| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muhammad Ikram, Myeung Hoon Jo, Kyonghwan Choe, Amjad Khan, Sareer Ahmad, Kamran Saeed, Min Woo Kim, Myeong Ok Ki. Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions. Cells. vol 10. issue 10. 2021-11-25. PMID:34685699. |
here, we have unveiled the effects of cycloastragenol against aβ (amyloid-beta)-induced oxidative stress, neurogenic dysfunction, activated mitogen-activated protein (map) kinases, and mitochondrial apoptosis in an aβ-induced mouse model of alzheimer's disease (ad). |
2021-11-25 |
2023-08-13 |
mouse |
| Kannan, Jai. Oxidative stress and apoptosis. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 7. issue 3. 2021-11-25. PMID:10996508. |
thus, increasing evidences provide support that oxidative stress and apoptosis are closely linked physiological phenomena and are implicated in pathophysiology of some of the chronic diseases including aids, autoimmunity, cancer, diabetes mellitus, alzheimer's and parkinson's and ischemia of heart and brain. |
2021-11-25 |
2023-08-12 |
Not clear |
| Georgios Katsipis, Elena E Tzekaki, Magda Tsolaki, Anastasia A Pantazak. Salivary GFAP as a potential biomarker for diagnosis of mild cognitive impairment and Alzheimer's disease and its correlation with neuroinflammation and apoptosis. Journal of neuroimmunology. vol 361. 2021-11-24. PMID:34655990. |
salivary gfap as a potential biomarker for diagnosis of mild cognitive impairment and alzheimer's disease and its correlation with neuroinflammation and apoptosis. |
2021-11-24 |
2023-08-13 |
Not clear |
| Cong Yan, Hongwei Yu, Yao Liu, Pei Wu, Chunlei Wang, Hongbo Zhao, Kongbin Yang, Qi Shao, Yingqiang Zhong, Wenyang Zhao, Jingwei Li, Nan Liu, Jinglong Di, Chen Li, Luhao Bao, Cheng Ga. c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway. Journal of molecular neuroscience : MN. vol 71. issue 12. 2021-11-19. PMID:33786723. |
c-abl has been reported to promote neuronal apoptosis in alzheimer's disease and cerebral ischemia, but its role in sah had not been illuminated until now. |
2021-11-19 |
2023-08-13 |
Not clear |
| Emily A Borden, Matthew Furey, Nicholas J Gattone, Vedangi D Hambardikar, Xiao Hua Liang, Ernest R Scoma, Antonella Abou Samra, LaKeshia R D-Gary, Dayshaun J Dennis, Daniel Fricker, Cindy Garcia, ZeCheng Jiang, Shariq A Khan, Dheenadhayalan Kumarasamy, Hasmitha Kuppala, Savannah Ringrose, Evan J Rosenheim, Kimberly Van Exel, Hemanth Sai Vudhayagiri, Jiarui Zhang, Zhaowen Zhang, Mariona Guitart-Mampel, Pedro Urquiza, Maria E Solesi. Is there a link between inorganic polyphosphate (polyP), mitochondria, and neurodegeneration? Pharmacological research. vol 163. 2021-11-17. PMID:33010423. |
mitochondrial dysfunction - including increased apoptosis, calcium and protein dyshomeostasis within the organelle, and dysfunctional bioenergetics and oxidative status - is a common, early feature in all the major neurodegenerative diseases, including alzheimer's disease (ad) and parkinson's disease (pd). |
2021-11-17 |
2023-08-13 |
Not clear |
| Yongjie Xu, Shengju Liu, Liying Zhu, Longguang Dai, Wen Qian, Jingzhi Zhang, Xing Li, Wei Pa. Green tea protects against hippocampal neuronal apoptosis in diabetic encephalopathy by inhibiting JNK/MLCK signaling. Molecular medicine reports. vol 24. issue 2. 2021-11-12. PMID:34132368. |
