| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Lacanà, J K Ganjei, P Vito, L D'Adami. Dissociation of apoptosis and activation of IL-1beta-converting enzyme/Ced-3 proteases by ALG-2 and the truncated Alzheimer's gene ALG-3. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 11. 1997-06-19. PMID:9164928. |
alg-3, a truncated form of the familial alzheimer's disease gene ps2, confers resistance to tcr- and fas-induced apoptosis. |
1997-06-19 |
2023-08-12 |
mouse |
| G A MacGibbon, P A Lawlor, E S Sirimanne, M R Walton, B Connor, D Young, C Williams, P Gluckman, R L Faull, P Hughes, M Draguno. Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098548. |
bax expression in mammalian neurons undergoing apoptosis, and in alzheimer's disease hippocampus. |
1997-06-17 |
2023-08-12 |
rat |
| Q Guo, B L Sopher, K Furukawa, D G Pham, N Robinson, G M Martin, M P Mattso. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 11. 1997-06-10. PMID:9151738. |
alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. |
1997-06-10 |
2023-08-12 |
human |
| F Gray, H Adle-Biassette, Y Levy, L Wingertsmann, C Hery, M Tardie. [Neuronal apoptosis in the course of human immunodeficiency virus infection]. Bulletin de l'Academie nationale de medecine. vol 180. issue 8. 1997-05-08. PMID:9138754. |
we demonstrated neuronal apoptosis in all the aids cases and in the alzheimer's cases. |
1997-05-08 |
2023-08-12 |
human |
| W P Li, H W Lai, S Y Cheng, D T Ye. Somatostatin-positive neurons in the different parts of the brain in normal aging and Alzheimer's disease. Biological signals. vol 5. issue 6. 1997-04-24. PMID:9116800. |
the present work seeks to verify if there is a difference in the number of somatostatin neurons in the cortex between normal aging versus alzheimer patients and secondly if any of these neurons are dying via apoptosis. |
1997-04-24 |
2023-08-12 |
Not clear |
| Y Kitamura, S Shimohama, W Kamoshima, Y Matsuoka, Y Nomura, T Taniguch. Changes of p53 in the brains of patients with Alzheimer's disease. Biochemical and biophysical research communications. vol 232. issue 2. 1997-04-22. PMID:9125193. |
recent studies suggest that cortical neurons and glial cells undergo apoptosis in alzheimer's disease (ad). |
1997-04-22 |
2023-08-12 |
human |
| W Kiatipattanasakul, S Nakamura, M M Hossain, H Nakayama, T Uchino, S Shumiya, N Goto, K Do. Apoptosis in the aged dog brain. Acta neuropathologica. vol 92. issue 3. 1997-02-03. PMID:8870825. |
apoptosis similar to that seen in alzheimer's disease patients was found in the brain of aged dogs by the tunel method of detecting in situ dna fragmentation. |
1997-02-03 |
2023-08-12 |
dog |
| W Kiatipattanasakul, S Nakamura, M M Hossain, H Nakayama, T Uchino, S Shumiya, N Goto, K Do. Apoptosis in the aged dog brain. Acta neuropathologica. vol 92. issue 3. 1997-02-03. PMID:8870825. |
the present study indicates that brain cell apoptosis could account for dementia in aged dogs and suggested that aged dogs may be useful as a simplified animal model for alzheimer's disease in man. |
1997-02-03 |
2023-08-12 |
dog |
| P Vito, B Wolozin, J K Ganjei, K Iwasaki, E Lacanà, L D'Adami. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940094. |
requirement of the familial alzheimer's disease gene ps2 for apoptosis. |
1997-01-09 |
2023-08-12 |
mouse |
| P Vito, B Wolozin, J K Ganjei, K Iwasaki, E Lacanà, L D'Adami. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of biological chemistry. vol 271. issue 49. 1997-01-09. PMID:8940094. |
alg-3, a truncated mouse homologue of the chromosome 1 familial alzheimer's disease gene ps2, rescues t hybridoma 3do cells from t-cell receptor-induced apoptosis by inhibiting fas ligand induction and fas signaling. |
