| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Yang, Limei Wang, Caijun Zhang, Yuqian Guo, Jintao Li, Chao Wu, Jianlin Jiao, Hong Zhen. Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis and neuroinflammation through Wnt/GSK-3β/β-catenin signaling pathway. Chemical biology & drug design. 2022-03-21. PMID:35313087. |
ginsenoside rg1 improves alzheimer's disease by regulating oxidative stress, apoptosis and neuroinflammation through wnt/gsk-3β/β-catenin signaling pathway. |
2022-03-21 |
2023-08-13 |
cat |
| Zhan-Bin Tang, Hong-Ping Chen, Di Zhong, Ji-He Song, Jing-Wei Cao, Mian-Qiao Zhao, Bai-Chao Han, Qiong Duan, Xiao-Meng Sheng, Jia-Lin Yao, Guo-Zhong L. LncRNA RMRP accelerates autophagy-mediated neurons apoptosis through miR-3142/TRIB3 signaling axis in Alzheimer's disease. Brain research. 2022-03-19. PMID:35304105. |
lncrna rmrp accelerates autophagy-mediated neurons apoptosis through mir-3142/trib3 signaling axis in alzheimer's disease. |
2022-03-19 |
2023-08-13 |
human |
| Wen Xu, Yi Huan. Regulation of Inflammatory Cell Death by Phosphorylation. Frontiers in immunology. vol 13. 2022-03-18. PMID:35300338. |
currently, there are many forms of cell death, and several of them, such as necroptosis, pyroptosis and ferroptosis, even apoptosis trigger an inflammatory response by releasing damage-associated molecular patterns (damps), which are involved in the pathogenesis of a variety of human inflammatory diseases, including autoimmunity disease, diabetes, alzheimer's disease and cancer. |
2022-03-18 |
2023-08-13 |
human |
| Oluwaseun Samuel Faborode, Ernest Dalle Writing-Review, Editing, Musa Vuyisile Mabandl. Trauma-like exposure alters neuronal apoptosis, Bin1, Fkbp5 and NR2B expression in an amyloid-beta (1-42) rat model of Alzheimer's disease. Neurobiology of learning and memory. 2022-03-16. PMID:35292372. |
trauma-like exposure alters neuronal apoptosis, bin1, fkbp5 and nr2b expression in an amyloid-beta (1-42) rat model of alzheimer's disease. |
2022-03-16 |
2023-08-13 |
rat |
| Xing Ren, Jiwei Zhang, Yunnan Zhao, Lingzhi Su. Senegenin Inhibits Aβ Neuropsychiatric disease and treatment. vol 18. 2022-03-14. PMID:35280979. |
senegenin inhibits aβ apoptosis and oxidative stress have been considered as key events in the pathogenesis of alzheimer's disease (ad). |
2022-03-14 |
2023-08-13 |
Not clear |
| Chuan Qin, Lin Bai, Yongning Li, Kewei Wan. The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: crosstalk between autophagy and apoptosis. Stem cell research & therapy. vol 13. issue 1. 2022-03-04. PMID:35241159. |
the functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with alzheimer's disease: crosstalk between autophagy and apoptosis. |
2022-03-04 |
2023-08-13 |
Not clear |
| Yu Pang, Wennan Lin, Lan Zhan, Jiawen Zhang, Shicun Zhang, Hongwei Jin, He Zhang, Xiaoli Wang, Xiaoming L. Inhibiting Autophagy Pathway of PI3K/AKT/mTOR Promotes Apoptosis in SK-N-SH Cell Model of Alzheimer's Disease. Journal of healthcare engineering. vol 2022. 2022-02-18. PMID:35178230. |
inhibiting autophagy pathway of pi3k/akt/mtor promotes apoptosis in sk-n-sh cell model of alzheimer's disease. |
2022-02-18 |
2023-08-13 |
human |
| Zhike Zhou, Jun Bai, Shanshan Zhong, Rongwei Zhang, Kexin Kang, Xiaoqian Zhang, Ying Xu, Chuansheng Zhao, Mei Zha. Downregulation of PIK3CB Involved in Alzheimer's Disease via Apoptosis, Axon Guidance, and FoxO Signaling Pathway. Oxidative medicine and cellular longevity. vol 2022. 2022-01-31. PMID:35096262. |
downregulation of pik3cb involved in alzheimer's disease via apoptosis, axon guidance, and foxo signaling pathway. |
2022-01-31 |
2023-08-13 |
Not clear |
| Bilal Cakir, Yoshiaki Tanaka, Ferdi Ridvan Kiral, Yangfei Xiang, Onur Dagliyan, Juan Wang, Maria Lee, Allison M Greaney, Woo Sub Yang, Catherine duBoulay, Mehmet Hamdi Kural, Benjamin Patterson, Mei Zhong, Jonghun Kim, Yalai Bai, Wang Min, Laura E Niklason, Prabir Patra, In-Hyun Par. Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids. Nature communications. vol 13. issue 1. 2022-01-21. PMID:35058453. |
furthermore, in mhcos, we observed reduced expression of aβ-induced expression of genes associated with apoptosis, ferroptosis, and alzheimer's disease (ad) stage iii. |
2022-01-21 |
2023-08-13 |
mouse |
| Xiaohu iMa, Linlin Liu, Jing Men. Expression of concern: MicroRNA-125b promotes neurons cell apoptosis and tau phosphorylation in Alzheimer's disease. Neuroscience letters. vol 769. 2022-01-17. PMID:35034691. |
expression of concern: microrna-125b promotes neurons cell apoptosis and tau phosphorylation in alzheimer's disease. |
2022-01-17 |
2023-08-13 |
Not clear |
| Tao Zhang, Yongfang Xia, Li Hu, Dongmei Chen, Chen-Ling Gan, Long Wang, Yingxue Mei, Guihua Lan, Xindong Shui, Yuan Tian, Ruomeng Li, Mi Zhang, Tae Ho Le. Death-associated protein kinase 1 mediates Aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in Alzheimer's disease. International journal of biological sciences. vol 18. issue 2. 2022-01-10. PMID:35002518. |