in neurodegenerative diseases, including alzheimer's disease and parkinson's disease, activation of the jnk signaling pathway promotes neuronal apoptosis. |
2021-11-12 |
2023-08-13 |
rat |
| Jie Qu, Xiaowei Xiong, Gulibaha Hujie, Jun Ren, Lihui Yan, Liqun M. MicroRNA-132-3p alleviates neuron apoptosis and impairments of learning and memory abilities in Alzheimer's disease by downregulation of HNRNPU stabilized BACE1. Cell cycle (Georgetown, Tex.). vol 20. issue 21. 2021-11-12. PMID:34585626. |
microrna-132-3p alleviates neuron apoptosis and impairments of learning and memory abilities in alzheimer's disease by downregulation of hnrnpu stabilized bace1. |
2021-11-12 |
2023-08-13 |
Not clear |
| Oluwaseun Samuel Faborode, Ernest Dalle, Musa Vuyisile Mabandl. Exposure to footshock stress downregulates antioxidant genes and increases neuronal apoptosis in an Aβ(1-42) rat model of Alzheimer's disease. Neurochemistry international. vol 150. 2021-11-11. PMID:34419526. |
exposure to footshock stress downregulates antioxidant genes and increases neuronal apoptosis in an aβ(1-42) rat model of alzheimer's disease. |
2021-11-11 |
2023-08-13 |
rat |
| Liansheng Zhang, Yun Qian, Jie Li, Xuan Zhou, He Xu, Jie Yan, Jialing Xiang, Xiang Yuan, Beicheng Sun, Sangram S Sisodia, Yong-Hui Jiang, Xiaohua Cao, Naihe Jing, Anning Li. BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology. iScience. vol 24. issue 9. 2021-11-11. PMID:34430820. |
bad-mediated neuronal apoptosis and neuroinflammation contribute to alzheimer's disease pathology. |
2021-11-11 |
2023-08-13 |
mouse |
| Dai-Di Li, Chang-Qing Zheng, Feng Zhang, Jing-Shan Sh. Potential neuroprotection by Neural regeneration research. vol 17. issue 5. 2021-11-10. PMID:34558510. |
the mechanisms by which dendrobium nobile lindl alkaloid has been reported to improve cognitive dysfunction in alzheimer's disease animal models may be associated with extracellular amyloid plaque production, regulation of tau protein hyperphosphorylation, inhibition of neuroinflammation and neuronal apoptosis, activation of autophagy, and enhanced synaptic connections. |
2021-11-10 |
2023-08-13 |
Not clear |
| Feng Zhang, Yanyun Xu, Liye Shen, Junjie Huang, Songtao Xu, Jiaying Li, Zhichao Sun, Jiangmin He, Minli Chen, Yongming Pa. GuanXinNing Tablet Attenuates Alzheimer's Disease via Improving Gut Microbiota, Host Metabolites, and Neuronal Apoptosis in Rabbits. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-11-10. PMID:34745305. |
guanxinning tablet attenuates alzheimer's disease via improving gut microbiota, host metabolites, and neuronal apoptosis in rabbits. |
2021-11-10 |
2023-08-13 |
Not clear |
| Ran Gu, Rui Liu, Lu Wang, Man Tang, Shi-Rong Li, Xiao H. LncRNA RPPH1 attenuates Aβ The International journal of neuroscience. vol 131. issue 5. 2021-11-09. PMID:32336203. |
lncrna rpph1 attenuates aβ the durative endoplasmic reticulum stress (ers) and subsequent apoptosis contributes to the development and progression of alzheimer's disease (ad). |
2021-11-09 |
2023-08-13 |
Not clear |
| Chun-Na Lan, Wei-Jun Cai, Jie Shi, Zhong-Jie Y. MAPK inhibitors protect against early‑stage osteoarthritis by activating autophagy. Molecular medicine reports. vol 24. issue 6. 2021-10-22. PMID:34590154. |
mitogen‑activated protein kinases (mapks) regulate multiple cellular processes, including proliferation, differentiation and apoptosis, in certain diseases, such as cancer, diabetes and alzheimer's disease. |