1997-01-09 |
2023-08-12 |
mouse |
| E Paradis, H Douillard, M Koutroumanis, C Goodyer, A LeBlan. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 23. 1997-01-06. PMID:8922409. |
neuronal apoptosis is a suspected cause of neurodegeneration in alzheimer's disease (ad). |
1997-01-06 |
2023-08-12 |
human |
| A J Anderson, J H Su, C W Cotma. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 5. 1997-01-03. PMID:8774439. |
dna damage and apoptosis in alzheimer's disease: colocalization with c-jun immunoreactivity, relationship to brain area, and effect of postmortem delay. |
1997-01-03 |
2023-08-12 |
Not clear |
| A J Anderson, J H Su, C W Cotma. DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 5. 1997-01-03. PMID:8774439. |
many neurons in alzheimer's disease (ad) exhibit terminal deoxynucleotidyl transferase (tdt) labeling for dna strand breaks with a distribution suggestive of apoptosis. |
1997-01-03 |
2023-08-12 |
Not clear |
| B Wolozin, K Iwasaki, P Vito, J K Ganjei, E Lacanà, T Sunderland, B Zhao, J W Kusiak, W Wasco, L D'Adami. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science (New York, N.Y.). vol 274. issue 5293. 1997-01-03. PMID:8939861. |
participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an alzheimer mutation. |
1997-01-03 |
2023-08-12 |
Not clear |
| B Wolozin, K Iwasaki, P Vito, J K Ganjei, E Lacanà, T Sunderland, B Zhao, J W Kusiak, W Wasco, L D'Adami. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science (New York, N.Y.). vol 274. issue 5293. 1997-01-03. PMID:8939861. |
overexpression of the familial alzheimer's disease gene presenilin 2 (ps2) in nerve growth factor-differentiated pc12 cells increased apoptosis induced by trophic factor withdrawal or beta-amyloid. |
1997-01-03 |
2023-08-12 |
Not clear |
| R M Sainz, J C Mayo, H Uría, M Kotler, I Antolín, C Rodriguez, A Menendez-Pelae. The pineal neurohormone melatonin prevents in vivo and in vitro apoptosis in thymocytes. Journal of pineal research. vol 19. issue 4. 1996-10-21. PMID:8789249. |
since apoptosis is a possible mechanism involved in neuronal death shown in several neurodegenerative diseases such as parkinson or alzheimer's diseases, investigative efforts should be directed to the possible role of melatonin in inhibiting cell death in tissues other that the thymus. |
1996-10-21 |
2023-08-12 |
rat |
| T Yamatsuji, T Okamoto, S Takeda, Y Murayama, N Tanaka, I Nishimot. Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype. The EMBO journal. vol 15. issue 3. 1996-04-30. PMID:8599933. |
expression of v642 app mutant causes cellular apoptosis as alzheimer trait-linked phenotype. |
1996-04-30 |
2023-08-12 |
Not clear |
| T Satou, B J Cummings, C W Cotma. Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593592. |
recently, apoptosis has been suggested to have an important role in the pathogenesis of alzheimer's disease (ad). |
1996-04-11 |
2023-08-12 |
Not clear |
| P Vito, E Lacanà, L D'Adami. Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science (New York, N.Y.). vol 271. issue 5248. 1996-02-27. PMID:8560270. |
interfering with apoptosis: ca(2+)-binding protein alg-2 and alzheimer's disease gene alg-3. |
1996-02-27 |
2023-08-12 |
Not clear |
| P Vito, E Lacanà, L D'Adami. Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science (New York, N.Y.). vol 271. issue 5248. 1996-02-27. PMID:8560270. |
alg-3, a partial complementary dna that is homologous to the familial alzheimer's disease gene stm2, rescues a t cell hybridoma from t cell receptor- and fas-induced apoptosis. |
1996-02-27 |
2023-08-12 |
Not clear |