marco Antônio Peliky Fonte. Activation of 5-HT receptors in the periaqueductal gray attenuates the tachycardia evoked from dorsomedial hypothalamus. Autonomic neuroscience : basic & clinical. vol 148. issue 1-2. 2009-07-23. PMID:19303372. |
activation of 5-ht receptors in the periaqueductal gray attenuates the tachycardia evoked from dorsomedial hypothalamus. |
2009-07-23 |
2023-08-12 |
rat |
| Frederico G Graeff, Cristina M Del-Be. Neurobiology of panic disorder: from animal models to brain neuroimaging. Neuroscience and biobehavioral reviews. vol 32. issue 7. 2009-02-19. PMID:18573531. |
evidence from animal models of anxiety has led to the hypothesis that serotonin enhances inhibitory avoidance (related to anxiety) in the forebrain, but inhibits one-way escape (panic) in the midbrain periaqueductal gray (pag). |
2009-02-19 |
2023-08-12 |
rat |
| Cladis L K Moraes, Leandro J Bertoglio, Antonio P Carobre. Interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze. Behavioural brain research. vol 194. issue 2. 2009-02-03. PMID:18675851. |
interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze. |
2009-02-03 |
2023-08-12 |
rat |
| Cladis L K Moraes, Leandro J Bertoglio, Antonio P Carobre. Interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze. Behavioural brain research. vol 194. issue 2. 2009-02-03. PMID:18675851. |
several neurotransmitters, including glutamate and serotonin, modulate defensive behaviors related to anxiety in the rat dorsal periaqueductal gray (pag). |
2009-02-03 |
2023-08-12 |
rat |
| Jaime M Monti, Héctor Janto. The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking. Progress in brain research. vol 172. 2009-01-15. PMID:18772053. |
recently, da neurons were characterised in the ventral periaqueductal grey matter (vpag) that express fos protein during w. lesioning of these cells resulted in an increase of sws and rems, which led to the proposal that vpag da neurons may play a role in the promotion of w. systemic injection of full agonists at postsynaptic 5-ht(1a) (8-oh-dpat, flesinoxan), 5-ht(1b) (cgs 12066b, cp-94,253), 5-ht(2a/2c) (doi, dom) and 5-ht(3) (m-chlorophenylbiguanide) receptors increases w and reduces sws and rems. |
2009-01-15 |
2023-08-12 |
Not clear |
| Valquíria Camin de Bortoli, Regina Lúcia Nogueira, Hélio Zangross. Alprazolam potentiates the antiaversive effect induced by the activation of 5-HT(1A) and 5-HT (2A) receptors in the rat dorsal periaqueductal gray. Psychopharmacology. vol 198. issue 3. 2008-11-17. PMID:18446327. |
alprazolam potentiates the antiaversive effect induced by the activation of 5-ht(1a) and 5-ht (2a) receptors in the rat dorsal periaqueductal gray. |
2008-11-17 |
2023-08-12 |
rat |
| Valquíria Camin de Bortoli, Regina Lúcia Nogueira, Hélio Zangross. Alprazolam potentiates the antiaversive effect induced by the activation of 5-HT(1A) and 5-HT (2A) receptors in the rat dorsal periaqueductal gray. Psychopharmacology. vol 198. issue 3. 2008-11-17. PMID:18446327. |
serotonin in the dorsal periaqueductal gray (dpag) through the activation of 5-ht(1a) and 5-ht(2a) receptors inhibits escape, a defensive behavior associated with panic attacks. |
2008-11-17 |
2023-08-12 |
rat |
| L W Lim, Y Temel, T Sesia, R Vlamings, V Visser-Vandewalle, H W M Steinbusch, A Bloklan. Buspirone induced acute and chronic changes of neural activation in the periaqueductal gray of rats. Neuroscience. vol 155. issue 1. 2008-11-05. PMID:18588948. |
5-ht(1a) modulation within the midbrain periaqueductal gray (pag) is closely associated with anxiety- or panic-like behavior. |
2008-11-05 |
2023-08-12 |
rat |
| João Manuel Braz, Allan I Basbau. Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits. The Journal of comparative neurology. vol 507. issue 6. 2008-03-27. PMID:18273889. |
by contrast, we found no evidence that neurons of the midbrain periaqueductal gray that project to the rvm are postsynaptic to midbrain or medullary 5ht neurons. |
2008-03-27 |
2023-08-12 |
Not clear |
| Vanessa Nunes-de-Souza, Ricardo Luiz Nunes-de-Souza, Robert John Rodgers, Azair Canto-de-Souz. 5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice. Behavioural brain research. vol 187. issue 1. 2008-03-11. PMID:17935799. |
thus, whereas stimulation of 5-ht 1a or 5-ht2 receptors in the limbic forebrain (amygdala, hippocampus) enhances anxiety-like responding in rodents, activation of corresponding receptor populations in the midbrain periaqueductal grey (pag) more often than not reduce anxiety-like behaviour. |
2008-03-11 |
2023-08-12 |
mouse |
| M A De Souza Silva, L Marchetti, U L M Eisel, J P Huston, E Der. NR2C by NR2B subunit exchange in juvenile mice affects emotionality and 5-HT in the frontal cortex. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17054720. |