death-associated protein kinase 1 mediates aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in alzheimer's disease. |
2022-01-10 |
2023-08-13 |
Not clear |
| Yanqun Cao, Xiangxiang Tan, Quzhe Lu, Kai Huang, Xiaoer Tang, Zhiming H. miR-590-3 and SP1 Promote Neuronal Apoptosis in Patients with Alzheimer's Disease via AMPK Signaling Pathway. Contrast media & molecular imaging. vol 2021. 2022-01-07. PMID:34992508. |
mir-590-3 and sp1 promote neuronal apoptosis in patients with alzheimer's disease via ampk signaling pathway. |
2022-01-07 |
2023-08-13 |
Not clear |
| Zhenwei Gong, Eric Goetzman, Radhika H Muzumda. Cardio-protective role of Humanin in myocardial ischemia-reperfusion. Biochimica et biophysica acta. General subjects. 2021-12-13. PMID:34896254. |
it was first identified in 2001 in the surviving neurons of patient with alzheimer's disease, and since then has been well characterized for its neuro-protective effect through inhibition of apoptosis. |
2021-12-13 |
2023-08-13 |
Not clear |
| Li-Xia Dong, Hai-Lan Bao, Yan-Yun Zhang, Yu Liu, Guo-Wei Zhang, Feng-Mao A. MicroRNA-16-5p/BTG2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in Alzheimer's disease. Brain research bulletin. vol 175. 2021-12-10. PMID:34217799. |
microrna-16-5p/btg2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in alzheimer's disease. |
2021-12-10 |
2023-08-13 |
Not clear |
| Nour S Ereka. Apoptosis and its therapeutic implications in neurodegenerative diseases. Clinical anatomy (New York, N.Y.). vol 35. issue 1. 2021-12-08. PMID:34558138. |
apoptosis has been implicated in the pathogenesis of neurodegenerative diseases, including parkinson disease, alzheimer disease, huntington disease, and amyotrophic lateral sclerosis. |
2021-12-08 |
2023-08-13 |
Not clear |
| Benjamin Ongnok, Thawatchai Khuanjing, Titikorn Chunchai, Patcharapong Pantiya, Sasiwan Kerdphoo, Busarin Arunsak, Wichwara Nawara, Thidarat Jaiwongkam, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn C Chattipakor. Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 3. 2021-12-04. PMID:34312765. |
here, we demonstrated that dox-treated rats manifested conspicuous cognitive deficits and developed chemobrain pathologies as indicated by brain inflammatory and oxidative insults, glial activation, defective mitochondrial homeostasis, increased potential lesions associated with alzheimer's disease, disrupted neurogenesis, loss of dendritic spines, and ultimately neuronal death through both apoptosis and necroptosis. |
2021-12-04 |
2023-08-13 |
rat |
| Fatemeh Panahzadeh, Rahim Mirnasouri, Masoud Rahmat. Exercise and Syzygium aromaticum reverse memory deficits, apoptosis and mitochondrial dysfunction of the hippocampus in Alzheimer's disease. Journal of ethnopharmacology. 2021-12-02. PMID:34856360. |
exercise and syzygium aromaticum reverse memory deficits, apoptosis and mitochondrial dysfunction of the hippocampus in alzheimer's disease. |
2021-12-02 |
2023-08-13 |
Not clear |
| Zhijun He, Jianxi Song, Xuexia Li, Xiaoqian Li, Huazhang Zhu, Chong Wu, Wen Xiao, Xiubo Du, Jiazuan Ni, Nan Li, Qiong Li. Bis(ethylmaltolato)oxidovanadium (IV) alleviates neuronal apoptosis through regulating peroxisome proliferator-activated receptor γ in a triple transgenic animal model of Alzheimer's disease. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. vol 26. issue 5. 2021-11-29. PMID:34240269. |
bis(ethylmaltolato)oxidovanadium (iv) alleviates neuronal apoptosis through regulating peroxisome proliferator-activated receptor γ in a triple transgenic animal model of alzheimer's disease. |
2021-11-29 |
2023-08-13 |
mouse |
| Zhijun He, Jianxi Song, Xuexia Li, Xiaoqian Li, Huazhang Zhu, Chong Wu, Wen Xiao, Xiubo Du, Jiazuan Ni, Nan Li, Qiong Li. Bis(ethylmaltolato)oxidovanadium (IV) alleviates neuronal apoptosis through regulating peroxisome proliferator-activated receptor γ in a triple transgenic animal model of Alzheimer's disease. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. vol 26. issue 5. 2021-11-29. PMID:34240269. |
endoplasmic reticulum stress (er stress) plays a critical role in neuronal apoptosis along with the aggravation of alzheimer's disease (ad). |
2021-11-29 |
2023-08-13 |
mouse |
| Yaochen Chuang, Iatkio Van, Yonghua Zhao, Youhua X. Icariin ameliorate Alzheimer's disease by influencing SIRT1 and inhibiting Aβ cascade pathogenesis. Journal of chemical neuroanatomy. vol 117. 2021-11-26. PMID:34407393. |
the decrease of sirtuin1 level would cause alzheimer's disease by means of promoting the amyloidogenic pathway to generate amyloid-β species and thereby triggering amyloid-β cascade reaction, such as tau protein hyperphosphorylation, neuron autophagy, neuroinflammation, oxidative stress, and neuron apoptosis. |
2021-11-26 |
2023-08-13 |
Not clear |