2021-10-22 |
2023-08-13 |
rabbit |
| Xiong Li, Yangkai Lin, Xu Meng, Yangping Qiu, Bo H. An L IEEE journal of biomedical and health informatics. vol 25. issue 9. 2021-10-21. PMID:34181562. |
the notch signaling pathway and apoptosis pathway have been reported to be related to the formation of alzheimer's disease. |
2021-10-21 |
2023-08-13 |
Not clear |
| Vivek Kumar Sharma, Thakur Gurjeet Singh, Shareen Singh, Nikhil Garg, Sonia Dhima. Apoptotic Pathways and Alzheimer's Disease: Probing Therapeutic Potential. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34386919. |
alzheimer's disease (ad) is a fatal, chronic neurodegenerative disorder where apoptosis has a compelling and divergent role. |
2021-10-21 |
2023-08-13 |
Not clear |
| Qi Wu, Zhi-Han Tang, Juan Peng, Ling Liao, Li-Hong Pan, Chun-Yan Wu, Zhi-Sheng Jiang, Gui-Xue Wang, Lu-Shan Li. The dual behavior of PCSK9 in the regulation of apoptosis is crucial in Alzheimer's disease progression (Review). Biomedical reports. vol 2. issue 2. 2021-10-21. PMID:24649090. |
the dual behavior of pcsk9 in the regulation of apoptosis is crucial in alzheimer's disease progression (review). |
2021-10-21 |
2023-08-12 |
human |
| Lara Milane, Saket Dolare, Tanjheela Jahan, Mansoor Amij. Mitochondrial nanomedicine: Subcellular organelle-specific delivery of molecular medicines. Nanomedicine : nanotechnology, biology, and medicine. vol 37. 2021-10-07. PMID:34175455. |
mitochondrial dysfunction contributes to many diseases, for example, β-amyloid has been shown to interfere with mitochondrial protein import and induce apoptosis in alzheimer's disease while some forms of parkinson's disease are associated with dysfunctional mitochondrial pink1 and parkin proteins. |
2021-10-07 |
2023-08-13 |
Not clear |
| Jan Homolak, Ana Babic Perhoc, Ana Knezovic, Jelena Osmanovic Barilar, Fatma Koc, Catherine Stanton, R Paul Ross, Melita Salkovic-Petrisi. Disbalance of the duodenal epithelial cell turnover and apoptosis accompanies insensitivity of intestinal redox homeostasis to inhibition of the brain glucose-dependent insulinotropic polypeptide receptors in a rat model of sporadic Alzheimer's disease. Neuroendocrinology. 2021-10-04. PMID:34607331. |
disbalance of the duodenal epithelial cell turnover and apoptosis accompanies insensitivity of intestinal redox homeostasis to inhibition of the brain glucose-dependent insulinotropic polypeptide receptors in a rat model of sporadic alzheimer's disease. |
2021-10-04 |
2023-08-13 |
rat |
| Mohammadmehdi Hadipour, Gholam Hossein Meftahi, Mohammad Reza Afarinesh, Gila Pirzad Jahromi, Boshra Hate. Crocin attenuates the granular cells damages on the dentate gyrus and pyramidal neurons in the CA3 regions of the hippocampus and frontal cortex in the rat model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:32534024. |
amyloid β-peptides (aβ) are considered as a major hallmark of alzheimer's disease (ad) that can induce synaptic loss and apoptosis in brain regions, particularly in the cortex and the hippocampus. |
2021-10-01 |
2023-08-13 |
rat |
| Dong-Pei Jia, Song Wang, Bao-Chao Zhang, Fang Fan. Paraptosis triggers mitochondrial pathway-mediated apoptosis in Alzheimer's disease. Experimental and therapeutic medicine. vol 22. issue 5. 2021-10-01. PMID:34594417. |
paraptosis triggers mitochondrial pathway-mediated apoptosis in alzheimer's disease. |
2021-10-01 |
2023-08-13 |
Not clear |