this nr2c-2b mutant was used to examine whether an nmda-r subunit exchange in juvenile mice would affect emotional behaviors and acetylcholine (ach), dopamine (da) and serotonin (5-ht) content in the frontal cortex (fc) and brain structures, which are part of the brain defense system, such as the periaqueductal grey matter (pag). |
2007-09-19 |
2023-08-12 |
mouse |
| Luciana Chrystine Oliveira, Ana Carolina Broiz, Carlos Eduardo de Macedo, J Landeira-Fernandez, Marcus Lira Brandã. 5-HT2 receptor mechanisms of the dorsal periaqueductal gray in the conditioned and unconditioned fear in rats. Psychopharmacology. vol 191. issue 2. 2007-06-25. PMID:17205316. |
it is well known that 5-ht(2) mechanisms modulate the defensive behavior produced by the stimulation of the dorsal periaqueductal gray (dpag). |
2007-06-25 |
2023-08-12 |
rat |
| Janaina Menezes Zanoveli, Regina Lúcia Nogueira, Hélio Zangross. Enhanced reactivity of 5-HT1A receptors in the rat dorsal periaqueductal gray matter after chronic treatment with fluoxetine and sertraline: evidence from the elevated T-maze. Neuropharmacology. vol 52. issue 4. 2007-06-01. PMID:17313964. |
behavioral evidence indicates that sensitization of 5-ht1a and 5-ht2a receptors in the dorsal periaqueductal gray (dpag) may underlie the therapeutic effect of serotonin reuptake inhibitors (sris) in panic disorder. |
2007-06-01 |
2023-08-12 |
rat |
| Kazuhiro Nakamura, Shaun F Morriso. Central efferent pathways mediating skin cooling-evoked sympathetic thermogenesis in brown adipose tissue. American journal of physiology. Regulatory, integrative and comparative physiology. vol 292. issue 1. 2007-02-08. PMID:16931649. |
skin cooling-evoked thermogenic, metabolic, and heart rate responses were inhibited by bilateral microinjections of bicuculline (gaba(a) receptor antagonist) into the preoptic area (poa), by bilateral microinjections of muscimol (gaba(a) receptor agonist) into the dorsomedial hypothalamic nucleus (dmh), or by microinjection of muscimol, glycine, 8-oh-dpat (5-ht(1a) receptor agonist), or kynurenate (nonselective antagonist for ionotropic excitatory amino acid receptors) into the rostral raphe pallidus nucleus (rrpa) but not by bilateral muscimol injections into the lateral/dorsolateral part or ventrolateral part of the caudal periaqueductal gray. |
2007-02-08 |
2023-08-12 |
rat |
| L J Bertoglio, F S Guimarães, H Zangross. Lack of interaction between NMDA and cholecystokinin-2 receptor-mediated neurotransmission in the dorsolateral periaqueductal gray in the regulation of rat defensive behaviors. Life sciences. vol 79. issue 23. 2006-12-21. PMID:16914165. |
several neurotransmitters, including gaba, serotonin, glutamate, and cholecystokinin, modulate defensive behaviors in the dorsolateral periaqueductal gray (dlpag). |
2006-12-21 |
2023-08-12 |
rat |
| N C Coimbra, R De Oliveira, R L Freitas, S J Ribeiro, K G Borelli, R C Pacagnella, J E Moreira, L A da Silva, L L Melo, L O Lunardi, M L Brandã. Neuroanatomical approaches of the tectum-reticular pathways and immunohistochemical evidence for serotonin-positive perikarya on neuronal substrates of the superior colliculus and periaqueductal gray matter involved in the elaboration of the defensive behavior and fear-induced analgesia. Experimental neurology. vol 197. issue 1. 2006-02-08. PMID:16303128. |
immunohistochemical studies showed that the sites in which neuronal perikarya positive to serotonin were identified in intermediate and deep layers of the superior colliculus, and in the dorsal and ventral columns of the periaqueductal gray matter are the same which were activated during the generation of defense behaviors, such as alertness, freezing, and escape reactions, induced by bicuculline. |
2006-02-08 |
2023-08-12 |
rat |
| Valquíria Camin de Bortoli, Regina Lúcia Nogueira, Hélio Zangross. Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16258751. |
administration of 5-hydroxytryptamine (5-ht)1a and 5-ht2a receptor agonists into the dorsal periaqueductal gray (dpag) inhibits escape, a defensive behavior associated with panic attacks. |
2006-01-31 |
2023-08-12 |
rat |
| Letizia Maria Cupini, Paolo Calabres. Medication-overuse headache: pathophysiological insights. The journal of headache and pain. vol 6. issue 4. 2006-01-24. PMID:16362663. |
there are several different theories regarding the aetiology of moh, including: (i) central sensitisation from repetitive activation of nociceptive pathways; (ii) a direct effect of the medication on the capacity of the brain to inhibit pain; (iii) a decrease in blood serotonin due to repetitive medication administration with alteration of serotonin receptors; (iv) cellular adaptation in the brain; and (v) changes in the periaqueductal grey matter. |
2006-01-24 |
2023-08-12 |
Not clear |